Telomerase activity and serum levels of p53 protein as prognostic factors of survival in patients with advanced non-small cell lung cancer

Respiratory Medicine

Volumn 104, Issue 9, 2010, Pages 1356-1361

  Targowski, Tomasz ^a   Jahnz Rozyk, Karina ^a   Owczarek, Witold ^a   Raczka, Alicja ^a   Janda, Pawel ^a   Szkoda, Tomasz ^b   Płusa, Tadeusz ^a  

^a MILITARY INSTITUTE OF MEDICINE   (Poland)

^b NATIONAL INSTITUTE OF HYGIENE   (Poland)

Author keywords

Lung cancer; NSCLC; p53; Prognosis; Telomerase

Indexed keywords

PROTEIN P53; TELOMERASE;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG ASPIRATION; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; NEEDLE BIOPSY; POLYMERASE CHAIN REACTION; PRIMARY TUMOR; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; SURVIVAL TIME; TUMOR VOLUME;

AGED; BIOPSY, FINE-NEEDLE; CARCINOMA, NON-SMALL-CELL LUNG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROBABILITY; PROGNOSIS; SURVIVAL ANALYSIS; TELOMERASE; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77955656284     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2010.03.006     Document Type: Article

References (36)

1. C.F. Mountain Revisions in the international system for staging lung cancer Chest 111 1997 1710 1717
2. T. Hirashima, O. Yoshitaka, T. Nitta, S. Sasada, M. Kobayashi, and N. Masuda et al. Telomerase activity in endoscopically visible lung cancer Anticancer Res 21 5 2001 3685 3689
3. K. Hiyama, E. Hiyama, S. Ishioka, M. Yamakido, K. Inai, and F. Gazdar et al. Telomerase activity in small-cell and non-small-cell lung cancers J Natl Cancer Inst 87 1995 895 902
4. A. Marchetti, G. Bertacca, F. Buttitta, A. Chella, G. Quattrocolo, and C.A. Angeletti et al. Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer Clin Cancer Res 5 1999 2077 2081
5. T. Targowski, K. Jahnz-Rozyk, W. Owczarek, P. Janda, T. Szkoda, and T. Płusa Telomerase activity in transthoracic fine-needle biopsy aspirates from non-small cell lung cancer as prognostic factor of patients' survival Lung Cancer 61 2008 97 103
6. T. Targowski, and K. Jahnz-Różyk Diagnostic and prognostic value of telomerase activity in lung cancer Arch Med Sci 4 2008 4
7. D.N. Cooper An introduction to the molecular basis of cancer Cooper The molecular genetics of lung cancer 2005 Springer Heidelberg, Germany 1 18
8. D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
9. N.W. Kim, M.A. Piatyszek, K.R. Prowse, C.B. Harley, M.D. West, and P.L. Ho et al. Specific association of human telomerase activity with immortal cells and cancer Science 266 1994 2011 2015
10. Telo TAGGG Telomerase PCR ELISA Telo TAGGG Telomerase PCR Elisa PLUS Photometric enzyme immunoassay for quantitative determination of telomerase activity, utilizing the telomeric repeat amplification protocol (TRAP) Instruction Manual 1999 1999 Roche Diagnostics Manheim, Germany
11. p53 pan ELISA Photomeric one-step-enzyme-immunoassay for the quantification of p53 in cell homogenates, plasma or serum Instruction Manual 2004 1999 Roche Diagnostics Manheim, Germany
12. K.S. Albain, J.J. Crowley, M. LeBlanc, and R.B. Livingston Survival determinants in extensive-stage non-small-cell lung cancer: the Southwest Oncology Group experience J Clin Oncol 9 9 1991 1618 1626
13. E. Espinosa, J. Feliu, P. Zamora, M. Gonzalez Baron, J.J. Sanchez, and A. Ordon ez et al. Serum albumin and other prognostic factors related to response and survival in patients with advanced nonsmall cell lung cancer Lung Cancer 12 1/2 1995 67 76
14. M. Paesmans, J.P. Sculier, P. Libert, G. Bureau, G. Dabouis, and J. Thiriaux et al. Prognostic factors for survival in advanced non-small-cell lung cancer: univariate and multivariate analyses including recursive partitioning and amalgamation algorithms in 1052 patients. The European Lung Cancer Working Party J Clin Oncol 13 5 1995 1221 1230
15. L.M. Pedersen, and N. Milman Prognostic significance of thrombocytosis in patients with primary lung cancer Eur Respir J 9 9 1996 1826 1830
16. K. Roszkowski Nowotwory płuc Kus Rowinska-Zakrzewska, editor. Choroby układu oddechowego 2004 PZWL Warsaw 563 597
