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Volumn 89, Issue 4, 2010, Pages 266-274

The etiology of cleft palate: A 50-year search for mechanistic and molecular understanding

Author keywords

Birth defects; Cleft palate; Palatogenesis

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CORTISONE; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR RECEPTOR; HYDROCORTISONE; RETINOL; TERATOGENIC AGENT; TRANSFORMING GROWTH FACTOR BETA3; TRIAMCINOLONE;

EID: 77955871792     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.20252     Document Type: Review
Times cited : (22)

References (62)
  • 1
    • 77955866197 scopus 로고    scopus 로고
    • Experimental models for the study of oral clefts
    • Wyszynski DF, editor. New York: Oxford University Press
    • Abbott BD. 2002. Experimental models for the study of oral clefts. In: Wyszynski DF, editor. Cleft lip and palate: from origin to treatment. New York: Oxford University Press. p 193-202.
    • (2002) Cleft Lip and Palate: From Origin to Treatment , pp. 193-202
    • Abbott, B.D.1
  • 2
    • 18144372714 scopus 로고    scopus 로고
    • Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alpha
    • Abbott BD, Best DS, Narotsky MG. 2005a. Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alpha. Birth Defects Res A Clin Mol Teratol 73:204-217.
    • (2005) Birth Defects Res A Clin Mol Teratol , vol.73 , pp. 204-217
    • Abbott, B.D.1    Best, D.S.2    Narotsky, M.G.3
  • 3
    • 20544456909 scopus 로고    scopus 로고
    • Effects of epidermal growth factor (EGF), transforming growth factor-alpha (TGFalpha), and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFalpha knockout mouse strains
    • Abbott BD, Buckalew AR, Leffler KE. 2005b. Effects of epidermal growth factor (EGF), transforming growth factor-alpha (TGFalpha), and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFalpha knockout mouse strains. Birth Defects Res A Clin Mol Teratol 73:447-454.
    • (2005) Birth Defects Res A Clin Mol Teratol , vol.73 , pp. 447-454
    • Abbott, B.D.1    Buckalew, A.R.2    Leffler, K.E.3
  • 4
    • 0021910022 scopus 로고
    • Toxic interaction of specific polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo-p-dioxin: Increased incidence of cleft palate in mice
    • Birnbaum LS, Weber H, Harris MW, Lamb JCt, McKinney JD. 1985. Toxic interaction of specific polychlorinated biphenyls and 2,3,7,8- tetrachlorodibenzo-p-dioxin: increased incidence of cleft palate in mice. Toxicol Appl Pharmacol 77:292-302.
    • (1985) Toxicol Appl Pharmacol , vol.77 , pp. 292-302
    • Birnbaum, L.S.1    Weber, H.2    Harris, M.W.3    Lamb, J.Ct.4    McKinney, J.D.5
  • 6
    • 0028989842 scopus 로고
    • Inhibition of TGF-beta 3 (but not TGF-beta 1 or TGF-beta 2) activity prevents normal mouse embryonic palate fusion
    • Brunet CL, Sharpe PM, Ferguson MW. 1995. Inhibition of TGF-beta 3 (but not TGF-beta 1 or TGF-beta 2) activity prevents normal mouse embryonic palate fusion. Int J Dev Biol 39:345-355.
    • (1995) Int J Dev Biol , vol.39 , pp. 345-355
    • Brunet, C.L.1    Sharpe, P.M.2    Ferguson, M.W.3
  • 7
    • 0034953010 scopus 로고    scopus 로고
    • Teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the expression of EGF and/or TGF-alpha
    • Bryant PL, Schmid JE, Fenton SE, Buckalew AR, Abbott BD. 2001. Teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the expression of EGF and/or TGF-alpha. Toxicol Sci 62: 103-114.
    • (2001) Toxicol Sci , vol.62 , pp. 103-114
    • Bryant, P.L.1    Schmid, J.E.2    Fenton, S.E.3    Buckalew, A.R.4    Abbott, B.D.5
  • 8
    • 0026542278 scopus 로고
    • The fate of medial edge epithelial cells during palatal fusion in vitro: An analysis by DiI labelling and confocal microscopy
    • Carette MJ, Ferguson MW. 1992. The fate of medial edge epithelial cells during palatal fusion in vitro: an analysis by DiI labelling and confocal microscopy. Development 114:379-388.
