-
1
-
-
33748935930
-
Dermatologic side effects associated with the epidermal growth factor receptor inhibitors
-
Agero A., Dusza S.W., Benvenuto-Andrade C., Busam K.J., Myskowski P., Halpern A.C. Dermatologic side effects associated with the epidermal growth factor receptor inhibitors. Journal of the American Academy of Dermatology 2006, 55:657-670.
-
(2006)
Journal of the American Academy of Dermatology
, vol.55
, pp. 657-670
-
-
Agero, A.1
Dusza, S.W.2
Benvenuto-Andrade, C.3
Busam, K.J.4
Myskowski, P.5
Halpern, A.C.6
-
2
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado R.G., Wolf M., Peeters M., Van Cutsem E., Siena S., Freeman D.J., Juan T., Sikorski R., Suggs S., Radinsky R., Patterson S.D., Chang D.D. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. Journal of Clinical Oncology 2008, 26:1626-1634.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
Van Cutsem, E.4
Siena, S.5
Freeman, D.J.6
Juan, T.7
Sikorski, R.8
Suggs, S.9
Radinsky, R.10
Patterson, S.D.11
Chang, D.D.12
-
3
-
-
34547591852
-
Ocular toxicities of epidermal growth factor receptor inhibitors and their management
-
Basti S. Ocular toxicities of epidermal growth factor receptor inhibitors and their management. Cancer Nursing 2007, 30:S10-S16.
-
(2007)
Cancer Nursing
, vol.30
-
-
Basti, S.1
-
4
-
-
34047248571
-
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
Benvenuti S., Sartore-Bianchi A., Di Nicolantonio F., Zanon C., Moroni M., Veronese S., Siena S., Bardelli A. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Research 2007, 67:2643-2648.
-
(2007)
Cancer Research
, vol.67
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Zanon, C.4
Moroni, M.5
Veronese, S.6
Siena, S.7
Bardelli, A.8
-
5
-
-
36949039745
-
Predictive value of skin toxicity severity for response to panitumumab in patients with metastatic colorectal cancer (mCRC): a pooled analysis of five clinical trials
-
(abstr 4134)
-
Berlin J., Van Cutsem E., Peeters M., Hecht J.R., Ruiz R., Wolf M., Amado R.G., Meropol N.J. Predictive value of skin toxicity severity for response to panitumumab in patients with metastatic colorectal cancer (mCRC): a pooled analysis of five clinical trials. Journal of Clinical Oncology 2007, 25:18s. (abstr 4134).
-
(2007)
Journal of Clinical Oncology
, vol.25
-
-
Berlin, J.1
Van Cutsem, E.2
Peeters, M.3
Hecht, J.R.4
Ruiz, R.5
Wolf, M.6
Amado, R.G.7
Meropol, N.J.8
-
6
-
-
77955663704
-
-
August 17-21, EGFR-Inhibitors induced skin reactions. Presented at the International Society of Nurses in Cancer Care Conference, Singapore, China.
-
Boers-Doets, C., Ouwerkerk, J., August 17-21, 2008. EGFR-Inhibitors induced skin reactions. Presented at the International Society of Nurses in Cancer Care Conference, Singapore, China.
-
(2008)
-
-
Boers-Doets, C.1
Ouwerkerk, J.2
-
7
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C., Bondarenko I., Makhson A., Hartmann J.T., Aparicio J., de Braud F., Donea S., Ludwig H., Schuch G., Stroh C., Loos A.H., Zubel A., Koralewski P. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. Journal of Clinical Oncology 2009, 27:663-671.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
Hartmann, J.T.4
Aparicio, J.5
de Braud, F.6
Donea, S.7
Ludwig, H.8
Schuch, G.9
Stroh, C.10
Loos, A.H.11
Zubel, A.12
Koralewski, P.13
-
8
-
-
38549142436
-
Impact and management of skin toxicity associated with anti-epidermal growth factor receptor therapy: survey results
-
Boone S.L., Rademaker A., Liu D., Pfeiffer C., Mauro D.J., Lacouture M.E. Impact and management of skin toxicity associated with anti-epidermal growth factor receptor therapy: survey results. Oncology 2007, 72:152-159.
-
(2007)
Oncology
, vol.72
, pp. 152-159
-
-
Boone, S.L.1
Rademaker, A.2
Liu, D.3
Pfeiffer, C.4
Mauro, D.J.5
Lacouture, M.E.6
-
9
-
-
27144459674
-
Trichomegaly of the eyelashes following treatment with cetuximab
-
Bouche O., Brixi-Benmansour H., Bertin A., Perceau G., Lagarde S. Trichomegaly of the eyelashes following treatment with cetuximab. Annals of Oncology 2005, 16:1711-1712.
-
(2005)
Annals of Oncology
, vol.16
, pp. 1711-1712
-
-
Bouche, O.1
Brixi-Benmansour, H.2
Bertin, A.3
Perceau, G.4
Lagarde, S.5
-
10
-
-
66749143119
-
NCCN Task Force Report: management of dermatologic and other toxicities associated with EGFR inhibition in patients with cancer
-
quiz S22-S24
-
Burtness B., Anadkat M., Basti S., Hughes M., Lacouture M.E., McClure J.S., Myskowski P.L., Paul J., Perlis C.S., Saltz L., Spencer S. NCCN Task Force Report: management of dermatologic and other toxicities associated with EGFR inhibition in patients with cancer. Journal of the National Comprehensive Cancer Network 2009, 7(Suppl. 1):S5-S21. quiz S22-S24.
