Sensitive determination of d-carnitine as enantiomeric impurity of levo-carnitine in pharmaceutical formulations by capillary electrophoresis-tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 53, Issue 5, 2010, Pages 1217-1223

  Sánchez Hernández, Laura ^a   García Ruiz, Carmen ^a   Crego, Antonio L ^a   Marina, Maria Luisa ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Capillary electrophoresis; Carnitine; Enantiomeric purity; Mass spectrometry; Pharmaceutical formulations; Validation

Indexed keywords

9 FLUORENYLMETHYL CHLOROFORMATE; CARNITINE; WATER;

ACCURACY; AMPOULE; ARTICLE; CAPILLARY ELECTROPHORESIS; DERIVATIZATION; DILUTION; DRUG DETERMINATION; DRUG FORMULATION; DRUG IMPURITY; ELECTROSPRAY MASS SPECTROMETRY; ENANTIOMER; EXTRACTION; PRIORITY JOURNAL; QUALITY CONTROL; RACEMIC MIXTURE; TABLET; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

CARNITINE; CHEMISTRY, PHARMACEUTICAL; DRUG CONTAMINATION; ELECTROPHORESIS, CAPILLARY; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

EID: 77955918705     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.03.031     Document Type: Article

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