    • (1992) Development , vol.114 , pp. 379-388
    • Carette, M.J.1    Ferguson, M.W.2
  • 9
    • 0000986921 scopus 로고
    • Excessive intake of vitamin A as a cause of congenital anomalies in the rat
    • Cohlan SQ. 1953. Excessive intake of vitamin A as a cause of congenital anomalies in the rat. Science 117:535-536.
    • (1953) Science , vol.117 , pp. 535-536
    • Cohlan, S.Q.1
  • 10
    • 0015149459 scopus 로고
    • Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Courtney KD, Moore JA. 1971. Teratology studies with 2,4,5- trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 20:396-403.
    • (1971) Toxicol Appl Pharmacol , vol.20 , pp. 396-403
    • Courtney, K.D.1    Moore, J.A.2
  • 11
    • 1642514680 scopus 로고    scopus 로고
    • Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesis
    • Cuervo R, Covarrubias L. 2004. Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesis. Development 131:15-24.
    • (2004) Development , vol.131 , pp. 15-24
    • Cuervo, R.1    Covarrubias, L.2
  • 12
    • 0019835822 scopus 로고
    • Cortisone-induced cleft palate in A/J mice: Failure of palatal shelf contact
    • Diewert VM, Pratt RM. 1981. Cortisone-induced cleft palate in A/J mice: failure of palatal shelf contact. Teratology 24:149-162.
    • (1981) Teratology , vol.24 , pp. 149-162
    • Diewert, V.M.1    Pratt, R.M.2
  • 13
    • 0016252201 scopus 로고
    • Morphogenesis of cleft palate induced by exogenous factors. VI. The question of delayed palatal-process horizontalization
    • Dostal M, Jelinek R. 1974. Morphogenesis of cleft palate induced by exogenous factors. VI. The question of delayed palatal-process horizontalization. Teratology 10:47-53.
    • (1974) Teratology , vol.10 , pp. 47-53
    • Dostal, M.1    Jelinek, R.2
  • 14
    • 0014323346 scopus 로고
    • Electron microscope study of palate fusion in mouse embryos
    • Farbman AI. 1968. Electron microscope study of palate fusion in mouse embryos. Dev Biol 18:93-116.
    • (1968) Dev Biol , vol.18 , pp. 93-116
    • Farbman, A.I.1
  • 15
    • 0019590439 scopus 로고
    • Developmental mechanisms in normal and abnormal palate formation with particular reference to the aetiology, pathogenesis and prevention of cleft palate
    • Ferguson MWJ. 1981. Developmental mechanisms in normal and abnormal palate formation with particular reference to the aetiology, pathogenesis and prevention of cleft palate. Br J Orthodont 8:115-137.
    • (1981) Br J Orthodont , vol.8 , pp. 115-137
    • Ferguson, M.W.J.1
  • 16
    • 0023694945 scopus 로고
    • Palate development
    • Ferguson MWJ. 1988. Palate development. Development 103(Suppl):41-60.
    • (1988) Development , vol.103 , Issue.SUPPL. , pp. 41-60
    • Ferguson, M.W.J.1
  • 17
    • 0021695259 scopus 로고
    • Epithelial-mesenchymal interactions during vertebrate palatogenesis
    • Ferguson MWJ, Honig LS. 1984. Epithelial-mesenchymal interactions during vertebrate palatogenesis. Curr Topics Dev Biol 19:137-164.
    • (1984) Curr Topics Dev Biol , vol.19 , pp. 137-164
    • Ferguson, M.W.J.1    Honig, L.S.2
  • 18
    • 0024576714 scopus 로고
    • Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse
    • Fitchett JE, Hay ED. 1989. Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse. Dev Biol 131:455-474.
    • (1989) Dev Biol , vol.131 , pp. 455-474
    • Fitchett, J.E.1    Hay, E.D.2
  • 19
    • 0025287681 scopus 로고
    • Differential expression of TGF beta isoforms in murine palatogenesis
    • Fitzpatrick DR, Denhez F, Kondaiah P, Akhurst RJ. 1990. Differential expression of TGF beta isoforms in murine palatogenesis. Development 109:585-595.
    • (1990) Development , vol.109 , pp. 585-595
    • Fitzpatrick, D.R.1    Denhez, F.2    Kondaiah, P.3    Akhurst, R.J.4
  • 20
    • 0014318344 scopus 로고
    • Workshop on embryology of cleft lip and cleft palate
    • Fraser FC. 1968. Workshop on embryology of cleft lip and cleft palate. Teratology 1:353-358.