-
(2009)
Journal of the National Comprehensive Cancer Network
, vol.7
, Issue.SUPPL. 1
-
-
Burtness, B.1
Anadkat, M.2
Basti, S.3
Hughes, M.4
Lacouture, M.E.5
McClure, J.S.6
Myskowski, P.L.7
Paul, J.8
Perlis, C.S.9
Saltz, L.10
Spencer, S.11
-
11
-
-
34249732333
-
Hypomagnesemia in patients with stage IV colorectal cancer treated with cetuximab as a single agent
-
(abstr 3655)
-
Carson E.J., Novak A.M., Stella P.J. Hypomagnesemia in patients with stage IV colorectal cancer treated with cetuximab as a single agent. Journal of Clinical Oncology 2005, 23(Suppl. 16s). (abstr 3655).
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.SUPPL. 16S
-
-
Carson, E.J.1
Novak, A.M.2
Stella, P.J.3
-
12
-
-
20144381957
-
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
-
Chung K.Y., Shia J., Kemeny N.E., Shah M., Schwartz G.K., Tse A., Hamilton A., Pan D., Schrag D., Schwartz L., Klimstra D.S., Fridman D., Kelsen D.P., Saltz L.B. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. Journal of Clinical Oncology 2005, 23:1803-1810.
-
(2005)
Journal of Clinical Oncology
, vol.23
, pp. 1803-1810
-
-
Chung, K.Y.1
Shia, J.2
Kemeny, N.E.3
Shah, M.4
Schwartz, G.K.5
Tse, A.6
Hamilton, A.7
Pan, D.8
Schrag, D.9
Schwartz, L.10
Klimstra, D.S.11
Fridman, D.12
Kelsen, D.P.13
Saltz, L.B.14
-
14
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D., Humblet Y., Siena S., Khayat D., Bleiberg H., Santoro A., Bets D., Mueser M., Harstrick A., Verslype C., Chau I., Van Cutsem E. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. New England Journal of Medicine 2004, 351:337-345.
-
(2004)
New England Journal of Medicine
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
15
-
-
28244440281
-
Managing cutaneous side effects of epidermal growth factor receptor (HER2/EGFR) inhibitors
-
Dick S.E., Crawford G.H. Managing cutaneous side effects of epidermal growth factor receptor (HER2/EGFR) inhibitors. Community Oncology 2005, 2:492-496.
-
(2005)
Community Oncology
, vol.2
, pp. 492-496
-
-
Dick, S.E.1
Crawford, G.H.2
-
16
-
-
34247278727
-
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by cetuximab plus chemotherapy
-
Di Fiore F., Blanchard F., Charbonnier F., Le Pessot F., Lamy A., Galais M.P., Bastit L., Killian A., Sesboüé R., Tuech J.J., Queuniet A.M., Paillot B., Sabourin J.C., Michot F., Michel P., Frebourg T. Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by cetuximab plus chemotherapy. British Journal of Cancer 2007, 96:1166-1169.
-
(2007)
British Journal of Cancer
, vol.96
, pp. 1166-1169
-
-
Di Fiore, F.1
Blanchard, F.2
Charbonnier, F.3
Le Pessot, F.4
Lamy, A.5
Galais, M.P.6
Bastit, L.7
Killian, A.8
Sesboüé, R.9
Tuech, J.J.10
Queuniet, A.M.11
Paillot, B.12
Sabourin, J.C.13
Michot, F.14
Michel, P.15
Frebourg, T.16
-
17
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as the first-line treatment for metastatic colorectal cancer. A multicentre randomised trial
-
Douillard J.Y., Cunningham D., Roth A.D., Navarro M., James R.D., Karasek P., Jandik P., Iveson T., Carmichael J., Alakl M., Gruia G., Awad L., Rougier P. Irinotecan combined with fluorouracil compared with fluorouracil alone as the first-line treatment for metastatic colorectal cancer. A multicentre randomised trial. Lancet 2000, 355:1041-1047.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
18
-
-
33750199017
-
Ocular toxicity related to cetuximab monotherapy in patients with colorectal cancer
-
Dranko S., Kinney C., Ramanathan R.K. Ocular toxicity related to cetuximab monotherapy in patients with colorectal cancer. Clinical Colorectal Cancer 2006, 6:224-225.
-
(2006)
Clinical Colorectal Cancer
, vol.6
, pp. 224-225
-
-
Dranko, S.1
Kinney, C.2
Ramanathan, R.K.3
-
19
-
-
0038163630
-
Epidermal growth factor receptor inhibitor induces trichomegaly
-
Dueland S., Sauer T., Lund-Johansen F., Ostenstad B., Tveit K.M. Epidermal growth factor receptor inhibitor induces trichomegaly. Acta Oncology 2003, 42:345-346.
