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Volumn 48, Issue 8, 2010, Pages 497-503

Non-concurrent dosing attenuates the pharmacokinetic interaction between amlodipine and simvastatin

Author keywords

Amlodipine; Cytochrome P 450; Drug interaction; Non concurrent dosing; Simvastatin

Indexed keywords

AMLODIPINE; AMLODIPINE BESYLATE; SIMVASTATIN;

EID: 77955703973     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CPP48497     Document Type: Article
Times cited : (22)

References (25)
  • 3
    • 0015780788 scopus 로고
    • Dose-dependent drug metabolism during the absorptive phase
    • Barr WH, Aceto T, Jr, Chung M, Shukur M. Dose-dependent drug metabolism during the absorptive phase. Rev Can Biol. 1973; 32 (Suppl): 42.
    • (1973) Rev Can Biol , vol.32 , Issue.SUPPL. , pp. 42
    • Barr, W.H.1    Aceto Jr., T.2    Chung, M.3    Shukur, M.4
  • 4
    • 0035722796 scopus 로고    scopus 로고
    • Amlodipine bioequivalence study: Quantification by liquid chromatography coupled to tandem mass spectrometry
    • Carvalho M, Oliveira CH, Mendes GD, Sucupira M, Moraes ME, De Nucci G. Amlodipine bioequivalence study: quantification by liquid chromatography coupled to tandem mass spectrometry. Biopharm Drug Dispos. 2001; 22: 383-390.
    • (2001) Biopharm Drug Dispos , vol.22 , pp. 383-390
    • Carvalho, M.1    Oliveira, C.H.2    Mendes, G.D.3    Sucupira, M.4    Moraes, M.E.5    De Nucci, G.6
  • 5
    • 0033741360 scopus 로고    scopus 로고
    • Does differing metabolism by cytochrome P450 have clinical importance?
    • Davidson MH. Does differing metabolism by cytochrome P450 have clinical importance? Curr Atheroscler Rep. 2000; 2: 14-19.
    • (2000) Curr Atheroscler Rep , vol.2 , pp. 14-19
    • Davidson, M.H.1
  • 6
    • 11244283910 scopus 로고    scopus 로고
    • Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors
    • Fujino H, Saito T, Tsunenari Y, Kojima J, Sakaeda T. Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors. Xenobiotica. 2004; 34: 961-971.
    • (2004) Xenobiotica , vol.34 , pp. 961-971
    • Fujino, H.1    Saito, T.2    Tsunenari, Y.3    Kojima, J.4    Sakaeda, T.5
  • 7
    • 0028234586 scopus 로고
    • Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily
    • Gorski JC, Hall SD, Jones DR, VandenBranden M, Wrighton SA. Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily. Biochem Pharmacol. 1994; 47: 1643-1653.
    • (1994) Biochem Pharmacol , vol.47 , pp. 1643-1653
    • Gorski, J.C.1    Hall, S.D.2    Jones, D.R.3    VandenBranden, M.4    Wrighton, S.A.5
  • 9
    • 0025860978 scopus 로고
    • Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4
    • Guengerich FP, Brian WR, Iwasaki M, Sari MA, Baarnhielm C, Berntsson P. Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4. J Med Chem. 1991; 34: 1838-1844.
    • (1991) J Med Chem , vol.34 , pp. 1838-1844
    • Guengerich, F.P.1    Brian, W.R.2    Iwasaki, M.3    Sari, M.A.4    Baarnhielm, C.5    Berntsson, P.6
  • 10
    • 0033576261 scopus 로고    scopus 로고
    • Drug interactions and the statins
    • Herman RJ. Drug interactions and the statins. CMAJ. 1999; 161: 1281-1286.
    • (1999) CMAJ , vol.161 , pp. 1281-1286
    • Herman, R.J.1
  • 11
    • 0032773854 scopus 로고    scopus 로고
    • Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation
    • Jones DR, Gorski JC, Hamman MA, Mayhew BS, Rider S, Hall SD. Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation. J Pharmacol Exp Ther. 1999; 290: 1116-1125.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 1116-1125
    • Jones, D.R.1    Gorski, J.C.2    Hamman, M.A.3    Mayhew, B.S.4    Rider, S.5    Hall, S.D.6
  • 12
    • 0033977858 scopus 로고    scopus 로고
    • The effect of staggered dosing of sucralfate on oral bioavailability of sparfloxacin
    • Kamberi M, Nakashima H, Ogawa K, Oda N, Nakano S. The effect of staggered dosing of sucralfate on oral bioavailability of sparfloxacin. Br J Clin Pharmacol. 2000; 49: 98-103.
