Polyphenols of Camellia sinenesis decrease mortality, hepatic injury and generation of cytokines and reactive oxygen and nitrogen species after hemorrhage/resuscitation in rats

BMC Complementary and Alternative Medicine

Volumn 10, Issue , 2010, Pages

  Lehnert, Mark ^b   Lind, Henrik ^a,b   Zhong, Zhi ^a   Schoonhoven, Robert ^d   Marzi, Ingo ^b   Lemasters, John J ^a,c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b GOETHE UNIVERSITY   (Germany)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ALANINE AMINOTRANSFERASE; CATECHIN; EPICATECHIN; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; GALLOCATECHIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; RINGER LACTATE SOLUTION; TUMOR NECROSIS FACTOR ALPHA; 3-NITROTYROSINE; CYTOKINE; DRUG DERIVATIVE; FLAVONOID; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; TYROSINE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; FEMALE; HEMORRHAGIC SHOCK; IMMUNOHISTOCHEMISTRY; LIVER INJURY; MORTALITY; NONHUMAN; PROTEIN EXPRESSION; RAT; RESUSCITATION; SURVIVAL; TEA; WESTERN BLOTTING; ANIMAL; BLOOD; BLOOD TRANSFUSION; CHEMISTRY; LIPID PEROXIDATION; LIVER; LIVER DISEASE; METABOLISM; PHYTOTHERAPY; SPRAGUE DAWLEY RAT;

ALANINE TRANSAMINASE; ANIMALS; BLOOD TRANSFUSION; CAMELLIA SINENSIS; CYTOKINES; FEMALE; FLAVONOIDS; LIPID PEROXIDATION; LIVER; LIVER DISEASES; NITRIC OXIDE SYNTHASE TYPE II; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; RESUSCITATION; SHOCK, HEMORRHAGIC; TYROSINE;

EID: 77955829989     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-10-46     Document Type: Article

References (45)