-
(2003)
Acta Oncology
, vol.42
, pp. 345-346
-
-
Dueland, S.1
Sauer, T.2
Lund-Johansen, F.3
Ostenstad, B.4
Tveit, K.M.5
-
20
-
-
69249232886
-
-
Available from:, Bristol-Meyers Squbb, Branchburg, NJ, (accessed 9 July 2009)
-
Erbitux (Cetuximab) Prescribing Information 2008, Available from:, Bristol-Meyers Squbb, Branchburg, NJ, (accessed 9 July 2009). http://packageinserts.bms.com/pi/pi_erbitux.pdf.
-
(2008)
Erbitux (Cetuximab) Prescribing Information
-
-
-
21
-
-
33748675101
-
-
Merck KGaA, Darmstadt, Germany, Available from:(accessed 11 November 2008)
-
Erbitux (Cetuximab) Summary of Product Characteristics 2009, Merck KGaA, Darmstadt, Germany, Available from:(accessed 11 November 2008). http://www.emea.europa.eu/humandocs/PDFs/EPAR/erbitux/H-558-PI-en.pdf.
-
(2009)
Erbitux (Cetuximab) Summary of Product Characteristics
-
-
-
22
-
-
33749034712
-
Cetuximab-induced hypomagnesaemia in patients with colorectal cancer
-
Fakih M.G., Wilding G., Lombardo J. Cetuximab-induced hypomagnesaemia in patients with colorectal cancer. Clinical Colorectal Cancer 2006, 6:152-156.
-
(2006)
Clinical Colorectal Cancer
, vol.6
, pp. 152-156
-
-
Fakih, M.G.1
Wilding, G.2
Lombardo, J.3
-
23
-
-
48249086178
-
Persisting corneal erosion under cetuximab (Erbitux) treatment (epidermal growth factor receptor antibody)
-
Foerster C.G., Cursiefen C., Kruse F.E. Persisting corneal erosion under cetuximab (Erbitux) treatment (epidermal growth factor receptor antibody). Cornea 2008, 27:612-614.
-
(2008)
Cornea
, vol.27
, pp. 612-614
-
-
Foerster, C.G.1
Cursiefen, C.2
Kruse, F.E.3
-
24
-
-
33847643669
-
Classification and management of skin, hair, nail, and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors
-
Galimont-Collen A.F.S., Vos L.E., Lavrijsen A.P.M., Ouwerkerk J., Gelderblom H. Classification and management of skin, hair, nail, and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors. European Journal of Cancer 2007, 43:845-851.
-
(2007)
European Journal of Cancer
, vol.43
, pp. 845-851
-
-
Galimont-Collen, A.F.S.1
Vos, L.E.2
Lavrijsen, A.P.M.3
Ouwerkerk, J.4
Gelderblom, H.5
-
25
-
-
77955653842
-
Updated analysis of a phase II study (20060314) of panitumumab (pmab) with FOLFIRI as first-line treatment of patients (pts) with metastatic colorectal cancer (mCRC)
-
(abstr 4085)
-
Greil R., Letocha H., Gamelin E., Thaler J., Hofheinz R., Mineur L., Thaler J., Hofheinz R., Mineur L., Fernebro E., Karthaus M., Wright L., Köhne C. Updated analysis of a phase II study (20060314) of panitumumab (pmab) with FOLFIRI as first-line treatment of patients (pts) with metastatic colorectal cancer (mCRC). Journal of Clinical Oncology 2009, 27(Suppl. 15s). (abstr 4085).
-
(2009)
Journal of Clinical Oncology
, vol.27
, Issue.SUPPL. 15S
-
-
Greil, R.1
Letocha, H.2
Gamelin, E.3
Thaler, J.4
Hofheinz, R.5
Mineur, L.6
Thaler, J.7
Hofheinz, R.8
Mineur, L.9
Fernebro, E.10
Karthaus, M.11
Wright, L.12
Köhne, C.13
-
26
-
-
34047219240
-
Recognizing and managing toxicities of molecular targeted therapies for colorectal cancer
-
Grothey A. Recognizing and managing toxicities of molecular targeted therapies for colorectal cancer. Oncology (Williston Park) 2006, 20:21-28.
-
(2006)
Oncology (Williston Park)
, vol.20
, pp. 21-28
-
-
Grothey, A.1
-
27
-
-
2142703727
-
Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
-
Grothey A., Sargent D., Goldberg R.M., Schmoll H.J. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. Journal of Clinical Oncology 2004, 22:1209-1214.
-
(2004)
Journal of Clinical Oncology
, vol.22
, pp. 1209-1214
-
-
Grothey, A.1
Sargent, D.2
Goldberg, R.M.3
Schmoll, H.J.4
-
28
-
-
77955664965
-
-
Panitumumab (pmab) efficacy in patients (pts) with metastatic colorectal cancer (mCRC) with low or undetectable levels of epidermal growth factor receptor (EGFr): final efficacy and KRAS analyses. In: Presented at the 2008 American Society of Clinical Oncology Gastrointestinal Cancers Symposium, January
-
Hecht, J., Mitchell, E.P., Baranda, J., Richards, D., Reiner, M., Stout, S., Amado, R.G., 2008. Panitumumab (pmab) efficacy in patients (pts) with metastatic colorectal cancer (mCRC) with low or undetectable levels of epidermal growth factor receptor (EGFr): final efficacy and KRAS analyses. In: Presented at the 2008 American Society of Clinical Oncology Gastrointestinal Cancers Symposium, January 25-27, 2008; Orlando, FL (abstract 343).
