Association study between antipsychotic-induced restless legs syndrome and polymorphisms of monoamine oxidase genes in schizophrenia

Human Psychopharmacology

Volumn 25, Issue 5, 2010, Pages 397-403

  Kang, Seung Gul ^a   Park, Young Min ^b   Choi, Jung Eun ^a   Lim, Se Won ^c   Lee, Heon Jeong ^a   Lee, Seung Hwan ^b   Kim, Yong Ku ^a   Kim, Seung Hyun ^a   Cho, Sung Nam ^d   Kim, Leen ^a  

^a Korea University College of Medicine   (South Korea)

^b Inje University College of Medicine   (South Korea)

^c Sungkyunkwan University School of Medicine   (South Korea)

^d Bugok National Hospital   (South Korea)

Author keywords

Antipsychotics; Gene gene interaction; Monoamine A and B genes; Polymorphism; Restless legs syndrome; Schizophrenia

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; NEUROLEPTIC AGENT; AMINE OXIDASE (FLAVIN CONTAINING);

ADULT; AGED; ARTICLE; DNA POLYMORPHISM; DRUG INDUCED DISEASE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESTLESS LEGS SYNDROME; SCHIZOPHRENIA; VARIABLE NUMBER OF TANDEM REPEAT; ALLELE; CHEMICALLY INDUCED; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; SEX DIFFERENCE; YOUNG ADULT;

ADULT; AGED; ALLELES; ANTIPSYCHOTIC AGENTS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; KOREA; MALE; MIDDLE AGED; MONOAMINE OXIDASE; POLYMORPHISM, GENETIC; RESTLESS LEGS SYNDROME; SCHIZOPHRENIA; SEX FACTORS; YOUNG ADULT;

EID: 77955751719     PISSN: 08856222     EISSN: 10991077     Source Type: Journal    
DOI: 10.1002/hup.1130     Document Type: Article

References (48)

