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Volumn 11, Issue 8, 2010, Pages 1940-1947

PEGylated polyamidoamine dendrimers with bis-aryl hydrazone linkages for enhanced gene delivery

Author keywords

[No Author keywords available]

Indexed keywords

BUFFERING CAPACITIES; CYTOCOMPATIBILITY; DNA PLASMIDS; FUNCTIONALIZED DENDRIMERS; GENE DELIVERY; GENE TRANSFECTION; HYDRAZONE BONDS; HYDRAZONES; LOW WEIGHT; METHOXYPOLYETHYLENE GLYCOL; MONOFUNCTIONAL; PAMAM DENDRIMER; PEGYLATION; POLYAMIDOAMINE DENDRIMERS; SURFACE MODIFICATION; TWO-STEP PROCEDURE;

EID: 77955579970     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm100589g     Document Type: Article
Times cited : (85)

References (41)
  • 1
    • 0036740007 scopus 로고    scopus 로고
    • Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier
    • Lim, Y. B.; Kim, S. M.; Suh, H.; Park, J. S. Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier Bioconjugate Chem. 2002, 13 (5) 952-7
    • (2002) Bioconjugate Chem. , vol.13 , Issue.5 , pp. 952-7
    • Lim, Y.B.1    Kim, S.M.2    Suh, H.3    Park, J.S.4
  • 2
    • 0037221558 scopus 로고    scopus 로고
    • Cationic lipid and polymer-based gene delivery to human pancreatic islets
    • Mahato, R. I.; Henry, J.; Narang, A. S.; Sabek, O.; Fraga, D.; Kotb, M.; Gaber, A. O. Cationic lipid and polymer-based gene delivery to human pancreatic islets Mol. Ther. 2003, 7 (1) 89-100
    • (2003) Mol. Ther. , vol.7 , Issue.1 , pp. 89-100
    • Mahato, R.I.1    Henry, J.2    Narang, A.S.3    Sabek, O.4    Fraga, D.5    Kotb, M.6    Gaber, A.O.7
  • 3
    • 0034019945 scopus 로고    scopus 로고
    • Cationic polymer based gene delivery systems
    • De Smedt, S. C.; Demeester, J.; Hennink, W. E. Cationic polymer based gene delivery systems Pharm. Res. 2000, 17 (2) 113-26
    • (2000) Pharm. Res. , vol.17 , Issue.2 , pp. 113-26
    • De Smedt, S.C.1    Demeester, J.2    Hennink, W.E.3
  • 5
    • 0003008343 scopus 로고    scopus 로고
    • Synthetic DNA delivery systems
    • Luo, D.; Saltzman, W. M. Synthetic DNA delivery systems Nat. Biotechnol. 2000, 18 (1) 33-37
    • (2000) Nat. Biotechnol. , vol.18 , Issue.1 , pp. 33-37
    • Luo, D.1    Saltzman, W.M.2
  • 7
    • 0037423770 scopus 로고    scopus 로고
    • Prevention of autoimmune insulitis by delivery of a chimeric plasmid encoding interleukin-4 and interleukin-10
    • Lee, M.; Ko, K. S.; Oh, S.; Kim, S. W. Prevention of autoimmune insulitis by delivery of a chimeric plasmid encoding interleukin-4 and interleukin-10 J. Controlled Release 2003, 88 (2) 333-42
    • (2003) J. Controlled Release , vol.88 , Issue.2 , pp. 333-42
    • Lee, M.1    Ko, K.S.2    Oh, S.3    Kim, S.W.4
  • 9
    • 0344466792 scopus 로고    scopus 로고
    • Designing dendrimers for drug delivery
    • Liu, M.; Frechet, J. M. J. Designing dendrimers for drug delivery Pharm. Sci. Technol. Today 1999, 2 (10) 393-401
    • (1999) Pharm. Sci. Technol. Today , vol.2 , Issue.10 , pp. 393-401
    • Liu, M.1    Frechet, J.M.J.2
  • 10
    • 0034004284 scopus 로고    scopus 로고
    • Application of membrane-based dendrimer/DNA complexes for solid phase transfection in vitro and in vivo
    • Bielinska, A. U.; Yen, A.; Wu, H. L.; Zahos, K. M.; Sun, R.; Weiner, N. D.; Baker, J. R., Jr.; Roessler, B. J. Application of membrane-based dendrimer/DNA complexes for solid phase transfection in vitro and in vivo Biomaterials 2000, 21 (9) 877-887
