Influence of methotrexate exposure on outcome in patients treated with MBVP chemotherapy for primary central nervous system lymphoma

British Journal of Clinical Pharmacology

Volumn 70, Issue 3, 2010, Pages 367-375

  Blasco, Hélène ^a   Senecal, Delphine ^b   Le Gouge, Amélie ^a   Pinard, Emmanuelle ^b   Benz De Bretagne, Isabelle ^b   Colombat, Philippe ^a,b   Hulot, Jean Sébastien ^c   Chatelut, Etienne ^d   Le Guellec, Chantal ^a,b  

^a UNIVERSITÉ DE TOURS   (France)

^b UNIVERSITY HOSPITAL OF TOURS   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

Dose response relationship; Methotrexate; Pharmacokinetics; Primary central nervous system lymphoma

Indexed keywords

CARMUSTINE; CYTARABINE; ETOPOSIDE; FOLINIC ACID; METHOTREXATE; METHYLPREDNISOLONE;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD TOXICITY; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; DISEASE FREE SURVIVAL; DRUG DOSE REDUCTION; DRUG EXPOSURE; DRUG MEGADOSE; FEMALE; HUMAN; MALE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NEPHROTOXICITY; OVERALL SURVIVAL; PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA; PRIMARY TUMOR; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TREATMENT FAILURE; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CENTRAL NERVOUS SYSTEM NEOPLASMS; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LYMPHOMA; MALE; METHOTREXATE; MIDDLE AGED; RETROSPECTIVE STUDIES; STATISTICS AS TOPIC; TIME FACTORS; TREATMENT OUTCOME;

EID: 77955734236     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2010.03712.x     Document Type: Article

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