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Volumn 5, Issue 7, 2010, Pages

The chemopreventive effects of Protandim: Modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DIMETHYLBENZ[A]ANTHRACENE; MANGANESE SUPEROXIDE DISMUTASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTANDIM; PROTEIN BAX; PROTEIN P53; UNCLASSIFIED DRUG; HERBACEOUS AGENT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

EID: 77955617571     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011902     Document Type: Article
Times cited : (30)

References (26)
  • 1
    • 18144382261 scopus 로고    scopus 로고
    • P53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase
    • Zhao Y, Chaiswing L, Velez JM, Batinic-Haberle I, Colburn NH, et al. (2005) p53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase. Cancer Res 65: 3745-3750.
    • (2005) Cancer Res , vol.65 , pp. 3745-3750
    • Zhao, Y.1    Chaiswing, L.2    Velez, J.M.3    Batinic-Haberle, I.4    Colburn, N.H.5
  • 3
    • 25644458432 scopus 로고    scopus 로고
    • Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenographs in immunodeficient mice
    • Avila GE, Zheng X, Cui XX, Ryan AD, Hansson A, et al. (2005) Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenographs in immunodeficient mice. J Pharmacol Exp Ther 15: 170-187.
    • (2005) J Pharmacol Exp Ther , vol.15 , pp. 170-187
    • Avila, G.E.1    Zheng, X.2    Cui, X.X.3    Ryan, A.D.4    Hansson, A.5
  • 4
    • 33745208935 scopus 로고    scopus 로고
    • Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate cancer LnCap cells cultured in vitro or grown as xenongraft tumors in immunodeficient mice
    • Zheng X, Chang RL, Cui XX, Avila GE, Hebbar V, et al. (2006) Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate cancer LnCap cells cultured in vitro or grown as xenongraft tumors in immunodeficient mice. Clin Cancer Res 1: 3444-3451.
    • (2006) Clin Cancer Res , vol.1 , pp. 3444-3451
    • Zheng, X.1    Chang, R.L.2    Cui, X.X.3    Avila, G.E.4    Hebbar, V.5
  • 5
    • 37249084581 scopus 로고    scopus 로고
    • Low dose 12-O-tetradecanoylphorbol-13-acetate enhances tumor necrosis factor related apoptosis-inducing ligand induced apoptosis in prostate cancer cells
    • Zhang X, Li W, Olumi AF (2007) Low dose 12-O-tetradecanoylphorbol-13-acetate enhances tumor necrosis factor related apoptosis-inducing ligand induced apoptosis in prostate cancer cells. Clin Cancer Res 13: 7181-7190.
    • (2007) Clin Cancer Res , vol.13 , pp. 7181-7190
    • Zhang, X.1    Li, W.2    Olumi, A.F.3
  • 7
    • 0033229866 scopus 로고    scopus 로고
    • P53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
    • Li P-F, Dietz R, von Harsdorf R (1999) p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J 18: 6027-6036.
    • (1999) EMBO J , vol.18 , pp. 6027-6036
    • Li, P.-F.1    Dietz, R.2    von Harsdorf, R.3
  • 8
    • 36849084779 scopus 로고    scopus 로고
    • CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice
    • Tang X, Zhu Y, Han L, Kim AL, Kopelovich L, et al. (2007) CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice. J Clin Invest 117: 3753-3764.
    • (2007) J Clin Invest , vol.117 , pp. 3753-3764
    • Tang, X.1    Zhu, Y.2    Han, L.3    Kim, A.L.4    Kopelovich, L.5
  • 9
    • 67649224733 scopus 로고    scopus 로고
    • Protandim, a fundamentally new approach in chemoprevention using mouse two-stage skin carcinogenesis as a model
    • doi:10.1371/journal.pone.0005284
    • Liu J, Gu X, Robbins D, Li G, Shi R, et al. (2009) Protandim, a fundamentally new approach in chemoprevention using mouse two-stage skin carcinogenesis as a model. PLoS One 4: e5284. doi:10.1371/journal.pone.0005284.
