SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes

BMC Medical Genetics

Volumn 11, Issue 1, 2010, Pages

  Jiang, Yi Der ^a   Chang, Yi Cheng ^a,b   Chiu, Yen Feng ^c   Chang, Tien Jyun ^a   Li, Hung Yuan ^a   Lin, Wen Hsing ^c   Yuan, Hsiang Yu ^d   Chen, Yuan Tsong ^d   Chuang, Lee Ming ^a,e  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 10; UNCLASSIFIED DRUG; SLC2A10 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; ARTERY DISEASE; ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PREDICTION; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; DIABETIC ANGIOPATHY; GENETICS; LONGITUDINAL STUDY; MIDDLE AGED; PERIPHERAL VASCULAR DISEASE; RISK;

AGED; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; FEMALE; GENOTYPE; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; HAPLOTYPES; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; ODDS RATIO; PERIPHERAL VASCULAR DISEASES; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK; RISK FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 77955804588     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-11-126     Document Type: Article

References (25)

1. Adler AI, Stevens RJ, Neil A, Stratton IM, Boulton AJ, Holman RR. UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes. Diabetes Care 2002, 25:894-899. 10.2337/diacare.25.5.894, 11978687.
2. Keen H, Clark C, Laakso M. Reducing the burden of diabetes: managing cardiovascular disease. Diabetes Metab Res Rev 1999, 15:186-196. 10.1002/(SICI)1520-7560(199905/06)15:3<186::AID-DMRR30>3.0.CO;2-5, 10441041.
3. Carmelli D, Fabsitz RR, Swan GE, Reed T, Miller B, Wolf PA. Contribution of genetic and environmental influences to ankle-brachial blood pressure index in the NHLBI Twin Study. National Heart, Lung, and Blood Institute. Am J Epidemiol 2000, 151:452-458.
4. Gudmundsson G, Matthiasson SE, Arason H, Johannsson H, Runarsson F, Bjarnason H, et al. Localization of a Gene for Peripheral Arterial Occlusive Disease to Chromosome 1p31. Am J Hum Genet 2002, 70:586-592. 10.1086/339251, 384938, 11833003.
5. Coucke PJ, Willaert A, Wessels MW, Callewaert B, Zoppi N, De Backer J, et al. Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome. Nat Genet 2006, 38:452-457. 10.1038/ng1764, 16550171.
6. Drera B, Guala A, Zoppi N, Gardella R, Franceschini P, Barlati S, et al. Two novel SLC2A10/GLUT10 mutations in a patient with arterial tortuosity syndrome. Am J Med Genet A 2007, 143:216-218.
7. Zaidi SH, Meyer S, Peltekova VD, Lindinger A, Teebi AS, Faiyaz-Ul-Haque M. A novel non-sense mutation in the SLC2A10 gene of an arterial tortuosity syndrome patient of Kurdish origin. Eur J Pediatr 2008,
8. Callewaert BL, Willaert A, Kerstjens-Frederikse WS, De Backer J, Devriendt K, Albrecht B, et al. Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families. Hum Mutat 2008, 29:150-158. 10.1002/humu.20623, 17935213.
9. Brownlee M. The Pathobiology of Diabetic Complications. A Unifying Mechanism. Diabetes 2005, 54:1615-1625. 10.2337/diabetes.54.6.1615, 15919781.
10. Ziyadeh FN. Mediators of Diabetic Renal Disease: The case for TGF-β as the major mediator. J Am Soc Nephrol 2004, 15:S55-S57. 10.1097/01.ASN.0000093460.24823.5B, 14684674.
11. Chiarelli F, Santilli F, Mohn A. Role of growth factors in the development of diabetic complications. Hormone Research 2000, 53:53-67. 10.1159/000023515, 10971090.
12. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1:diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998, 15:539-553. 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S, 9686693.
13. Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL, et al. ACC/AHA 2005 Guidelines for the Management of Patients With Peripheral Arterial Disease (Lower Extremity, Renal, Mesenteric, and Abdominal Aortic): Executive Summary A Collaborative Report From the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease) Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. J Am Coll Cardiol 2006, 47:1239-1312. 10.1016/j.jacc.2005.10.009, 16545667.
14. Lin WH, Chuang LM, Chen CH, Yeh JI, Hsieh PS, Cheng CH, et al. An association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in Taiwanese population. Diabetologia 2006, 49:1214-1221. 10.1007/s00125-006-0218-3, 16586067.
15. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265. 10.1093/bioinformatics/bth457, 15297300.
16. Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA. Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 2002, 70:425-434. 10.1086/338688, 384917, 11791212.
17. Mueckler M. Family of glucose-transporter genes. Implications for glucose homeostasis and diabetes. Diabetes 1990, 39:6-11. 10.2337/diabetes.39.1.6, 2210061.
18. Cheng CH, Kikuchi T, Chen YH, Sabbagha NG, Lee YC, Pan HJ, et al. Mutations in the SLC2A10 gene cause arterial abnormalities in mice. Cardiovasc Res 2008,
19. Andersen G, Rose CS, Hamid YH, Drivsholm T, Borch-Johnsen K, Pedersen O. Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationship to type 2 diabetes and intermediary traits. Diabetes 2003, 52:2445-2448. 10.2337/diabetes.52.9.2445, 12941788.
20. Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, et al. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 2005, 434:338-345. 10.1038/nature03441, 2923337, 15735639.
21. Chaturvedi N, Stevens LK, Fuller JH, Lee ET, Lu M. Risk factors, ethnic differences and mortality associated with lower-extremity gangrene and amputation in diabetes. The WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 2001, 44(Suppl 2):S65-71. 10.1007/PL00002941, 11587052.
22. Beks PJ, Mackaay AJ, de Neeling JN, de Vries H, Bouter LM, Heine RJ. Peripheral arterial disease in relation to glycemic level in an elderly Caucasian population: the Hoorn study. Diabetologia 1995, 38:86-96. 10.1007/BF02369357, 7744233.
23. Premalatha G, Shanthirani S, Deepa R, Markovitz J, Mohan V. Prevalence and risk factors of peripheral vascular disease in a selected south India population. Diabetes Care 2000, 23:1295-1300. 10.2337/diacare.23.9.1295, 10977021.
24. The International HapMap Consortium The International HapMap Project. Nature 2003, 426:789-796. 10.1038/nature02168, 14685227, The International HapMap Consortium.
25. Yang HC, Lin CH, Hsu CL, Hung SI, Wu JY, Pen WH, Chen YT, Fann CS. A comparison of major histocompatibility complex SNPs in Han Chinese residing in Taiwan and Caucasians. J Biomed Sci 2006, 13:489-98. 10.1007/s11373-006-9077-7, 16544196.