Vitamin B12 counteracts dexamethasone-induced proliferation and apoptosis during key periods of palatogenesis in mice

Annals of Plastic Surgery

Volumn 64, Issue 4, 2010, Pages 466-470

  He, Wei ^a,b   Meng, Tian ^a,b   Lu, Sheng Jun ^a,b   Zheng, Qian ^a,b   Li, Cheng Hao ^a,b   Wu, Min ^c   Shi, Bing ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Apoptosis; Cleft palate; Dexamethasone; Proliferation; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; DEXAMETHASONE; GLUCOCORTICOID; VITAMIN;

ANIMAL; APOPTOSIS; ARTICLE; C57BL MOUSE; CELL PROLIFERATION; CHEMICALLY INDUCED DISORDER; CLEFT PALATE; DISEASE MODEL; DRUG EFFECT; MOUSE; PALATE; PRENATAL DEVELOPMENT;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CLEFT PALATE; DEXAMETHASONE; DISEASE MODELS, ANIMAL; GLUCOCORTICOIDS; MICE; MICE, INBRED C57BL; PALATE; VITAMIN B 12; VITAMINS;

EID: 77955881541     PISSN: 01487043     EISSN: None     Source Type: Journal    
DOI: 10.1097/SAP.0b013e3181b4bc8d     Document Type: Article

References (45)

