Short-term pregnancy hormone treatment of N-methyl-N-nitrosourea-induced mammary carcinogenesis in relation to fatty acid composition of serum phospholipids in female Lewis rats

In Vivo

Volumn 24, Issue 4, 2010, Pages 553-560

  Lai, Yen Chang ^a   Hamazaki, Kei ^b   Yoshizawa, Katsuhiko ^a   Kawanaka, Ayako ^a   Kuwata, Maki ^a   Kanematsu, Sayaka ^a   Hamazaki, Tomohito ^b   Takada, Hideho ^a   Tsubura, Airo ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Fatty acid; Mammary cancer; Oestrogen; Progesterone; Rat

Indexed keywords

DOCOSAHEXAENOIC ACID; ESTROGEN; FATTY ACID; METHYLNITROSOUREA; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHOLIPID; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INHIBITION; CAPILLARY GAS CHROMATOGRAPHY; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; NONHUMAN; RAT; TUMOR VOLUME;

EID: 77955860773     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. MacMahon B, Cole P and Brown J: Etiology of human breast cancer: a review. J Natl Cancer Inst 50: 21-42, 1973.
2. Trichopoulos D, Hsieh CC, MacMahon B, Lin TM, Lowe CR, Mirra AP, Ravnihar B, Salber EJ, Valaoras VG and Yuasa S: Age at any birth and breast cancer risk. Int J Cancer 31: 701-704, 1983. (Pubitemid 13060771)
3. Nagata C, Hu YH and Shimizu H: Effects of menstrual and reproductive factors on the risk of breast cancer: meta-analysis of the case-control studies in Japan. Jpn J Cancer Res 86: 910-915, 1995.
4. Chie WC, Hsieh C, Newcomb PA, Longnecker MP, Mittendorf R, Greenberg ER, Clapp RW, Burke KP, Titus-Ernstoff L, Trentham-Dietz A and MacMahon B: Age at any full-term pregnancy and breast cancer risk. Am J Epidemiol 151: 715-722, 2000.
5. Merrill RM, Fugal S, Novilla LB and Raphael MC: Cancer risk associated with early and late maternal age at first birth. Gynecol Oncol 96: 583-593, 2005.
6. Yang J, Yoshizawa K, Nandi S and Tsubura A: Protective effects of pregnancy and lactation against N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 20: 623-628, 1999. (Pubitemid 29151298)
7. Nandi S, Guzman RC, Thordarson G and Rajkumar L: Estrogen can prevent breast cancer by mimicking the protective effect of pregnancy. In: Hormonal Carcinogenesis IV. Li JJ, Li SA and Llombart-Bosch A (eds.). New York, Springer, pp. 165-179, 2005.
8. Medina D, Kittrell FS, Tsimelzon A and Fuqua SA: Inhibition of mammary tumorigenesis by estrogen and progesterone in genetically engineered mice. Ernst Schering Found Symp Proc 1: 109-126, 2007.
9. Tsubura A, Uehara N, Matsuoka Y, Yoshizawa K and Yuri T: Estrogen and progesterone treatment mimicking pregnancy for protection from breast cancer. In Vivo 22: 191-201, 2008.
10. Yuri T, Tsukamoto R, Uehara N, Matsuoka Y and Tsubura A: Effects of different durations of estrogen and progesterone treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats. In Vivo 20: 829-836, 2006. (Pubitemid 46061586)
11. Tsukamoto R, Mikami T, Miki K, Uehara N, Yuri T, Matsuoka Y, Okazaki K and Tsubura A: N-Methyl-N-nitrosourea-induced mammary carcinogenesis is promoted by short-term treatment with estrogen and progesterone mimicking pregnancy in aged female Lewis rats. Oncol Rep 18: 337-342, 2007.
12. Russo IH and Russo J: Mammary gland neoplasia in long-term rodent studies. Environ Health Perspect 104: 938-967, 1996.
13. Uehara N, Unami A, Kiyozuka Y, Shikata N, Oishi Y and Tsubura A: Parous mammary glands exhibit distinct alterations in gene expression and proliferation responsiveness to carcinogenic stimuli in Lewis rats. Oncol Rep 15: 903-911, 2006.
14. Ginger MR, Gonzalez-Rimbau MF, Gay JP and Rosen JM: Persistent changes in gene expression induced by estrogen and progesterone in the rat mammary gland. Mol Endocrinol 15: 1993-2009, 2001.
15. D'Cruz CM, Moody SE, Master SR, Hartman JL, Keiper EA, Imielinski MB, Cox JD, Wang JY, Ha SI, Keister BA and Chodosh LA: Persistent parity-induced changes in growth factors, TGF-beta3, and differentiation in the rodent mammary gland. Mol Endocrinol 16: 2034-2051, 2002.
16. Blakely CM, Stoddard AJ, Belka GK, Dugan KD, Notarfrancesco KL, Moody SE, D'Cruz CM and Chodosh LA: Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy. Cancer Res 66: 6421-6431, 2006.
17. Matsuoka Y, Fukamachi K, Uehara N, Tsuda H and Tsubura A: Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis. Cancer Sci 99: 309-315, 2008.
18. Abrams TJ, Guzman RC, Swanson SM, Thordarson G, Talamantes F and Nandi S: Changes in the parous rat mammary gland environment are involved in parity-associated protection against mammary carcinogenesis. Anticancer Res 18: 4115-4121, 1998.
