Levels of elevated circulating endothelial cell decline after tumor resection in patients with pancreatic ductal adenocarcinoma

Anticancer Research

Volumn 30, Issue 7, 2010, Pages 2911-2917

  Sabbaghian, M Shirin ^a   Rothberger, Gary ^a   Alongi, Alexandra P ^a   Gagner, Jean Pierre ^a   Goldberg, Judith D ^a   Rolnitzky, Linda ^a   Chiriboga, Luis ^a   Hajdu, Cristina H ^a   Zagzag, David ^a,b   Basch, Ross ^a,b   Shamamian, Peter ^c,d  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Endothelial cells; Neovascularization; Pancreatic cancer; Placental growth factor

Indexed keywords

BIOLOGICAL MARKER; PLACENTAL GROWTH FACTOR; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER RECURRENCE; CANCER SURGERY; CELL COUNT; CELL ISOLATION; CELL LINEAGE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPATHOLOGY; DISEASE ASSOCIATION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MALE; NEOVASCULARIZATION (PATHOLOGY); PANCREAS ADENOCARCINOMA; PANCREAS CELL; PANCREAS DUCT; PANCREAS DUCT ADENOCARCINOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, PANCREATIC DUCTAL; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC NEOPLASMS; PREGNANCY PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77955783268     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Folkman J: Tumor angiogenesis: therapeutic implications. N Engl J Med 285(21): 1182-1186, 1971.
2. Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebeis M, Negrier S, Chevreau C, Solska E, Desai AA, Rolland F, Demkow T, Hutson TE, Gore M, Freeman S, Schwartz B, Shan M, Simantov R and Bukowski RM: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 356(2): 125-134, 2007. (Pubitemid 46089673)
3. Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin J, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R and Kabbinavar F: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350(23): 2335-2342, 2004.
4. Beerepoot LV, Mehra N, Vermaat JS, Zonnenberg BA, Gebbink MF and Voest EE: Increased levels of viable circulating endothelial cells are an indicator of progressive disease in cancer patients. Ann Oncol 15(1): 139-145, 2004. (Pubitemid 38139616)
5. Broll R, Erdmann H, Duchrow M, Oevermann E, Schwandner O, Markert U, Bruch HP and Windhövel U: Vascular endothelial growth factor (VEGF)-a valuable serum tumour marker in patients with colorectal cancer? Eur J Surg Oncol 27(1): 37-42, 2001.
6. Li B, Sharpe EE, Maupin AB, Teleron AA, Pyle AL, Carmeliet P and Young PP: VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization. FASEB J 20(9): 1495-1497, 2006.
7. Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, Kearne M, Magner M and Isner JM: Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 85(3): 221-228, 1999.
8. Shaw JP, Basch R and Shamamian P: Hematopoietic stem cells and endothelial cell precursors express Tie-2, CD31 and CD45. Blood Cells Mol Dis 32(1): 168-175, 2004. (Pubitemid 38147714)
9. Bertolini F, Shaked Y, Mancuso P and Kerbel RS: The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer 6(11): 835-845, 2006. (Pubitemid 44629895)
10. Mancuso P, Calleri A, Cassi C, Gobbi A, Capillo M, Pruneri G, Martinelli G and Bertolini F: Circulating endothelial cells as a novel marker of angiogenesis. Adv Exp Med Biol 522: 83-97, 2003. (Pubitemid 36570529)
11. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ and Thun MJ: Cancer statistics. CA Cancer J Clin 55(1): 10-30, 2005.
12. Kindler HL: Pancreatic cancer: an update. Curr Oncol Rep 9(3): 170-176, 2005.
13. Shi Q, Rafii S, Wu MH, Wijelath ES, Yu C, Ishida A, Fujita Y, Kothari S, Mohle R, Sauvage LR, Moore MA, Storb RF and Hammond WP: Evidence for circulating bone marrow-derived endothelial cells. Blood 92(2): 362-367, 1998.
14. Takahashi T, Kalka C, Masuda H, Chen D, Silver M, Kearney M, Magner M, Isner JM and Asahara T: Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 5(4): 434-438, 1999. (Pubitemid 29180584)
15. Korbling M, Reuben JM, Gao H, Lee BN, Harris DM, Cogdell D, Giralt SA, Khouri IF, Saliba RM, Champlin RE, Zhang W and Estrov Z: Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: a novel blood cell component for therapeutic vasculogenesis. Transfusion 46(10): 1795-1802, 2006.
16. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G and Isner JM: Isolation of putative progenitor endothelial cells for angiogenesis. Science 275(5302): 964-967, 1997. (Pubitemid 27087709)
17. Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, Oz MC, Hicklin DJ, Witte L, Moore MA and Rafii S: VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 95(3): 952-958, 2000.
18. Chang YT, Chang MC, Wei SC, Tien YW, Hsu C, Liang PC, Tsao PN, Jan IS and Wong JM: Serum vascular endothelial growth factor/soluble vascular endothelial growth factor receptor 1 ratio is an independent prognostic marker in pancreatic cancer. Pancreas 37(2): 145-150, 2008.
19. Kalka C, Masuda H, Takahashi T, Gordon R, Tepper O, Gravereaux E, Pieczek A, Iwaguro H, Hayashi SI, Isner JM and Asahara T: Vascular endothelial growth factor(165) gene transfer augments circulating endothelial progenitor cells in human subjects. Circ Res 86(12): 1198-1202, 2000.
20. Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, DiPalma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, Vandendriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D and Persico MG: Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 7(5): 575-583, 2001.
21. Park JE, Chen HH, Winer J, Houck KA and Ferrara N: Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem 269(41): 25646-25654, 1994. (Pubitemid 24982909)