Apoptosis and meiotic segregation in ejaculated sperm from Robertsonian translocation carrier patients

Human Reproduction

Volumn 25, Issue 7, 2010, Pages 1631-1642

  Brugnon, F ^a,b   Janny, L ^a,b   Communal, Y ^c   Darcha, C ^b   Szczepaniak, C ^a   Pellestor, F ^d   Vago, P ^a,b   Pons Rejraji, H ^a   Artonne, C ^a   Grizard, G ^a,b  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^c CENTRE JEAN PERRIN   (France)

^d INSERM   (France)

Author keywords

apoptosis; caspase; DNA fragmentation; meiotic segregation; Robertsonian translocation

Indexed keywords

CARBOXYFLUORESCEIN; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR;

APOPTOSIS; ARTICLE; CELL DEATH; CELL MATURATION; CELL ULTRASTRUCTURE; CHROMOSOME SEGREGATION; CRYOPRESERVATION; DNA FRAGMENTATION; FERTILIZATION IN VITRO; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MALE; MALE INFERTILITY; MEIOSIS; OLIGOASTHENOTERATOZOOSPERMIA; ROBERTSONIAN CHROMOSOME TRANSLOCATION; SPERM DONOR; SPERMATOZOON ABNORMALITY;

ROBERTSONIA;

EID: 77955895419     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deq113     Document Type: Article

References (58)

