GnRH-induced PACAP and PAC1 receptor expression in pituitary gonadotrophs: A possible role in the regulation of gonadotropin subunit gene expression

Peptides

Volumn 31, Issue 9, 2010, Pages 1748-1755

  Purwana, Indri N ^a   Kanasaki, Haruhiko ^a   Oride, Aki ^a   Mijiddorj, Tselmeg ^a   Shintani, Norihito ^b   Hashimoto, Hitoshi ^b   Baba, Akemichi ^b   Miyazaki, Kohji ^a  

^a SHIMANE UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

GnRH; Gonadotropin; PACAP

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE 2; FOLLITROPIN BETA SUBUNIT; GONADORELIN; GONADOTROPIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS HORMONE; LUTEINIZING HORMONE BETA SUBUNIT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RECEPTOR SUBTYPE;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EXPRESSION VECTOR; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GONADOTROPIN SECRETING CELL; HYPOPHYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURFACE PROPERTY;

ANIMALS; CELL LINE; CELL MEMBRANE; CYCLIC AMP; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FOLLICLE STIMULATING HORMONE, BETA SUBUNIT; GENE EXPRESSION REGULATION; GENES, REPORTER; GONADOTROPHS; GONADOTROPIN-RELEASING HORMONE; GONADOTROPINS, PITUITARY; LUTEINIZING HORMONE, BETA SUBUNIT; MICE; PHOSPHORYLATION; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PROMOTER REGIONS, GENETIC; PROTEIN SUBUNITS; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; RNA, MESSENGER; SURFACE PROPERTIES; TIME FACTORS;

EID: 77955657424     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.05.012     Document Type: Article

References (51)

