Comparison of efficacy and toxicity of short-course carbon ion radiotherapy for hepatocellular carcinoma depending on their proximity to the porta hepatis

Radiotherapy and Oncology

Volumn 96, Issue 2, 2010, Pages 231-235

  Imada, Hiroshi ^a,b   Kato, Hirotoshi ^a   Yasuda, Shigeo ^a   Yamada, Shigeru ^a   Yanagi, Takeshi ^a   Kishimoto, Riwa ^a   Kandatsu, Susumu ^a   Mizoe, Jun Etsu ^a   Kamada, Tadashi ^a   Yokosuka, Osamu ^b   Tsujii, Hirohiko ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

Carbon ion; Hepatocellular carcinoma; Porta hepatis; Radiotherapy

Indexed keywords

ADULT; AGED; ARTICLE; BILE DUCT OBSTRUCTION; BLOOD TOXICITY; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; ION THERAPY; LIVER CELL CARCINOMA; LIVER HILUS; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PATIENT SAFETY; PORTAL VEIN; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RADIATION FIELD; RADIATION INJURY; THERAPY EFFECT; TREATMENT DURATION; TREATMENT PLANNING; TUMOR LOCALIZATION;

ADULT; AGED; AGED, 80 AND OVER; CARBON RADIOISOTOPES; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; IONS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PORTAL VEIN; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 77955715338     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2010.05.019     Document Type: Article

References (40)