    • (1968) Teratology , vol.1 , pp. 353-358
    • Fraser, F.C.1
  • 21
    • 0001033198 scopus 로고
    • Production of congenital defects in the off-spring of pregnant mice treated with cortisone; progress report
    • Fraser FC, Fainstat TD. 1951. Production of congenital defects in the off-spring of pregnant mice treated with cortisone; progress report. Pediatrics 8:527-533.
    • (1951) Pediatrics , vol.8 , pp. 527-533
    • Fraser, F.C.1    Fainstat, T.D.2
  • 22
    • 84965184876 scopus 로고
    • The experimental production of cleft palate with cortisone and other hormones
    • Fraser FC, Kalter H, Walker BE, Fainstat TD. 1954. The experimental production of cleft palate with cortisone and other hormones. J Cell Physiol Suppl 43:237-259.
    • (1954) J Cell Physiol Suppl , vol.43 , pp. 237-259
    • Fraser, F.C.1    Kalter, H.2    Walker, B.E.3    Fainstat, T.D.4
  • 23
    • 0015853242 scopus 로고
    • Spatial relations in the oral cavity of cortisone-treated mouse fetuses during the time of secondary palate closure
    • Greene RM, Kochhar DM. 1973. Spatial relations in the oral cavity of cortisone-treated mouse fetuses during the time of secondary palate closure. Teratology 8:153-161.
    • (1973) Teratology , vol.8 , pp. 153-161
    • Greene, R.M.1    Kochhar, D.M.2
  • 24
    • 13644270443 scopus 로고    scopus 로고
    • Recent advances in understanding transforming growth factor beta regulation of orofacial development
    • Greene RM, Pisano MM. 2005. Recent advances in understanding transforming growth factor beta regulation of orofacial development. Hum Exp Toxicol 24:1-12.
    • (2005) Hum Exp Toxicol , vol.24 , pp. 1-12
    • Greene, R.M.1    Pisano, M.M.2
  • 25
    • 0027076557 scopus 로고
    • Epithelial-mesenchymal transformation during palatal fusion: Carboxyfluorescein traces cells at light and electron microscopic levels
    • Griffith CM, Hay ED. 1992. Epithelial-mesenchymal transformation during palatal fusion: carboxyfluorescein traces cells at light and electron microscopic levels. Development 116:1087-1099.
    • (1992) Development , vol.116 , pp. 1087-1099
    • Griffith, C.M.1    Hay, E.D.2
  • 26
    • 0016740169 scopus 로고
    • The development of rat palatal shelves in vitro. An ultrastructural analysis of the inhibition of epithelial cell death and palate fusion by the epidermal growth factor
    • Hassell JR. 1975. The development of rat palatal shelves in vitro. An ultrastructural analysis of the inhibition of epithelial cell death and palate fusion by the epidermal growth factor. Dev Biol 45:90-102.
    • (1975) Dev Biol , vol.45 , pp. 90-102
    • Hassell, J.R.1
  • 27
    • 0014525137 scopus 로고
    • Ultrastructural changes in the epithelium during fusion of the palatal processes in rats
    • Hayward AF. 1969. Ultrastructural changes in the epithelium during fusion of the palatal processes in rats. Archs Oral Biol 14:661-678.
    • (1969) Archs Oral Biol , vol.14 , pp. 661-678
    • Hayward, A.F.1
  • 28
    • 0016321256 scopus 로고
    • Epithelial morphology during closure of the secondary palate in the rat
    • Hinrichsen CFL, Stevens GS. 1974. Epithelial morphology during closure of the secondary palate in the rat. Archs Oral Biol 19:969-980.
    • (1974) Archs Oral Biol , vol.19 , pp. 969-980
    • Hinrichsen, C.F.L.1    Stevens, G.S.2
  • 29
    • 0015535864 scopus 로고
    • A radioautographic study of deoxyribonucleic acid synthesis in embryonic rat palatal shelf epithelium with reference to the concept of programmed cell death
    • Hudson CD, Shapiro BL. 1973. A radioautographic study of deoxyribonucleic acid synthesis in embryonic rat palatal shelf epithelium with reference to the concept of programmed cell death. Arch Oral Biol 18:77-84.
    • (1973) Arch Oral Biol , vol.18 , pp. 77-84
    • Hudson, C.D.1    Shapiro, B.L.2
  • 30
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J. 1995. Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 11:415-421.