1. G.Y. Bedecarrats, and U.B. Kaiser Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration Endocrinology 144 2003 1802 1811
2. L.L. Burger, A.C. Dalkin, K.W. Aylor, D.J. Haisenleder, and J.C. Marshall GnRH pulse frequency modulation of gonadotropin subunit gene transcription in normal gonadotropes-assessment by primary transcript assay provides evidence for roles of GnRH and follistatin Endocrinology 143 2002 3243 3249
3. J.M. Burrin, S.J. Aylwin, J.G. Holdstock, and U. Sahye Mechanism of action of pituitary adenylate cyclase-activating polypeptide on human glycoprotein hormone alpha-subunit transcription in alphaT3-1 gonadotropes Endocrinology 139 1998 1731 1737
4. B.M. Cattanach, C.A. Iddon, H.M. Charlton, S.A. Chiappa, and G. Fink Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism Nature 269 1977 338 340
5. R. Counis, J.N. Laverriere, G. Garrel-Lazayres, J. Cohen-Tannoudji, S. Lariviere, and C. Bleux What is the role of PACAP in gonadotrope function? Peptides 28 2007 1797 1804
6. M.D. Culler, and C.S. Paschall Pituitary adenylate cyclase-activating polypeptide (PACAP) potentiates the gonadotropin-releasing activity of luteinizing hormone-releasing hormone Endocrinology 129 1991 2260 2262
7. A.C. Dalkin, D.J. Haisenleder, J.T. Gilrain, K. Aylor, M. Yasin, and J.C. Marshall Regulation of pituitary follistatin and inhibin/activin subunit messenger ribonucleic acids (mRNAs) in male and female rats: evidence for inhibin regulation of follistatin mRNA in females Endocrinology 139 1998 2818 2823
8. A.C. Dalkin, D.J. Haisenleder, G.A. Ortolano, T.R. Ellis, and J.C. Marshall The frequency of gonadotropin-releasing-hormone stimulation differentially regulates gonadotropin subunit messenger ribonucleic acid expression Endocrinology 125 1989 917 924
9. L. Dickson, and K. Finlayson VPAC and PAC receptors: from ligands to function Pharmacol Ther 121 2009 294 316
10. H.A. Ferris, H.E. Walsh, J. Stevens, P.C. Fallest, and M.A. Shupnik Luteinizing hormone beta promoter stimulation by adenylyl cyclase and cooperation with gonadotropin-releasing hormone 1 in transgenic mice and LBetaT2 Cells Biol Reprod 77 2007 1073 1080
11. R.C. Fowkes, K.K. Sidhu, J.K. Sosabowski, P. King, and J.M. Burrin Absence of pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein alpha-subunit gene in LbetaT2 gonadotrophs reveals disrupted cAMP-mediated gene transcription J Mol Endocrinol 31 2003 263 278
12. C.M. Grafer, R. Thomas, L. Lambrakos, I. Montoya, S. White, and L.M. Halvorson GnRH stimulates expression of PACAP in the pituitary gonadotropes via both the PKA and PKC signaling systems Mol Endocrinol (Baltimore, Md) 23 2009 1022 1032
13. T. Harada, H. Kanasaki, S. Mutiara, A. Oride, and K. Miyazaki Cyclic adenosine 3′,5′monophosphate/protein kinase A and mitogen-activated protein kinase 3/1 pathways are involved in adenylate cyclase-activating polypeptide 1-induced common alpha-glycoprotein subunit gene (Cga) expression in mouse pituitary gonadotroph LbetaT2 cells Biol Reprod 77 2007 707 716
14. D. Harris, D. Bonfil, D. Chuderland, S. Kraus, R. Seger, and Z. Naor Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter Endocrinology 143 2002 1018 1025
15. G.R. Hart, H. Gowing, and J.M. Burrin Effects of a novel hypothalamic peptide, pituitary adenylate cyclase-activating polypeptide, on pituitary hormone release in rats J Endocrinol 134 1992 33 41
16. H. Hashimoto Physiological significance of pituitary adenylate cyclase-activating polypeptide (PACAP) in the nervous system Yakugaku Zasshi 122 2002 1109 1121
17. H. Hashimoto, K. Yamamoto, N. Hagigara, N. Ogawa, A. Nishino, and H. Aino cDNA cloning of a mouse pituitary adenylate cyclase-activating polypeptide receptor Biochim Biophys Acta 1281 1996 129 133
18. L. Jin, I. Tsumanuma, K.H. Ruebel, J.M. Bayliss, and R.V. Lloyd Analysis of homogeneous populations of anterior pituitary folliculostellate cells by laser capture microdissection and reverse transcription-polymerase chain reaction Endocrinology 142 2001 1703 1709
19. U.B. Kaiser, A. Jakubowiak, A. Steinberger, and W.W. Chin Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro Endocrinology 138 1997 1224 1231
20. U.B. Kaiser, E. Sabbagh, R.A. Katzenellenbogen, P.M. Conn, and W.W. Chin A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone Proc Natl Acad Sci USA 92 1995 12280 12284
21. H. Kanasaki, G.Y. Bedecarrats, K.Y. Kam, S. Xu, and U.B. Kaiser Gonadotropin-releasing hormone pulse frequency-dependent activation of extracellular signal-regulated kinase pathways in perifused LbetaT2 cells Endocrinology 146 2005 5503 5513
22. H. Kanasaki, S. Mutiara, A. Oride, I.N. Purwana, and K. Miyazaki Pulse frequency-dependent gonadotropin gene expression by adenylate cyclase-activating polypeptide 1 in perifused mouse pituitary gonadotroph LbetaT2 cells Biol Reprod 81 3 2009 465 472
23. K. Koves, O. Kantor, J.G. Scammell, and A. Arimura PACAP colocalizes with luteinizing and follicle-stimulating hormone immunoreactivities in the anterior lobe of the pituitary gland Peptides 19 1998 1069 1072
24. W. Kuohung, and U.B. Kaiser Gonadotropin-releasing hormone & gonadotropins J. Leslie, J.L.J. DeGroot, Endocrinology 2006 Elsevier Saunders Philadelphia 2649 2668
25. S. Lariviere, G. Garrel-Lazayres, V. Simon, N. Shintani, A. Baba, and R. Counis Gonadotropin-releasing hormone inhibits pituitary adenylyl cyclase-activating polypeptide coupling to 3′,5′-cyclic adenosine-5′-monophosphate pathway in LbetaT2 gonadotrope cells through novel protein kinase C isoforms and phosphorylation of pituitary adenylyl cyclase-activating polypeptide type I receptor Endocrinology 149 2008 6389 6398
