Probiotics for allergic diseases: Realities and myths

Pediatric Allergy and Immunology

Volumn 21, Issue 6, 2010, Pages 900-919

  Yao, Tsung Chieh ^a,b   Chang, Chee Jen ^c,d   Hsu, Yi Hsien ^d   Huang, Jing Long ^a,b  

^a CHANG GUNG CHILDREN S HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

allergic disease; allergic rhinitis; allergy prevention; asthma; Lactobacillus; probiotics

Indexed keywords

CORTICOSTEROID; PROBIOTIC AGENT;

ACUPUNCTURE; ALLERGIC ASTHMA; ALLERGIC RHINITIS; ALLERGY; ASTHMA; ATOPIC DERMATITIS; BACTERIAL STRAIN; BIFIDOBACTERIUM ANIMALIS; BRONCHITIS; CHILD; CLINICAL TRIAL; ECZEMA; EVIDENCE BASED MEDICINE; HUMAN; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS RHAMNOSUS; PRIORITY JOURNAL; REVIEW; SUPPLEMENTATION;

ANIMALS; CHILD; EVIDENCE-BASED MEDICINE; HUMANS; HYPERSENSITIVITY; PROBIOTICS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 77955837989     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2009.00955.x     Document Type: Review

References (66)

1. Asher MI, Montefort S, Björkstén B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phases one and three repeat multicountry cross-sectional surveys. Lancet 2006 : 368 : 733 43.
2. Reid G, Zalai C, Gardiner G. Urogenital lactobacilli probiotics, reliability, and regulatory issues. J Dairy Sci 2001 : 84 : E164 9.
3. Metchnikoff E. The Prolongation of Life.
4. Stark PL, Lee A. The microbial ecology of the large bowel of breast-fed and formula-fed infants during the first year of life. J Med Microbiol 1982 : 15 : 189 203.
5. Cebra JJ. Influences of microbiota on intestinal immune system development. Am J Clin Nutr 1999 : 69 : 1046S 51S.
6. Holzapfel WH, Haberer P, Snel J, Schillinger U, Huis in't Veld JH. Overview of gut flora and probiotics. Int J Food Microbiol 1998 : 41 : 85 101.
7. FAOWHO. Guidelines for the evaluation of probiotics in food. 2002. Available at: http://www.who.int/foodsafety/publications/fs-management/ probiotics2/en/index.html (accessed 28 September 2009).
8. Vanderhoof JA, Young RJ. Pediatric applications of probiotics. Gastroenterol Clin North Am 2005 : 34 : 451 6.
9. Cabana MD, Shane AL, Chao C, Oliva-Hemker M. Probiotics in primary care pediatrics. Clin Pediatr 2006 : 45 : 405 10.
10. Strachan DP. Hay fever, hygiene and household size. Br Med J 1989 : 299 : 1259 60.
11. Contractor NV, Bassiri H, Reya T, et al. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J Immunol 1998 : 160 : 385 94.
12. Björkstén B, Naaber P, Sepp E, Mikelsaar M. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin Exp Allergy 1999 : 29 : 342 6.
13. Watanabe S, Narisawa Y, Arase S, et al. Differences in fecal microflora between patients with atopic dermatitis and healthy control subjects. J Allergy Clin Immunol 2003 : 111 : 587 91.
14. Kalliomäki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J Allergy Clin Immunol 2001 : 107 : 129 34.
15. Björkstén B, Sepp E, Julge K, Voor T, Mikelsaar M. Allergy development and the intestinal microflora during the first year of life. J Allergy Clin Immunol 2001 : 108 : 516 20. (Pubitemid 32978019)
16. Murray CS, Tannock GW, Simon MA, et al. Fecal microbiota in sensitized wheezy and non-sensitized non-wheezy children: a nested case-control study. Clin Exp Allergy 2005 : 35 : 741 5.
17. Kalliomäki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet 2001 : 357 : 1076 9.
18. Rautava S, Kalliomäki M, Isolauri E. Probiotics during pregnancy and breast-feeding might confer immunomodulatory protection against atopic disease in the infant. J Allergy Clin Immunol 2002 : 109 : 119 21.
19. Kalliomäki M, Salminen S, Poussa T, Arvilommi H, Isolauri E. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet 2003 : 361 : 1869 71.
20. Kalliomäki M, Salminen S, Poussa T, Isolauri E. Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial. J Allergy Clin Immunol 2007 : 119 : 1019 21.