1. Allen RP, Picchietti D, Hening WA, Trenkwalder C, Walters AS, Montplaisi J. 2003. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless leg syndrome diagnosis and epidemiology workshop at the National Institute of Health. Sleep Med 4: 101-119.
2. Balciuniene J, Emilsson L, Oreland L, Pettersson U, Jazin E. 2002. Investigation of the functional effect of monoamine oxidase polymorphisms in human brain. Hum Genet 110: 1-7. (Pubitemid 36067410)
3. Barnes TR. 1989. A rating scale for drug-induced akathisia. Br J Psychiatry 154: 672-676.
4. Bjorvatn B, Leissner L, Ulfberg J, et al. 2005. Prevalence, severity and risk factors of restless legs syndrome in the general adult population in two Scandinavian countries. Sleep Med 6: 307-312. (Pubitemid 40867820)
5. Castner SA, Xiao L, Becker JB. 1993. Sex differences in striatal dopamine: in vivo microdialysis and behavioral studies. Brain Res 610: 127-134. (Pubitemid 23144432)
6. Cavalli-Sforza LL, Menozzi P, Piazza A. 1994. The History and Geography of Human Genes. Princeton University Press: Princeton, NJ.
7. Chen S, Ondo WG, Rao S, Li L, Chen Q, Wang Q. 2004. Genomewide linkage scan identifies a novel susceptibility locus for RLS on chromosome 9p. Am J Hum Genet 74: 876-889.
8. Cho YW, Shin WC, Yun CH, et al. 2008. Epidemiology of restless legs syndrome in Korean adults. Sleep 31: 219-223. (Pubitemid 351536523)
9. Cho CH, Kang SG, Choi JE, Park YM, Lee HJ, Kim L. 2009. Association between antipsychotic-induced restless legs syndrome and tyrosine hydroxylase gene polymorphism. Psychiatry Invest 6: 130-136.
10. Coron B, Campion D, Thibaut F, et al. 1996. Association study between schizophrenia and monoamine oxidase A and B DNA polymorphisms. Psychiatry Res 62: 221-226. (Pubitemid 26189428)
11. Desautels A, Turecki G, Montplaisir J, et al. 2002. Evidence for a genetic association between monoamine oxidase A and restless legs syndrome. Neurology 59: 215-219. (Pubitemid 34779180)
12. Desautels A, Turecki G, Montplaisir J, et al. 2005. Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity. Arch Neurol 62: 591-596. (Pubitemid 40489891)
13. Garpenstrand H, Ekblom J, Forslund K, Rylander G, Oreland L. 2000. Platelet monoamine oxidase activity is related to MAOB intron 13 genotype. J Neural Transm 107: 523-530. (Pubitemid 30251736)
14. Gudelsky GA, Porter JC. 1981. Sex-related difference in the release of dopamine into hypophysial portal blood. Endocrinology 109: 1394-1398. (Pubitemid 12197421)
15. Han OS, Hong JP. 2000. Structured Clinical Interview for DSM-IV Axis I Disorder - Korean Version. Hana Medical Publishing: Seoul.
16. Horiguchi J, Yamashita H, Mizuno S, et al. 1999. Nocturnal eating/drinking syndrome and neuroleptic-induced restless syndrome. Int Clin Psychopharmacol 14: 33-36. (Pubitemid 29054591)
17. Hsu YP, Powell JF, Sims KB, Breakefield XO. 1989. Molecular genetics of the monoamine oxidases. J Neurochem 53: 12-18.
18. Kang SG, Lee HJ, Choi JE, et al. 2007a. Possible association between G-protein β3 subunit C825T polymorphism and antipsychotic-induced restless legs syndrome in schizophrenia. Acta Neuropsychiatr 19: 351-356.
19. Kang SG, Lee HJ, Jung SW, et al. 2007b. Characteristics and clinical correlates of restless legs syndrome in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 31: 1078-1083. (Pubitemid 46810100)
20. Kang SG, Lee HJ, Choi JE, et al. 2008. Association study between antipsychotics-induced restless legs syndrome and polymorphisms of dopamine D1, D2, D3, and D4 receptor genes in schizophrenia. Neuropsychobiology 57: 49-54.
21. Kemlink D, Plazzi G, Vetrugno R, et al. 2008. Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13. Neurogenetics 9: 75-82.
22. Kim JW. 2003. Association study and the population admixture. In Human Neurobehavioral Genetics in the 21st Century - Winter Workshop In: Korean Society of Biological Psychiatry. Korean Society of Biological Psychiatry: Seoul.
23. Kim JY, Choi C, Shin K, et al. 2005. Prevalence of restless legs syndrome and associated factors in the Korean adult population: the Korean Health and Genome Study. Psychiatry Clin Neurosci 59: 350-353. (Pubitemid 40897208)
24. Kritzer MF, Kohama SG. 1998. Ovarian hormones influence the morphology, distribution, and density of tyrosine hydroxylase immunoreactive axons in the dorsolateral prefrontal cortex of adult rhesus monkeys. J Comp Neurol 395: 1-17.
25. Levchenko A, Montplaisir JY, Dube MP, et al. 2004. The 14q restless legs syndrome locus in the French Canadian population. Ann Neurol 55: 887-891. (Pubitemid 38702587)
26. Levchenko A, Provost S, Montplaisir JY, et al. 2006. A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13. Neurology 67: 900-901. (Pubitemid 44394216)
27. Matsumoto C, Shinkai T, Hori H, Ohmori O, Nakamura J. 2004. Polymorphisms of dopamine degradation enzyme (COMT and MAO) genes and tardive dyskinesia in patients with schizophrenia. Psychiatry Res 127: 1-7. (Pubitemid 38916861)
28. McDermott JL, Liu B, Dluzen DE. 1994. Sex differences and effects of estrogen on dopamine and DOPAC release from the striatum of male and female CD-1 mice. Exp Neurol 125: 306-311. (Pubitemid 24076109)
29. Montplaisir J, Boucher S, Poirier G, Lavigne G, Lapierre O, Lesperance P. 1997. Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria. Mov Disord 12: 61-65. (Pubitemid 27032881)
30. Montplaisir J, Nicolas A, Denesle R, Gomez-Mancilla B. 1999. Restless legs syndrome improved by pramipexole: a double blind randomized trial. Neurology 52: 938-943. (Pubitemid 29161600)
31. Ondo W, Jankovic J. 1996. Restless legs syndrome: clinicoetiologic correlates. Neurology 47: 1435-1441. (Pubitemid 26422532)
32. Overall JE, Gorham DR. 1962. The Brief Psychiatric Rating Scale. Psychol Rep 10: 799-812.
33. Phillips B, Hening W, Britz P, Mannino D. 2006. Prevalence and correlates of restless legs syndrome: results from the 2005 National Sleep Foundation Poll. Chest 129: 76-80. (Pubitemid 43265245)
34. Pichler I, Marroni F, Volpato CB, et al. 2006. Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolate. Am J Hum Genet 79: 716-723. (Pubitemid 44452749)
35. Pinninti NR, Mago R, Townsend J, Doghramji K. 2005. Periodic restless legs syndrome associated with quetiapine use: a case report. J Clin Psychopharmacol 25: 617-618. (Pubitemid 41669066)
36. Pohjalainen T, Rinne JO, Nagren K, Syvalahti E, Hietala J. 1998. Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo. Am J Psychiatry 155: 768-773. (Pubitemid 28252655)
37. Richard BB. 2003. Sleep Medicine Pearls, 2nd edn. Mosby: Philadelphia.
38. Ruottinen HM, Partinen M, Hublin C, et al. 2000. An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. Neurology 54: 502-504. (Pubitemid 30078095)
39. Sabol SZ, Hu S, Hamer D. 1998. A functional polymorphism in the monoamine oxidase A gene promoter. Hum Genet 103: 273-279. (Pubitemid 28470076)
40. Soldatos CR, Dikeos DG, Paparrigopoulos TJ. 2003. The diagnostic validity of the Athens Insomnia Scale. J Psychosom Res 55: 263-267.
41. Turjanski N, Lees AJ, Brooks DJ. 1999. Striatal dopaminergic receptor dysfunction in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies. Neurology 52: 932-937. (Pubitemid 29161599)
42. Walters AS, Hickey K, Maltzman J, et al. 1996. A questionnaire study of 138 patients with restless legs syndrome: the 'Night-Walkers' survey. Neurology 46: 92-95.
43. Walters AS, LeBrocq C, Dhar A, et al. 2003. Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome. Sleep Med 4: 121-132. (Pubitemid 36527232)
44. Wei J, Hemmings GP. 2000. Searching for a locus for schizophrenia within chromosome Xp11. Am J Med Genet 96: 4-7. (Pubitemid 30077641)
45. Wetter TC, Stiasny K, Winkelmann J, et al. 1999. A randomized, controlled study of pergolide in patients with restless legs syndrome. Neurology 52: 944-950. (Pubitemid 29161601)
46. Wetter TC, Brunner J, Bronisch T. 2002. Restless legs syndrome probably induced by risperidone treatment. Pharmacopsychiatry 35: 109-111. (Pubitemid 34651917)
47. Winkelmann J, Schormair B, Lichtner P, et al. 2007. Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat Genet 39: 1000-1006. (Pubitemid 47185185)
48. Zhao JH. 2004. 2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis. Bioinformatics 20: 1325-1326.