Essential genes from Arctic bacteria used to construct stable, temperature-sensitive bacterial vaccines

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 30, 2010, Pages 13456-13460

  Duplantis, Barry N ^a   Osusky, Milan ^a   Schmerk, Crystal L ^a   Ross, Darrell R ^a   Bosio, Catharine M ^b   Nano, Francis E ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Colwellia; Francisella; Mycobacterium; Psychrophile

Indexed keywords

BACTERIAL VACCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; DNA LIGASE (NAD);

ARCTIC; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM; ESSENTIAL GENE; FRANCISELLA TULARENSIS; GENE FUNCTION; GENE ISOLATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IMMUNITY; MAMMAL; MOLECULAR EVOLUTION; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PSYCHROPHILIC BACTERIUM; SALMONELLA ENTERICA; TEMPERATURE SENSITIVITY; TUBERCULOSIS; VACCINATION; ALTEROMONADACEAE; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CLASSIFICATION; CYTOLOGY; FEMALE; GENETIC ENGINEERING; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MACROPHAGE; MICROBIOLOGY; MOLECULAR GENETICS; MOUSE; PHYLOGENY; SEQUENCE HOMOLOGY; TEMPERATURE; TULAREMIA;

ALTEROMONADACEAE; AMINO ACID SEQUENCE; ANIMALS; ARCTIC REGIONS; BACTERIAL VACCINES; CELL LINE; DNA LIGASES; FEMALE; FRANCISELLA TULARENSIS; GENES, BACTERIAL; GENES, ESSENTIAL; GENETIC ENGINEERING; MACROPHAGES; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM SMEGMATIS; PHYLOGENY; SALMONELLA ENTERICA; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE; TULAREMIA;

EID: 77955795379     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004119107     Document Type: Article

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