1. Anton E, Blanco J, Egozcue J, Vidal F. Sperm FISH studies in seven male carriers of Robertsonian translocation t(13;14)(q10;q10). Hum Reprod 2004;19:1345-1351.
2. Arama E, Agapite J, Steller H. Caspase activity and a specific cytochrome c are required for sperm differentiation in drosophila. Dev Cell 2003; 4:687-697.
3. Aziz N, Said T, Paasch U, Agarwal A. The relationship between human sperm apoptosis, morphology and the sperm deformity index. Hum Reprod 2007;22:1413-1419.
4. Baccetti B, Collodel G, Piomboni P. Apoptosis in human ejaculated sperm cells (notulae seminologicae 9). J Submicrosc Cytol Pathol 1996; 28:587-596.
5. Baccetti B, Capitani S, Collodel G, Estenoz M, Gambera L, Piomboni P. Infertile spermatozoa in a human carrier of robertsonian translocation 14;22. Fertil Steril 2002;78:1127-1130.
6. Baccetti B, Collodel G, Marzella R, Moretti E, Piomboni P, Scapigliati G, Serafini F. Ultrastructural studies of spermatozoa from infertile males with Robertsonian translocations and 18, X, Y aneuploidies. Hum Reprod 2005;20:2295-2300.
7. Bennets LE, Aitken RJ. A comparative study of oxidative DNA damage in mammalian spermatozoa. Mol Reprod Dev 2005;71:77-87.
8. Brugnon F, Van Assche E, Veheyen G, Sion B, Boucher D, Pouly JL, Janny L, Devroey P, Liebaers I, Van Steurteghem A. Study of apoptosis and meiotic segregation in ejaculated sperm of chromosomal translocation carrier patients. Hum Reprod 2006;21:685-693.
9. Brugnon F, Ouchchane L, Verheyen G, Communal Y, Van der Elst J, Tournaye H, Janny L, Grizard G. Fluorescence microscopy and flow cytometry in measuring activated caspases in human spermatozoa. Int J Androl 2009a;32:265-273.
10. Brugnon F,Janny L, Artonne C,Sion B,Pouly JL, Grizard G. Activated caspases in thawed epididymal and testicular spermatozoa of patients with congenital bilateral absence of the vas deferens and intracytoplasmic sperm injection outcome. Fertil Steril 2009b;92:557-564.
11. Burgoyne PS, Mahadevaiah SK, Turner JMA. The consequences of asynapsis for mammalian meiosis. Nat Rev Genet 2009;10:207-216.
12. Cayli S, Sakkas D, Vigue L, Demir R, Huszar G. Cellular maturity and apoptosis in human sperm: creatine kinase, caspase-3 and Bcl-xl levels in mature and diminished maturity sperm. Mol Hum Reprod 2004;10:365-372.
13. Darzynkiewicy Z, Pozarowski P. All that glitters is not gold: all that FLICA binds is not caspase. A caution in data interpretation-and new opportunities. Cytometry 2007;71A:536-537.
14. David G, Bisson JP, Czyglik F, Jouannet P, Gernigon C. Anomalies morphologiques du spermatozöde humain. J Gynecol Obstet Biol Reprod 1975;4:17-36.
15. De Paula TS, Bertolla RP, Spaine DM, Cunha MA, Schor N, Cedenho AP. Effect of cryopreservation on sperm apoptotic deoxyribonucleic acid fragmentation in patients with ologozoospermia. Fertil Steril 2006; 86:597-600.
16. Eaker S, Pyle A, Cobb J, Hande MA. Evidence for meiotic spindle checkpoint from analysis of spermatocytes from Robertsonian-chromosome heterozygous mice. J Cell Sci 2001;114:2953-2965.
17. Ekert PG, Silke J, Vaux DL. Caspase inhibitors. Cell Death Differ 1999; 6:1081-1086.
18. Escudero T, Abdelhadi I, Sandalinas M, Munné S. Predictive value of sperm fluorescence in situ hybridization analysis on the outcome of preimplantation genetic diagnosis for translocations. Fertil Steril 2003; 79:1528-1534.
19. Fischer U, Janicke RU, Schulze-Osthoff K. Many cutsto ruin: a comprehensive update of caspase substrates. Cell Death Differ 2003;10:76-100.
20. Frydman N, Romana S, Le Lorc'h M, Vekemans M, Frydman R, Tachdjian G. Assisting reproduction of infertile men carrying a Robertsonian translocation. Hum Reprod 2001;16:2274-2277.
21. Gabriel-Robez O, Rumpler Y. The meiotic pairing behaviour in human spermatocytes carrier of chromosome anomalies and their repercussions on reproductive fitness. Ann Genet 1994;39:17-25.
22. ′-monophosphate-dependent, but apoptosis-unrelated, exposure of aminophospholipids at the apical head plasma membrane of boar sperm cells. Biol Reprod 2002;67:340-350.
23. Gorczyca W, Tuziak T, Kram A, Melamed MR, Darzynkiewicz Z. Detection of apoptosis-associated DNA strand breaks in fine needle aspiration biopsies by in situ end labelling of fragmented DNA. Cytometry 1994;15:169-175.
24. Grizard G, Chevalier V, Griveau JF, Le Lannou D, Boucher D. Influence of seminal plasma on cryopreservation of human spermatozoa in a biological material-free medium: study of normal and low-quality semen. Int J Androl 1999;22:190-196.
25. Grizard G, Ouchchane L, Roddier H, Artonne C, Sion B, Vasson MP, Janny L. In vitro alachlor effects on reactive oxygen species generation, motility patterns and apoptosis markers in human spermatozoa. Reprod Toxicol 2007;23:55-62.
26. Grunewald S, Paasch U, Said TM, Sharma RK, Glander HJ, Agarwal A. Caspase activation in human spermatozoa in response to physiological and pathological stimuli. Fertil Steril 2005;83:1106-1112.
27. Grunewald S, Said TM, Paasch U, Glander HJ, Agarwal A. Relationship between sperm apoptosis signalling and oocyte penetration capacity. Int J Androl 2007;31:325-330.
28. Grunewald S, Rasch M, Reinhardt M, Baumann T, Paasch U, Glander HJ. Stability of fluorochrome bases assays to measure subcellular sperm fuctions. Asian J Androl 2008;10:455-459.