    • (2009) PLoS One , vol.4
    • Liu, J.1    Gu, X.2    Robbins, D.3    Li, G.4    Shi, R.5
  • 10
    • 30344461640 scopus 로고    scopus 로고
    • The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy
    • Nelson SK, Bose SK, Grunwald GK, Myhill P, McCord JM (2006) The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy. Free Radic Biol Med 40: 341-347.
    • (2006) Free Radic Biol Med , vol.40 , pp. 341-347
    • Nelson, S.K.1    Bose, S.K.2    Grunwald, G.K.3    Myhill, P.4    McCord, J.M.5
  • 11
    • 0032715311 scopus 로고    scopus 로고
    • Silymarin suppresses TNF-induced Activation of NF-(kappa) B, cjun N-terminal kinase and apoptosis
    • Manna SK, Mukhopadhyay A, Van NT, Aggarwal BB (1999) Silymarin suppresses TNF-induced Activation of NF-(kappa) B, cjun N-terminal kinase and apoptosis. J Immunol 163: 6800-6809.
    • (1999) J Immunol , vol.163 , pp. 6800-6809
    • Manna, S.K.1    Mukhopadhyay, A.2    Van, N.T.3    Aggarwal, B.B.4
  • 12
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM, Sandstorm PA (1994) Oxidative stress as a mediator of apoptosis. Immunol Today 15: 7.
    • (1994) Immunol Today , vol.15 , pp. 7
    • Buttke, T.M.1    Sandstorm, P.A.2
  • 13
    • 62149137729 scopus 로고    scopus 로고
    • Bacopa monniera leaf extract ameliorates hypobaric hypoxia induced spatial memory impairment
    • Hota SK, Barhwal K, Baitharu I, Prasad D, Singh SB, et al. (2009) Bacopa monniera leaf extract ameliorates hypobaric hypoxia induced spatial memory impairment. Neurobiol Dis 34: 23-29.
    • (2009) Neurobiol Dis , vol.34 , pp. 23-29
    • Hota, S.K.1    Barhwal, K.2    Baitharu, I.3    Prasad, D.4    Singh, S.B.5
  • 14
    • 0038548415 scopus 로고    scopus 로고
    • Comparative study of antioxidant properties and cytoprotective activity of flavonoids
    • Potapovich AI, Kostyuk VA (2003) Comparative study of antioxidant properties and cytoprotective activity of flavonoids. Biochem (Mosc) 68: 514-519.
    • (2003) Biochem (Mosc) , vol.68 , pp. 514-519
    • Potapovich, A.I.1    Kostyuk, V.A.2
  • 15
    • 0033840501 scopus 로고    scopus 로고
    • Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse
    • Chaurasia SS, Panda S, Kar A (2000) Withania somnifera root extract in the regulation of lead-induced oxidative damage in male mouse. Pharmacol Res 6: 663-666.
    • (2000) Pharmacol Res , vol.6 , pp. 663-666
    • Chaurasia, S.S.1    Panda, S.2    Kar, A.3
  • 16
    • 33745056543 scopus 로고    scopus 로고
    • Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion induced apoptosis by bcl-2-mitochondria-ROS-iNos pathway
    • Cheng J, Tang XQ, Zhi JL, Cui Y, Yu HM, et al. (2006) Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion induced apoptosis by bcl-2-mitochondria-ROS-iNos pathway. Apoptosis 11: 943-953.
    • (2006) Apoptosis , vol.11 , pp. 943-953
    • Cheng, J.1    Tang, X.Q.2    Zhi, J.L.3    Cui, Y.4    Yu, H.M.5
  • 17
    • 0037259650 scopus 로고    scopus 로고
    • Detection of the content and activity of the transcription factor AP-1 in a multistage skin carcinogenesis model
    • Zhao Y, St Clair DK (2003) Detection of the content and activity of the transcription factor AP-1 in a multistage skin carcinogenesis model. Methods Mol Biol 218: 177-184.