1. Baue AE, Durham R, Faist E. Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle?. Shock 1998, 10:79-89. 10.1097/00024382-199808000-00001, 9721973.
2. Keel M, Trentz O. Pathophysiology of polytrauma. Injury 2005, 36:691-709. 10.1016/j.injury.2004.12.037, 15910820.
3. Heckbert SR, Vedder NB, Hoffman W, Winn RK, Hudson LD, Jurkovich GJ, Copass MK, Harlan JM, Rice CL, Maier RV. Outcome after hemorrhagic shock in trauma patients. J Trauma 1998, 45:545-549. 10.1097/00005373-199809000-00022, 9751548.
4. Akgur FM, Brown MF, Zibari GB, McDonald JC, Epstein CJ, Ross CR, Granger DN. Role of superoxide in hemorrhagic shock-induced P-selectin expression. Am J Physiol Heart Circ Physiol 2000, 279:H791-H797.
5. Cockerill GW, McDonald MC, Mota-Filipe H, Cuzzocrea S, Miller NE, Thiemermann C. High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock. FASEB J 2001, 15:1941-1952. 10.1096/fj.01-0075com, 11532974.
6. Hensley K, Robinson KA, Gabbita SP, Salsman S, Floyd RA. Reactive oxygen species, cell signaling, and cell injury. Free Radic Biol Med 2000, 28:1456-1462. 10.1016/S0891-5849(00)00252-5, 10927169.
7. Abdelrahman M, Mazzon E, Bauer M, Bauer I, Delbosc S, Cristol JP, Patel NS, Cuzzocrea S, Thiemermann C. Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock. Shock 2005, 23:107-114. 10.1097/01.shk.0000151028.15377.f7, 15665724.
8. Lehnert M, Arteel GE, Smutney OM, Conzelmann LO, Zhong Z, Thurman RG, Lemasters JJ. Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide. Shock 2003, 19:345-351. 10.1097/00024382-200304000-00009, 12688546.
9. Bauer C, Walcher F, Holanda M, Mertzlufft F, Larsen R, Marzi I. Antioxidative resuscitation solution prevents leukocyte adhesion in the liver after hemorrhagic shock. J Trauma 1999, 46:886-893. 10.1097/00005373-199905000-00019, 10338408.
10. Bahrami S, Yao YM, Leichtfried G, Redl H, Schlag G, Di Padova FE. Monoclonal antibody to endotoxin attenuates hemorrhage-induced lung injury and mortality in rats. Crit Care Med 1997, 25:1030-1036. 10.1097/00003246-199706000-00021, 9201057.
11. Serafini M, Ghiselli A, Ferro-Luzzi A. In vivo antioxidant effect of green and black tea in man. Eur J Clin Nutr 1996, 50:28-32.
12. Zhao BL, Li XJ, He RG, Cheng SJ, Xin WJ. Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals. Cell Biophys 1989, 14:175-185.
13. Zhong Z, Froh M, Connor HD, Li X, Conzelmann LO, Mason RP, Lemasters JJ, Thurman RG. Prevention of hepatic ischemia-reperfusion injury by green tea extract. Am J Physiol Gastrointest Liver Physiol 2002, 283:G957-G964.
14. Thring TS, Hili P, Naughton DP. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complement Altern Med 2009, 9:27. 10.1186/1472-6882-9-27, 2728709, 19653897.
15. Frei B, Higdon JV. Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J Nutr 2003, 133:3275S-3284S.
16. Cabrera C, Artacho R, Gimenez R. Beneficial effects of green tea--a review. J Am Coll Nutr 2006, 25:79-99.
17. Miller MJ, Angeles FM, Reuter BK, Bobrowski P, Sandoval M. Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis. BMC Complement Altern Med 2001, 1:11. 10.1186/1472-6882-1-11, 61450, 11749672.
18. Sutherland BA, Rahman RM, Appleton I. Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration. J Nutr Biochem 2006, 17:291-306. 10.1016/j.jnutbio.2005.10.005, 16443357.
19. Zhong Z, Connor HD, Froh M, Lind H, Bunzendahl H, Mason RP, Thurman RG, Lemasters JJ. Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats. Free Radic Biol Med 2004, 36:1248-1258. 10.1016/j.freeradbiomed.2004.02.012, 15110390.
20. Zhong Z, Connor HD, Froh M, Bunzendahl H, Lind H, Lehnert M, Mason RP, Thurman RG, Lemasters JJ. Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology 2005, 129:652-664.
21. Lehnert M, Uehara T, Bradford BU, Lind H, Zhong Z, Brenner DA, Marzi I, Lemasters JJ. Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation. Am J Physiol Gastrointest Liver Physiol 2006, 291:G456-G463. 10.1152/ajpgi.00480.2005, 16614372.
22. Gaddipati JP, Sundar SV, Calemine J, Seth P, Sidhu GS, Maheshwari RK. Differential regulation of cytokines and transcription factors in liver by curcumin following hemorrhage/resuscitation. Shock 2003, 19:150-156. 10.1097/00024382-200302000-00011, 12578124.