21. Rautava S, Arvilommi H, Isolauri E. Specific probiotics in enhancing maturation of IgA responses in formula-fed infants. Pediatr Res 2006 : 60 : 221 4.
22. Kukkonen K, Savilahti E, Haahtela T, et al. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2007 : 119 : 192 8.
23. Taylor AL, Dunstan JA, Prescott SL. Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trial. J Allergy Clin Immunol 2007 : 119 : 184 91.
24. Prescott SL, Wiltschut J, Taylor A, et al. Early markers of allergic disease in a primary prevention study using probiotics: 2.5-year follow-up phase. Allergy 2008 : 63 : 1481 90.
25. Abrahamsson TR, Jakobsson T, Böttcher MF, et al. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol 2007 : 119 : 1174 80.
26. Kopp MV, Hennemuth I, Heinzmann A, Urbanek R. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation. Pediatrics 2008 : 121 : e850 6.
27. Huurre A, Laitinen K, Rautava S, Korkeamäki M, Isolauri E. Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study. Clin Exp Allergy 2008 : 38 : 1342 8.
28. Wickens K, Black PN, Stanley TV, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clin Immunol 2008 : 122 : 788 94.
29. Wheeler JG, Shema SJ, Bogle ML, et al. Immune and clinical impact of Lactobacillus acidophilus on asthma. Ann Allergy Asthma Immunol 1997 : 79 : 229 33.
30. Stockert K, Schneider B, Porenta G, Rath R, Nissel H, Eichler I. Laser acupuncture and probiotics in school age children with asthma: a randomized, placebo-controlled pilot study of therapy guided by principles of Traditional Chinese Medicine. Pediatr Allergy Immunol 2007 : 18 : 160 6.
31. Giovannini M, Agostoni C, Riva E, et al. A randomized prospective double blind controlled trial on effects of long-term consumption of fermented milk containing Lactobacillus casei in pre-school children with allergic asthma andor rhinitis. Pediatr Res 2007 : 62 : 215 20.
32. Trapp CL, Chang CC, Halpern GM, Keen CL, Gershwin ME. The influence of chronic yogurt consumption on populations of young and elderly adults. Int J Immunother 1993 : 9 : 53 64.
33. Van de Water J, Keen CL, Gershwin ME. The influence of chronic yogurt consumption on immunity. J Nutr 1999 : 129 (Suppl. 1492S 5S.
34. Helin T, Haahtela S, Haahtela T. No effect of oral treatment with an intestinal bacterial strain, Lactobacillus rhamnosus (ATCC 53103), on birch-pollen allergy: a placebo-controlled double-blind study. Allergy 2002 : 57 : 243 6.
35. Aldinucci C, Bellussi L, Monciatti G, et al. Effects of dietary yoghurt on immunological and clinical parameters of rhinopathic patients. Eur J Clin Nutr 2002 : 56 : 1155 61.
36. Wang MF, Lin HC, Wang YY, Hsu CH. Treatment of perennial allergic rhinitis with lactic acid bacteria. Pediatr Allergy Immunol 2004 : 15 : 152 8.
37. Peng GC, Hsu CH. The efficacy and safety of heat-killed Lactobacillus paracasei for treatment of perennial allergic rhinitis induced by house-dust mite. Pediatr Allergy Immunol 2005 : 16 : 433 8.
38. Ishida Y, Nakamura F, Kanzato H, et al. Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebo-controlled study. J Dairy Sci 2005 : 88 : 527 33.
39. Xiao JZ, Kondo S, Yanagisawa N, et al. Probiotics in the treatment of Japanese cedar pollinosis: a double-blind placebo-controlled trial. Clin Exp Allergy 2006 : 36 : 1425 35.
40. Xiao JZ, Kondo S, Yanagisawa N, et al. Effect of probiotic Bifidobacterium longum BB536 in relieving clinical symptoms and modulating plasma cytokine levels of Japanese cedar pollinosis during the pollen season. A randomized double-blind, placebo-controlled trial. J Investig Allergol Clin Immunol 2006 : 16 : 86 93.
41. Ishida Y, Nakamura F, Kanzato H, et al. Effect of milk fermented with Lactobacillus acidophilus strain L-92 on symptoms of Japanese cedar pollen allergy: a randomized placebo-controlled trial. Biosci Biotechnol Biochem 2005 : 69 : 1652 60.
42. Tamura M, Shikina T, Morihana T, et al. Effects of probiotics on allergic rhinitis induced by Japanese cedar pollen: randomized double-blind, placebo-controlled clinical trial. Int Arch Allergy Immunol 2007 : 143 : 75 82.