    • (2003) Methods Mol Biol , vol.218 , pp. 177-184
    • Zhao, Y.1    Clair, D.K.2
  • 18
    • 85047698438 scopus 로고    scopus 로고
    • Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoterinduced alterations in AP-1 and p53-mediated pathways in a skin cancer model
    • Zhao Y, Oberley TD, Chaiswing L, Lin S, Epstein CJ, et al. (2002) Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoterinduced alterations in AP-1 and p53-mediated pathways in a skin cancer model.Oncogene 21: 3836-3846.
    • (2002) Oncogene , vol.21 , pp. 3836-3846
    • Zhao, Y.1    Oberley, T.D.2    Chaiswing, L.3    Lin, S.4    Epstein, C.J.5
  • 20
    • 14844320063 scopus 로고    scopus 로고
    • Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release and caspase activation
    • Katiyar SK, Roy AM, Baliga MS (2005) Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release and caspase activation. Mol Cancer Ther 4: 207-216.
    • (2005) Mol Cancer Ther , vol.4 , pp. 207-216
    • Katiyar, S.K.1    Roy, A.M.2    Baliga, M.S.3
  • 21
    • 59849108790 scopus 로고    scopus 로고
    • The p53-p66shc-manganese superoxide dismutase (MnSOD) network: A mitochondrial intrigue to generate reactive oxygen species
    • Pani G, Koch OR, Galeotti T (2009) The p53-p66shc-manganese superoxide dismutase (MnSOD) network: A mitochondrial intrigue to generate reactive oxygen species. The International J Biochem & Cell Biol 41: 1002-1005.
    • (2009) The International J Biochem & Cell Biol , vol.41 , pp. 1002-1005
    • Pani, G.1    Koch, O.R.2    Galeotti, T.3
  • 22
    • 2342455198 scopus 로고    scopus 로고
    • Mitochondrial superoxide dismutase: A promising target for new anticancer therapies
    • Pani G, Colavitti R, Bedogni B, Fusco S, Ferraro D, et al. (2004) Mitochondrial superoxide dismutase: a promising target for new anticancer therapies. Curr Med Chem 11: 1299-1308.
    • (2004) Curr Med Chem , vol.11 , pp. 1299-1308
    • Pani, G.1    Colavitti, R.2    Bedogni, B.3    Fusco, S.4    Ferraro, D.5
  • 23
    • 41149105243 scopus 로고    scopus 로고
    • Ros and p53: A versatile partnership
    • Liu B, Chen Y, Clair DK St (2008) Ros and p53: a versatile partnership. Free Radic Biol Med 44: 1529-1535.
    • (2008) Free Radic Biol Med , vol.44 , pp. 1529-1535
    • Liu, B.1    Chen, Y.2    Clair, D.K.3
  • 24
    • 77955617955 scopus 로고    scopus 로고
    • Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
    • Marchenko ND, Zaika A, Moll UM (2005) Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 280: 19166-19176.
    • (2005) J Biol Chem , vol.280 , pp. 19166-19176
    • Marchenko, N.D.1    Zaika, A.2    Moll, U.M.3
  • 25
    • 0034068601 scopus 로고    scopus 로고
    • Mitochondrial control of cell death
    • Kroemer G, Reed JC (2000) Mitochondrial control of cell death. Nat Med 6: 513-519.
    • (2000) Nat Med , vol.6 , pp. 513-519
    • Kroemer, G.1    Reed, J.C.2
  • 26
    • 33746819118 scopus 로고    scopus 로고
    • Specificity Protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression
    • Dhar SK, Xu Y, Chen Y, St. Clair DK (2006) Specificity Protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression. J Biol Chem 281: 21698-21709.
    • (2006) J Biol Chem , vol.281 , pp. 21698-21709
    • Dhar, S.K.1    Xu, Y.2    Chen, Y.3    Clair, D.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.