-
(2008)
-
-
Hecht, J.1
Mitchell, E.P.2
Baranda, J.3
Richards, D.4
Reiner, M.5
Stout, S.6
Amado, R.G.7
-
29
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H., Fehrenbacher L., Novotny W., Cartwright T., Hainsworth J., Heim W., Berlin J., Baron A., Griffing S., Holmgren E., Ferrara N., Fyfe G., Rogers B., Ross R., Kabbinavar F. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. New England Journal of Medicine 2004, 350:2335-2342.
-
(2004)
New England Journal of Medicine
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
30
-
-
50249101750
-
Tetracycline to prevent epidermal growth factor receptor inhibitor-induced skin rashes: results of a placebo-controlled trial from the North Central Cancer Treatment Group (N03CB)
-
Jatoi A., Rowland K., Sloan J.A., Gross H.M., Fishkin P.A., Kahanic S.P., Novotny P.J., Schaefer P.L., Johnson D.B., Tschetter L.K., Loprinzi C.L. Tetracycline to prevent epidermal growth factor receptor inhibitor-induced skin rashes: results of a placebo-controlled trial from the North Central Cancer Treatment Group (N03CB). Cancer 2008, 113:847-853.
-
(2008)
Cancer
, vol.113
, pp. 847-853
-
-
Jatoi, A.1
Rowland, K.2
Sloan, J.A.3
Gross, H.M.4
Fishkin, P.A.5
Kahanic, S.P.6
Novotny, P.J.7
Schaefer, P.L.8
Johnson, D.B.9
Tschetter, L.K.10
Loprinzi, C.L.11
-
31
-
-
47149084688
-
Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer
-
Jean G.W., Shah S.R. Epidermal growth factor receptor monoclonal antibodies for the treatment of metastatic colorectal cancer. Pharmacotherapy 2008, 28:742-754.
-
(2008)
Pharmacotherapy
, vol.28
, pp. 742-754
-
-
Jean, G.W.1
Shah, S.R.2
-
32
-
-
36148941301
-
Cetuximab for the treatment of colorectal cancer
-
Jonker D.J., O'Callaghan C.J., Karapetis C.S., Zalcberg J.R., Tu D., Au H.J., Berry S.R., Krahn M., Price T., Simes R.J., Tebbutt N.C., van Hazel G., Wierzbicki R., Langer C., Moore M.J. Cetuximab for the treatment of colorectal cancer. New England Journal of Medicine 2007, 357:2040-2048.
-
(2007)
New England Journal of Medicine
, vol.357
, pp. 2040-2048
-
-
Jonker, D.J.1
O'Callaghan, C.J.2
Karapetis, C.S.3
Zalcberg, J.R.4
Tu, D.5
Au, H.J.6
Berry, S.R.7
Krahn, M.8
Price, T.9
Simes, R.J.10
Tebbutt, N.C.11
van Hazel, G.12
Wierzbicki, R.13
Langer, C.14
Moore, M.J.15
-
33
-
-
35648954031
-
Infusion-related and hypersensitivity reactions of monoclonal antibodies use to treat colorectal cancer-identification, prevention, and treatment
-
Kang S.P., Saif M.W. Infusion-related and hypersensitivity reactions of monoclonal antibodies use to treat colorectal cancer-identification, prevention, and treatment. The Journal of Supportive Oncology 2007, 5:451-457.
-
(2007)
The Journal of Supportive Oncology
, vol.5
, pp. 451-457
-
-
Kang, S.P.1
Saif, M.W.2
-
34
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis C.S., Khambata-Ford S., Jonker D.J., O'Callaghan C.J., Tu D., Tebbutt N.C., Simes R.J., Chalchal H., Shapiro J.D., Robitaille S., Price T.J., Shepherd L., Au H.J., Langer C., Moore M.J., Zalcberg J.R. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. New England Journal of Medicine 2008, 359:1757-1765.
-
(2008)
New England Journal of Medicine
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
O'Callaghan, C.J.4
Tu, D.5
Tebbutt, N.C.6
Simes, R.J.7
Chalchal, H.8
Shapiro, J.D.9
Robitaille, S.10
Price, T.J.11
Shepherd, L.12
Au, H.J.13
Langer, C.14
Moore, M.J.15
Zalcberg, J.R.16
-
35
-
-
77955657545
-
-
Impact of pre-emptive skin toxicity (ST) treatment (tx) on panitumumab (pmab)-related skin toxicities and quality of life (QOL) in patients (pts) with metastatic colorectal cancer (mCRC): results from STEPP. Presented at the American Society of Clinical Oncology Gastrointestinal Cancers
-
Lacouture, M.E. Mitchell, E.P., Shearer, H., Iannotti, N., Piperdi, B., Pillai, M.V., Xu, F., Yassine, M., 2009. Impact of pre-emptive skin toxicity (ST) treatment (tx) on panitumumab (pmab)-related skin toxicities and quality of life (QOL) in patients (pts) with metastatic colorectal cancer (mCRC): results from STEPP. Presented at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium, January 15-17, 2009; San Francisco, CA (abstract 291).