43. Boyle RJ, Tang ML. The role of probiotics in the management of allergic disease. Clin Exp Allergy 2006 : 36 : 568 76.
44. Majamaa H, Isolauri E. Probiotics: a novel approach in the management of food allergy. J Allergy Clin Immunol 1997 : 99 : 179 85.
45. Isolauri E, Arvola T, Sütas Y, Moilanen E, Salminen S. Probiotics in the management of atopic eczema. Clin Exp Allergy 2000 : 30 : 1604 10.
46. Kirjavainen PV, Salminen SJ, Isolauri E. Probiotic bacteria in the management of atopic disease: underscoring the importance of viability. J Pediatr Gastroenterol Nutr 2003 : 36 : 223 7.
47. Rosenfeldt V, Benfeldt E, Nielsen SD, et al. Effect of probiotic Lactobacillus strains in children with atopic dermatitis. J Allergy Clin Immunol 2003 : 111 : 389 95.
48. Viljanen M, Savilahti E, Haahtela T, et al. Probiotics in the treatment of atopic eczemadermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy 2005 : 60 : 494 500.
49. Taniuchi S, Hattori K, Yamamoto A, et al. Administration of Bifidobacterium to infants with atopic dermatitis: changes in fecal microflora and clinical symptoms. J Appl Res 2005 : 5 : 387 96.
50. Weston S, Halbert A, Richmond P, Prescott SL. Effects of probiotics on atopic dermatitis: a randomised controlled trial. Arch Dis Child 2005 : 90 : 892 7.
51. Sistek D, Kelly R, Wickens K, Stanley T, Fitzharris P, Crane J. Is the effect of probiotics on atopic dermatitis confined to food sensitized children? Clin Exp Allergy 2006 : 36 : 629 33.
52. Passeron T, Lacour JP, Fontas E, Ortonne JP. Prebiotics and synbiotics: two promising approaches for the treatment of atopic dermatitis in children above 2 years. Allergy 2006 : 61 : 431 7.
53. Brouwer ML, Wolt-Plompen SA, Dubois AE, et al. No effects of probiotics on atopic dermatitis in infancy: a randomized placebo-controlled trial. Clin Exp Allergy 2006 : 36 : 899 906.
54. Fölster-Holst R, Müller F, Schnopp N, et al. Prospective, randomized controlled trial on Lactobacillus rhamnosus in infants with moderate to severe atopic dermatitis. Br J Dermatol 2006 : 155 : 1256 61.
55. Grüber C, Wendt M, Sulser C, et al. Randomized, placebo-controlled trial of Lactobacillus rhamnosus GG as treatment of atopic dermatitis in infancy. Allergy 2007 : 62 : 1270 6.
56. Matsumoto M, Aranami A, Ishige A, Watanabe K, Benno Y. LKM512 yogurt consumption improves the intestinal environment and induces the T-helper type 1 cytokine in adult patients with intractable atopic dermatitis. Clin Exp Allergy 2007 : 37 : 358 70.
57. Roessler A, Friedrich U, Vogelsang H, et al. The immune system in healthy adults and patients with atopic dermatitis seems to be affected differently by a probiotic intervention. Clin Exp Allergy 2008 : 38 : 93 102.
58. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993 : 186 : 23 31.
59. Isolauri E, Salminen S, Ouwehand AC. Probiotics. Best Pract Res Clin Gastroenterol 2004 : 18 : 299 313.
60. Boyle RJ, Robins-Browne RM, Tang ML. Probiotic use in clinical practice: what are the risks? Am J Clin Nutr 2006 : 83 : 1256 64.
61. Land MH, Rouster-Stevens K, Woods CR, Cannon ML, Cnota J, Shetty AK. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005 : 115 : 178 81.
62. De Groote MA, Frank DN, Dowell E, Glode MP, Pace NR. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005 : 24 : 278 80.
63. Kunz AN, Noel JM, Fairchok MP. Two cases of Lactobacillus bacteremia during probiotic treatment of short gut syndrome. J Pediatr Gastroenterol Nutr 2004 : 38 : 457 8.
64. Borriello SP, Hammes WP, Holzapfel W, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003 : 36 : 775 80.
65. Bäckhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. Host-bacterial mutualism in the human intestine. Science 2005 : 307 : 1915 20.
66. Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 1993 : 14 : 353 6.