17. N. Takigawa, Y. Segawa, M. Okahara, Y. Maeda, I. Takata, and M. Kataoka et al. Prognostic factors for patients with advanced nonsmall cell lung cancer: univariate and multivariate analyses including recursive partitioning and amalgamation Lung Cancer 15 1 1996 67 77
18. W.D. Travis, E. Brambilla, and Müller-Hermelink Pathology and genetics of tumours of the lung, pleura, thymus and heart WHO classification of tumours 2004 IARC Press Lyon 1 25 [14]
19. E. Hiyama, T. Saeki, K. Hiyama, S. Takashima, J.W. Shay, and Y. Matsuura et al. Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples Cancer 90 4 2000 235 238
20. L.A. Langford, M.A. Piatyszek, R. Xu, S.C. Schold Jr., and J.W. Shay Telomerase activity in human brain tumors Lancet 346 1995 1267 1268
21. H. Tahara, T. Nakanishi, M. Kitamoto, R. Nakashio, J.W. Shay, and E. Tahara et al. Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinoma Cancer Res 55 1995 2734 2736
22. G. Xinarianos, F.M. Scott, T. Liloglou, W. Prime, L. Turnbull, and M. Walshaw et al. Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease Lung Cancer 28 2000 37 42
23. T. Targowski, K. Jahnz-Rozyk, T. Szkoda, S. From, N. Qandil, and T. Płusa Telomerase activity in transthoracic fine-needle biopsy aspirates as a marker of peripheral lung cancer Thorax 63 2008 342 344
24. Y. Fujita, T. Fujikane, S. Fujiuchi, Y. Nishigaki, Y. Yamazaki, and A. Nagase et al. The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with non-small cell lung carcinoma Cancer 98 5 2003 1008 1013
25. T.C. Wu, P. Lin, C.P. Hsu, Y.J. Huang, C.Y. Chen, and W.C. Chung et al. Loss of telomerase activity may be a potential favourable prognostic marker in lung carcinomas Lung Cancer 41 2 2003 163 169
26. K.Y. Chen, L.N. Lee, C.J. Yu, Y.C. Lee, S.H. Kuo, and P.C. Yang Elevation of telomerase activity positively correlates to poor prognosis of patients with non-small cell lung cancer Cancer Lett 21 2005 1 9
27. C.Q. Zhu, J.C. Cutz, N. Liu, D. Lau, F.A. Shepherd, and J.A. Squire et al. Amplification of telomerase gene is a poor prognostic marker in non-small-cell lung cancer Br J Cancer 94 10 2006 1452 1459
28. I. Chiba, T. Takahashi, M.M. Naum, D. D'Amico, D.T. Curiel, T. Mitsudomi, D.L. Buchhangen, and D. Carbone et al. Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group Oncogene 5 10 1990 1603 1610
29. M. Bergqvist, D. BrattstrÖm, A. Larsson, P. Hesselius, O. Brodin, and G. Wagenius The role of circulating anti-p53 antibodies in patients with advanced non-small cell lung cancer and their correlation to clinical parameters and survival BMC Cancer 4 2004 66 71
30. J. Niklinski, W. Niklinska, J. Laudanski, E. Chyczewska, and I. Chyczewski Prognostic molecular markers in non-small cell lung cancer Lung Cancer 34 Suppl. 2 2001 S53 S58
31. J. Laudanski, T. Burzykowski, W. Niklinska, K. Chyczewski, M. Furman, and J. Niklinski Prognostic value of serum p53 antibodies in patients with resected non-small cell lung cancer Lung Cancer 22 3 1998 191 200
32. T. Kosaka, Y. Yatabe, R. Onozato, H. Kuwano, and T. Mitsudomi Prognostic implication of EGFR, KRAS, and TP53 gene mutations in a large cohort of Japanese patients with surgically treated lung adenocarcinoma J Thorac Oncol 4 1 2009 22 29
33. M. Bergqvist, D. Brattström, K. Lamberg, P. Hesselius, J. Wernlund, A. Larsson, and G. Wagenius The presence of anti-p53 antibodies in sera prior to thoracic surgery in non small cell lung cancer patients: its implications on tumor volume, nodal involvement, and survival Neoplasia 5 4 2003 283 287
34. F.H. Sarkar, Y. Li, and V. Vallyathan Molecular analysis of p53 and K-ras in lung carcinomas of coal miners Int J Mol Med 8 4 2001 453 459
35. S. Cho, S.W. Sung, S. Jheon, and J.H. Chung Risk of recurrence in surgically resected stage I adenocarcinoma of the lung: histopathologic and immunohistochemical analysis Lung 186 6 2008 411 419
36. M. Strazisar, T. Rott, and D. Glavac K-RAS and P53 mutations in association with COX-2 and hTERT expression and clinico-pathological status of NSCLC patients Dis Markers 25 2 2008 97 106