Construction of a novel cationic polymeric liposomes formed from PEgylated octadecyl-quaternized lysine modified chitosan/cholesterol for enhancing storage stability and cellular uptake efficiency

Biotechnology and Bioengineering

Volumn 106, Issue 6, 2010, Pages 952-962

  Wang, Hanjie ^a   Zhao, Peiqi ^b   Liang, Xiaofei ^a   Song, Tao ^a   Gong, Xiaoqun ^a   Niu, Ruifang ^b   Chang, Jin ^a  

^a TIANJIN UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Chitosan; Nanoparticles; PEGylated octadecyl quaternized lysine modified chitosan (PEG OQLCS); Polymeric liposome

Indexed keywords

CALCEIN; CELLULAR UPTAKE EFFICIENCY; DELIVERY VECTOR; DESIGN AND CONSTRUCTION; ENCAPSULATION EFFICIENCY; FLOW CYTOMETRY ANALYSIS; HIGH STABILITY; HUMAN PLASMAS; MODIFIED CHITOSAN; OCTADECYL; PHOSPHATE-BUFFERED SALINES; POLYMERIC LIPOSOMES; STORAGE STABILITY; TUMOR CELLS;

AMINO ACIDS; CHITIN; CHITOSAN; DEIONIZED WATER; ENCAPSULATION; FLOW CYTOMETRY; LIPOSOMES; NANOPARTICLES; PHOSPHOLIPIDS; SALINE WATER; STABILITY; ZETA POTENTIAL;

POLYMERS;

CALCEIN; CHITOSAN DERIVATIVE; CHOLESTEROL; LIPOSOME; NANOPARTICLE; PEGYLATED OCTADECYL QUATERNIZED LYSINE MODIFIED CHITOSAN; PHOSPHATE BUFFERED SALINE; POLYMER; POLYMERIC LIPOSOME; UNCLASSIFIED DRUG; WATER; CHITOSAN; DRUG CARRIER; FLUORESCEIN DERIVATIVE; LYSINE;

ARTICLE; CELL TRANSPORT; COMPARATIVE STUDY; DERIVATIZATION; DRUG DELIVERY SYSTEM; ENCAPSULATION; FLOW CYTOMETRY; FLUOROMETRY; MOLECULAR STABILITY; PHARMACEUTICAL ENGINEERING; PLASMA; POLYMERIZATION; SPECTROPHOTOMETER; STORAGE TEMPERATURE; TUMOR CELL; ANALOGS AND DERIVATIVES; DRUG STABILITY; HUMAN; SYNTHESIS; TUMOR CELL LINE;

CELL LINE, TUMOR; CHITOSAN; CHOLESTEROL; DRUG CARRIERS; DRUG STABILITY; FLUORESCEINS; HUMANS; LIPOSOMES; LYSINE;

EID: 77955700855     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22773     Document Type: Article

References (20)

1. Bangham AD, Standish MM, Watkins JC. 1965. Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 13(1):238.
2. Chan P, Kurisawa M, Chung JE, Yang YY. 2007. Synthesis and characterization of chitosan-g-poly(ethylene glycol)-folate as a non-viral carrier for tumor-targeted gene delivery. Biomaterials 28(3):540-549. (Pubitemid 44602231)
3. Changsan N, Chan HK, Separovic F, Srichana T. 2009. Physicochemical characterization and stability of rifampicin liposome dry powder formulations for inhalation. J Pharm Sci 98(2):628-639.
4. Crosasso P, Ceruti M, Brusa P, Arpicco S, Dosio F, Cattel L. 2000. Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes. J Control Release 63(1-2):19-30. (Pubitemid 30046939)
5. Domenech O, Francius G, Tulkens PM, Van Bambeke F, Dufrene Y, Mingeot-Leclercq MP. 2009. Interactions of oritavancin, a new lipoglycopeptide derived from vancomycin, with phospholipid bilayers: Effect on membrane permeability and nanoscale lipid membrane organization. Biochem Biophys Acta 1788(9):1832-1840.
6. Gregoriadis G, Davis C. 1979. Stability of liposomes in vivo and in vitro is promoted by their cholesterol content and the presence of blood cells. Biochem Biophys Res Commun 89(4):1287-1293.
7. Inoue J, Ideue R, Takahashi D, Kubota M, Kumazawa Y. 2009. Liposomal glycosphingolipids activate natural killer T cell-mediated immune responses through the endosomal pathway. J Control Release 133(1):18-23.
8. Kirby C, Clarke J, Gregoriadis G. 1980. Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro. Biochem J 186(2):591-598.
9. Klibanov AL, Maruyama K, Torchilin VP, Huang L. 1990. Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett 268(1):235-237. (Pubitemid 20233874)
10. Liu SC, O'Brien DF. 2002. Stable polymeric nanoballoons: Lyophilization and rehydration of cross-linked liposomes. J Am Chem Soc 124(21):6037-6042.
11. Liang XF, Wang HJ, Tian H, Luo H, Chang J. 2008a. Synthesis, structure and properties of novel quaternized carboxymethyl chitosan with drug loading capacity. Acta Phys Chim Sin 24(2):223-229.
12. Liang XF, Wang HJ, Luo H, Tian H, Zhang BB, Hao LJ, Teng JI, Chang J. 2008b. Characterization of novel multifunctional cationic polymeric liposomes formed from octadecyl quaternized carboxymethyl chitosan/cholesterol and drug encapsulation. Langmuir 24(14):7147-7153.
13. Mao SR, Shuai XT, Unger F, Wittmar M, Xie XL, Kissel T. 2005. Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers. Biomaterials 26(32):6343-6356. (Pubitemid 40828390)
14. Meyer O, Kirpotin D, Hong KL, Sternberg B, Park JW, Woodle MC, Papahadjopoulos D. 1998. Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides. J Biol Chem 273(25):15621-15627. (Pubitemid 28298176)
15. Mori A, Klibanov AL, Torchilin VP, Huang L. 1991. Influence of the steric barrier activity of amphipathic poly(ethyleneglycol) and ganglioside GM1 on the circulation time of liposomes and on the target binding of immunoliposomes in vivo. FEBS Lett 284(2):263-266.
16. Mu XM, Zhong ZS. 2006. Preparation and properties of poly(vinyl alcohol)-stabilized liposomes. Int J Pharm 318(1-2):55-61. (Pubitemid 43963300)
17. Sakai H, Tomiyama K, Sou K, Takeoka S, Tsuchida E. 2000. Poly(ethylene glycol)-conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state. Bioconjug Chem 11(3):425-432. (Pubitemid 30324910)
18. Sroda K, Michalak K, Maniewska J, Grynkiewicz G, Szeja W, Zawisza J, Hendrich AB. 2008. Genistein derivatives decrease liposome membrane integrity - Calcein release and molecular modeling study. Biophys Chem 138(3):78-82.
19. Weinstein JN, Yoshikami S, Henkart P, Blumenthal R, Hagins WA. 1977. Liposome-cell interaction: Transfer and intracellular release of a trapped fluorescent marker. Science 195(4277):489-492. (Pubitemid 8026868)
20. Xu QG, Tanaka Y, Czernuszka JT. 2007. Encapsulation and release of a hydrophobic drug from hydroxyapatite coated liposomes. Biomaterials 28(16):2687-2694. (Pubitemid 46367221)