Association between depression and anxiety in high-functioning children with autism spectrum disorders and maternal mood symptoms

Autism Research

Volumn 3, Issue 3, 2010, Pages 120-127

  Mazefsky, Carla A ^a   Conner, Caitlin M ^a   Oswald, Donald P ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anxiety; Asperger's disorder; Autism; Depression; Familial aggregation; Maternal symptoms; Mood disorders; Psychiatric comorbidity

Indexed keywords

ADOLESCENT; ANXIETY DISORDER; ARTICLE; AUTISM; CHILD; CLINICAL ARTICLE; DEPRESSION; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HOSTILITY; HUMAN; MALE; MOOD DISORDER; PHOBIA; PRIORITY JOURNAL; SCHOOL CHILD; SEMI STRUCTURED INTERVIEW; STRUCTURED QUESTIONNAIRE; ANXIETY DISORDERS; CROSS-SECTIONAL STUDY; DEPRESSIVE DISORDER; GENETIC PREDISPOSITION; GENETICS; INFANT; INTELLIGENCE; MOOD DISORDERS; MOTHER; PERSONALITY TEST; PSYCHOLOGY; PSYCHOMETRY; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

ADOLESCENT; ANXIETY DISORDERS; CHILD; CHILD OF IMPAIRED PARENTS; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; INTELLIGENCE; MALE; MOOD DISORDERS; MOTHERS; PERSONALITY INVENTORY; PSYCHOMETRICS; RISK FACTORS;

EID: 77955645552     PISSN: 19393792     EISSN: 19393806     Source Type: Journal    
DOI: 10.1002/aur.133     Document Type: Article

References (34)

1. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, (Revised 4e).Washington, DC: American Psychiatric Association.
2. Bolton, P.F., Pickles, A., Murphy, M., & Rutter, M. (1998). Autism, affective and other psychiatric disorders: Patterns of familial aggregation. Psychological Medicine, 28, 385-395. (Pubitemid 28197553)
3. Carmody, T.P., Crossen, J.R., &Wiens, A.N. (1989). Hostility as a health risk factor: Relationships with neuroticism, type A behavior, attentional focus, and interpersonal style. Journal of Clinical Psychology, 45, 754-762.
4. Carpenter, K.M., & Hittner, J.B. (1995). Dimensional characteristics of the SCL-90-R: Evaluation of gender differences in dually diagnosed inpatients. Journal of Clinical Psychology, 51, 383-390.
5. DeLong, R. (2004). Autism and familial major mood disorder: Are they related? The Journal of Neuropsychiatry and Clinical Neurosciences, 16, 199-213.
6. Derogatis, L.R. (1994). Symptom Checklist-90-R: Administration, scoring, and procedures manual,3e. Minneapolis, MN; NCS Pearson, Inc.
7. Ghaziuddin, M. (2005). A family history study of Asperger syndrome. Journal of Autism and Developmental Disorders, 35, 177-182.
8. Ghaziuddin, M., & Greden, J. (1998). Depression in children with autism/pervasive developmental disorders: A case-control family history study. Journal of Autism and Developmental Disorders, 28, 111-115.
9. Ghaziuddin, M., Ghaziuddin, N., & Greden, J. (2002). Depression in persons with autism: Implications for research and clinical care. Journal of Autism and Developmental Disorders, 32, 299-306.
10. Kendler, K.S. (2001). Twin studies of psychiatric illness: An update. Archives of General Psychiatry, 58, 1005-1014.
11. Kessler, R.C., Berglund, P., Demler, O., Jin, R., Merikangas, K.R., & Walters, E.E. (2005). Lifetime prevaalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication. Archive of General Psychiatry, 62, 593-602. (Pubitemid 40973434)
12. Lainhart, J.E. (1999). Psychiatric problems in individuals with autism, their parents and siblings. International Review of Psychiatry, 11, 278-298.
13. Leyfer, O., Folstein, S., Bacalman, S., Davis, N., Dinh, E., et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849-861.
14. Lord, C., Rutter, M., & LeCouteur, A.L. (1994). Autism Diagnostic Interview-Revised: A revised version of the diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659-685. (Pubitemid 24309810)
15. Lord, C., Risi, S., Lambrecht, L., Cook, E.H.J., Leventhal, B.L., et al. (2000). The Autism Diagnostic Observation Schedule- Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205-223.
16. Mazefsky, C.A., Folstein, S.E., & Lainhart, J.E. (2008a). Brief Report: Overrepresentation of mood and anxiety disorders in adults with autism and their first degree relatives: What does it mean? Autism Research, 1, 193-197.
17. Mazefsky, C.A., Williams, D.L., & Minshew, N.J. (2008b). Variability in adaptive behavior in autism: Evidence for the importance of family history. Journal of Abnormal Child Psychology, 36, 591-599.
18. Mazefsky, C.A., Kao, J., & Oswald, D.P. (in press 2010). Preliminary evidence suggesting caution in the use of phychiatric self-report measures with adolescents with high-functioning autism spectrum disorders. Research in Autism Spectrum Disorders, doi:10.1016/j.rasd.2010.03.006.
19. Middledorp, C.M., Cath, D.C., Van Dyck, R., & Boomsma, D.I. (2005). The Co-morbidity of anxiety and depression in the perspective of genetic epidemiology. A review of twin and family studies. Psychological Medicine, 35, 611-624.
20. Murphy, M., Bolton, P.F., Pickles, A., Fombonne, E., Piven, J., & Rutter, M. (2000). Personality traits of the relatives of autistic probands. Psychological Medicine, 30, 1411-1424.
21. Nes, R.B., Roysamb, E., Reichborn-Kjennerud, T., Harris, J.R., & Tambs, K. (2007). Symptoms of anxiety and depression in young adults: Genetic and environmental influences on stability and change. Twin Research and Human Genetics, 10, 450-461. (Pubitemid 46984002)
22. Piven, J., & Palmer, P. (1999). Psychiatric disorder and the Broad Autism Phenotype: Evidence from a family study of multiple-incidence autism families. American Journal of Psychiatry, 156, 557-563. (Pubitemid 29162976)
23. Piven, J., Chase, G.A., Landa, R., Wzorek, M., Gayle, J., et al. (1991). Psychiatric disorders in the parents of autistic individuals. Journal of the American Academy of Child and Adolescent Psychiatry, 30, 471-478.
24. Rauter, U.K., Leonard, C.E., & Swett, C.P. (1996). SCL-90-R factor structure in an acute, involuntary, adult psychiatric inpatient sample. Journal of Clinical Psychology, 52, 625-629.
25. Schmitz, N., Hartkamp, N., Kiuse, J., Franke, G.H., Reister, G., & Tress, W. (2000). The Symptom Check-List-90-R (SCL-90-R): A German validation study. Quality of Life Research, 9, 185-193.
26. Singer, G.H.S. (2006). Meta-Analysis of comparative studies of depression in mothers of children with and without developmental disabilities. American Journal on Mental Retardation, 111, 155-169.
27. Spitzer, R.L., & Endicott, J. (1978). Schedule for affective disorders and schizophrenia, 3e. Washington, DC: US Government Printing Office. NIMH Clinical Research Branch, Collaborative Program on the Psychology of Depression.
28. Sterling, L., Dawson, G., Estes, A., & Greenson, J. (2008). Characteristics associated with presence of depressive symptoms in adults with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 38, 1011-1018.
29. Stewart, M.E., Barnard, L., Pearson, J., Hasan, R., & O'Brien, G. (2006). Presentation of depression in autism and Asperger syndrome: A review. Autism, 10, 103-116.
30. Sullivan, P.F., Neale, M.C., & Kendler, K.S. (2000). Genetic epidemiology of major depression: Review and meta-analysis. American Journal of Psychiatry, 157, 1552-1562.
31. Tambs, K. (1991). Transmission of symptoms of anxiety and depression in nuclear families. Journal of Affective Disorders, 21, 117-126.
32. Tsankanikos, E., Costello, H., Holt, G., Bouras, N., Sturmey, P., & Newton, T. (2006). Psychopathology in adults with autism and intellectual disability. Journal of Autism and Developmental Disorders, 36, 1123-1129. (Pubitemid 46020364)
33. Weschler, D. (1999). Wechsler Abbreviated Scale of Intelligence. San Antonio, TX; The Psychological Corporation.
34. White, S.W., Oswald, D., Ollendick, T., & Scahill, L. (2009). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29, 216-229.