Benzo[a]pyrene-induced neurobehavioral function and neurotransmitter alterations in coke oven workers

Occupational and Environmental Medicine

Volumn 67, Issue 7, 2010, Pages 444-448

  Niu, Qiao ^a   Zhang, Hongmei ^a   Li, Xin ^b   Li, Meiqin ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

^b TAIYUAN IRON AND STEEL GROUP CO LTD   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; 4 AMINOBUTYRIC ACID; 5 HYDROXYINDOLEACETIC ACID; ACETYLCHOLINE; ASPARTIC ACID; BENZO[A]PYRENE; CHOLINE; DOPAMINE; HOMOVANILLIC ACID; NEUROTRANSMITTER; NORADRENALIN; SEROTONIN;

ADULT; AIRBORNE PARTICLE; ARTICLE; BLOOD LEVEL; COGNITION; CONTROLLED STUDY; EMOTION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LEARNING; MAJOR CLINICAL STUDY; MALE; MEMORY; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; QUESTIONNAIRE; SPECTROPHOTOMETRY; WORK ENVIRONMENT; WORKER;

ADULT; AIR POLLUTANTS, OCCUPATIONAL; BENZO(A)PYRENE; CASE-CONTROL STUDIES; CHINA; COKE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; NEUROTRANSMITTER AGENTS; OCCUPATIONAL EXPOSURE; POLYCYCLIC HYDROCARBONS, AROMATIC; PYRENES; QUESTIONNAIRES;

EID: 77955596321     PISSN: 13510711     EISSN: 14707926     Source Type: Journal    
DOI: 10.1136/oem.2009.047969     Document Type: Article

References (21)

1. Majchrzak R, Sroczyński J, Chełmecka E. [Evaluation of the nervous system in workers in the furnace and coal divisions of the coke-producing plants]. Med Pr 1990;41:108-13.
2. Dayal H, Gupta S, Trieff N, et al. Symptom clusters in a community with chronic exposure to chemicals in two superfund sites. Arch Environ Health 1995;50:108-11.
3. Kilburn KH, Warshaw RH. Neurotoxic effects from residential exposure to chemicals from an oil reprocessing facility and superfund site. Neurotoxicol Teratol 1995;17:89-102.
4. Mendola P, Selevan SG, Gutter S, et al. Environmental factors associated with a spectrum of neurodevelopmental deficits. Ment Retard Dev Disabil Res Rev 2002;8:188-97.
5. Zhang HM, Nie JS, Wang F, et al. Effects of benzo[a]pyrene on autonomic nervous system of coke oven workers. J Occup Health 2008;50:308-16.
6. Nie JS. [Relationship of benzo[a]pyrene neurotoxicity and CYP1A1 gene polymorphism]. shanxi medical university phD. Degree paper 2007:20-26.
7. Li XH, Leng SG, Guo J, et al. [An improved high performance liquid chromatography method for determination of 1-hydroxypyrene in urine]. J Hygiene Res 2003;32:616-17.
8. Ruan GH, Zheng LX, Wu QE, et al. [Study on monoamine neurotransmitters in rat serum and brain tissue by high performance liquid chromatography with electrochemical detection]. J Hygiene Res 2006;35:146-9.
9. Wu QE, Zheng LX, Ruan GH, et al. [Determination of the amino acids in rat brain by high-performance liquid chromatography and fluorescence detection]. Fudan Univ J Med Sci 2005;32:355-8.
10. Saunders CR, Shockley DC, Knuckles ME. Behavioral effects induced by acute exposure to benzo(a)pyrene in F-344 rats. Neurotox Res 2001;3:557-79.
11. Saunders CR, Ramesh A, Shockley DC. Modulation of neurotoxic behavior in F-344 rats by temporal disposition of benzo(a)pyrene. Toxicol Lett 2002;129:33-45.
12. Saunders CR, Shockley DC, Knuckles ME. Fluoranthene-induced neurobehavioral toxicity in F-344 rats. Int J Toxicol 2003;22:263-76.
13. Anderson H, Lindqvist E, Westerholm R, et al. Neurotoxic effects of fractionated diesel exhausts following microinjections in rat hippocampus and striatum. Environ Res 1998;76:41-51.
14. Jayasekara S, Sharma RP, Drown DB. Effects of benzo[a]pyrene on steady-state levels of biogenic amines and metabolizing enzymes in mouse brain regions. Ecotoxicol Environ Saf 1992;24:1-12.
15. Dasgupta PS, Lahiri T. Alteration of brain catecholamines during growth of benzo(a) pyrene induced murine fibrosarcoma. Neoplasma 1992;39:163-65.
16. Konstandi M, Harkitis P, Thermos K, et al. Modification of inherent and drug-induced dopaminergic activity after exposure to benzo(alpha)pyrene. Neurotoxicology 2007;28:860-7.
17. Stephanou P, Konstandi M, Pappas P, et al. Alterations in central monoaminergic neurotransmission induced by polycyclic aromatic hydrocarbons in rats. Eur J Drug Metab Pharmacokinet 1998;23:475-81.
18. Zhang HM, Nie Js, X CE, et al. Influence of benzo[a]pyrene on rats'learning and memory and amino acid neurotransmitters in hippocampus. Chin J Ind Hyg Occup Dis 2008;26:546-8.
19. Cunha I, García LM, Guilhermino L. Sea-urchin (Paracentrotus lividus) glutathione S-transferases and cholinesterase activities as biomarkers of environmental contamination. J Environ Monit 2005;7:288-94.
20. Akcha F, Izuel C, Venier P, et al. Enzymatic biomarker measurement and study of DNA adduct formation in benzo[a]pyrene-contaminated mussels, mytilus galloprovincialis. Aquat Toxicol 2000;49:269-87.
21. Jett DA, Navoa RV, Lyons MA Jr. Additive inhibitory action of chlorpyrifos and polycyclic aromatic hydrocarbons on acetylcholinesterase activity in vitro. Toxicol Lett 1999;105:223-9.