Seizures as a Cause of Altered Mental Status

Emergency Medicine Clinics of North America

Volumn 28, Issue 3, 2010, Pages 517-534

  Slattery, David E ^a   Pollack, Charles V ^b  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^b PENNSYLVANIA HOSPITAL   (United States)

Author keywords

Altered mental status; Seizure; Status epilepticus

Indexed keywords

ACTIVATED CARBON; ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CENTRAL STIMULANT AGENT; CYTOTOXIN; DEXTROPROPOXYPHENE; DIAZEPAM; FOSPHENYTOIN SODIUM; ISOFLURANE; ISONIAZID; LORAZEPAM; MIDAZOLAM; MUSCARINIC RECEPTOR; NICOTINIC RECEPTOR; OPIATE; PENICILLIN G; PENTOBARBITAL; PETHIDINE; PHENOBARBITAL; PHENYTOIN; PROPOFOL; PYRIDOXINE; TERRELL; THIOPENTAL; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROATE SEMISODIUM;

AGITATION; ANTICONVULSANT THERAPY; CARDIOTOXICITY; CENTRAL NERVOUS SYSTEM INFECTION; CLINICAL FEATURE; COMA; DIAPHORESIS; DIFFERENTIAL DIAGNOSIS; DISEASE ACTIVITY; DISEASE CLASSIFICATION; DISEASE CONTROL; DISEASE SEVERITY; DOSE RESPONSE; DRUG CONTRAINDICATION; DRUG DOSE TITRATION; DRUG MEGADOSE; DRUG OVERDOSE; DRUG TOXICITY; ECLAMPSIA; EMERGENCY WARD; EPILEPTIC STATE; HEART FAILURE; HUMAN; HYPERKALEMIA; HYPERTENSION; HYPERTHERMIA; HYPOGLYCEMIA; HYPOXIA; INTRACTABLE EPILEPSY; LOADING DRUG DOSE; LOCAL ANESTHESIA; MAINTENANCE DRUG DOSE; MENTAL DISEASE; METABOLIC ACIDOSIS; METABOLIC DISORDER; MYDRIASIS; NEUROTOXICITY; NONHUMAN; PATIENT ASSESSMENT; PRIORITY JOURNAL; PSEUDOEPILEPTIC SEIZURE; PSYCHOTHERAPY; QRS COMPLEX; REVIEW; RHABDOMYOLYSIS; SEIZURE; SIDE EFFECT; SYSTEMIC DISEASE; TACHYCARDIA; WITHDRAWAL SEIZURE;

EID: 77955643933     PISSN: 07338627     EISSN: 07338627     Source Type: Journal    
DOI: 10.1016/j.emc.2010.03.011     Document Type: Review

References (62)