-
(2009)
-
-
Lacouture, M.E.1
Mitchell, E.P.2
Shearer, H.3
Iannotti, N.4
Piperdi, B.5
Pillai, M.V.6
Xu, F.7
Yassine, M.8
-
36
-
-
34547586714
-
Insights into the pathophysiology and management of dermatologic toxicities to EGFR-targeted therapies in colorectal cancer
-
Lacouture M.E. Insights into the pathophysiology and management of dermatologic toxicities to EGFR-targeted therapies in colorectal cancer. Cancer Nursing 2007, 30:S17-S25.
-
(2007)
Cancer Nursing
, vol.30
-
-
Lacouture, M.E.1
-
37
-
-
33646810076
-
The SERIES clinic: an interdisciplinary approach to the management of toxicities of EGFR inhibitors
-
Lacouture M.E., Basti S., Patel J., Benson A. The SERIES clinic: an interdisciplinary approach to the management of toxicities of EGFR inhibitors. The Journal of Supportive Oncology 2006, 4:236-238.
-
(2006)
The Journal of Supportive Oncology
, vol.4
, pp. 236-238
-
-
Lacouture, M.E.1
Basti, S.2
Patel, J.3
Benson, A.4
-
38
-
-
37049032136
-
First-line use of anti-epidermal growth factor receptor monoclonal antibodies in metastatic colorectal cancer
-
Lee J.J., Chu E. First-line use of anti-epidermal growth factor receptor monoclonal antibodies in metastatic colorectal cancer. Clinical Colorectal Cancer 2007, 6:S42-S46.
-
(2007)
Clinical Colorectal Cancer
, vol.6
-
-
Lee, J.J.1
Chu, E.2
-
39
-
-
77955652992
-
-
Personalised cancer therapy: what is KRAS and what does it mean for patients with metastatic colorectal cancer? EONS Newsletter. Fall
-
Lemmens, L., 2008. Personalised cancer therapy: what is KRAS and what does it mean for patients with metastatic colorectal cancer? EONS Newsletter. Fall, 28-31.
-
(2008)
, pp. 28-31
-
-
Lemmens, L.1
-
40
-
-
33750615769
-
Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines
-
Lenz H.J., Van Cutsem E., Khambata-Ford S., Mayer R.J., Gold P., Stella P., Mirtsching B., Cohn A.L., Pippas A.W., Azarnia N., Tsuchihashi Z., Mauro D.J., Rowinsky E.K. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. Journal of Clinical Oncology 2006, 24:4914-4921.
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. 4914-4921
-
-
Lenz, H.J.1
Van Cutsem, E.2
Khambata-Ford, S.3
Mayer, R.J.4
Gold, P.5
Stella, P.6
Mirtsching, B.7
Cohn, A.L.8
Pippas, A.W.9
Azarnia, N.10
Tsuchihashi, Z.11
Mauro, D.J.12
Rowinsky, E.K.13
-
41
-
-
38649099966
-
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
-
Lievre A., Bachet J.B., Boige V., Cayre A., Le Corre D., Buc E., Ychou M., Bouché O., Landi B., Louvet C., André T., Bibeau F., Diebold M.D., Rougier P., Ducreux M., Tomasic G., Emile J.F., Penault-Llorca F., Laurent-Puig P. KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. Journal of Clinical Oncology 2008, 26:374-379.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 374-379
-
-
Lievre, A.1
Bachet, J.B.2
Boige, V.3
Cayre, A.4
Le Corre, D.5
Buc, E.6
Ychou, M.7
Bouché, O.8
Landi, B.9
Louvet, C.10
André, T.11
Bibeau, F.12
Diebold, M.D.13
Rougier, P.14
Ducreux, M.15
Tomasic, G.16
Emile, J.F.17
Penault-Llorca, F.18
Laurent-Puig, P.19
-
42
-
-
35548969264
-
Epidermal growth factor receptor inhibitor-associated cutaneous toxicities: an evolving paradigm in clinical management
-
Lynch T.J., Kim E.S., Eaby B., Garey J., West D.P., Lacouture M.E. Epidermal growth factor receptor inhibitor-associated cutaneous toxicities: an evolving paradigm in clinical management. Oncologist 2007, 12:610-621.
-
(2007)
Oncologist
, vol.12
, pp. 610-621
-
-
Lynch, T.J.1
Kim, E.S.2
Eaby, B.3
Garey, J.4
West, D.P.5
Lacouture, M.E.6
-
43
-
-
65749101493
-
Management of skin rash during EGFR-targeted monoclonal antibody treatment for gastrointestinal malignancies: Canadian recommendations
-
Melosky B., Burkes R., Rayson D., Alcindor T., Shear N., Lacouture M. Management of skin rash during EGFR-targeted monoclonal antibody treatment for gastrointestinal malignancies: Canadian recommendations. Current Oncology 2009, 16:16-26.
-
(2009)
Current Oncology
, vol.16
, pp. 16-26
-
-
Melosky, B.1
Burkes, R.2
Rayson, D.3
Alcindor, T.4
Shear, N.5
Lacouture, M.6
-
44
-
-
12344312699
-
-
National Cancer Institute, Available from:(accessed November 15, 2009)
-
Common Toxicity Criteria for Adverse Events (CTCAE) Version 4.0 2009, National Cancer Institute, Available from:(accessed November 15, 2009). http://ctep.cancer.gov/protocoldevelopment/electronic_applications/docs/ctcaev4.pdf.