1. Beaty TH, Wan H, Hetmanski JB, et al. A case-control study of nonsyndromic oral clefts in Maryland. Ann Epidemiol. 2001;11:434-442.
2. Croen LA, Shaw GM, Wasserman CR, et al. Racial and ethnic variations in the prevalence of orofacial clefts in California, 1983-1992. Am J Med Genet. 1998;79:42-47.
3. Itikala PR, Watkins ML, Mulinare J, et al. Maternal multivitamin use and orofacial clefts in offspring. Teratology. 2001;63:79-86.
4. Steegers-Theunissen BP. Maternal nutrition and obstetric outcome. Baillieres Clin Obstet Gynaecol. 1995;9:431-443.
5. Schubert J, Schmidt R, Syska E. B group vitamins and cleft lip and cleft palate. Int J Oral Maxillofac Surg. 2002;31:410-413.
6. Shaw GM, Lammer EJ, Wasserman CR, et al. Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally. Lancet. 1995;346:393-396.
7. Van Rooij IA, Ocké MC, Straatman H, et al. Periconceptional folate intake by supplement and food reduces the risk of nonsyndromic cleft lip with or without cleft palate. Prev Med. 2004;39:689-694.
8. Vujkovic M, Ocke MC, van der Spek PJ, et al. Maternal Western dietary patterns and the risk of developing a cleft lip with or without a cleft palate. Obstet Gynecol. 2007;110:378-384.
9. Weingartner J, Maile S, Proff P, et al. Secondary palatal closure in rats in association with relative maternofetal levels of folic acid, vitamin B12, and homocysteine. Ann Anat. 2007;189:229-233.
10. Dostal M, Schubert J. Further studies on protective effects of vitamins in cyclophosphamide-induced cleft palate. Int J Oral Maxillofac Surg. 1990;19: 308-311.
11. Jacobsson C, Granstrom G. Effects of vitamin B6 on beta- aminoproprionitrile- induced palatal cleft formation in the rat. Cleft Palate Craniofac J. 1997;34:95-100.
12. Elmazar MM, Thiel R, Nau H. Effect of supplementation with folinic acid, vitamin B6, and vitamin B12 on valproic acid-induced teratogenesis in mice. Fundam Appl Toxicol. 1992;18:389-394.
13. Bienengraber V, Malek FA, Moritz KU, et al. Is it possible to prevent cleft palate by prenatal administration of folic acid? An experimental study. Cleft Palate Craniofac J. 2001;38:393-398.
14. Xu Y, Li L, Zhang Z, et al. Effects of folinic acid and Vitamin B12 on ethanol-induced developmental toxicity in mouse. Toxicol Lett. 2006;167: 167-172.
15. Yoneda T, Pratt RM. Vitamin B6 reduces cortisone-induced cleft palate in the mouse. Teratology. 1982;26:255-258.
16. Natsume N, Narukawa T, Kawai T. Teratogenesis of dexamethasone and preventive effect of vitamin B12. Int J Oral Maxillofac Surg. 1986;15:752-755.
17. Tschanz SA, Burri PH. Postnatal lung development and its impairment by glucocorticoids. Pediatr Pulmonol Suppl. 1997;16:247-249.
18. Takahashi LK. Prenatal stress: consequences of glucocorticoids on hippocampal development and function. Int J Dev Neurosci. 1998;16:199-207.
19. Bian X, Briggs MM, Schachat FH, et al. Glucocortioids accelerate the ontogenetic transition of cardiac ventricular myosin heavy-chain isoform expression in the rat: promotion by prenatal exposure to a low dose of dexamethasone. J Dev Physiol. 1992;18:35-42.
20. Slotkin TA, Seidler FJ, Kavlock RJ, et al. Fetal dexamethasone exposure accelerates development of renal function: relationship to dose, cell differentiation and growth inhibition. J Dev Physiol. 1992;17:55-61.
21. Kusanagi T. Dose-response relations of palatal slit, cleft palate, and fetal mortality in mice treated with a glucocorticoid. Teratology. 1983;28:165-168. (Pubitemid 14227776)
22. Chernoff N, Kavlock RJ, Beyer PE, et al. The potential relationship of maternal toxicity, general stress, and fetal outcome. Teratog Carcinog Mutagen. 1987;7:241-253.
23. Furukawa S, Usuda K, Abe M, et al. Histopathological findings of cleft palate in rat embryos induced by triamcinolone acetonide. J Vet Med Sci. 2004;66: 397-402.
24. Potchinsky M, Nugent P, Lafferty C, et al. Effects of dexamethasone on the expression of transforming growth factor-beta in mouse embryonic palatal mesenchymal cells. J Cell Physiol. 1996;166:380-386.
25. Czeizel AE, Toth M, Rockenbauer M. Population-based case control study of folic acid supplementation during pregnancy. Teratology. 1996;53:345-351.
26. Carmichael SL, Shaw GM, Ma C, et al; National Birth Defects Prevention Study. Maternal corticosteroid use and orofacial clefts. Am J Obstet Gynecol. 2007;197:585.e1-585.e7; discussion 683-684, e1-e7.
27. LaBorde JB, Hansen DK, Young JF, et al. Prenatal dexamethasone exposure in rats: effects of dose, age at exposure, and drug-induced hypophagia on malformations and fetal organ weights. Fundam Appl Toxicol. 1992;19:545-554.
28. Carmel R, Green R, Rosenblatt DS, et al. Update on cobalamin, folate, and homocysteine. Hematology Am Soc Hematol Educ Program. 2003;1:62-81.
29. Koury MJ, Ponka P. New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 2004;24:105-131.
30. Ray JG, Meier C, Vermeulen MJ, et al. Association of neural tube defects and folic acid food fortification in Canada. Lancet. 2002;360:2047-2048.
31. Refsum H. Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome. Br J Nutr. 2001;85:S109-S113.
32. Schwammenthal Y, Tanne D. Homocysteine, B-vitamin supplementation, and stroke prevention: from observational to interventional trials. Lancet Neurol. 2004;3:493-495.
33. Stanger O, Herrmann W, Pietrzik K, et al. DACH-LIGA homocysteine (German, Austrian and Swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med. 2003;41:1392-1403. (Pubitemid 37493551)
34. He K, Merchant A, Rimm EB, et al. Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men. Stroke. 2004;35:169-174.
35. Quinlivan EP, McPartlin J, McNulty H, et al. Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet. 2002;359: 227-228.
36. Pratt WB, Aronow L. The effect of glucocorticoids on protein and nucleic acid synthesis in mouse fibroblasts growing in vitro. J Biol Chem. 1966;241: 5244-5250.
37. Zimmerman EF, Andrew F, Kalter H. Glucocorticoid inhibition of RNA synthesis responsible for cleft palate in mice: a model. Proc Natl Acad Sci USA. 1970;67:779-785.
38. Knott L, Hartridge T, Brown NL, et al. Homocysteine oxidation and apoptosis: a potential cause of cleft palate. In Vitro Cell Dev Biol Anim. 2003;39: 98-105.
39. Cuervo R, Valencia C, Chandraratna RA, et al. Programmed cell death is required for palate shelf fusion and is regulated by retinoic acid. Dev Biol. 2002;245:145-156.
40. Takigawa T, Shiota K. Terminal differentiation of palatal medial edge epithelial cells in vitro is not necessarily dependent on palatal shelf contact and midline epithelial seam formation. Int J Dev Biol. 2004;48:307-317.
41. Takahara S, Takigawa T, Shiota K. Programmed cell death is not a necessary prerequisite for fusion of the fetal mouse palate. Int J Dev Biol. 2004;48:39-46.
42. Tudela C, Formoso MA, Martinez T, et al. TGF-beta3 is required for the adhesion and intercalation of medial edge epithelial cells during palate fusion. Int J Dev Biol. 2002;46:333-336.
43. Dudas M, Kim J, Li WY, et al. Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol. 2006;296:298-314.
44. Fitchett JE, Hay ED. Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse. Dev Biol. 1989;131:455-474.
45. Piddington R, Herold R, Goldman AS. Further evidence for a role of arachidonic acid in glucocorticoid teratogenic action in the palate. Proc Soc Exp Biol Med. 1983;174:336-342.