Porphyromonas gingivalis cell-induced hemagglutination and platelet aggregation

Periodontology 2000

Volumn 54, Issue 1, 2010, Pages 45-52

  Nakayama, Koji ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; ARGINGIPAIN, PORPHYROMONAS GINGIVALIS; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; HEMAGGLUTININ A, PORPHYROMONAS GINGIVALIS; LECTIN; LYS GINGIPAIN; LYS-GINGIPAIN;

ANIMAL; ARTICLE; CHRONIC PERIODONTITIS; HEMAGGLUTINATION; HUMAN; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; PORPHYROMONAS GINGIVALIS; PROTEIN BINDING; THROMBOCYTE AGGREGATION;

ADHESINS, BACTERIAL; ANIMALS; BACTERIAL PROTEINS; CHRONIC PERIODONTITIS; CYSTEINE ENDOPEPTIDASES; HEMAGGLUTINATION; HUMANS; LECTINS; PLATELET AGGREGATION; PORPHYROMONAS GINGIVALIS; PROTEIN BINDING;

EID: 77955757760     PISSN: 09066713     EISSN: 16000757     Source Type: Journal    
DOI: 10.1111/j.1600-0757.2010.00351.x     Document Type: Article

References (56)

1. Boyd J, McBride BC. Fractionation of hemagglutinating and bacterial binding adhesins of Bacteroides gingivalis. Infect Immun 1984, 45:403-409.
2. Byrne MF, Kerrigan SW, Corcoran PA, Atherton JC, Murray FE, Fitzgerald DJ, Cox DM. Helicobacter pylori binds von Willebrand factor and interacts with GPIb to induce platelet aggregation. Gastroenterology 2003, 124:1846-1854.
3. Chandad F, Mayrand D, Grenier D, Hinode D, Mouton C. Selection and phenotypic characterization of nonhemagglutinating mutants of Porphyromonas gingivalis. Infect Immun 1996, 64:952-958.
4. Chandad F, Mouton C. Antigenic, structural, and functional relationships between fimbriae and the hemagglutinating adhesin HA-Ag2 of Porphyromonas gingivalis. Infect Immun 1995, 63:4755-4763.
5. Chen YW, Iwai T, Umeda M, Nagasawa T, Huang Y, Takeuchi Y, Ishikawa I. Elevated IgG titers to periodontal pathogens related to Buerger disease. Int J Cardiol 2007, 122:79-81.
6. Curtis MA, Macey M, Slaney JM, Howells GL. Platelet activation by protease I of Porphyromonas gingivalis W83. FEMS Microbiol Lett 1993, 110:167-173.
7. Curtis MA, Kuramitsu HK, Lantz M, Nakayama K, Potempa J, Reynolds EC, Aduse-Opoku J. Molecular genetics and nomenclature of proteases of Porphyromonas gingivalis. J Periodontal Res 1999, 34:464-472.
8. DeCarlo AA, Nadkarni M, Paramaesvaran M, Yun PW, Collyer CA, Hunter N. Serum antibodies against the hemoglobin-binding domain (HA2) of Porphyromonas gingivalis. J Periodontal Res 2004, 39:228-235.
9. Deslauriers M, Mouton C. Epitope mapping of hemagglutinating adhesin HA-Ag2 of Bacteroides (Porphyromonas) gingivalis. Infect Immun 1992, 60:2791-2799.
10. Fitzgerald JR, Foster TJ, Cox D. The interaction of bacterial pathogens with platelets. Nat Rev Microbiol 2006, 4:445-457.
11. Frazer LT, O'Brien-Simpson NM, Slakeski N, Walsh KA, Veith PD, Chen CG, Barr IG, Reynolds EC. Vaccination with recombinant adhesins from the RgpA-Kgp proteinase-adhesin complex protects against Porphyromonas gingivalis infection. Vaccine 2006, 24:6542-6554.
12. Han N, Whitlock J, Progulske-Fox A. The hemagglutinin gene A (hagA) of Porphyromonas gingivalis 381 contains four large, contiguous, direct repeats. Infect Immun 1996, 64:4000-4007.
13. Hayashi H, Nagata A, Hinode D, Sato M, Nakamura R. Survey of a receptor protein in human erythrocytes for hemagglutinin of Porphyromonas gingivalis. Oral Microbiol Immunol 1992, 7:204-211.
14. Herzberg MC, MacFarlane GD, Liu P, Erickson PR. The platelet as an inflammatory cell in periodontal diseases: interaction with Porphyromonas gingivalis. Molecular Pathogenesis of Periodontal Disease 1994, 247-255. Genco RJ, Hamada S, Lehner T, McGhee JMergenhagen S. In, editors, Washington DC, ASM Press
15. Holt SC, Kesavalu L, Walker S, Ebersole JL. Virulence factors of Porphyromonas gingivalis. Periodontol 2000 1999, 20:168-238.
16. Hoover CI, Ng CY, Felton JR. Correlation of haemagglutination activity with trypsin-like protease activity of Porphyromonas gingivalis. Arch Oral Biol 1992, 37:515-520.