    • (1995) Nat Genet , vol.11 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Shuler, C.3    Warburton, D.4    Bu, D.5    Heisterkamp, N.6    Groffen, J.7
  • 31
    • 0030953268 scopus 로고    scopus 로고
    • Transforming growth factor-beta3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane
    • Kaartinen V, Cui XM, Heisterkamp N, Groffen J, Shuler CF. 1997. Transforming growth factor-beta3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane. Dev Dyn 209:255-260.
    • (1997) Dev Dyn , vol.209 , pp. 255-260
    • Kaartinen, V.1    Cui, X.M.2    Heisterkamp, N.3    Groffen, J.4    Shuler, C.F.5
  • 32
    • 84961028878 scopus 로고
    • Experimental production of congenital malformations in strains of inbred mice by maternal teratment with hypervitaminosis A
    • Kalter H, Warkany J. 1961. Experimental production of congenital malformations in strains of inbred mice by maternal teratment with hypervitaminosis A. Am J Pathol 38:1-21.
    • (1961) Am J Pathol , vol.38 , pp. 1-21
    • Kalter, H.1    Warkany, J.2
  • 33
    • 0013828934 scopus 로고
    • Morphological and autoradiographic studies of cleft palate induced in rat embryos by maternal hypervitaminosis A
    • Kochhar DM, Johnson EM. 1965. Morphological and autoradiographic studies of cleft palate induced in rat embryos by maternal hypervitaminosis A. J Embryol Exp Morphol 14:223-238.
    • (1965) J Embryol Exp Morphol , vol.14 , pp. 223-238
    • Kochhar, D.M.1    Johnson, E.M.2
  • 34
    • 0015385496 scopus 로고
    • The effect of hydrocortisone on the closure of the palatal shelves in two inbred strains of mice in vivo and in vitro
    • Lahti A, Antila E, Saxen L. 1972. The effect of hydrocortisone on the closure of the palatal shelves in two inbred strains of mice in vivo and in vitro. Teratology 6:37-42.
    • (1972) Teratology , vol.6 , pp. 37-42
    • Lahti, A.1    Antila, E.2    Saxen, L.3
  • 37
    • 0028094818 scopus 로고
    • Cytochemical identification of programmed cell death in the fusing fetal mouse palate by specific labelling of DNA fragmentation
    • Berl
    • Mori C, Nakamura N, Okamoto Y, Osawa M, Shiota K. 1994. Cytochemical identification of programmed cell death in the fusing fetal mouse palate by specific labelling of DNA fragmentation. Anat Embryol (Berl) 190:21-28.
    • (1994) Anat Embryol , vol.190 , pp. 21-28
    • Mori, C.1    Nakamura, N.2    Okamoto, Y.3    Osawa, M.4    Shiota, K.5
  • 38
    • 3042842601 scopus 로고    scopus 로고
    • Cleft palate: Players, pathways, and pursuits
    • Murray JC, Schutte BC. 2004. Cleft palate: players, pathways, and pursuits. J Clin Invest 113:1676-1678.
    • (2004) J Clin Invest , vol.113 , pp. 1676-1678
    • Murray, J.C.1    Schutte, B.C.2
  • 39
    • 0019151792 scopus 로고
    • Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development
    • Nexo E, Hollenberg MD, Figueroa A, Pratt RM. 1980. Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development. Proc Natl Acad Sci USA 77:2782-2785.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 2782-2785
    • Nexo, E.1    Hollenberg, M.D.2    Figueroa, A.3    Pratt, R.M.4
  • 40
    • 29544447365 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin
    • Patel RD, Kim DJ, Peters JM, Perdew GH. 2006. The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin. Toxicol Sci 89:75-82.
    • (2006) Toxicol Sci , vol.89 , pp. 75-82
    • Patel, R.D.1    Kim, D.J.2    Peters, J.M.3    Perdew, G.H.4
  • 41
    • 0002646363 scopus 로고
    • Involvement of glucocorticoids and epidermal growth factor in secondary palate development
    • Pratt RM, Christiansen RL, editors. New York: Elsevier
    • Pratt RM, Yoneda T, Silver MH, Salomon DS. 1980. Involvement of glucocorticoids and epidermal growth factor in secondary palate development. In: Pratt RM, Christiansen RL, editors. Current research trends in prenatal craniofacial development. New York: Elsevier. p 235-252.