1. F.X. Bosch, J. Ribes, and J. Borras Epidemiology of primary liver cancer Semin Liver Dis 19 1999 271 285
2. R. Phillips, and K. Murakami Preliminary neoplasms of the liver. Results of radiation therapy Cancer 13 1960 714 720
3. G.B. Stillwagon, S.E. Order, and C. Guse 194 Hepatocellular cancers treated by radiation and chemotherapy combinations: Toxicity and response: a Radiation Therapy Oncology Group study Int J Radiat Oncol Biol Phys 17 1989 1223 1229
4. J.M. Robertson, T.S. Lawrence, and L.M. Dworzanin Treatment of primary hepatobiliary cancers with conformal radiation therapy and regional chemotherapy J Clin Oncol 11 1993 1286 1293
5. R. Toya, R. Murakami, and Y. Baba Conformal radiation therapy for portal vein tumor thrombosis of hepatocellular carcinoma Radiother Oncol 84 2007 266 271
6. M. Xi, M.Z. Liu, and X.W. Deng Defining internal target volume (ITV) for hepatocellular carcinoma using four-dimensional CT Radiother Oncol 84 2007 272 278
7. J.D. Zhao, Z.Y. Xu, and J. Zhu Application of active breathing control in 3-dimensional conformal radiation therapy for hepatocellular carcinoma: the feasibility and benefit Radiother Oncol 87 2008 439 444
8. H.D. Suit, M. Goitein, and J. Munzenrider Increased efficacy of radiation therapy by use of proton beam Strahlenther Onkol 166 1990 40 44
9. Y. Matsuzaki, T. Osuga, and Y. Saito A new, effective, and safe therapeutic option using proton irradiation for hepatocellular carcinoma Gastroenterology 106 1994 1032 1041
10. Y. Matsuzaki The efficacy of powerful proton radiotherapy for hepatocellular carcinoma-long term effects and QOL Ann Cancer Res Ther 7 1998 9 17
11. E.A. Blakely, F.Q.H. Ngo, and S.B. Curtis Heavy ion radiobiology: cellular studies Adv Radiat Biol 11 1984 295 378
12. J.R. Castro Future research strategy for heavy ion radiotherapy H.D. Kogelnih, Progress in radio-oncology 1995 Monduzzi Editore Bologna 643 648
13. K. Sato, H. Yamada, and K. Ogawa Performance of HIMAC Nucl Phys A588 1995 229 234
14. T. Kanai, Y. Furusawa, K. Fukutsu, H. Itsukaichi, K. Eguchi-Kasai, and H. Ohara Irradiation of mixed beam and design of spread-out Bragg peak for heavy-ion radiotherapy Radiat Res 147 1997 78 85
15. T. Kanai, M. Endo, and S. Minohara Biophysical characteristics of HIMAC clinical irradiation system for heavy-ion radiation therapy Int J Radiat Oncol Biol Phys 44 1999 201 210
16. H. Tsujii, S. Morita, and T. Miyamoto Preliminary results of phase I/II carbon ion therapy J Brachyther Int 13 1997 1 8
17. H. Kato, H. Tsujii, and T. Miyamoto Results of the first prospective study of carbon ion radiotherapy for hepatocellular carcinoma with liver cirrhosis Int J Radiat Oncol Biol Phys 59 2004 1468 1476
18. H. Tsujii, J.E. Mizoe, and T. Kamada Overview of clinical experiences on carbon ion radiotherapy at NIRS Radiother Oncol 73 2004 S41 49
19. H. Kato, S. Yamada, and S. Yasuda Phase II study of short-course carbon ion radiotherapy (52.8 GyE/4-fraction/1-week) for hepatocellular carcinoma Hepatology 42 2005 381A
20. I. Ikai, S. Arii, and M. Okazaki Report of the 17th nationwide follow-up survey of primary liver cancer in Japan Hepatol Res 37 2007 676 691
21. M.F. Mulcahy Management of hepatocellular cancer Curr Treat Options Oncol 6 2005 423 435
22. V. Mazzaferro, E. Regalia, and R. Doci Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis N Engl J Med 334 1996 693 699
23. J.M. Llovet, J. Fuster, and J. Bruix Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation Hepatology 30 1999 1434 1440
24. H.Y. Yoo, C.H. Patt, and J.F. Geschwind The outcome of liver transplantation in patients with hepatocellular carcinoma in the United States between 1988 and 2001: 5-year survival has improved significantly with time J Clin Oncol 21 2003 4329 4335
25. B.W. Kuvshinoff, and D.M. Ota Radiofrequency ablation of liver tumors: influence of technique and tumor size Surgery 132 2002 605 611
26. S. Shiina, T. Teratani, and S. Obi A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma Gastroenterology 129 2005 122 130
27. M. Sato, Y. Watanabe, and S. Ueda Microwave coagulation therapy for hepatocellular carcinoma Gastroenterology 110 1996 1507 1514
28. E.J. Patterson, C.H. Scudamore, and D.A. Owen Radiofrequency ablation of porcine liver in vivo: effects of blood flow and treatment time on lesion size Ann Surg 227 1998 559 565
29. T. Livraghi, L. Solbiati, and M.F. Meloni Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study Radiology 226 2003 441 451
30. T. Nakazawa, S. Kokubu, and A. Shibuya Radiofrequency ablation of hepatocellular carcinoma: correlation between local tumor progression after ablation and ablative margin AJR Am J Roentgenol 188 2007 480 488
31. T. Ohnishi, I. Yasuda, and Y. Nishigaki Intraductal chilled saline perfusion to prevent bile duct injury during percutaneous radiofrequency ablation for hepatocellular carcinoma J Gastroenterol Hepatol 23 2008 e410 415
32. J.M. Llovet, C. Bru, and J. Bruix Prognosis of hepatocellular carcinoma: the BCLC staging classification Semin liver Dis 19 1999 329 338
33. J.M. Llovet, A. Burroughs, and J. Bruix Hepatocellular carcinoma Lancet 362 2003 1907 1917
34. S. Minohara, T. Kanai, M. Endo, K. Noda, and M. Kanazawa Respiratory gated irradiation system for heavy-ion radiotherapy Int J Radiat Oncol Biol Phys 47 2000 1097 1103
35. M. Suzuki, Y. Kase, H. Yamaguchi, T. Kanai, and K. Ando Relative biological effectiveness for cell-killing effect on various human cell lines irradiated with heavy-ion medical accelerator in Chiba (HIMAC) carbon-ion beams Int J Radiat Oncol Biol Phys 48 2000 241 250
36. K. Hasegawa, N. Kokudo, and H. Imamura Prognostic impact of anatomic resection for hepatocellular carcinoma Ann Surg 242 2005 252 259
37. S. Rossi, F. Garbagnati, and R. Lencioni Percutaneous radio-frequency thermal ablation of nonresectable hepatocellular carcinoma after occlusion of tumor blood supply Radiology 217 2000 119 126
38. J.P. McGhana, and G.D. Dodd 3rd Radiofrequency ablation of the liver: current status AJR Am J Roentgenol 176 2001 3 16
39. T. de Baere, A. Denys, and B.J. Wood Radiofrequency liver ablation: experimental comparative study of water-cooled versus expandable systems AJR Am J Roentgenol 176 2001 187 192
40. M. Mizumoto, K. Tokuuye, and S. Sugahara Proton beam therapy for hepatocellular carcinoma adjacent to the prota hepatis Int J Radiat Oncol Biol Phys 71 2008 462 467