26. S. Lariviere, G. Garrel, M.T. Robin, R. Counis, and J. Cohen-Tannoudji Differential mechanisms for PACAP and GnRH cAMP induction contribute to cross-talk between both hormones in the gonadotrope LbetaT2 cell line Ann N Y Acad Sci 1070 2006 376 379
27. S. Lariviere, G. Garrel, V. Simon, J.W. Soh, J.N. Laverriere, and R. Counis Gonadotropin-releasing hormone couples to 3′,5′-cyclic adenosine-5′-monophosphate pathway through novel protein kinase Cdelta and -epsilon in LbetaT2 gonadotrope cells Endocrinology 148 2007 1099 1107
28. F. Liu, D.A. Austin, P.L. Mellon, J.M. Olefsky, and N.J. Webster GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells Mol Endocrinol 16 2002 419 434
29. F. Liu, I. Usui, L.G. Evans, D.A. Austin, P.L. Mellon, and J.M. Olefsky Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells J Biol Chem 277 2002 32099 32108
30. A. Miyata, A. Arimura, R.R. Dahl, N. Minamino, A. Uehara, and L. Jiang Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells Biochem Biophys Res Commun 164 1989 567 574
31. A. Miyata, L. Jiang, R.D. Dahl, C. Kitada, K. Kubo, and M. Fujino Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38) Biochem Biophys Res Commun 170 1990 643 648
32. J.P. Moore Jr., L.L. Burger, A.C. Dalkin, and S.J. Winters Pituitary adenylate cyclase activating polypeptide messenger RNA in the paraventricular nucleus and anterior pituitary during the rat estrous cycle Biol Reprod 73 2005 491 499
33. J.P. Moore Jr., B.C. Villafuerte, C.A. Unick, and S.J. Winters Developmental changes in pituitary PACAP expression during the perinatal period: possible role in fetal gonadotroph regulation Endocrinology 150 10 2009 4802 4809
34. J.P. Moore Jr., L. Wilson, A.C. Dalkin, and S.J. Winters Differential expression of the pituitary gonadotropin subunit genes during male rat sexual maturation: reciprocal relationship between hypothalamic pituitary adenylate cyclase-activating polypeptide and follicle-stimulating hormone beta expression Biol Reprod 69 2003 234 241
35. S. Mutiara, H. Kanasaki, A. Oride, I.N. Purwana, S. Shimasaki, and H. Yamamoto Follistatin gene expression by gonadotropin-releasing hormone: a role for cyclic AMP and mitogen-activated protein kinase signaling pathways in clonal gonadotroph LbetaT2 cells Mol Cell Endocrinol 307 2009 125 132
36. K. Okazaki, Y. Itoh, K. Ogi, S. Ohkubo, and H. Onda Characterization of murine PACAP mRNA Peptides 16 1995 1295 1299
37. F. Pernasetti, V.V. Vasilyev, S.B. Rosenberg, J.S. Bailey, H.J. Huang, and W.L. Miller Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model Endocrinology 142 2001 2284 2295
38. A. Radleff-Schlimme, S. Leonhardt, W. Wuttke, and H. Jarry Evidence for PACAP to be an autocrine factor on gonadotrope cells Ann N Y Acad Sci 865 1998 486 491
39. S.R. Rawlings, and M. Hezareh Pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP/vasoactive intestinal polypeptide receptors: actions on the anterior pituitary gland Endocr Rev 17 1996 4 29
40. M.S. Roberson, A. Misra-Press, M.E. Laurance, P.J. Stork, and R.A. Maurer A role for mitogen-activated protein kinase in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone Mol Cell Biol 15 1995 3531 3539
41. M.S. Roberson, T. Zhang, H.L. Li, and J.M. Mulvaney Activation of the p38 mitogen-activated protein kinase pathway by gonadotropin-releasing hormone Endocrinology 140 1999 1310 1318
42. G.V. Segre, and S.R. Goldring Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagonlike peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family Trends Endocrinol Metab 4 1993 309 314
43. N.M. Sherwood, S.L. Krueckl, and J.E. McRory The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily Endocr Rev 21 2000 619 670
44. S.S. Stojilkovic, J. Reinhart, and K.J. Catt Gonadotropin-releasing hormone receptors: structure and signal transduction pathways Endocr Rev 15 1994 462 499
45. V.V. Vasilyev, F. Pernasetti, S.B. Rosenberg, M.J. Barsoum, D.A. Austin, and N.J. Webster Transcriptional activation of the ovine follicle-stimulating hormone-beta gene by gonadotropin-releasing hormone involves multiple signal transduction pathways Endocrinology 143 2002 1651 1659
46. D. Vaudry, A. Falluel-Morel, S. Bourgault, M. Basille, D. Burel, and O. Wurtz Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery Pharmacol Rev 61 2009 283 357
47. D. Vaudry, B.J. Gonzalez, M. Basille, L. Yon, A. Fournier, and H. Vaudry Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions Pharmacol Rev 52 2000 269 324
48. S. Vigh, A. Arimura, K. Koves, A. Somogyvari-Vigh, J. Sitton, and C.D. Fermin Immunohistochemical localization of the neuropeptide, pituitary adenylate cyclase activating polypeptide (PACAP), in human and primate hypothalamus Peptides 12 1991 313 318
49. L. Wildt, A. Hausler, G. Marshall, J.S. Hutchison, T.M. Plant, and P.E. Belchetz Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey Endocrinology 109 1981 376 385 (Pubitemid 11040187)
50. S.J. Winters, D. Ghooray, Y. Fujii, J.P. Moore Jr., J.R. Nevitt, and S.S. Kakar Transcriptional regulation of follistatin expression by GnRH in mouse gonadotroph cell lines: evidence for a role for cAMP signaling Mol Cell Endocrinol 271 2007 45 54
51. T. Yokoi, M. Ohmichi, K. Tasaka, A. Kimura, Y. Kanda, and J. Hayakawa Activation of the luteinizing hormone beta promoter by gonadotropin-releasing hormone requires c-Jun NH2-terminal protein kinase J Biol Chem 275 2000 21639 21647