The synthesis and structure-activity relationship of 4-benzimidazolyl- piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 17, 2010, Pages 5004-5008

  Ting, Pauline C ^a   Lee, Joe F ^a   Albanese, Margaret M ^a   Wu, Jie ^a   Aslanian, Robert ^a   Favreau, Leonard ^a   Nardo, Cymbelene ^a   Korfmacher, Walter A ^a   West, Robert E ^a   Williams, Shirley M ^a   Anthes, John C ^a   Rivelli, Maria A ^a   Corboz, Michel R ^a   Hey, John A ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b CoMentis ^*  (United States)

Author keywords

Histamine H3 antagonist

Indexed keywords

4 BENZIMIDAZOLYL PIPERIDINYLCARBONYL PIPERIDINE DERIVATIVE; 4 PYRIDYLCARBOXALDEHYDE; HISTAMINE H3 RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG SYNTHESIS; IN VIVO STUDY; STRUCTURE ACTIVITY RELATION;

HISTAMINE H3 ANTAGONISTS; PIPERIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77955660320     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.07.052     Document Type: Article

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