1. Engel J.J., Starkman S. Overview of seizures. Emerg Med Clin North Am 1994, 12(4):895-923.
2. Huff J., Morris D., Kothari R., et al. Emergency department management of patients with seizures: a multicenter study. Acad Emerg Med 2001, 8(6):622-628.
3. Duviver E.H., Pollack C.V. Seizures. Rosen's emergency medicine: concepts and clinical practice 2010, 1346-1355. Mosby Elsevier, Philadelphia. 7th edition. J.A. Marx (Ed.).
4. Goldstein J.N., Greer D.M. Rapid focused neurological assessment in the emergency department and ICU. Emerg Med Clin North Am 2009, 27(1):1-16. vii.
5. Chen J., Wasterlain C. Status epilepticus: pathophysiology and management in adults. Lancet Neurol 2006, 5(3):246-256.
6. Lowenstein D., Bleck T., Macdonald R. It's time to revise the definition of status epilepticus. Epilepsia 1999, 40(1):120-122.
7. Millikan D., Rice B., Silbergleit R. Emergency treatment of status epilepticus: current thinking. Emerg Med Clin North Am 2009, 27(1):101-113. ix.
8. Catlett C. Seizures and status epilepticus in adults. Emergency medicine: a comprehensive study guide 2004, 1409-1417. McGraw-Hill, New York (NY). 6th edition. J.E. Tintinalli (Ed.).
9. Goodkin H., Kapur J. Responsiveness of status epilepticus to treatment with diazepan decreases rapidly as seizure duration increases. Epilepsy Curr 2003, 3(1):11-12.
10. 2+ sensitivity of hippocampal dentate granule cell GABAA receptors. J Neurosci 1997, 17(19):7532-7540.
11. Knake S., Hamer H., Rosenow F. Status epilepticus: a critical review. Epilepsy Behav 2009, 15(1):10-14.
12. Bearden S., Eisenschenk S., Uthman B. Diagnosis of nonconvulsive status epilepticus (NCSE) in adults with altered mental status: clinico-electroencephalographic considerations. Am J Electroneurodiagnostic Technol 2008, 48(1):11-37.
13. Drislane F.W., Lopez M.R., Blum A.S., et al. Detection and treatment of refractory status epilepticus in the intensive care unit. J Clin Neurophysiol 2008, 25(4):181-186.
14. Drislane F.W. Evidence against permanent neurologic damage from nonconvulsive status epilepticus. J Clin Neurophysiol 1999, 16(4):323-331. [discussion: 353].
15. Husain A.M., Horn G.J., Jacobson M.P. Non-convulsive status epilepticus: usefulness of clinical features in selecting patients for urgent EEG. J Neurol Neurosurg Psychiatry 2003, 74(2):189-191.
16. Beyenburg S., Elger C.E., Reuber M. Acute confusion or altered mental state: consider nonconvulsive status epilepticus. Gerontology 2007, 53(6):388-396.
17. Towne A., Waterhouse E., Boggs J., et al. Prevalence of nonconvulsive status epilepticus in comatose patients. Neurology 2000, 54(2):340-345.
18. Praline J., Grujic J., Corcia P., et al. Emergent EEG in clinical practice. Clin Neurophysiol 2007, 118(10):2149-2155.
19. Bautista R.E., Godwin S., Caro D. Incorporating abbreviated EEGs in the initial workup of patients who present to the emergency room with mental status changes of unknown etiology. J Clin Neurophysiol 2007, 24(1):16-21.
20. Hauf M., Slotboom J., Nirkko A., et al. Cortical regional hyperperfusion in nonconvulsive status epilepticus measured by dynamic brain perfusion CT. AJNR Am J Neuroradiol 2009, 30(4):693-698.
21. Bazakis A.M., Kunzler C. Altered mental status due to metabolic or endocrine disorders. Emerg Med Clin North Am 2005, 23(3):901-908. x-xi.
22. Graffeo C. Hyperosmolar hyperglycemic state. Emergency medicine: a comprehensive study guide 2004, 1307-1311. McGraw-Hill, New York (NY). 6th edition. J. Tintinalli (Ed.).
23. Kacprowicz R., Lloyd J. Electrolyte complications of malignancy. Emerg Med Clin North Am 2009, 27(2):257-269.
24. Londner M. Fluid and electrolyte problems. Emergency medicine: a comprehensive study guide 2004, 167-179. McGraw-Hill, New York (NY). 6th edition. J. Tintinalli (Ed.).
25. Wills B., Erickson T. Chemically induced seizures. Clin Lab Med 2006, 26:185-209.
26. Kunisaki T., Augenstein W. Drug- and toxin-induced seizures. Emerg Med Clin North Am 1994, 12(4):1027-1056.
27. Morrow E., Roffman J., Wolf D., et al. Psychiatric neuroscience: incorporating pathophysiology into clinical case formulation. Stern: Massachusetts General Hospital comprehensive clinical psychiatry 2008, 562. Mosby, Philadelphia (PA). 1st edition. T.A. Stern, J.F. Rosenbaum, M. Fava (Eds.).
28. Hughes J. Alcohol withdrawal seizures. Epilepsy Behav 2009, 15(2):92-97.
29. Tetrault J., O'Connor P. Substance abuse and withdrawal in the critical care setting. Crit Care Clin 2008, 24(4):767-788. viii.
30. Richardson W.H., Slone C.M., Michels J.E. Herbal drugs of abuse: an emerging problem. Emerg Med Clin North Am 2007, 25(2):435-457. [abstract ix].
