SCOPUS 정보 검색 플랫폼

ChemBioChem

Volumn 11, Issue 12, 2010, Pages 1645-1648

RAF kinase inhibitors in cancer treatment: Like a bull in a China shop?

(3) Robubi, Armin a Waldmann, Herbert b,c Rauh, Daniel a

a CHEMICAL GENOMICS CENTRE OF THE MAX PLANCK SOCIETY (Germany)

b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY (Germany)

c TU DORTMUND UNIVERSITY (Germany)

Author keywords

Antitumor agents; Chemical biology; Drug development; Signaling

Indexed keywords

2 [4 (1 HYDROXYIMINO 5 INDANYL) 3 (4 PYRIDINYL) 1H PYRAZOL 1 YL]ETHANOL; 2 [4 (2 DIMETHYLAMINOETHOXY)PHENYL] 4 (1 HYDROXYIMINO 5 INDANYL) 5 (4 PYRIDINYL) 1H IMIDAZOLE; 3 (3,5 DIBROMO 4 HYDROXYBENZYLIDENE) 1,3 DIHYDRO 5 IODO 2 INDOLONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AZ 628; B RAF KINASE; B RAF KINASE INHIBITOR; JAB 13; JAB 34; L 779450; MITOGEN ACTIVATED PROTEIN KINASE; N [5 (3 DIMETHYLAMINOBENZAMIDO) 2 METHYLPHENYL] 4 HYDROXYBENZAMIDE; PLX 4032; PLX 4720; RAS PROTEIN; SORAFENIB; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE MUTATION; GENETIC ASSOCIATION; HUMAN; INTRACELLULAR SIGNALING; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SHORT SURVEY; SOLID TUMOR; TUMOR GROWTH;

CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF;

EID: 77955637293 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201000348 Document Type: Short Survey

Times cited : (1)

References (23)

1
- 77950215269
- M. Rabiller, M. Getlik, S. Klüter, A. Richters, S. Tückmantel, J. R. Simard, D. Rauh, Arch. Pharm. 2010, 343, 193-206.
- (2010) Arch. Pharm. , vol.343 , pp. 193-206
- Rabiller, M.¹ Getlik, M.² Klüter, S.³ Richters, A.⁴ Tückmantel, S.⁵ Simard, J.R.⁶ Rauh, D.⁷

2
- 0036527429
- P. Cohen, Nat. Rev. Drug Discovery 2002, 1, 309-315.
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 309-315
- Cohen, P.¹

3
- 0033590636
- R. Hoshino, Y. Chatani, T. Yamori, T. Tsuruo, H. Oka, O. Yoshida, Y. Shimada, S. Ari-i, H. Wada, J. Fujimoto, M. Kohno, Oncogene 1999, 18, 813-822.
- (1999) Oncogene , vol.18 , pp. 813-822
- Hoshino, R.¹ Chatani, Y.² Yamori, T.³ Tsuruo, T.⁴ Oka, H.⁵ Yoshida, O.⁶ Shimada, Y.⁷ Ari-i, S.⁸ Wada, H.⁹ Fujimoto, J.¹⁰ Kohno, M.¹¹

4
- 18444374405
- H. Davies, G. R. Bignell, C. Cox, P. Stephens, S. Edkins, S. Clegg, J. Teague, H. Woffendin, M. J. Garnett, W. Bottomley, N. Davis, E. Dicks, R. Ewing, Y. Floyd, K. Gray, S. Hall, R. Hawes, J. Hughes, V. Kosmidou, A. Menzies, C. Mould, A. Parker, C. Stevens, S. Watt, S. Hooper, R. Wilson, H. Jayatilake, B. A. Gusterson, C. Cooper, J. Shipley, D. Hargrave, K. Pritchard-Jones, N. Maitland, G. Chenevix-Trench, G. J. Riggins, D. D. Bigner, G. Palmieri, A. Cossu, A. Flanagan, A. Nicholson, J. W. C. Ho, S. Y. Leung, S. T. Yuen, B. L. Weber, H. F. Seigler, T. L. Darrow, H. Paterson, R. Marais, C. J. Marshall, R. Wooster, M. R. Stratton, P. A. Futreal, Nature 2002, 417, 949-954.
- (2002) Nature , vol.417 , pp. 949-954
- Davies, H.¹ Bignell, G.R.² Cox, C.³ Stephens, P.⁴ Edkins, S.⁵ Clegg, S.⁶ Teague, J.⁷ Woffendin, H.⁸ Garnett, M.J.⁹ Bottomley, W.¹⁰ Davis, N.¹¹ Dicks, E.¹² Ewing, R.¹³ Floyd, Y.¹⁴ Gray, K.¹⁵ Hall, S.¹⁶ Hawes, R.¹⁷ Hughes, J.¹⁸ Kosmidou, V.¹⁹ Menzies, A.²⁰ more..