    • (1980) Current Research Trends in Prenatal Craniofacial Development , pp. 235-252
    • Pratt, R.M.1    Yoneda, T.2    Silver, M.H.3    Salomon, D.S.4
  • 42
    • 0021734055 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced cleft palate in the mouse: Evidence for alterations in palatal shelf fusion
    • Pratt RM, Dencker L, Diewert VM. 1984. 2,3,7,8-Tetrachlorodibenzo-p- dioxin-induced cleft palate in the mouse: evidence for alterations in palatal shelf fusion. Teratog Carcinog Mutagen 4:427-436.
    • (1984) Teratog Carcinog Mutagen , vol.4 , pp. 427-436
    • Pratt, R.M.1    Dencker, L.2    Diewert, V.M.3
  • 44
    • 0013936181 scopus 로고
    • Onset of the acquired potentiality for fusion in the palatal shelves of rats
    • Purtois M. 1966. Onset of the acquired potentiality for fusion in the palatal shelves of rats. J Embryol Exp Morph 16:171-182.
    • (1966) J Embryol Exp Morph , vol.16 , pp. 171-182
    • Purtois, M.1
  • 45
    • 0020821217 scopus 로고
    • Cell release from the palatal shelves and the fusion line
    • Schupbach PM, Schroeder HE. 1983. Cell release from the palatal shelves and the fusion line. J Biol Buccale 11:227-241.
    • (1983) J Biol Buccale , vol.11 , pp. 227-241
    • Schupbach, P.M.1    Schroeder, H.E.2
  • 46
    • 0021730716 scopus 로고
    • Morphological, cellular, and biochemical aspects of differentiation of normal and teratogen-treated palate in hamster and chick embryos
    • Shah RM. 1984. Morphological, cellular, and biochemical aspects of differentiation of normal and teratogen-treated palate in hamster and chick embryos. Curr Topics Dev Biol 19:103-135.
    • (1984) Curr Topics Dev Biol , vol.19 , pp. 103-135
    • Shah, R.M.1
  • 47
    • 0026353631 scopus 로고
    • Molecular and morphologic changes during the epithelial-mesenchymal transformation of palatal shelf medial edge epithelium in vitro
    • Shuler CF, Guo Y, Majumder A, Luo RY. 1991. Molecular and morphologic changes during the epithelial-mesenchymal transformation of palatal shelf medial edge epithelium in vitro. Int J Dev Biol 35:463-472.
    • (1991) Int J Dev Biol , vol.35 , pp. 463-472
    • Shuler, C.F.1    Guo, Y.2    Majumder, A.3    Luo, R.Y.4
  • 48
    • 0026481963 scopus 로고
    • Medial edge epithelium fate traced by cell lineage analysis during epithelial-mesenchymal transformation in vivo
    • Shuler CF, Halpern DE, Guo Y, Sank AC. 1992. Medial edge epithelium fate traced by cell lineage analysis during epithelial-mesenchymal transformation in vivo. Dev Biol 154:318-330.
    • (1992) Dev Biol , vol.154 , pp. 318-330
    • Shuler, C.F.1    Halpern, D.E.2    Guo, Y.3    Sank, A.C.4
  • 49
    • 0014310441 scopus 로고
    • Fine structure of midline epithelium in the developing palate of the mouse
    • Smiley GR, Dixon AD. 1968. Fine structure of midline epithelium in the developing palate of the mouse. Anat Rec 161:293-310.
    • (1968) Anat Rec , vol.161 , pp. 293-310
    • Smiley, G.R.1    Dixon, A.D.2
  • 50
    • 1342280610 scopus 로고    scopus 로고
    • Programmed cell death is not a necessary prerequisite for fusion of the fetal mouse palate
    • Takahara S, Takigawa T, Shiota K. 2004. Programmed cell death is not a necessary prerequisite for fusion of the fetal mouse palate. Int J Dev Biol 48:39-46.
    • (2004) Int J Dev Biol , vol.48 , pp. 39-46
    • Takahara, S.1    Takigawa, T.2    Shiota, K.3
  • 51
    • 0032823873 scopus 로고    scopus 로고
    • Pathogenesis of cleft palate in TGF-beta3 knockout mice
    • Taya Y, O'Kane S, Ferguson MW. 1999. Pathogenesis of cleft palate in TGF-beta3 knockout mice. Development 126:3869-3879.
    • (1999) Development , vol.126 , pp. 3869-3879
    • Taya, Y.1    O'Kane, S.2    Ferguson, M.W.3
  • 52
    • 16844379900 scopus 로고    scopus 로고
    • Transforming growth factor-beta3 restores fusion in palatal shelves exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Thomae TL, Stevens EA, Bradfield CA. 2005. Transforming growth factor-beta3 restores fusion in palatal shelves exposed to 2,3,7,8- tetrachlorodibenzo-p-dioxin. J Biol Chem 280:12742-12746.
