HSP27 controls GATA-1 protein level during erythroid cell differentiation

Blood

Volumn 116, Issue 1, 2010, Pages 85-96

  De Thonel, Aurelie ^a   Vandekerckhove, Julie ^b   Lanneau, David ^a   Selvakumar, Subramaniam ^a   Courtois, Geneviève ^b   Hazoume, Adonis ^a   Brunet, Mathilde ^a   Maurel, Sebastien ^a   Hammann, Arlette ^a   Ribeil, Jean Antoine ^b   Zermati, Yael ^b   Gabet, Anne Sophie ^b   Boyes, Joan ^c   Solary, Eric ^a,d   Hermine, Olivier ^b   Garrido, Carmen ^a,d  

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d DIJON UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; HEAT SHOCK PROTEIN 27; HEMIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEASOME; TRANSCRIPTION FACTOR GATA 1; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; GATA1 PROTEIN, HUMAN; HSPB1 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; INTERLEUKIN 6; LEUPEPTIN; PYRIDINE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; ENZYME PHOSPHORYLATION; ERYTHROID CELL; ERYTHROLEUKEMIA; ERYTHROPOIESIS; EX VIVO STUDY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UBIQUITINATION; ANIMAL; BLOOD; CELL CULTURE; CELL NUCLEUS; CELL STRAIN COS1; CELL STRAIN K 562; CERCOPITHECUS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; RNA INTERFERENCE;

ANIMALS; ANTIGENS, CD34; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; ERYTHROID CELLS; GATA1 TRANSCRIPTION FACTOR; HELA CELLS; HSP27 HEAT-SHOCK PROTEINS; HUMANS; IMIDAZOLES; IMMUNOBLOTTING; INTERLEUKIN-6; K562 CELLS; LEUPEPTINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PYRIDINES; RNA INTERFERENCE; TRANSFORMING GROWTH FACTOR BETA; UBIQUITINATION;

EID: 77955877483     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-09-241778     Document Type: Article

References (46)