5
- 12144289677
- P. T. C. Wan, M. J. Garnett, S. M. Roe, S. Lee, D. Niculescu-Duvaz, V. M. Good, C. M. Jones, C. J. Marshall, C. J. Springer, D. Barford, R. Marais, C. G. Project, Cell 2004, 116, 855-867.
- (2004) Cell , vol.116 , pp. 855-867
- Wan, P.T.C.¹ Garnett, M.J.² Roe, S.M.³ Lee, S.⁴ Niculescu-Duvaz, D.⁵ Good, V.M.⁶ Jones, C.M.⁷ Marshall, C.J.⁸ Springer, C.J.⁹ Barford, D.¹⁰ Marais, R.¹¹ Project, C.G.¹²

6
- 0033179479
- C. A. Hall-Jackson, P. A. Eyers, P. Cohen, M. Goedert, F. T. Boyle, N. Hewitt, H. Plant, P. Hedge, Chem. Biol. 1999, 6, 559-568.
- (1999) Chem. Biol. , vol.6 , pp. 559-568
- Hall-Jackson, C.A.¹ Eyers, P.A.² Cohen, P.³ Goedert, M.⁴ Boyle, F.T.⁵ Hewitt, N.⁶ Plant, H.⁷ Hedge, P.⁸

7
- 0005318501
- C. A. Hall-Jackson, M. Goedert, P. Hedge, P. Cohen, Oncogene 1999, 18, 2047-2054.
- (1999) Oncogene , vol.18 , pp. 2047-2054
- Hall-Jackson, C.A.¹ Goedert, M.² Hedge, P.³ Cohen, P.⁴

8
- 77949685981
- G. Hatzivassiliou, K. Song, I. Yen, B. J. Brandhuber, D. J. Anderson, R. Alvarado, M. J. C. Ludlam, D. Stokoe, S. L. Gloor, G. Vigers, T. Morales, I. Aliagas, B. Liu, S. Sideris, K. P. Hoeflich, B. S. Jaiswal, S. Seshagiri, H. Koeppen, M. Belvin, L. S. Friedman, S. Malek, Nature 2010, 464, 431-435.
- (2010) Nature , vol.464 , pp. 431-435
- Hatzivassiliou, G.¹ Song, K.² Yen, I.³ Brandhuber, B.J.⁴ Anderson, D.J.⁵ Alvarado, R.⁶ Ludlam, M.J.C.⁷ Stokoe, D.⁸ Gloor, S.L.⁹ Vigers, G.¹⁰ Morales, T.¹¹ Aliagas, I.¹² Liu, B.¹³ Sideris, S.¹⁴ Hoeflich, K.P.¹⁵ Jaiswal, B.S.¹⁶ Seshagiri, S.¹⁷ Koeppen, H.¹⁸ Belvin, M.¹⁹ Friedman, L.S.²⁰ Malek, S.²¹ more..

9
- 77949732073
- P. I. Poulikakos, C. Zhang, G. Bollag, K. M. Shokat, N. Rosen, Nature 2010, 464, 427-430.
- (2010) Nature , vol.464 , pp. 427-430
- Poulikakos, P.I.¹ Zhang, C.² Bollag, G.³ Shokat, K.M.⁴ Rosen, N.⁵

10
- 74849109743
- S. J. Heidorn, C. Milagre, S. Whittaker, A. Nourry, I. Niculescu-Duvas, N. Dhomen, J. Hussain, J. S. Reis-Filho, C. J. Springer, C. Pritchard, R. Marais, Cell 2010, 140, 209-221.
- (2010) Cell , vol.140 , pp. 209-221
- Heidorn, S.J.¹ Milagre, C.² Whittaker, S.³ Nourry, A.⁴ Niculescu-Duvas, I.⁵ Dhomen, N.⁶ Hussain, J.⁷ Reis-Filho, J.S.⁸ Springer, C.J.⁹ Pritchard, C.¹⁰ Marais, R.¹¹

11
- 77949354563
- R. Halaban, W. Zhang, A. Bacchiocchi, E. Cheng, F. Parisi, S. Ariyan, M. Krauthammer, J. P. McCusker, Y. Kluger, M. Sznol, Pigment Cell Melanoma Res. 2010, 2, 190-200.
- (2010) Pigment Cell Melanoma Res. , vol.2 , pp. 190-200
- Halaban, R.¹ Zhang, W.² Bacchiocchi, A.³ Cheng, E.⁴ Parisi, F.⁵ Ariyan, S.⁶ Krauthammer, M.⁷ McCusker, J.P.⁸ Kluger, Y.⁹ Sznol, M.¹⁰