-
(2009)
Common Toxicity Criteria for Adverse Events (CTCAE) Version 4.0
-
-
-
45
-
-
38849178281
-
Clinical approaches to minimize rash associated with EGFR inhibitors
-
Oishi K. Clinical approaches to minimize rash associated with EGFR inhibitors. Oncology Nursing Forum 2008, 35:103-111.
-
(2008)
Oncology Nursing Forum
, vol.35
, pp. 103-111
-
-
Oishi, K.1
-
46
-
-
55249110754
-
Phase III study (20050181) of panitumumab (pmab) with FOLFIRI versus FOLFIRI alone as second-line treatment (tx) in patients (pts) with metastatic colorectal cancer (mCRC): pooled safety results
-
(abstr 4064)
-
Peeters M., Wilson G., Ducreux M., Cervantes A., André T., Hotko Y., Lordick F., Collins S., Shing M., Price T.J. Phase III study (20050181) of panitumumab (pmab) with FOLFIRI versus FOLFIRI alone as second-line treatment (tx) in patients (pts) with metastatic colorectal cancer (mCRC): pooled safety results. Journal of Clinical Oncology 2008, 26(Suppl. 15s). (abstr 4064).
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.SUPPL. 15S
-
-
Peeters, M.1
Wilson, G.2
Ducreux, M.3
Cervantes, A.4
André, T.5
Hotko, Y.6
Lordick, F.7
Collins, S.8
Shing, M.9
Price, T.J.10
-
47
-
-
20844448897
-
HER1/EGFR inhibitor-associated rash: future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum
-
Perez-Soler R., Delord J.P., Halpern A., Kelly K., Krueger J., Sureda B.M., von Pawel J., Temel J., Siena S., Soulières D., Saltz L., Leyden J. HER1/EGFR inhibitor-associated rash: future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum. Oncologist 2005, 10:345-356.
-
(2005)
Oncologist
, vol.10
, pp. 345-356
-
-
Perez-Soler, R.1
Delord, J.P.2
Halpern, A.3
Kelly, K.4
Krueger, J.5
Sureda, B.M.6
von Pawel, J.7
Temel, J.8
Siena, S.9
Soulières, D.10
Saltz, L.11
Leyden, J.12
-
48
-
-
24644513947
-
Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining?
-
Peréz-Soler R., Saltz L. Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining?. Journal of Clinical Oncology 2005, 23:5235-5246.
-
(2005)
Journal of Clinical Oncology
, vol.23
, pp. 5235-5246
-
-
Peréz-Soler, R.1
Saltz, L.2
-
49
-
-
45549086789
-
Targeting metastatic colorectal cancer in 2008: a long way from 5-FU
-
Pohl A., Zhang W., Ning Y., Manegold P.C., Lurje G., Lenz H.-J. Targeting metastatic colorectal cancer in 2008: a long way from 5-FU. Oncology 2008, 22:456-462.
-
(2008)
Oncology
, vol.22
, pp. 456-462
-
-
Pohl, A.1
Zhang, W.2
Ning, Y.3
Manegold, P.C.4
Lurje, G.5
Lenz, H.-J.6
-
50
-
-
4544368057
-
Understanding and managing chemotherapy-induced diarrhea
-
Saltz L.B. Understanding and managing chemotherapy-induced diarrhea. The Journal of Supportive Oncology 2003, 1:35-46.
-
(2003)
The Journal of Supportive Oncology
, vol.1
, pp. 35-46
-
-
Saltz, L.B.1
-
51
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Saltz L.B., Cox J.V., Blanke C., Rosen L.S., Fehrenbacher L., Moore M.J., Maroun J.A., Ackland S.P., Locker P.K., Pirotta N., Elfring G.L., Miller L.L. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. New England Journal of Medicine 2000, 343:905-914.
-
(2000)
New England Journal of Medicine
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
Rosen, L.S.4
Fehrenbacher, L.5
Moore, M.J.6
Maroun, J.A.7
Ackland, S.P.8
Locker, P.K.9
Pirotta, N.10
Elfring, G.L.11
Miller, L.L.12
-
52
-
-
35648941728
-
Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in the irinotecan-refractory colorectal cancer
-
Saltz L.B., Lenz H.J., Kindler H.L., Hochster H.S., Wadler S., Hoff P.M., Kemeny N.E., Hollywood E.M., Gonen M., Quinones M., Morse M., Chen H.X. Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in the irinotecan-refractory colorectal cancer. Journal of Clinical Oncology 2007, 25:4557-4561.
-
(2007)
Journal of Clinical Oncology
, vol.25
, pp. 4557-4561
-
-
Saltz, L.B.1
Lenz, H.J.2
Kindler, H.L.3
Hochster, H.S.4
Wadler, S.5
Hoff, P.M.6
Kemeny, N.E.7
Hollywood, E.M.8
Gonen, M.9
Quinones, M.10
Morse, M.11
Chen, H.X.12
-
53
-
-
2142641698
-
Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
-
Saltz L.B., Meropol N.J., Loehrer P.J., Needle M.N., Kopit J., Mayer R.J. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J. Clin. Oncol 2004, 22:1201-1208.