    • (2000) Biomaterials , vol.21 , Issue.9 , pp. 877-887
    • Bielinska, A.U.1    Yen, A.2    Wu, H.L.3    Zahos, K.M.4    Sun, R.5    Weiner, N.D.6    Baker Jr., J.R.7    Roessler, B.J.8
  • 12
    • 0027655718 scopus 로고
    • Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
    • Haensler, J.; Szoka, F. C., Jr. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture Bioconjugate Chem. 1993, 4 (5) 372-9
    • (1993) Bioconjugate Chem. , vol.4 , Issue.5 , pp. 372-9
    • Haensler, J.1    Szoka Jr., F.C.2
  • 13
    • 0030743086 scopus 로고    scopus 로고
    • The interaction of plasmid DNA with polyamidoamine dendrimers: Mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA
    • Bielinska, A. U.; Kukowska-Latallo, J. F.; Baker, J. R., Jr. The interaction of plasmid DNA with polyamidoamine dendrimers: mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA Biochim. Biophys. Acta 1997, 1353 (2) 180-90
    • (1997) Biochim. Biophys. Acta , vol.1353 , Issue.2 , pp. 180-90
    • Bielinska, A.U.1    Kukowska-Latallo, J.F.2    Baker Jr., J.R.3
  • 14
    • 14344262752 scopus 로고    scopus 로고
    • Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles
    • Braun, C. S.; Vetro, J. A.; Tomalia, D. A.; Koe, G. S.; Koe, J. G.; Middaugh, C. R. Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles J. Pharm. Sci. 2005, 94 (2) 423-436
    • (2005) J. Pharm. Sci. , vol.94 , Issue.2 , pp. 423-436
    • Braun, C.S.1    Vetro, J.A.2    Tomalia, D.A.3    Koe, G.S.4    Koe, J.G.5    Middaugh, C.R.6
  • 15
    • 0034326297 scopus 로고    scopus 로고
    • Enhanced delivery of antisense oligonucleotides with fluorophore- conjugated PAMAM dendrimers
    • Yoo, H.; Juliano, R. L. Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers Nucleic Acids Res. 2000, 28 (21) 4225-31
    • (2000) Nucleic Acids Res. , vol.28 , Issue.21 , pp. 4225-31
    • Yoo, H.1    Juliano, R.L.2
  • 16
    • 25444492244 scopus 로고    scopus 로고
    • Preparation of efficient gene carriers using a polyamidoamine dendron-bearing lipid: Improvement of serum resistance
    • Takahashi, T.; Harada, A.; Emi, N.; Kono, K. Preparation of efficient gene carriers using a polyamidoamine dendron-bearing lipid: improvement of serum resistance Bioconjugate Chem. 2005, 16 (5) 1160-1165
    • (2005) Bioconjugate Chem. , vol.16 , Issue.5 , pp. 1160-1165
    • Takahashi, T.1    Harada, A.2    Emi, N.3    Kono, K.4
  • 17
    • 0242414440 scopus 로고    scopus 로고
    • Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
    • Sonawane, N. D.; Szoka, F. C., Jr.; Verkman, A. S. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes J. Biol. Chem. 2003, 278 (45) 44826-44831
    • (2003) J. Biol. Chem. , vol.278 , Issue.45 , pp. 44826-44831
    • Sonawane, N.D.1    Szoka Jr., F.C.2    Verkman, A.S.3
  • 18
    • 36849082611 scopus 로고    scopus 로고
    • Conjugation of polyamidoamine dendrimers on biodegradable microparticles for nonviral gene delivery
    • Zhang, X. Q.; Intra, J.; Salem, A. K. Conjugation of polyamidoamine dendrimers on biodegradable microparticles for nonviral gene delivery Bioconjugate Chem 2007, 18 (6) 2068-76
    • (2007) Bioconjugate Chem , vol.18 , Issue.6 , pp. 2068-76
    • Zhang, X.Q.1    Intra, J.2    Salem, A.K.3
  • 19
    • 0022555867 scopus 로고
    • Acidification of the endocytic and exocytic pathways
    • Mellman, I.; Fuchs, R.; Helenius, A. Acidification of the endocytic and exocytic pathways Annu. Rev. Biochem. 1986, 55, 663-700