12
- 3342974363
- P. C. Chin, L. Liu, B. E. Morrison, A. Siddiq, R. R. Ratan, T. Bottiglieri, S. R. D'Mello, J. Neurochem. 2004, 90, 595-608.
- (2004) J. Neurochem. , vol.90 , pp. 595-608
- Chin, P.C.¹ Liu, L.² Morrison, B.E.³ Siddiq, A.⁴ Ratan, R.R.⁵ Bottiglieri, T.⁶ D'Mello, S.R.⁷

13
- 48849095518
- J. D. Hansen, J. Grina, B. Newhouse, M. Welch, G. Topalov, N. Littman, M. Callejo, S. Gloor, M. Martinson, E. Laird, B. J. Brandhuber, G. Vigers, T. Morales, R. Woessner, N. Randolph, J. Lyssikatos, A. Olivero, Bioorg. Med. Chem. Lett. 2008, 18, 4692-4695.
- (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 4692-4695
- Hansen, J.D.¹ Grina, J.² Newhouse, B.³ Welch, M.⁴ Topalov, G.⁵ Littman, N.⁶ Callejo, M.⁷ Gloor, S.⁸ Martinson, M.⁹ Laird, E.¹⁰ Brandhuber, B.J.¹¹ Vigers, G.¹² Morales, T.¹³ Woessner, R.¹⁴ Randolph, N.¹⁵ Lyssikatos, J.¹⁶ Olivero, A.¹⁷

14
- 70449123573
- F. A. Karreth, G. M. DeNicola, S. P. Winter, D. A. Tuveson, Mol. Cell 2009, 36, 477-486.
- (2009) Mol. Cell , vol.36 , pp. 477-486
- Karreth, F.A.¹ DeNicola, G.M.² Winter, S.P.³ Tuveson, D.A.⁴

15
- 70449995469
- M. L. Sos, S. Fischer, R. Ullrich, M. Peifer, J. M. Heuckmann, M. Koker, S. Heynck, I. Stückrath, J. Weiss, F. Fischer, K. Michel, A. Goel, L. Regales, K. A. Politi, S. Perera, M. Getlik, L. C. Heukamp, S. Ansén, T. Zander, R. Beroukhim, H. Kashkar, K. M. Shokat, W. R. Sellers, D. Rauh, C. Orr, K. P. Hoeflich, L. Friedman, K.-K. Wong, W. Pao, R. K. Thomas, Proc. Natl. Acad. Sci. USA 2009, 106, 18351-18356.
- (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 18351-18356
- Sos, M.L.¹ Fischer, S.² Ullrich, R.³ Peifer, M.⁴ Heuckmann, J.M.⁵ Koker, M.⁶ Heynck, S.⁷ Stückrath, I.⁸ Weiss, J.⁹ Fischer, F.¹⁰ Michel, K.¹¹ Goel, A.¹² Regales, L.¹³ Politi, K.A.¹⁴ Perera, S.¹⁵ Getlik, M.¹⁶ Heukamp, L.C.¹⁷ Ansén, S.¹⁸ Zander, T.¹⁹ Beroukhim, R.²⁰ more..

16
- 67651006061
- M. L. Sos, K. Michel, T. Zander, J. Weiss, P. Frommolt, M. Peifer, D. Li, R. Ullrich, M. Koker, F. Fischer, T. Shimamura, D. Rauh, C. Mermel, S. Fischer, I. Stückrath, S. Heynck, R. Beroukhim, W. Lin, W. Winckler, K. Shah, T. LaFramboise, W. F. Moriarty, M. Hanna, L. Tolosi, J. Rahnenführer, R. Verhaak, D. Chiang, G. Getz, M. Hellmich, J. Wolf, L. Girard, M. Peyton, B. A. Weir, T.-H. Chen, H. Greulich, J. Barretina, G. I. Shapiro, L. A. Garraway, A. F. Gazdar, J. D. Minna, M. Meyerson, K.-K. Wong, R. K. Thomas, J. Clin. Invest. 2009, 119, 1727-1740.
- (2009) J. Clin. Invest. , vol.119 , pp. 1727-1740
- Sos, M.L.¹ Michel, K.² Zander, T.³ Weiss, J.⁴ Frommolt, P.⁵ Peifer, M.⁶ Li, D.⁷ Ullrich, R.⁸ Koker, M.⁹ Fischer, F.¹⁰ Shimamura, T.¹¹ Rauh, D.¹² Mermel, C.¹³ Fischer, S.¹⁴ Stückrath, I.¹⁵ Heynck, S.¹⁶ Beroukhim, R.¹⁷ Lin, W.¹⁸ Winckler, W.¹⁹ Shah, K.²⁰ more..