-
(2004)
J. Clin. Oncol
, vol.22
, pp. 1201-1208
-
-
Saltz, L.B.1
Meropol, N.J.2
Loehrer, P.J.3
Needle, M.N.4
Kopit, J.5
Mayer, R.J.6
-
54
-
-
23844555670
-
Cetuximab therapy and symptomatic hypomagnesemia
-
Schrag D., Chung K.Y., Flombaum C., Saltz L. Cetuximab therapy and symptomatic hypomagnesemia. Journal of National Cancer Institute 2005, 97:1221-1224.
-
(2005)
Journal of National Cancer Institute
, vol.97
, pp. 1221-1224
-
-
Schrag, D.1
Chung, K.Y.2
Flombaum, C.3
Saltz, L.4
-
55
-
-
36849093857
-
Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption
-
Scope A., Agero A.L., Dusza S.W., Myskowski P.L., Lieb J.A., Saltz L., Kemeny N.E., Halpern A.C. Randomized double-blind trial of prophylactic oral minocycline and topical tazarotene for cetuximab-associated acne-like eruption. Journal of Clinical Oncology 2007, 25:5390-5396.
-
(2007)
Journal of Clinical Oncology
, vol.25
, pp. 5390-5396
-
-
Scope, A.1
Agero, A.L.2
Dusza, S.W.3
Myskowski, P.L.4
Lieb, J.A.5
Saltz, L.6
Kemeny, N.E.7
Halpern, A.C.8
-
56
-
-
70349091806
-
Skin toxicities of targeted therapies
-
Segaert S., Chiritescu G., Lemmens L., Dumon K., Van Cutsem E., Tejpar S. Skin toxicities of targeted therapies. European Journal of Cancer 2009, 45(Suppl. 1):295-308.
-
(2009)
European Journal of Cancer
, vol.45
, Issue.SUPPL. 1
, pp. 295-308
-
-
Segaert, S.1
Chiritescu, G.2
Lemmens, L.3
Dumon, K.4
Van Cutsem, E.5
Tejpar, S.6
-
57
-
-
70349939382
-
Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
-
Siena S., Sartore-Bianchi A., Di Nicolantonio F., Balfour J., Bardelli A. Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. Journal of National Cancer Institute 2009, 101:1308-1324.
-
(2009)
Journal of National Cancer Institute
, vol.101
, pp. 1308-1324
-
-
Siena, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Balfour, J.4
Bardelli, A.5
-
58
-
-
57149101253
-
Phase III study (PRIME/20050203) of panitumumab (pmab) with FOLFOX compared with FOLFOX alone in patients (pts) with previously untreated metastatic colorectal cancer (mCRC): pooled safety data
-
(abstr 4034)
-
Siena S., Tabernero J., Burkes R.L., Cassidy J., Cunningham D., Barugel M.E., Humblet Y., McPhie C., Shing M., Douillard J. Phase III study (PRIME/20050203) of panitumumab (pmab) with FOLFOX compared with FOLFOX alone in patients (pts) with previously untreated metastatic colorectal cancer (mCRC): pooled safety data. Journal of Clinical Oncology 2008, 26(Suppl. 15s). (abstr 4034).
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.SUPPL. 15S
-
-
Siena, S.1
Tabernero, J.2
Burkes, R.L.3
Cassidy, J.4
Cunningham, D.5
Barugel, M.E.6
Humblet, Y.7
McPhie, C.8
Shing, M.9
Douillard, J.10
-
59
-
-
33645785843
-
Common side effects of anti-EGFR therapy: acneform rash
-
Sipples R. Common side effects of anti-EGFR therapy: acneform rash. Seminars in Oncology Nursing 2006, 22:28-34.
-
(2006)
Seminars in Oncology Nursing
, vol.22
, pp. 28-34
-
-
Sipples, R.1
-
60
-
-
44249111440
-
EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer
-
Sobrero A.F., Maurel J., Fehrenbacher L., Scheithauer W., Abubakr Y.A., Lutz M.P., Vega-Villegas M.E., Eng C., Steinhauer E.U., Prausova J., Lenz H.J., Borg C., Middleton G., Kröning H., Luppi G., Kisker O., Zubel A., Langer C., Kopit J., Burris H.A. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. Journal of Clinical Oncology 2008, 26:2311-2319.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 2311-2319
-
-
Sobrero, A.F.1
Maurel, J.2
Fehrenbacher, L.3
Scheithauer, W.4
Abubakr, Y.A.5
Lutz, M.P.6
Vega-Villegas, M.E.7
Eng, C.8
Steinhauer, E.U.9
Prausova, J.10
Lenz, H.J.11
Borg, C.12
Middleton, G.13
Kröning, H.14
Luppi, G.15
Kisker, O.16
Zubel, A.17
Langer, C.18
Kopit, J.19
Burris, H.A.20
more..
-
61
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer. A randomized GERCOR study
-
Tournigand C., Andre T., Achille E., Lledo G., Flesh M., Mery-Mignard D., Quinaux E., Couteau C., Buyse M., Ganem G., Landi B., Colin P., Louvet C., de Gramont A. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer. A randomized GERCOR study. Journal of Clinical Oncology 2004, 22:229-237.
-
(2004)
Journal of Clinical Oncology
, vol.22
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
Lledo, G.4
Flesh, M.5
Mery-Mignard, D.6
Quinaux, E.7
Couteau, C.8
Buyse, M.9
Ganem, G.10
Landi, B.11
Colin, P.12
Louvet, C.13
de Gramont, A.14
-
62
-
-
62449226157
-
Trichomegaly of the eyelashes following treatment with cetuximab
-
Vaccaro M., Pollicino A., Barbuzza O., Guarneri B. Trichomegaly of the eyelashes following treatment with cetuximab. Clinical and Experimental Dermatology 2009, 34:402-403.
