Marmarou weight drop injury model

Animal Models of Acute Neurological Injuries

Volumn , Issue , 2009, Pages 393-407

  Marmarou, Christina R ^a   Prieto, Ruth ^a   Taya, Keisuke ^a   Young, Harold F ^a   Marmarou, Anthony ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cellular edema; Diffuse traumatic brain injury (DTBI); Intracranial pressure (ICP); Neurobehavioral deficits; Neuronal damage; Rat; Secondary injury; Traumatic axonal damage

Indexed keywords

EID: 77955642314     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-60327-185-1_34     Document Type: Chapter

References (14)

1. Marmarou A, Foda MA, Van Den Brink W, Campbell J, Kita H, Demetriadou K. A new model of diffuse brain injury in rats Par I: Pathophysiology and biomechan-ics. J Neurosurg 1994; 80: 291-300
2. Foda MA, Marmarou A. A new model of diffuse brain injury in rats Part II: Morphological characterization. J Neurosurg 1994; 80: 301-13.
3. Adams JH, Doyley D, Ford I, Gennarelli TA, Graham DI and McLellan DR: Diffuse axonal injury in head injury: definition, diagnosis and grading. Histopathology 1989; 15: 49-59
4. Marshall LF, Gautille T, Klauber MR, Eisenberg HM, Jane J, Luessen TG, Marmarou A, Foulkes MA. The outcome of sever closed head injury. J Neurosurg 1991; 71: S28-S26.
5. Yamamoto M, Marmarou CR, Stiefel MF, Beaumont A, Marmarou A. Neuroprotective effect of hypothermia on neuronal injury in diffuse traumatic brain injury coupled with hypoxia and hypotension. J Neurotrauma 1999;16: 487-500.
6. Ito J, Marmarou A, Barzo P, Fatouros P, Corwin F. Characterization of edema by diffusion-weighted imaging in experimental traumatic brain injury. J Neurosurgery 1999; 84: 97-103
7. Marmarou CR, Walker SA, Davis CL, Povlishock JT. Quantitative analysis of the relationship between intra-axonal neurofilament compaction and impaired axonal transport following diffuse traumatic brain injury. J Neurotrauma 2005; 22: 1066-80.
8. Barzo P, Marmarou A, Fatouros P, Hayasaki K and Corwin F. Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imaging. J Neurosurg 1997; 87: 900-907
9. Beaumont A, Marmarou A, Hayasaki K, Barzo P, Fatouros P, Corwin F, Marmarou C, Dunbar J. The permissive nature of blood brain barrier (BBB) opening in edema formation following traumatic brain injury. Acta Neurochir Suppl 2000;76: 125-9.
10. Beaumont A, Marmarou A, Czigner A, Yamamoto M, Demetriadou K, Shirotani T, Marmarou C, Dunbar J. The impact-acceleration model of head injury: Injury severity predicts motor and cognitive performance after trauma. Neurol Res 1999; 21: 742-54
11. Beaumont A, Marmarou C, Marmarou A. The effects of human corticotrophin releasing factor on motor and cognitive deficits after impact acceleration injury. Neurol Res 2000; 22: 665-73.
12. Marmarou CR, Povlishock JT. Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury. Exp Neurol 2006; 197: 353-62.
13. Signoretti S, Marmarou A, Tavazzi B, Lazzarino G, Beaumont A, Vagnozzi R. N-Acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury. J Neurotrauma 2001; 18: 977-991
14. 1H NMR Spectroscopy. J Neurotrauma 2007; 24: 944-959