17. Inoshita E, Amano A, Hanioka T, Tamagawa H, Shizukuishi S, Tsunemitsu A. Isolation and some properties of exohemagglutinin from the culture medium of Bacteroides gingivalis 381. Infect Immun 1986, 52:421-427.
18. Iwai T, Inoue Y, Umeda M, Huang Y, Kurihara N, Koike M, Ishikawa I. Oral bacteria in the occluded arteries of patients with Buerger disease. J Vasc Surg 2005, 42:107-115.
19. Kaczmarek FS, Coykendall AL. Production of phenylacetic acid by strains of Bacteroides asaccharolyticus and Bacteroides gingivalis (sp. nov.). J Clin Microbiol 1980, 12:288-290.
20. Kadowaki T, Nakayama K, Okamoto K, Abe N, Baba A, Shi Y, Ratnayake DB, Yamamoto K. Porphyromonas gingivalis proteinases as virulence determinants in progression of periodontal diseases. J Biochem (Tokyo) 2000, 128:153-159.
21. Kadowaki T, Nakayama K, Yoshimura F, Okamoto K, Abe N, Yamamoto K. Arg-gingipain acts as a major processing enzyme for various cell surface proteins in Porphyromonas gingivalis. J Biol Chem 1998, 273:29072-29076.
22. Kelly CG, Booth V, Kendal H, Slaney JM, Curtis MA, Lehner TCG. The relationship between colonization and haemagglutination inhibiting and B cell epitopes of Porphyromonas gingivalis. Clin Exp Immunol 1997, 110:285-291.
23. Kerrigan SW, Douglas I, Wray A, Heath J, Byrne MF, Fitzgerald D, Cox DM. A role for glycoprotein Ib in Streptococcus sanguis-induced platelet aggregation. Blood 2002, 100:509-516.
24. Lamont RJ, Jenkinson HF. Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol Mol Biol Rev 1998, 62:1244-1263.
25. Lourbakos A, Yuan YP, Jenkins AL, Travis J, Andrade-Gordon P, Santulli R, Potempa J, Pike RN. Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity. Blood 2001, 97:3790-3797.
26. McQuibban GA, Gong JH, Tam EM, McCulloch CA, Clark-Lewis I, Overall CM. Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. Science 2000, 289:1202-1206.
27. Mouton C, Bouchard D, Deslauriers M, Lamonde L. Immunochemical identification and preliminary characterization of a nonfimbrial hemagglutinating adhesin of Bacteroides gingivalis. Infect Immun 1989, 57:566-573.
28. Mouton C, Chandad F. Hemagglutination and hemagglutinins. Biology of the Species Porphyromonas gingivalis 1993, 199-217. Shah HN, Mayrand DGenco RJ. In, editors, Boca Raton, FL, CRC Press
29. Mouton C, Ni Eidhin D, Deslauriers M, Lamy L. The hemagglutinating adhesion HA-Ag2 of Bacteroides gingivalis is distinct from fimbrilin. Oral Microbiol Immunol 1991, 6:6-11.
30. Naito M, Sakai E, Shi Y, Ideguchi H, Shoji M, Ohara N, Yamamoto K, Nakayama K. Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase. Mol Microbiol 2006, 59:152-167.
31. Nakayama K, Kadowaki T, Okamoto K, Yamamoto K. Construction and characterization of arginine-specific cysteine proteinase (Arg-gingipain)-deficient mutants of Porphyromonas gingivalis. Evidence for significant contribution of Arg-gingipain to virulence. J Biol Chem 1995, 270:23619-23626.
32. Nakayama K, Ratnayake DB, Tsukuba T, Kadowaki T, Yamamoto K, Fujimura S. Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalis. Mol Microbiol 1998, 27:51-61.
33. Nakayama K, Yoshimura F, Kadowaki T, Yamamoto K. Involvement of arginine-specific cysteine proteinase (Arg-gingipain) in fimbriation of Porphyromonas gingivalis. J Bacteriol 1996, 178:2818-2824.
34. Nguyen KA, DeCarlo AA, Paramaesvaran M, Collyer CA, Langley DB, Hunter N. Human responses to Porphyromonas gingivalis gingipain adhesin domains in subjects with chronic periodontitis. Infect Immun 2004, 72:1374-1382.
35. Nishikata M, Yoshimura F. Characterization of Porphyromonas (Bacteroides) gingivalis hemagglutinin as a protease. Biochem Biophys Res Commun 1991, 178:336-342.
36. Nishikata M, Yoshimura F, Nodasaka Y. Possibility of Bacteroides gingivalis hemagglutinin possessing protease activity revealed by inhibition studies. Microbiol Immunol 1989, 33:75-80.