-
(2009)
Clinical and Experimental Dermatology
, vol.34
, pp. 402-403
-
-
Vaccaro, M.1
Pollicino, A.2
Barbuzza, O.3
Guarneri, B.4
-
63
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E., Köhne C.H., Hitre E., Zaluski J., Chang Chien C.R., Makhson A., D'Haens G., Pintér T., Lim R., Bodoky G., Roh J.K., Folprecht G., Ruff P., Stroh C., Tejpar S., Schlichting M., Nippgen J., Rougier P. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. New England Journal of Medicine 2009, 360:1408-1417.
-
(2009)
New England Journal of Medicine
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
Zaluski, J.4
Chang Chien, C.R.5
Makhson, A.6
D'Haens, G.7
Pintér, T.8
Lim, R.9
Bodoky, G.10
Roh, J.K.11
Folprecht, G.12
Ruff, P.13
Stroh, C.14
Tejpar, S.15
Schlichting, M.16
Nippgen, J.17
Rougier, P.18
-
64
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
-
Van Cutsem E., Peeters M., Siena S., Humblet Y., Hendlisz A., Neyns B., Canon J.L., Van Laethem J.L., Maurel J., Richardson G., Wolf M., Amado R.G. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. Journal of Clinical Oncology 2007, 25:1658-1664.
-
(2007)
Journal of Clinical Oncology
, vol.25
, pp. 1658-1664
-
-
Van Cutsem, E.1
Peeters, M.2
Siena, S.3
Humblet, Y.4
Hendlisz, A.5
Neyns, B.6
Canon, J.L.7
Van Laethem, J.L.8
Maurel, J.9
Richardson, G.10
Wolf, M.11
Amado, R.G.12
-
66
-
-
65549089387
-
-
Available from:, Amgen, Inc., Thousand Oaks, CA, (accessed 9 July 2009)
-
Vectibix (Panitumumab) Prescribing Information 2008, Available from:, Amgen, Inc., Thousand Oaks, CA, (accessed 9 July 2009). http://www.vectibix.com/pdfs/misc/vectibix_pi.pdf.
-
(2008)
Vectibix (Panitumumab) Prescribing Information
-
-
-
67
-
-
77952118055
-
-
Available from:, Amgen Europe BV, Breda, The Netherlands, (accessed 11 November 2008)
-
Vectibix (Panitumumab) Summary of Product Characteristics 2009, Available from:, Amgen Europe BV, Breda, The Netherlands, (accessed 11 November 2008). http://www.emea.europa.eu/humandocs/PDFs/EPAR/vectibix/H-741-PI-en.pdf.
-
(2009)
Vectibix (Panitumumab) Summary of Product Characteristics
-
-
-
68
-
-
33751085911
-
Nursing care of patients receiving chemotherapy for metastatic colorectal cancer: implications of the treatment continuum concept
-
Viale P.H., Sommers R. Nursing care of patients receiving chemotherapy for metastatic colorectal cancer: implications of the treatment continuum concept. Seminars in Oncology Nursing 2007, 23:22-35.
-
(2007)
Seminars in Oncology Nursing
, vol.23
, pp. 22-35
-
-
Viale, P.H.1
Sommers, R.2
-
69
-
-
45349097237
-
Panitumumab: human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer
-
Wu M., Rivkin A., Pham T. Panitumumab: human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer. Clinical Therapeutics 2008, 30:14-30.
-
(2008)
Clinical Therapeutics
, vol.30
, pp. 14-30
-
-
Wu, M.1
Rivkin, A.2
Pham, T.3
-
70
-
-
34547668744
-
Acquired trichomegaly and symptomatic external ocular changes in patients receiving epidermal growth factor receptor inhibitors: case reports and a review of the literature
-
Zhang G., Basti S., Jampol L.M. Acquired trichomegaly and symptomatic external ocular changes in patients receiving epidermal growth factor receptor inhibitors: case reports and a review of the literature. Cornea 2007, 26:858-860.
-
(2007)
Cornea
, vol.26
, pp. 858-860
-
-
Zhang, G.1
Basti, S.2
Jampol, L.M.3
-
71
-
-
33847124958
-
Novel approaches to treatment of advanced colorectal cancer with anti-EGFR monoclonal antibodies
-
Zhang W., Gordon M., Lenz H.J. Novel approaches to treatment of advanced colorectal cancer with anti-EGFR monoclonal antibodies. Annals of Medicine 2006, 38:545-551.
-
(2006)
Annals of Medicine
, vol.38
, pp. 545-551
-
-
Zhang, W.1
Gordon, M.2
Lenz, H.J.3
-
72
-
-
42449147858
-
Systemic therapy for metastatic colorectal cancer: current questions
-
Zuckerman D.S., Clark J.W. Systemic therapy for metastatic colorectal cancer: current questions. Cancer 2008, 112:1879-1891.
-
(2008)
Cancer
, vol.112
, pp. 1879-1891
-
-
Zuckerman, D.S.1
Clark, J.W.2
|