Down-regulation of IL-6, IL-8, TNF-α and IL-1β by glucosamine in HaCaT cells, but not in the presence of TNF-α

Oncology Letters

Volumn 1, Issue 2, 2010, Pages 289-292

  Park, Kun ^a   Lee, Ji Hye ^a   Cho, Ho Chan ^b   Cho, Sun Young ^c   Cho, Jae We ^c  

^a Eulji University   (South Korea)

^b Daegu Bio Industry Center   (South Korea)

^c Keimyung University School of Medicine   (South Korea)

Author keywords

Glucosamine; HaCaT cells; Interleukin; Tumor necrosis factor

Indexed keywords

CURCUMIN; GLUCOSAMINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; HUMAN; HUMAN CELL; KERATINOCYTE; PROTEIN EXPRESSION;

EID: 77955737885     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol_00000051     Document Type: Article

References (24)

1. Damjanov N and Vojinovic J: Biologic therapy of rheumatoid arthritis. Srp Arh Celok Lek 137: 205-210, 2009.
2. Ding C, Cicuttini F, Li J and Jones G: Targeting IL-6 in the treatment of inflammatory and autoimmune diseases. Expert Opin Investig Drugs 18: 1457-1466, 2009.
3. Kovarikova M, Hofmanova J, Soucek K and Kozubik A: The effects of TNF-alpha and inhibitors of arachidonic acid metabolism on human colon HT-29 cells depend on differentiation status. Differentiation 72: 23-31, 2004.
4. Carlsen H, Alexander G, Austenaa LM, Ebihara K and Blomhoff R: Molecular imaging of the transcription factor NF-kappaB, a primary regulator of stress response. Mutat Res 551: 199-211, 2004.
5. Muthusamy V and Piva T J: The UV response of the skin: a review of the MAPK, NF kappa B and TNFalpha signal transduction pathways. Arch Dermatol Res: Sep. 16, 2009 (Epub ahead of print).
6. Leng H, Luo X, Ma L, Kang K and Zheng Z: Reversal of ultraviolet B-induced immunosuppression by inhibition of the extracellular signal-regulated mitogen-activated protein kinase. Photodermatol Photoimmunol Photomed 25: 264-269, 2009.
7. Neves BM, Cruz MT, Francisco V, Garcia-Rodriguez C, Silvestre R, Cordeiro-da-Silva A, Dinis AM, Batista MT, Duarte CB and Lopes MC: Differential roles of PI3-kinase, MAPKs and NF-kappaB on the manipulation of dendritic cell T(h)1/T(h)2 cytokine/chemokine polarizing profile. Mol Immunol 46: 2481-2492, 2009.
8. Ivanova IA, Nakrieko KA and Dagnino L: Phosphorylation by p38 MAP kinase is required for E2F1 degradation and keratinocyte differentiation. Oncogene 28: 52-62, 2009.
9. Hong H, Park YK, Choi MS, Ryu NH, Song DK, Suh SI, Nam KY, Park GY and Jang BC: Differential down-regulation of COX-2 and MMP-13 in human skin fibroblasts by glucosamine-hydrochloride. J Dermatol Sci 56: 43-50, 2009.
10. Hwang SM, Chen CY, Chen SS and Chen JC: Chitinous materials inhibit nitric oxide production by activated RAW 264.7 macrophages. Biochem Biophys Res Commun 271: 229-233, 2000.
11. Xing D, Feng W, Not LG, Miller AP, Zhang Y, Chen YF, Majid-Hassan E, Chatham JC and Oparil S: Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury. Am J Physiol Heart Circ Physiol 295: 335-342, 2008.
12. Kneass ZT and Marchase RB: Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils. J Biol Chem 280: 14579-14585, 2005.
13. Sinha R, Anderson DE, McDonald SS and Greenwald P: Cancer risk and diet in India. J Postgrad Med 49: 222-228, 2003.
14. Pari L, Tewas D and Eckel J: Role of curcumin in health and disease. Arch Physiol Biochem 114: 127-149, 2008.
15. Jiang ZY, Zou L, Shi SS, Lu YR, Dong J, Yang CH, Lu YC and Dai GK: Effects of curcumin on TNF-alpha and TGF-beta1 in serum and lung tissue of SiO(2)-induced fibrosis in mice. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25: 399-401, 2009.
16. Reuter S, Charlet J, Juncker T, Teiten MH, Dicato M and Diederich M: Effect of curcumin on nuclear factor kappaB signaling pathways in human chronic myelogenous K562 leukemia cells. Ann NY Acad Sci 1171: 436-447, 2009.
17. Wang SL, Li Y, Wen Y, Chen YF, Na LX, Li ST and Sun CH: Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway. Biomed Environ Sci 22: 32-39, 2009.
18. Rafi MM, Yadav PN and Rossi AO: Glucosamine inhibits LPS-induced COX-2 and iNOS expression in mouse macrophage cells (RAW 264.7) by inhibition of p38-MAP kinase and transcription factor NF-kappaB. Mol Nutr Food Res 51: 587-593, 2007.
19. Chesnokov V, Sun C and Itakura K: Glucosamine suppresses proliferation of human prostate carcinoma DU145 cells through inhibition of STAT3 signaling. Cancer Cell Int 9: 25-28, 2009.
20. Fox BA and Stephens MM: Glucosamine/chondroitin/primorine combination therapy for osteoarthritis. Drugs Today 45: 21-31, 2009.
21. Bonness S and Bieber T: Molecular basis of atopic dermatitis. Curr Opin Allergy Clin Immunol 7: 382-386, 2007.
22. Capon F, Trembath RC and Barker JN: An update on the genetics of psoriasis. Dermatol Clin 22: 339-347, 2004.
23. Deane JA and Hickey MJ: Molecular mechanisms of leukocyte trafficking in T-cell-mediated skin inflammation: insights from intravital imaging. Expert Rev Mol Med 11: e25, 2009.
24. Escobar J, Pereda J, Arduini A, Sandoval J, Sabater L, Aparisi L, Lopez-Rodas G and Sastre J: Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases. Curr Pharm Des 15: 3027-3042, 2009.