    • (1986) Annu. Rev. Biochem. , vol.55 , pp. 663-700
    • Mellman, I.1    Fuchs, R.2    Helenius, A.3
  • 20
    • 70350063814 scopus 로고    scopus 로고
    • Bioreducible hyperbranched poly(amido amine)s for gene delivery
    • Chen, J.; Wu, C.; Oupicky, D. Bioreducible hyperbranched poly(amido amine)s for gene delivery Biomacromolecules 2009, 10 (10) 2921-7
    • (2009) Biomacromolecules , vol.10 , Issue.10 , pp. 2921-7
    • Chen, J.1    Wu, C.2    Oupicky, D.3
  • 21
    • 56449116768 scopus 로고    scopus 로고
    • Biodegradable PAMAM ester for enhanced transfection efficiency with low cytotoxicity
    • Nam, H. Y.; Nam, K.; Hahn, H. J.; Kim, B. H.; Lim, H. J.; Kim, H. J.; Choi, J. S.; Park, J. S. Biodegradable PAMAM ester for enhanced transfection efficiency with low cytotoxicity Biomaterials 2009, 30 (4) 665-73
    • (2009) Biomaterials , vol.30 , Issue.4 , pp. 665-73
    • Nam, H.Y.1    Nam, K.2    Hahn, H.J.3    Kim, B.H.4    Lim, H.J.5    Kim, H.J.6    Choi, J.S.7    Park, J.S.8
  • 22
    • 65249141045 scopus 로고    scopus 로고
    • Polyamidoamine dendrimers with a modified pentaerythritol core having high efficiency and low cytotoxicity as gene carriers
    • Wang, Y.; Kong, W.; Song, Y.; Duan, Y.; Wang, L.; Steinhoff, G.; Kong, D.; Yu, Y. Polyamidoamine dendrimers with a modified pentaerythritol core having high efficiency and low cytotoxicity as gene carriers Biomacromolecules 2009, 10 (3) 617-622
    • (2009) Biomacromolecules , vol.10 , Issue.3 , pp. 617-622
    • Wang, Y.1    Kong, W.2    Song, Y.3    Duan, Y.4    Wang, L.5    Steinhoff, G.6    Kong, D.7    Yu, Y.8
  • 24
    • 69249229901 scopus 로고    scopus 로고
    • Star-shaped polymers having PEO arms
    • Lapienis, G. Star-shaped polymers having PEO arms Prog. Polym. Sci. 2009, 34 (9) 852-892
    • (2009) Prog. Polym. Sci. , vol.34 , Issue.9 , pp. 852-892
    • Lapienis, G.1
  • 25
    • 33947625559 scopus 로고    scopus 로고
    • Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
    • Huang, R.-Q.; Qu, Y.-H.; Ke, W.-L.; Zhu, J.-H.; Pei, Y.-Y.; Chen, J. Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer FASEB J. 2007, 21 (4) 1117-1125
    • (2007) FASEB J. , vol.21 , Issue.4 , pp. 1117-1125
    • Huang, R.-Q.1    Qu, Y.-H.2    Ke, W.-L.3    Zhu, J.-H.4    Pei, Y.-Y.5    Chen, J.6
  • 26
    • 75149197230 scopus 로고    scopus 로고
    • Synthesis and characterization of thermoresponsive polyamidoamine- polyethylene glycol-poly (d, l-lactide) (PAMAM-PEG-PDLLA) core-shell nanoparticles
    • Kailasan, A.; Yuan, Q.; Yang, H. Synthesis and characterization of thermoresponsive polyamidoamine-polyethylene glycol-poly (d, l-lactide) (PAMAM-PEG-PDLLA) core-shell nanoparticles Acta Biomater. 2010, 6 (3) 1131-1139
    • (2010) Acta Biomater. , vol.6 , Issue.3 , pp. 1131-1139
    • Kailasan, A.1    Yuan, Q.2    Yang, H.3
  • 27
    • 50849109488 scopus 로고    scopus 로고
    • Encapsulation and extended release of anti-cancer anastrozole by stealth nanoparticles
    • Sarkar, K.; Yang, H. Encapsulation and extended release of anti-cancer anastrozole by stealth nanoparticles Drug Delivery 2008, 15 (5) 343-6
    • (2008) Drug Delivery , vol.15 , Issue.5 , pp. 343-6
    • Sarkar, K.1    Yang, H.2
  • 28
    • 33645102601 scopus 로고    scopus 로고
    • In vitro enzymatic stability of dendritic peptides
