|
Volumn 66, Issue 4, 2010, Pages 737-743
|
Pharmacokinetics of orally administered ABT-751 in children with neuroblastoma and other solid tumors
|
Author keywords
Neuroblastoma; Pharmacokinetics; Tubulin binding agent
|
Indexed keywords
DRUG METABOLITE;
N [2 [(4 HYDROXYPHENYL)AMINO] 3 PYRIDINYL] 4 METHOXYBENZENESULFONAMIDE;
GLUCURONIDE;
SULFATE;
SULFONAMIDE;
ABDOMINAL PAIN;
ADOLESCENT;
ADULT;
AGE;
AREA UNDER THE CURVE;
ARTICLE;
CHILD;
CLINICAL TRIAL;
CONSTIPATION;
CONTROLLED CLINICAL TRIAL;
CONTROLLED STUDY;
DEHYDRATION;
DOSE RESPONSE;
DRUG BIOAVAILABILITY;
DRUG BLOOD LEVEL;
DRUG CAPSULE;
DRUG CLEARANCE;
DRUG DOSAGE FORM COMPARISON;
DRUG DOSE COMPARISON;
DRUG DOSE ESCALATION;
DRUG DOSE REDUCTION;
DRUG ELIMINATION;
DRUG EXCRETION;
DRUG HALF LIFE;
DRUG URINE LEVEL;
FATIGUE;
FEMALE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HYPERTENSION;
MAJOR CLINICAL STUDY;
MALE;
MAXIMUM PLASMA CONCENTRATION;
MOTOR NEUROPATHY;
MULTIPLE CYCLE TREATMENT;
NAUSEA AND VOMITING;
NEUROBLASTOMA;
PHASE 1 CLINICAL TRIAL;
PRESCHOOL CHILD;
PRIORITY JOURNAL;
SARCOMA;
SCHOOL CHILD;
SENSORY NEUROPATHY;
SOLID TUMOR;
SUSPENSION;
TANDEM MASS SPECTROMETRY;
TIME TO MAXIMUM PLASMA CONCENTRATION;
BIOTRANSFORMATION;
MASS SPECTROMETRY;
METABOLISM;
TREATMENT OUTCOME;
TUMOR RECURRENCE;
DOSAGE SCHEDULE COMPARISON;
DRUG FORMULATION;
DRUG SOLUBILITY;
MULTICENTER STUDY;
NAUSEA;
SENSORIMOTOR NEUROPATHY;
URINARY EXCRETION;
VOMITING;
ADOLESCENT;
AREA UNDER CURVE;
BIOTRANSFORMATION;
CHILD;
CHILD, PRESCHOOL;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DOSE-RESPONSE RELATIONSHIP, DRUG;
FEMALE;
GLUCURONIDES;
HUMANS;
MALE;
MASS SPECTROMETRY;
NEOPLASM RECURRENCE, LOCAL;
NEUROBLASTOMA;
SULFATES;
SULFONAMIDES;
TREATMENT OUTCOME;
|
EID: 77955913113
PISSN: 03445704
EISSN: None
Source Type: Journal
DOI: 10.1007/s00280-009-1218-z Document Type: Article |
Times cited : (18)
|
References (10)
|