1. Pevny L, Simon MC, Robertson E, et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature. 1991;349(6306):257-260. (Pubitemid 21912061)
2. Ferreira R, Ohneda K, Yamamoto M, Philipsen S. GATA1 function, a paradigm for transcription factors in hematopoiesis. Mol Cell Biol. 2005;25(4):1215- 1227. (Pubitemid 40204902)
3. Weiss MJ, Orkin SH. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci U S A. 1995;92(21):9623-9627.
4. Gregory T, Yu C, Ma A, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression. Blood. 1999;94(1):87-96. (Pubitemid 29300137)
5. Motoyama N, Kimura T, Takahashi T, Watanabe T, Nakano T. bcl-x prevents apoptotic cell death of both primitive and definitive erythrocytes at the end of maturation. J Exp Med. 1999;189(11):1691-1698. (Pubitemid 29272685)
6. De Maria R, Zeuner A, Eramo A, et al. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature. 1999;401(6752):489-493. (Pubitemid 129515788)
7. Gregoli PA, Bondurant MC. Function of caspases in regulating apoptosis caused by erythropoietin deprivation in erythroid progenitors. J Cell Physiol. 1999;178(2):133-143.
8. Zermati Y, Garrido C, Amsellem S, et al. Caspase activation is required for terminal erythroid differentiation. J Exp Med. 2001;193(2):247-254. (Pubitemid 32524456)
9. Kolbus A, Pilat S, Husak Z, et al. Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J Exp Med. 2002;196(10):1347-1353. (Pubitemid 35375553)
10. Carlile GW, Smith DH, Wiedmann M. Caspase-3 has a nonapoptotic function in erythroid maturation. Blood. 2004;103(11):4310-4316. (Pubitemid 38685378)
11. Ribeil JA, Zermati Y, Vandekerckhove J, et al. Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1. Nature. 2007;445(7123):102-105. (Pubitemid 46067309)
12. Lanneau D, Brunet M, Frisan E, Solary E, Fontenay M, Garrido C. Heat shock proteins: essential proteins for apoptosis regulation. J Cell Mol Med. 2008;12(3):743-761.
13. Parcellier A, Schmitt E, Gurbuxani S, et al. HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation. Mol Cell Biol. 2003;23(16):5790-5802. (Pubitemid 36951341)
14. Parcellier A, Brunet M, Schmitt E, et al. HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells. FASEB J. 2006;20(8):1179-1181.
15. Garrido C, Solary E. A role of HSPs in apoptosis through "protein triage"? Cell Death Differ. 2003;10(6):619-620.
16. Whyatt DJ, Karis A, Harkes IC, et al. The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery. Genes Funct. 1997;1(1):11-24.
17. Whyatt D, Lindeboom F, Karis A, et al. An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells. Nature. 2000;406(6795):519-524. (Pubitemid 30625736)
18. Hung HL, Lau J, Kim AY, Weiss MJ, Blobel GA. CREB-Binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites. Mol Cell Biol. 1999;19(5):3496-3505. (Pubitemid 29193809)
19. Hernandez-Hernandez A, Ray P, Litos G, et al. Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1. EMBO J. 2006;25(14):3264-3274. (Pubitemid 44141785)
20. Rutherford TR, Clegg JB, Weatherall DJ. K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin. Nature. 1979;280(5718):164-165.
21. Gambari R, Raschella G, Biagini R, et al. Predominant expression of zeta and epsilon globin genes in human leukemia K-562(S6) variant cell line. Experientia. 1983;39(4):415-416. (Pubitemid 13122909)
22. Fields S, Song O. A novel genetic system to detect protein-protein interactions. Nature. 1989;340(6230):245-246. (Pubitemid 19171591)
23. Chien CT, Bartel PL, Sternglanz R, Fields S. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc Natl Acad Sci U S A. 1991;88(21):9578-9582. (Pubitemid 21915674)
24. Panzenbock B, Bartunek P, Mapara MY, Zenke M. Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro. Blood. 1998;92(10):3658-3668. (Pubitemid 28525191)
25. Landry J, Lambert H, Zhou M, et al. Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem. 1992;267(2):794-803.
26. Stokoe D, Engel K, Campbell DG, Cohen P, Gaestel M. Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett. 1992;313(3):307-313.
27. Maizels ET, Peters CA, Kline M, Cutler RE Jr, Shanmugam M, Hunzicker-Dunn M. Heat-shock protein-25/27 phosphorylation by the delta isoform of protein kinase C. Biochem J. 1998;332(Pt 3):703-712. (Pubitemid 28306696)
28. Uddin S, Ah-Kang J, Ulaszek J, Mahmud D, Wickrema A. Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells. Proc Natl Acad Sci U S A. 2004;101(1):147-152. (Pubitemid 38084218)
29. Weiss MJ, dos Santos CO. Chaperoning erythropoiesis. Blood. 2009;113(10):2136-2144.
30. Orkin SH. Embryonic stem cells and transgenic mice in the study of hematopoiesis. Int J Dev Biol. 1998;42(7):927-934.
31. Welchman RL, Gordon C, Mayer RJ. Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat Rev Mol Cell Biol. 2005;6(8):599-609. (Pubitemid 41081264)
32. Garrido C, Mehlen P, Fromentin A, et al. Inconstant association between 27-kDa heat-shock protein (Hsp27) content and doxorubicin resistance in human colon cancer cells. The doxorubicin-protecting effect of Hsp27. Eur J Biochem. 1996;237(3):653-659. (Pubitemid 26157653)
33. Rouse J, Cohen P, Trigon S, et al. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell. 1994;78(6):1027-1037. (Pubitemid 24292330)
34. Bruey JM, Paul C, Fromentin A, et al. Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo. Oncogene. 2000;19(42):4855-4863.
35. During RL, Gibson BG, Li W, et al. Anthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation. EMBO J. 2007;26(9):2240-2250. (Pubitemid 46685867)
36. Charette SJ, Lavoie JN, Lambert H, Landry J. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Mol Cell Biol. 2000;20(20):7602-7612.
37. Navas TA, Mohindru M, Estes M, et al. Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors. Blood. 2006;108(13):4170-4177. (Pubitemid 44913289)
38. Joanisse DR, Inaguma Y, Tanguay RM. Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster. Biochem Biophys Res Commun. 1998;244(1):102-109. (Pubitemid 28419907)
39. Liberek K, Lewandowska A, Zietkiewicz S. Chaperones in control of protein disaggregation. EMBO J. 2008;27(2):328-335.
40. Sinsimer KS, Gratacos FM, Knapinska AM, et al. Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay. Mol Cell Biol. 2008;28(17):5223-5237.
41. Jaattela M. Escaping cell death: survival proteins in cancer. Exp Cell Res. 1999;248(1):30-43. (Pubitemid 29393927)
42. Didelot C, Lanneau D, Brunet M, et al. Anticancer therapeutic approaches based on intracellular and extracellular heat shock proteins. Curr Med Chem. 2007;14(27):2839-2847. (Pubitemid 350201651)
43. Patmasiriwat P, Fraizer G, Kantarjian H, Saunders GF. WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia. Leukemia. 1999;13(6):891-900. (Pubitemid 29292140)
44. Fadilah SA, Cheong SK, Roslan H, Rozie-Hanisa M, Yen GK. GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome. Leukemia. 2002;16(8):1563-1565.
45. Peng C, Li D, Li S. Heat shock protein 90: a potential therapeutic target in leukemic progenitor and stem cells harboring mutant BCR-ABL resistant to kinase inhibitors. Cell Cycle. 2007;6(18):2227-2231. (Pubitemid 47547697)
46. Taldone T, Gozman A, Maharaj R, Chiosis G. Targeting Hsp90: small-molecule inhibitors and their clinical development. Curr Opin Pharmacol. 2008;8(4):370-374.