    • (2005) J Biol Chem , vol.280 , pp. 12742-12746
    • Thomae, T.L.1    Stevens, E.A.2    Bradfield, C.A.3
  • 53
    • 0017621954 scopus 로고
    • In vitro development of palatal tissues from embryonic mice. II. Tissue isolation and recombination studies
    • Tyler MS, Koch WE. 1977a. In vitro development of palatal tissues from embryonic mice. II. Tissue isolation and recombination studies. J Embryol Exp Morphol 38:19-36.
    • (1977) J Embryol Exp Morphol , vol.38 , pp. 19-36
    • Tyler, M.S.1    Koch, W.E.2
  • 54
    • 0017621959 scopus 로고
    • In vitro development of palatal tissues from embryonic mice. III. Interactions between palatal epithelium and heterotypic oral mesenchyme
    • Tyler MS, Koch WE. 1977b. In vitro development of palatal tissues from embryonic mice. III. Interactions between palatal epithelium and heterotypic oral mesenchyme. J Embryol Exp Morphol 38:37-48.
    • (1977) J Embryol Exp Morphol , vol.38 , pp. 37-48
    • Tyler, M.S.1    Koch, W.E.2
  • 55
    • 0018911142 scopus 로고
    • Effect of epidermal growth factor on secondary palatal epithelium in vitro: Tissue isolation and recombination studies
    • Tyler MS, Pratt RM. 1980. Effect of epidermal growth factor on secondary palatal epithelium in vitro: tissue isolation and recombination studies. J Embryol Exp Morphol 58:93-106.
    • (1980) J Embryol Exp Morphol , vol.58 , pp. 93-106
    • Tyler, M.S.1    Pratt, R.M.2
  • 56
    • 0014145757 scopus 로고
    • Palatal fusion in vitro in the mouse
    • Vargas VI. 1967. Palatal fusion in vitro in the mouse. Arch Oral Biol 12:1283-1288.
    • (1967) Arch Oral Biol , vol.12 , pp. 1283-1288
    • Vargas, V.I.1
  • 57
    • 0013569751 scopus 로고
    • Effects of hypervitaminosis A on palate development in two strains of mice
    • Walker BE, Crain Jr B. 1960. Effects of hypervitaminosis A on palate development in two strains of mice. Am J Anat 107:49-58.
    • (1960) Am J Anat , vol.107 , pp. 49-58
    • Walker, B.E.1    Crain Jr., B.2
  • 58
    • 0000701329 scopus 로고
    • Closure of the secondary palate in three strains of mice
    • Walker BE, Fraser FC. 1956. Closure of the secondary palate in three strains of mice. J Embryol Exp Morph 4:176-189.
    • (1956) J Embryol Exp Morph , vol.4 , pp. 176-189
    • Walker, B.E.1    Fraser, F.C.2
  • 59
    • 0007543158 scopus 로고
    • The embryology of cortisone-induced cleft palate
    • Walker BE, Fraser FC. 1957. The embryology of cortisone-induced cleft palate. J Embryol Exp Morph 5:201-209.
    • (1957) J Embryol Exp Morph , vol.5 , pp. 201-209
    • Walker, B.E.1    Fraser, F.C.2
  • 60
    • 0015849923 scopus 로고
    • Alterations in epithelial surface of a/Jax mouse palatal shelves prior to and during palatal fusion: A scanning electron microscopic study
    • Waterman RE, Ross LM, Meller SM. 1973. Alterations in epithelial surface of A/Jax mouse palatal shelves prior to and during palatal fusion: a scanning electron microscopic study. Anat Rec 176:361-376.
    • (1973) Anat Rec , vol.176 , pp. 361-376
    • Waterman, R.E.1    Ross, L.M.2    Meller, S.M.3
  • 61
    • 0043063075 scopus 로고    scopus 로고
    • Role of ERK1/2 signaling during EGF-induced inhibition of palatal fusion
    • Yamamoto T, Cui XM, Shuler CF. 2003. Role of ERK1/2 signaling during EGF-induced inhibition of palatal fusion. Dev Biol 260:512-521.
    • (2003) Dev Biol , vol.260 , pp. 512-521
    • Yamamoto, T.1    Cui, X.M.2    Shuler, C.F.3


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