-
1
-
-
53249123632
-
-
4th edn. IARC Press: Lyon
-
Swerdlow SH, Campo E, Harris NL, Pileri SA, Stein H, Thiele J et al. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th edn. IARC Press: Lyon, 2008.
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
-
-
Swerdlow, S.H.1
Campo, E.2
Harris, N.L.3
Pileri, S.A.4
Stein, H.5
Thiele, J.6
-
2
-
-
19944427559
-
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
-
Stone RM, DeAngelo DJ, Klimek V, Galinsky I, Estey E, Nimer SD et al. Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412. Blood 2005; 105: 54-60.
-
(2005)
Blood
, vol.105
, pp. 54-60
-
-
Stone, R.M.1
Deangelo, D.J.2
Klimek, V.3
Galinsky, I.4
Estey, E.5
Nimer, S.D.6
-
3
-
-
33751173636
-
A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy
-
Knapper S, Burnett AK, Littlewood T, Kell WJ, Agrawal S, Chopra R et al. A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy. Blood 2006; 108: 3262-3270.
-
(2006)
Blood
, vol.108
, pp. 3262-3270
-
-
Knapper, S.1
Burnett, A.K.2
Littlewood, T.3
Kell, W.J.4
Agrawal, S.5
Chopra, R.6
-
4
-
-
19944431093
-
A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML)or not amenable to conventional therapy for the disease
-
Fiedler W, Serve H, Dohner H, Schwittay M, Ottmann OG, O0Farrell AM et al. A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML)or not amenable to conventional therapy for the disease. Blood 2005; 105: 986-993.
-
(2005)
Blood
, vol.105
, pp. 986-993
-
-
Fiedler, W.1
Serve, H.2
Dohner, H.3
Schwittay, M.4
Ottmann, O.G.5
O'Farrell, A.M.6
-
5
-
-
39149129114
-
Mutant FLT3: A direct target of sorafenib in acute myelogenous leukemia
-
Zhang W, Konopleva M, Shi YX, McQueen T, Harris D, Ling X et al. Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia. J Natl Cancer Inst 2008; 100: 184-198.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 184-198
-
-
Zhang, W.1
Konopleva, M.2
Shi, Y.X.3
McQueen, T.4
Harris, D.5
Ling, X.6
-
6
-
-
69249221392
-
Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: Sustained regression before and after allogeneic stem cell transplantation
-
Metzelder S, Wang Y, Wollmer E, Wanzel M, Teichler S, Chaturvedi A et al. Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation. Blood 2009; 113: 6567-6571.
-
(2009)
Blood
, vol.113
, pp. 6567-6571
-
-
Metzelder, S.1
Wang, Y.2
Wollmer, E.3
Wanzel, M.4
Teichler, S.5
Chaturvedi, A.6
-
7
-
-
30144432781
-
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain
-
Heidel F, Solem FK, Breitenbuecher F, Lipka DB, Kasper S, Thiede MH et al. Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain. Blood 2006; 107: 293-300.
-
(2006)
Blood
, vol.107
, pp. 293-300
-
-
Heidel, F.1
Solem, F.K.2
Breitenbuecher, F.3
Lipka, D.B.4
Kasper, S.5
Thiede, M.H.6
-
8
-
-
66149152278
-
FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro
-
von Bubnoff N, Engh RA, Aberg E, Sanger J, Peschel C, Duyster J. FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro. Cancer Res 2009; 69: 3032-3041.
-
(2009)
Cancer Res
, vol.69
, pp. 3032-3041
-
-
Von Bubnoff, N.1
Engh, R.A.2
Aberg, E.3
Sanger, J.4
Peschel, C.5
Duyster, J.6
-
9
-
-
4644240387
-
Prediction of resistance to small molecule FLT3 inhibitors: Implications for molecularly targeted therapy of acute leukemia
-
Cools J, Mentens N, Furet P, Fabbro D, Clark JJ, Griffin JD et al. Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia. Cancer Res 2004; 64: 6385-6389.
-
(2004)
Cancer Res
, vol.64
, pp. 6385-6389
-
-
Cools, J.1
Mentens, N.2
Furet, P.3
Fabbro, D.4
Clark, J.J.5
Griffin, J.D.6
-
10
-
-
35048848955
-
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia
-
Lee BH, Tothova Z, Levine RL, Anderson K, Buza-Vidas N, Cullen DE et al. FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia. Cancer Cell 2007; 12: 367-380.
-
(2007)
Cancer Cell
, vol.12
, pp. 367-380
-
-
Lee, B.H.1
Tothova, Z.2
Levine, R.L.3
Anderson, K.4
Buza-Vidas, N.5
Cullen, D.E.6
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