    • (2000) Br J Clin Pharmacol , vol.49 , pp. 98-103
    • Kamberi, M.1    Nakashima, H.2    Ogawa, K.3    Oda, N.4    Nakano, S.5
  • 13
    • 0031670167 scopus 로고    scopus 로고
    • Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations
    • Kantola T, Kivisto KT, Neuvonen PJ. Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther. 1998; 64: 177-182.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 177-182
    • Kantola, T.1    Kivisto, K.T.2    Neuvonen, P.J.3
  • 14
    • 0034033399 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: Prediction of in vivo drug-drug interactions
    • Katoh M, Nakajima M, Shimada N, Yamazaki H, Yokoi T. Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions. Eur J Clin Pharmacol. 2000; 55: 843-852.
    • (2000) Eur J Clin Pharmacol , vol.55 , pp. 843-852
    • Katoh, M.1    Nakajima, M.2    Shimada, N.3    Yamazaki, H.4    Yokoi, T.5
  • 15
    • 0028139996 scopus 로고
    • Effect of sucralfate on absorption of norfloxacin and ofloxacin
    • Lehto P, Kivisto KT. Effect of sucralfate on absorption of norfloxacin and ofloxacin. Antimicrob Agents Chemother. 1994; 38: 248-251.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 248-251
    • Lehto, P.1    Kivisto, K.T.2
  • 18
    • 45549091043 scopus 로고    scopus 로고
    • Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin
    • Neuvonen PJ, Backman JT, Niemi M. Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin. Clin Pharmacokinet. 2008; 47: 463-474.
    • (2008) Clin Pharmacokinet , vol.47 , pp. 463-474
    • Neuvonen, P.J.1    Backman, J.T.2    Niemi, M.3
  • 19
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT. Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. Clin Pharmacol Ther. 2006; 80: 565-581.
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 20
    • 20444503924 scopus 로고    scopus 로고
    • Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension
    • Nishio S, Watanabe H, Kosuge K, Uchida S, Hayashi H, Ohashi K. Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension. Hypertens Res. 2005; 28: 223-227.
    • (2005) Hypertens Res , vol.28 , pp. 223-227
    • Nishio, S.1    Watanabe, H.2    Kosuge, K.3    Uchida, S.4    Hayashi, H.5    Ohashi, K.6
  • 21
    • 0038336614 scopus 로고    scopus 로고
    • The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6
    • Prueksaritanont T, Ma B, Yu N. The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6. Br J Clin Pharmacol. 2003; 56: 120-124.
    • (2003) Br J Clin Pharmacol , vol.56 , pp. 120-124
    • Prueksaritanont, T.1    Ma, B.2    Yu, N.3
  • 22
    • 0037380313 scopus 로고    scopus 로고
    • Timed-release formulation to avoid drug-drug interaction between diltiazem and midazolam
    • Sawada T, Sako K, Yoshihara K, Nakamura K, Yokohama S, Hayashi M. Timed-release formulation to avoid drug-drug interaction between diltiazem and midazolam. J Pharm Sci. 2003; 92: 790-797.
    • (2003) J Pharm Sci , vol.92 , pp. 790-797
    • Sawada, T.1    Sako, K.2    Yoshihara, K.3    Nakamura, K.4    Yokohama, S.5    Hayashi, M.6
  • 23
    • 4644301418 scopus 로고    scopus 로고
    • Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP-1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: Analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil
    • Shitara Y, Hirano M, Sato H, Sugiyama Y. Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP-1B1:SLC21A6)- mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil. J Pharmacol Exp Ther. 2004; 311: 228-236.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 228-236
    • Shitara, Y.1    Hirano, M.2    Sato, H.3    Sugiyama, Y.4
  • 24
  • 25
    • 0024263032 scopus 로고
    • Amlodipine pharmacokinetics in healthy volunteers
    • Williams DM, Cubeddu LX. Amlodipine pharmacokinetics in healthy volunteers. J Clin Pharmacol. 1988; 28: 990-994.
    • (1988) J Clin Pharmacol , vol.28 , pp. 990-994
    • Williams, D.M.1    Cubeddu, L.X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.