37. Ogawa T, Hamada S. Hemagglutinating and chemotactic properties of synthetic peptide segments of fimbrial protein from Porphyromonas gingivalis. Infect Immun 1994, 62:3305-3310.
38. Okuda K, Ono M, Kato T. Neuraminidase-enhanced attachment of Bacteroides intermedius to human erythrocytes and buccal epithelial cells. Infect Immun 1989, 57:1635-1637.
39. Okuda K, Slots J, Genco RJ. Bacteroides gingivalis, Bacteroides asaccharolyticus, and Bacteroides melaninogenicus subspecies: cell surface morphology and adherence to erythrocytes and human buccal epithelia cells. Curr Microbiol 1981, 6:7-12.
40. Okuda K, Takazoe I. Haemagglutinating activity of Bacteroides melaninogenicus. Arch Oral Biol 1974, 19:415-416.
41. Pike R, McGraw W, Potempa J, Travis J. Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins. J Biol Chem 1994, 269:406-411.
42. Pike RN, Potempa J, McGraw W, Coetzer TH, Travis J. Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis. J Bacteriol 1996, 178:2876-2882.
43. Potempa J, Banbula A, Travis J. Role of bacterial proteinases in matrix destruction and modulation of host responses. Periodontol 2000 2000, 24:153-192.
44. Saglie FR, Marfany A, Camargo P. Intragingival occurrence of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis in active destructive periodontal lesions. J Periodontol 1988, 59:259-265.
45. Sato K, Naito M, Yukitake H, Hirakawa H, Shoji M, McBride MJ, Rhodes RG, Nakayama K. A protein secretion system linked to bacteroidete gliding motility and pathogenesis. Proc Natl Acad Sci USA 2010, 107:276-281.
46. Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K. Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an inter-domain regional peptide. J Bacteriol 2007, 189:3977-3986.
47. Shi Y, Kong W, Nakayama K. Human lactoferrin binds and removes the hemoglobin receptor protein of the periodontopathogen Porphyromonas gingivalis. J Biol Chem 2000, 275:30002-30008.
48. Shi Y, Ratnayake DB, Okamoto K, Abe N, Yamamoto K, Nakayama K. Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA, rgpB, kgp, and hagA. J Biol Chem 1999, 274:17955-17960.
49. Shibata Y, Hayakawa M, Takiguchi H, Shiroza T, Abiko Y. Determination and characterization of the hemagglutinin-associated short motifs found in Porphyromonas gingivalis multiple gene products. J Biol Chem 1999, 274:5012-5020.
50. Shoji M, Naito M, Yukitake H, Sato K, Sakai E, Ohara N, Nakayama K. The major structural components of two cell-surface filaments of Porphyromonas gingivalis are matured through lipoprotein precursors. Mol Microbiol 2004, 52:1513-1525.
51. Slots J, Gibbons RJ. Attachment of Bacteroides melaninogenicus subsp. asaccharolyticus to oral surfaces and its possible role in colonization of the mouth and of periodontal pockets. Infect Immun 1978, 19:254-264.
52. Sullam PM, Hyun WC, Szollosi J, Dong J, Foss WM, Lopez JA. Physical proximity and functional interplay of the glycoprotein Ib-IX-V complex and the Fc receptor FcγRIIA on the platelet plasma membrane. J Biol Chem 1998, 273:5331-5336.
53. Veith PD, Talbo GH, Slakeski N, Dashper SG, Moore C, Paolini RA, Reynolds EC. Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50. Biochem J 2002, 363:105-115.
54. Wu Y, Suzuki-Inoue K, Satoh K, Asazuma N, Yatomi Y, Berndt MC, Ozaki Y. Role of Fc receptor γ-chain in platelet glycoprotein Ib-mediated signaling. Blood 2001, 97:3836-3845.
55. Yoshimura F, Takahashi K, Nodasaka Y, Suzuki T. Purification and characterization of a novel type of fimbriae from the oral anaerobe Bacteroides gingivalis. J Bacteriol 1984, 160:949-957.
56. Zhang P, Lewis JP, Michalek SM, Katz J. Role of CD80 and CD86 in host immune responses to the recombinant hemagglutinin domain of Porphyromonas gingivalis gingipain and in the adjuvanticity of cholera toxin B and monophosphoryl lipid A. Vaccine 2007, 25:6201-6210.