In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery

European Journal of Pharmaceutical Sciences

Volumn 41, Issue 2, 2010, Pages 360-368

  Gordon, Sarah ^a   Teichmann, Elena ^a   Young, Katherine ^a   Finnie, Kim ^b   Rades, Thomas ^a   Hook, Sarah ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b CeramiSphere Pty Ltd   (Australia)

Author keywords

Chitosan; Immune response; Particulate sustained release vaccine delivery system; Silica nanoparticles; Thermosensitive hydrogel

Indexed keywords

ANTIGEN; CHITOSAN; NANOPARTICLE; OVALBUMIN; PROTEIN; QUIL A; SILICON DIOXIDE; VACCINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ELECTRON MICROSCOPY; FEMALE; HEAT SENSITIVITY; HUMORAL IMMUNITY; HYDROGEL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; ZETA POTENTIAL;

ANIMALS; CHITOSAN; FEMALE; HYDROGELS; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; SILICON DIOXIDE; VACCINES;

EID: 77955841465     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2010.07.004     Document Type: Article

References (42)

1. Barbé C., Bartlett J., Kong L., Finnie K., Lin H.Q., Larkin M., Calleja S., Bush A., Calleja G. Silica particles: a novel drug-delivery system. Adv. Mater. 2004, 16:1959-1966.
2. Barbé C.J., Kong L., Finnie K.S., Calleja S., Hanna J.V., Drabarek E., Cassidy D.T., Blackford M.G. Sol-gel matrices for controlled release: from macro to nano using emulsion polymerisation. J. Sol-Gel Sci. Technol. 2008, 46:393-409.
3. Barnden M.J., Allison J., Heath W.R., Carbone F.R. Defective TCR expression in transgenic mice constructed using cDNA-based a- and b-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 1998, 76:34-40.
4. Bramwell V.W., Perrie Y. The rational design of vaccines. DDT 2005, 10:1527-1534.
5. Bush A.J., Beyer R., Trautman R., Barbé C.J., Bartlett J.R. Ceramic micro-particles synthesised using emulsion and sol-gel technology: an investigation into the controlled release of encapsulants and the tailoring of micro-particle size. J. Sol-Gel Sci. Technol. 2004, 32:85-90.
6. Chenite A., Chaput C., Wang D., Combes C., Buschmann M.D., Hoemann C.D., Leroux J.C., Atkinson B.L., Binette F., Selmani A. Novel injectable neutral solutions of chitosan form biodegradable gels in situ. Biomaterials 2000, 21:2155-2161.
7. Cho J., Heuzey M.-C., Begin A., Carreau P.J. Physical gelation of chitosan in the presence of ß-glycerophosphate: the effect of temperature. Biomacromolecules 2005, 6:3267-3275.
8. Cho W.-S., Choi M., Han B.S., Cho M., Oh J., Park K., Kim S.J., Kim S.H., Jeong J. Inflammatory mediators induced by intratracheal instillation of ultrafine amorphous silica particles. Toxicol. Lett. 2007, 175:24-33.
9. Cox J.C., Coulter A.R. Adjuvants-a classification and review of their modes of action. Vaccine 1997, 15:248-256.
10. Das A., Das N., Naskar M.K., Kundu D., Chatterjee M., Maiti H.S. Influence of process parameters on the formation of silicalite-1 zeolite particles. Ceram. Int. 2009, 35:1799-1806.
11. El-Barghouthi M., Eftaiha A.a., Rashid I., Al-Remawi M., Badwan A. A novel superdisintegrating agent made from physically modified chitosan with silicon dioxide. Drug Dev. Ind. Pharm. 2008, 34:373-383.
12. Finnie K., Kong L., Jacques D., Lin H.-Q., McNiven S., Calleja S., Gorissen E., Barbé C. Encapsulation and controlled release from silica particles. Chem. Aust. 2005, 72:13-15.
13. Finnie K.S., Jacques D.A., McGann M.J., Blackford M.G., Barbé C.J. Encapsulation and controlled release of biomolecules from silica microparticles. J. Mater. Chem. 2006, 16:4494-4498.
14. Finnie K.S., Bartlett J.R., Barbé C.J.A., Kong L. Formation of silica nanoparticles in microemulsions. Langmuir 2007, 23:3017-3024.
15. Finnie K.S., Waller D.J., Perret F.L., Krause-Heuer A.M., Lin H.Q., Hanna J.V., Barbé C.J. Biodegradability of sol-gel silica microparticles for drug delivery. J. Sol-Gel Sci. Technol. 2009, 49:12-18.
16. Foged C., Brodin B., Frokjaer S., Sundblad A. Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int. J. Pharm. 2005, 298:315-322.
17. Foucras G., Gapin L., Coureau C., Kanellopoulos J.M., Guéry J.-C. Interleukin 4-producing CD4 T cells arise from different precursors depending on the conditions of antigen exposure in vivo. J. Exp. Med. 2000, 191:683-694.