31. Perrone J. Cocaine, amphetamines, caffeine, and nicotine. Emergency medicine: a comprehensive study guide 2004, 1075-1079. McGraw-Hill, New York (NY). 6th edition. J. Tintinalli (Ed.).
32. Jalbert E. Seizures after penicillin administration. Am J Dis Child 1985, 139(11):1075.
33. Ew B. Antituberculosis medications. Goldfrank's toxicologic emergencies 2006, 861-871. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
34. Brent J., Vo N., Kulig K., et al. Reversal of prolonged isoniazid-induced coma by pyridoxine. Arch Intern Med 1990, 150(8):1751-1753.
35. Stork C., Redd J., Fine K., et al. Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate-a case report. J Toxicol Clin Toxicol 1995, 33(2):179-183.
36. Nelson L. Opioids. Goldfrank's toxicologic emergencies 2006, 591-613. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
37. Henry K., Harris C. Deadly ingestions. Pediatr Clin North Am 2006, 53(2):293-315.
38. Liebelt E. Cyclic antidepressants. Goldfrank's toxicologic emergencies 2006, 1083-1097. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
39. Michael J., Sztajnkrycer M. Deadly pediatric poisons: nine common agents that kill at low doses. Emerg Med Clin North Am 2004, 22(4):1019-1050.
40. Stork C. Serotonin reuptake inhibitors and atypical antidepressants. Goldfrank's toxicologic emergencies 2006, 1070-1082. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
41. Greller H.A. Lithium. Goldfrank's toxicologic emergencies 2006, 1052-1061. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
42. Mokhlesi B., Leikin J., Murray P., et al. Adult toxicology in critical care: part II: specific poisonings. Chest 2003, 123(3):897-922.
43. Dorf E., Kuntz A.F., Kelsey J., et al. Lidocaine-induced altered mental status and seizure after hematoma block. J Emerg Med 2006, 31(3):251-253.
44. Schwartz D.R., Kaufman B. Local anesthetics. Goldfrank's toxicologic emergencies 2006, 1004-1015. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
45. Harden C., Huff J., Schwartz T., et al. Reassessment: neuroimaging in the emergency patient presenting with seizure (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2007, 69(18):1772-1780.
46. Kao L., Nañagas K. Carbon monoxide poisoning. Med Clin North Am 2005, 89(6):1161-1194.
47. Perrone J. Iron. Goldfrank's toxicologic emergencies 2006, 629-637. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
48. Holstege C., Dobmeier S., Bechtel L. Critical care toxicology. Emerg Med Clin North Am 2008, 26(3):715-739. viii-ix.
49. Tomassoni A.J. Antihistamines and decongestants. Goldfrank's toxicologic emergencies 2006, 785-793. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
50. Burns M., Linden C., Graudins A., et al. A comparison of physostigmine and benzodiazepines for the treatment of anticholinergic poisoning. Ann Emerg Med 2000, 35(4):374-381.
51. Robe W.C., Meggs W.J. Insecticides, herbicides, rodenticides. Goldfrank's toxicologic emergencies 2006, 1134-1143. McGraw-Hill, New York (NY). 8th edition. N.E. Flomenbaum, L.R. Goldfrank, R.S. Hoffman (Eds.).
52. Ben-Ami T., Sinai L., Granot E. Afebrile seizures and rotavirus gastroenteritis: an infrequently recognized association. Clin Pediatr (Phila) 2007, 46(2):178-180.
53. Bennish M. Potentially lethal complications of shigellosis. Rev Infect Dis 1991, 13(Suppl 4):S319-S324.
54. Salam M, Bennish M Antimicrobial therapy for shigellosis. Rev Infect Dis 1991, 13(Suppl 4):S332-S341.
55. Somand D., Meurer W. Central nervous system infections. Emerg Med Clin North Am 2009, 27(1):89-100. ix.
56. Damek D.M. Cerebral edema, altered mental status, seizures, acute stroke, leptomeningeal metastases, and paraneoplastic syndrome. Emerg Med Clin North Am 2009, 27(2):209-229.
57. Antunes N.L., De Angelis L.M. Neurologic consultations in children with systemic cancer. Pediatr Neurol 1999, 20(2):121-124.
58. Leroux G., Sellam J., Costedoat-Chalumeau N., et al. Posterior reversible encephalopathy syndrome during systemic lupus erythematosus: four new cases and review of the literature. Lupus 2008, 17(2):139-147.
59. Servillo G., Bifulco F., De Robertis E., et al. Posterior reversible encephalopathy syndrome in intensive care medicine. Intensive Care Med 2007, 33(2):230-236.
60. Zhang J., Meikle S., Trumble A. Severe maternal morbidity associated with hypertensive disorders in pregnancy in the United States. Hypertens Pregnancy 2003, 22(2):203-212.
61. Duley L., Henderson-Smart D. Magnesium sulphate versus diazepam for eclampsia. Cochrane Database Syst Rev 2003, 4. CD000127.
62. Sibai B. Diagnosis, prevention, and management of eclampsia. Obstet Gynecol 2005, 105(2):402-410.