19. Tannenbaum A and Silverstone H: Nutrition in relation to cancer. Adv Cancer Res 1: 451-601, 1953.
20. Senzaki H, Iwamoto S, Ogura E, Kiyozuka Y, Arita S, Kurebayashi J, Takada H, Hioki K and Tsubura A: Dietary effects of fatty acids on growth and metastasis of KPL-1 human breast cancer cells in vivo and in vitro. Anticancer Res 18: 1621-1627, 1998. (Pubitemid 28342570)
21. Yuri T, Danbara N, Tsujita-Kyutoku M, Fukunaga K, Takada H, Inoue Y, Hada T and Tsubura A: Dietary docosahexaenoic acid suppresses N-methyl-N- nitrosourea-induced mammary carcinogenesis in rats more effectively than eicosapentaenoic acid. Nutr Cancer 45: 211-217, 2003.
22. Saadatian-Elahi M, Toniolo P, Ferrari P, Goudable J, Akhmedkhanov A, Zeleniuch-Jacquotte A and Riboli E: Serum fatty acids and risk of breast cancer in a nested case-control study of the New York University Women's Health Study. Cancer Epidemiol Biomarkers Prev 11: 1353-1360, 2002.
23. Zeleniuch-Jacquotte A, Chajès V, Van Kappel AL, Riboli E and Toniolo P: Reliability of fatty acid composition in human serum phospholipids. Eur J Clin Nutr 54: 367-372, 2000.
24. Otto SJ, van Houwelingen AC, Badart-Smook A and Hornstra G: Changes in the maternal essential fatty acid profile during early pregnancy and the relation of the profile to diet. Am J Clin Nutr 73: 302-307, 2001. (Pubitemid 32109860)
25. De Vriese SR, Dhont M and Christophe AB: FA composition of cholesteryl esters and phospholipids in maternal plasma during pregnancy and at delivery and in cord plasma at birth. Lipids 38: 1-7, 2003.
26. Bligh EG and Dyer WJ: Rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917, 1959.
27. Lai YC, Yuri T, Uehara N, Matsuoka Y, Kanematu S and Tsubura A: Biphasic effect of short-term pregnancy hormone treatment on N-methyl-N-nitrosourea- induced mammary carcinogenesis in young and old rats. Mol Med Rep 2: 213-220, 2009.
28. Tokunaga M, Land CE, Yamamoto T, Asano M, Tokuoka S, Ezaki H and Nishimori I: Incidence of female breast cancer among atomic bomb survivors, Hiroshima and Nagasaki, 1950-1980. Radiat Res 112: 243-272, 1987.
29. Thompson TA, Haag JD and Gould MN: Ras gene mutations are absent in NMU-induced mammary carcinomas from aging rats. Carcinogenesis 21: 1917-1922, 2000.
30. Ariazi JL, Haag JD, Lindstrom MJ and Gould MN: Mammary glands of sexually immature rats are more susceptible than those of mature rats to the carcinogenic, lethal, and mutagenic effects of N-nitroso-N-methylurea. Mol Carcinog 43: 155-164, 2005.
31. Chajès V, Hultén K, Van Kappel AL, Winkvist A, Kaaks R, Hallmans G, Lenner P and Riboli E: Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden. Int J Cancer 83: 585-590, 1999. (Pubitemid 29508033)
32. Okuyama H, Kobayashi T and Watanabe S: Dietary fatty acids the N-6/N-3 balance and chronic elderly diseases. Excess linoleic acid and relative n-3 deficiency syndrome seen in Japan. Prog Lipid Res 35: 409-457, 1996.
33. Wei N, Wang B, Zhang QY, Mi MT, Zhu JD, Yu XP, Yuan JL, Chen K, Wang J and Chang H: Effects of different dietary fatty acids on the fatty acid compositions and the expression of lipid metabolic-related genes in mammary tumor tissues of rats. Nutr Cancer 60: 810-825, 2008.
34. Al MD, Badart-Smook A, von Houwelingen AC, Hasaart TH and Hornstra G: Fat intake of women during normal pregnancy: relationship with maternal and neonatal essential fatty acid status. J Am Coll Nutr 15: 49-55, 1996.
35. Liu YE, Pu W, Wang J, Kang JX and Shi YE: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids. FEBS J 274: 3351-3362, 2007. (Pubitemid 47024970)
36. Maillard V, Bougnoux P, Ferrari P, Jourdan ML, Pinault M, Lavillonnière F, Body G, Le Floch O and Chajès V: n-3 and n-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France. Int J Cancer 98: 78-83, 2002.
37. Zhu ZR, Agren J, Männistö S, Pietinen P, Eskelinen M, Syrjänen K and Uusitupa M: Fatty acid composition of breast adipose tissue in breast cancer patients and in patients with benign breast disease. Nutr Cancer 24: 151-160, 1995.
38. Giltay EJ, Gooren LJ, Toorians AW, Katan MB and Zock PL: Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects. Am J Clin Nutr 80: 1167-1174, 2004.
39. Levant B, Radel JD and Carlson SE: Reduced brain DHA content after a single reproductive cycle in female rats fed a diet deficient in n-3 polyunsaturated fatty acids. Biol Psychiatry 60: 987-990, 2006. (Pubitemid 44584204)
40. Barceló-Coblijn G, Högyes E, Kitajka K, Puskás LG, Zvara A, Hackler L Jr, Nyakas C, Penke Z and Farkas T: Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipids. Proc Natl Acad Sci USA 100: 11321-11326, 2003. (Pubitemid 37205933)