23. Toth B, Yokoyama Y, Schwacha MG, George RL, Rue LW, Bland KI, Chaudry IH. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. J Appl Physiol 2004, 97:2184-2189. 10.1152/japplphysiol.00499.2004, 15298985.
24. Zingarelli B, Squadrito F, Altavilla D, Calapai G, Di Rosa M, Caputi AP. Role of tumor necrosis factor-alpha in acute hypovolemic hemorrhagic shock in rats. Am J Physiol 1994, 266:H1512-H1515.
25. Zhong Z, Froh M, Lehnert M, Schoonhoven R, Yang L, Lind H, Lemasters JJ, Thurman RG. Polyphenols from Camellia sinensis Attenuate Experimental Cholestasis-Induced Liver Fibrosis in Rats. Am J Physiol Gastrointest Liver Physiol 2003, 285:G1004-G1013.
26. Szabo C, Billiar TR. Novel roles of nitric oxide in hemorrhagic shock. Shock 1999, 12:1-9. 10.1097/00024382-199907000-00001, 10468045.
27. Kan WH, Hsu JT, Schwacha MG, Choudhry MA, Raju R, Bland KI, Chaudry IH. Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury. J Appl Physiol 2008, 105:1076-1082. 10.1152/japplphysiol.90495.2008, 2576035, 18635878.
28. Collins JL, Vodovotz Y, Hierholzer C, Villavicencio RT, Liu S, Alber S, Gallo D, Stolz DB, Watkins SC, Godfrey A, et al. Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock. Shock 2003, 19:117-122. 10.1097/00024382-200302000-00005, 12578118.
29. Mauriz JL, Matilla B, Culebras JM, Gonzalez P, Gonzalez-Gallego J. Dietary glycine inhibits activation of nuclear factor kappa B and prevents liver injury in hemorrhagic shock in the rat. Free Radic Biol Med 2001, 31:1236-1244. 10.1016/S0891-5849(01)00716-X, 11705702.
30. Kentner R, Safar P, Behringer W, Wu X, Kagan VE, Tyurina YY, Henchir J, Ma L, Hsia CJ, Tisherman SA. Early antioxidant therapy with Tempol during hemorrhagic shock increases survival in rats. J Trauma 2002, 53:968-977. 10.1097/00005373-200211000-00025, 12435951.
31. Mota-Filipe H, McDonald MC, Cuzzocrea S, Thiemermann C. A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock. Shock 1999, 12:255-261. 10.1097/00024382-199910000-00002, 10509626.
32. Ruch RJ, Cheng SJ, Klaunig JE. Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis 1989, 10:1003-1008. 10.1093/carcin/10.6.1003, 2470525.
33. Guo Q, Zhao B, Li M, Shen S, Xin W. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1996, 1304:210-222.
34. Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988, 255:H1269-H1275.
35. Grisham MB, Granger DN, Lefer DJ. Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease. Free Radic Biol Med 1998, 25:404-433. 10.1016/S0891-5849(98)00094-X, 9741579.
36. Szabo C. The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock 1996, 6:79-88. 10.1097/00024382-199608000-00001, 8856840.
37. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990, 87:1620-1624. 10.1073/pnas.87.4.1620, 53527, 2154753.
38. Bahrami S, Yao YM, Leichtfried G, Redl H, Marzi I, Schlag G. Significance of TNF in hemorrhage-related hemodynamic alterations, organ injury, and mortality in rats. Am J Physiol 1997, 272:H2219-H2226.
39. Maier M, Strobele H, Voges J, Bauer C, Marzi I. Attenuation of leukocyte adhesion by recombinant TNF-binding protein after hemorrhagic shock in the rat. Shock 2003, 19:457-461. 10.1097/01.shk.0000056961.48384.f2, 12744490.
40. Sato H, Tanaka T, Kasai K, Kita T, Tanaka N. Role of p38 mitogen-activated protein kinase on renal dysfunction after hemorrhagic shock in rats. Shock 2005, 24:488-494. 10.1097/01.shk.0000176594.64626.7f, 16247337.
41. Coimbra R, Porcides R, Loomis W, Melbostad H, Lall R, Deree J, Wolf P, Hoyt DB. HSPTX protects against hemorrhagic shock resuscitation-induced tissue injury: an attractive alternative to Ringer's lactate. J Trauma 2006, 60:41-51. 10.1097/01.ta.0000197417.03460.0a, 16456435.
42. Yang S, Hu S, Hsieh YC, Choudhry MA, Rue LW, Bland KI, Chaudry IH. Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage. J Mol Cell Cardiol 2006, 40:570-579. 10.1016/j.yjmcc.2006.01.008, 16499925.
43. Meng ZH, Dyer K, Billiar TR, Tweardy DJ. Essential role for IL-6 in postresuscitation inflammation in hemorrhagic shock. Am J Physiol Cell Physiol 2001, 280:C343-C351.
44. Aderka D, Le JM, Vilcek J. IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J Immunol 1989, 143:3517-3523.
45. Yoshizawa K, Naruto M, Ida N. Injection time of interleukin-6 determines fatal outcome in experimental endotoxin shock. J Interferon Cytokine Res 1996, 16:995-1000.