29. Guichaoua MR, Quack B, Speed RM, Noel B, Chandley AC, Luciani JM. Infertility in human males with autosomal translocations: meiotic study of a 14;22 Robertsonian translocation. Hum Genet 1990;86: 162-166.
30. Homolka D, Ivanek R, Capkova J, Jansa P, Forejt J. Chromosomal rearrangement interferes with meiotic X chromosome inactivation. Genome Res 2007;17:1431-1437.
31. Johannisson R, Schwinger E, Wolff HH, Vom Ende V, Lohrs U. The effect of 13;14 Robertsonian translocations on germ-cell differentiation in infertile males. Cytogenet Cell Genet 1992;63:151-155.
32. Kotwicka M, Jendraszak M, Warchol JB. Plasma membrane translocation of phosphatidylserine in human spermatozoa. Folia Histochem Cytobiol 2002;40:111-112.
33. Kuzelova K, Grebenova D, Hrkal Z. Labeling of apoptotic JURL-MK1 cells by fluorescent caspase-3 inhibitor FAM-DEVD-fmk occurs mainly at sites different from Caspase-3 active site. Cytometry 2007; 71A:605-611.
34. Marchetti C, Gallego MA, Defossez A, Formstecher P, Marchetti P. Staining of human sperm with fluorochromes-labeled inhibitor of caspases to detect activated caspases: correlation with apoptosis and sperm parameter. Hum Reprod 2004;19:1127-1134.
35. Martin SJ, Reutelingsperger CP, McGahon AJ, Rader JA, van Schie RC, LaFace DM, Green DR. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med 1995;182:1545-1556.
36. Martin G, Sabido O, Durand P, Levy R. Phosphatidylserine externalization in human sperm induced by calcium ionophore A23187: relationship with apoptosis, membrane scrambling and the acrosome reaction. Hum Reprod 2005;20:3459-3468.
37. Moradkhani K, Puechberty J, Bhatt S, Lespinasse J, Vago P, Lefort G, Sarda P, Hamamah S, Pellestor F. Rare Robertsonian translocations and meiotic behaviour: sperm FISH analysis of t(13;15) and t(14;15) translocations: a case report. Hum Reprod 2006;12:3193-3198.
38. Nagata S. Biddable death. Nat Cell Biol 1999;1:E143-E145.
39. Narayan P, Mentzer RM Jr, Lasley RD. Annexin V staining during reperfusion detects cardiomyocytes with unique properties. Am J Physiol Heart Circ Physiol 2001;281:1931-1937.
40. Oehninger S. Presence and significance of somatic cell apoptosis markers in human ejaculated spermatozoa. Reprod Biomed Online 2003; 7:469-476.
41. Paasch U, Sharma RK, Gupta AK, Grunewald S, Mascha EJ, Thomas AJ, Glander HJ, Agarwal A. Cryopreservation and thawing is associated with varying extent of activation of apoptotic machinery in subsets of ejaculated human spermatozoa. Biol Reprod 2004;71:1828-1837.
42. Parvathenani LK, Buescher ES, Chacon-Cruz E, Beebe SJ. Type I cAMP-dependent kinase delays apoptosis in human neutrophils at a site upstream of caspase-3. J Biol Chem 1998;273:6736-6743.
43. Pellestor F, Imbert I, Andréo B, Lefort G. Study of the occurrence of interchromsomal effect in spermatozoa of chrosomal rearrangement carriers by fluorescence in-situ hybridization and primed in-situ labelling techniques. Hum Reprod 2001;16:1155-1164.
44. Perrin A, Caer E, Olivier-Bonet M, Navarro J, Benet J, Amice V, de Braekelleer M. DNA fragmentation and meiotic segregation in sperm of carriers of a chromosomal structural abnormality. Fertil Steril 2009; 92:583-589.
45. Rooney DE, Czepulowski BH (eds). Human Cytogenetics. A Practical Approach. Vol1: Constitutional Analysis. Oxford: IRL Press, 1992.
46. Said TM, Paasch U, Glander HJ, Agarwal A. Role of caspases in male infertility. Hum Reprod Update 2004;10:39-51.
47. Sakkas D, Mariethoz E, St John JC. Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-Mediated pathway. Exp Cell Res 1999;251:350-355.
48. Sakkas D, Moffat O, Manicardi GC, Mariethoz E, Tarozzi N, Bizzaro D. Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis. Biol Reprod 2002;66:1061-1067.
49. Scorrano L, Ashiya M, Buttle K, Weiler S, Oakes SA, Mannella CA, Horsmeyer SJ. A distinct pathway remodels mitochondrial cristae and mobilises cytochrome c during apoptosis. Dev Cell 2002;2:55-67.
50. Sergerie M, Laforest G, Bujan L, Bissonnette F, Bleau G. Sperm DNA fragmentation: threshold value in male fertility. Hum Reprod 2005; 20:3446-3451.
51. Smolewski P, Grabarek J, Halicka HD, Darzynkiewicz Z. Assay of caspase activation in situ combined with probing plasma membrane integrity to detect three distinct stages of apoptosis. J Immunol Methods 2002; 265:111-121.
52. Taatjes DJ, Sobel BE, Budd RC. Morphological and cytochemical determination of cell death by apoptosis. Histochem Cell Biol 2008; 129:33-43.
53. Taylor SL, Weng SL, Fox P, Duran EH, Morshedi MS, Oehninger S, Beebe SJ. Somatic cell apoptosis markers and pathways in ejaculated sperm: potential utility as indicators of sperm quality. Mol Hum Reprod 2004;10:825-834.
54. Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999; 96:245-254.
55. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexinV. J Immunol Methods 1995;184:39-51.
56. Weng SL, Taylor SL, Morshedi M, Schuffner A, Duran EH, Beebe S, Oehninger S. Caspase activity and apoptotic markers in ejaculated human sperm. Mol Hum Reprod 2002;8:984-991.
57. World Health Organiization. WHO Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction, 4th edn. Cambridge: Cambridge University Press, 1999.
58. Wundrich K, Paasch U, Leicht M, Grunewald HJ. Activation of caspases in human spermatozoa during cryopreservation\an immunoblot study. Cell Tissue Bank 2006;7:81-90.