17
- 76249108622
- M. L. Sos, H. B. Rode, S. Heynck, M. Peifer, F. Fischer, S. Klüter, V. G. Pawar, C. Reuter, J. M. Heuckmann, J. Weiss, L. Ruddigkeit, M. Rabiller, M. Koker, J. R. Simard, M. Getlik, Y. Yuza, T.-H. Chen, H. Greulich, R. K. Thomas, D. Rauh, Cancer Res. 2010, 70, 868-874.
- (2010) Cancer Res. , vol.70 , pp. 868-874
- Sos, M.L.¹ Rode, H.B.² Heynck, S.³ Peifer, M.⁴ Fischer, F.⁵ Klüter, S.⁶ Pawar, V.G.⁷ Reuter, C.⁸ Heuckmann, J.M.⁹ Weiss, J.¹⁰ Ruddigkeit, L.¹¹ Rabiller, M.¹² Koker, M.¹³ Simard, J.R.¹⁴ Getlik, M.¹⁵ Yuza, Y.¹⁶ Chen, T.-H.¹⁷ Greulich, H.¹⁸ Thomas, R.K.¹⁹ Rauh, D.²⁰ more..

18
- 3042838587
- B. W. Kramer, R. Götz, U. R. Rapp, BMC Cancer 2004, 4, 24.
- (2004) BMC Cancer , vol.4 , pp. 24
- Kramer, B.W.¹ Götz, R.² Rapp, U.R.³

19
- 67349125149
- A. J. M. Cameron, C. Escribano, A. T. Saurin, B. Kostelecky, P. J. Parker, Nat. Struct. Mol. Biol. 2009, 16, 624-630.
- (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 624-630
- Cameron, A.J.M.¹ Escribano, C.² Saurin, A.T.³ Kostelecky, B.⁴ Parker, P.J.⁵

20
- 67650337799
- T. Okuzumi, D. Fiedler, C. Zhang, D. C. Gray, B. Aizenstein, R. Hoffman, K. M. Shokat, Nat. Chem. Biol. 2009, 5, 484-493.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 484-493
- Okuzumi, T.¹ Fiedler, D.² Zhang, C.³ Gray, D.C.⁴ Aizenstein, B.⁵ Hoffman, R.⁶ Shokat, K.M.⁷

21
- 33845730781
- A. J. King, D. R. Patrick, R. S. Batorsky, M. L. Ho, H. T. Do, S. Y. Zhang, R. Kumar, D. W. Rusnak, A. K. Takle, D. M. Wilson, E. Hugger, L. Wang, F. Karreth, J. C. Lougheed, J. Lee, D. Chau, T. J. Stout, E. W. May, C. M. Rominger, M. D. Schaber, L. Luo, A. S. Lakdawala, J. L. Adams, R. G. Contractor, K. S. M. Smalley, M. Herlyn, M. M. Morrissey, D. A. Tuveson, P. S. Huang, Cancer Res. 2006, 66, 11100-11105.
- (2006) Cancer Res. , vol.66 , pp. 11100-11105
- King, A.J.¹ Patrick, D.R.² Batorsky, R.S.³ Ho, M.L.⁴ Do, H.T.⁵ Zhang, S.Y.⁶ Kumar, R.⁷ Rusnak, D.W.⁸ Takle, A.K.⁹ Wilson, D.M.¹⁰ Hugger, E.¹¹ Wang, L.¹² Karreth, F.¹³ Lougheed, J.C.¹⁴ Lee, J.¹⁵ Chau, D.¹⁶ Stout, T.J.¹⁷ May, E.W.¹⁸ Rominger, C.M.¹⁹ Schaber, M.D.²⁰ more..

22
- 37349077948
- V. Khazak, I. Astsaturov, I. G. Serebriiskii, E. A. Golemis, Expert Opin. Ther. Targets 2007, 11, 1587-1609.
- (2007) Expert Opin. Ther. Targets , vol.11 , pp. 1587-1609
- Khazak, V.¹ Astsaturov, I.² Serebriiskii, I.G.³ Golemis, E.A.⁴

23
- 27544453376
- V. Emuss, M. Garnett, C. Mason, R. Marais, Cancer Res. 2005, 65, 9719-9726.
- (2005) Cancer Res. , vol.65 , pp. 9719-9726
- Emuss, V.¹ Garnett, M.² Mason, C.³ Marais, R.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.