18. Galindo-Rodriguez S., Allémann E., Fessi H., Doelker E. Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion, and nanoprecipitation methods. Pharm. Res. 2004, 21:1428-1439.
19. Gamvrellis A., Leong D., Hanley J.C., Xiang S.D., Mottram P., Plebanski M. Vaccines that facilitate antigen entry into dendritic cells. Immunol. Cell Biol. 2004, 82:506-516.
20. Ganguly S., Dash A.K. A novel in situ gel for sustained drug delivery and targeting. Int. J. Pharm. 2004, 276:83-92.
21. Gordon S., Saupe A., McBurney W., Rades T., Hook S. Comparison of chitosan nanoparticles and chitosan hydrogels for vaccine delivery. J. Pharm. Pharmacol. 2008, 60:1591-1600.
22. Guéry J.-C., Galbiati F., Smiroldo S., Adorini L. Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and b(2)-microglobulin-deficient BALB/c mice. J. Exp. Med. 1996, 183:485-497.
23. Guo X., Zheng D., Hu N. Enhancement of Au nanoparticles formed by in situ electrodeposition on direct electrochemistry of myoglobin loaded into layer-by-layer films of chitosan and silica nanoparticles. J. Phys. Chem. B 2008, 112:15513-15520.
24. Gupta R.K. Aluminum compounds as vaccine adjuvants. Adv. Drug Deliv. Rev. 1998, 32:155-172.
25. Ichinose T., Yoshida S., Sadakane K., Takano H., Yanagisawa R., Inoue K., Nishikawa M., Mori I., Kawazato H., Yasuda A., Shibamoto T. Effects of asian sand dust, arizona sand dust, amorphous silica and aluminum oxide on allergic inflammation in the murine lung. Inhal. Toxicol. 2008, 20:685-694.
26. Iler R.K. The Chemistry of Silica: Solubility, Polymerization, Colloid and Surface Properties, and Biochemistry 1979, Wiley Interscience, New York.
27. Jeong B., Kim S.W., Bae Y.H. Thermosensitive sol-gel reversible hydrogels. Adv. Drug Deliv. Rev. 2002, 54:37-51.
28. Kenney R.T., Edelman R. Survey of human-use adjuvants. Expert Rev. Vaccines 2003, 2:167-188.
29. Knopp D., Tang D., Niessner R. Review: bioanalytical applications of biomolecule-functionalized nanometer-sized doped silica particles. Anal. Chim. Acta 2009, 647:14-30.
30. Könnings S., Copland M.J., Davies N.M., Rades T. A method for the incorporation of ovalbumin into immune stimulating complexes prepared by the hydration method. Int. J. Pharm. 2002, 241:385-389.
31. Köping-Höggård M., Tubulekas I., Guan H., Edwards K., Nilsson M., Vårum K., Artursson P. Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Ther. 2001, 8:1108-1121.
32. Krauel K., Davies N.M., Hook S., Rades T. Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization. J. Control. Release 2005, 106:76-87.
33. Lofthouse S. Immunological aspects of controlled antigen delivery. Adv. Drug Deliv. Rev. 2002, 54:863-870.
34. McBurney W.T., Lendemans D.G., Myschik J., Hennessy T., Rades T., Hook S. In vivo activity of cationic immune stimulating complexes (PLUSCOMs). Vaccine 2008, 26:4549-4556.
35. Myschik J., McBurney W.T., Hennessy T., Phipps-Green A., Rades T., Hook S. Immunostimulatory biodegradable implants containing the adjuvant Quil-A-part II: in vivo evaluation. J. Drug Target. 2008, 16:224-232.
36. Pashine A., Valiante N.M., Ulmer J.B. Targeting the innate immune response with improved vaccine adjuvants. Nat. Med. 2005, 11:63-68.
37. Pham K.N., Fullston D., Sagoe-Crentsil K. Surface modification for stability of nano-sized silica colloids. J. Colloid Interf. Sci. 2007, 315:123-127.
38. Qin C., Gao J., Wang L., Zeng L., Liu Y. Safety evaluation of short-term exposure to chitooligomers from enzymic preparation. Food Chem. Toxicol. 2006, 44:855-861.
39. Ruel-Gariépy E., Leroux J.-C. In situ-forming hydrogels-review of temperature-sensitive systems. Eur. J. Pharm. Biopharm. 2004, 58:409-426.
40. Storni T., Kündig T.M., Senti G., Johansen P. Immunity in response to particulate antigen-delivery systems. Adv. Drug Deliv. Rev. 2005, 57:333-355.
41. Tao Liang M., Davies N.M., Blanchfield J.T., Toth I. Particulate systems as adjuvants and carriers for peptide and protein antigens. Curr. Drug Deliv. 2006, 3:379-388.
42. Zhao Z., Leong K.W. Controlled delivery of antigens and adjuvants in vaccine development. J. Pharm. Sci. 1996, 85:1261-1270.