    • Yang, H.; Lopina, S. T. In vitro enzymatic stability of dendritic peptides J. Biomed. Mater. Res., Part A 2006, 76A (2) 398-407
    • (2006) J. Biomed. Mater. Res., Part A , vol.76 , Issue.2 , pp. 398-407
    • Yang, H.1    Lopina, S.T.2
  • 29
    • 41049095418 scopus 로고    scopus 로고
    • Stealth dendrimers for drug delivery: Correlation between PEGylation, cytocompatibility, and drug payload
    • Yang, H.; Lopina, S. T.; DiPersio, L. P.; Schmidt, S. P. Stealth dendrimers for drug delivery: correlation between PEGylation, cytocompatibility, and drug payload J. Mater. Sci.: Mater. Med. 2008, 19 (5) 1991-7
    • (2008) J. Mater. Sci.: Mater. Med. , vol.19 , Issue.5 , pp. 1991-7
    • Yang, H.1    Lopina, S.T.2    Dipersio, L.P.3    Schmidt, S.P.4
  • 31
    • 38749150591 scopus 로고    scopus 로고
    • Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin
    • Kono, K.; Kojima, C.; Hayashi, N.; Nishisaka, E.; Kiura, K.; Watarai, S.; Harada, A. Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin Biomaterials 2008, 29 (11) 1664-75
    • (2008) Biomaterials , vol.29 , Issue.11 , pp. 1664-75
    • Kono, K.1    Kojima, C.2    Hayashi, N.3    Nishisaka, E.4    Kiura, K.5    Watarai, S.6    Harada, A.7
  • 32
    • 0037161405 scopus 로고    scopus 로고
    • Polyethylene glycol-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery
    • Luo, D.; Haverstick, K.; Belcheva, N.; Han, E.; Saltzman, W. M. Polyethylene glycol-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery Macromolecules 2002, 35 (9) 3456-3462
    • (2002) Macromolecules , vol.35 , Issue.9 , pp. 3456-3462
    • Luo, D.1    Haverstick, K.2    Belcheva, N.3    Han, E.4    Saltzman, W.M.5
  • 33
    • 72149101909 scopus 로고    scopus 로고
    • PEG-conjugated PAMAM dendrimers mediate efficient intramuscular gene expression
    • Qi, R.; Gao, Y.; Tang, Y.; He, R. R.; Liu, T. L.; He, Y.; Sun, S.; Li, B. Y.; Li, Y. B.; Liu, G. PEG-conjugated PAMAM dendrimers mediate efficient intramuscular gene expression AAPS J. 2009, 11 (3) 395-405
    • (2009) AAPS J. , vol.11 , Issue.3 , pp. 395-405
    • Qi, R.1    Gao, Y.2    Tang, Y.3    He, R.R.4    Liu, T.L.5    He, Y.6    Sun, S.7    Li, B.Y.8    Li, Y.B.9    Liu, G.10
  • 34
    • 9744281157 scopus 로고    scopus 로고
    • PAMAM-PEG-PAMAM: Novel triblock copolymer as a biocompatible and efficient gene delivery carrier
    • Kim, T. I.; Seo, H. J.; Choi, J. S.; Jang, H. S.; Baek, J. U.; Kim, K.; Park, J. S. PAMAM-PEG-PAMAM: novel triblock copolymer as a biocompatible and efficient gene delivery carrier Biomacromolecules 2004, 5 (6) 2487-92
    • (2004) Biomacromolecules , vol.5 , Issue.6 , pp. 2487-92
    • Kim, T.I.1    Seo, H.J.2    Choi, J.S.3    Jang, H.S.4    Baek, J.U.5    Kim, K.6    Park, J.S.7
  • 35
    • 34250293129 scopus 로고
    • A theoretical and experimental study of hydrazone protonation centers
    • Zverev, V. V.; Pylaeva, T. N.; Stolyarov, A. P.; Kitaev, Y. P. A theoretical and experimental study of hydrazone protonation centers Russ. Chem. Bull. 1977, 26 (6) 1175-1180
    • (1977) Russ. Chem. Bull. , vol.26 , Issue.6 , pp. 1175-1180
    • Zverev, V.V.1    Pylaeva, T.N.2    Stolyarov, A.P.3    Kitaev, Y.P.4
  • 36
    • 0029833422 scopus 로고    scopus 로고
    • Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
    • Kinsella, T. M.; Nolan, G. P. Episomal vectors rapidly and stably produce high-titer recombinant retrovirus Hum. Gene Ther. 1996, 7 (12) 1405-13
    • (1996) Hum. Gene Ther. , vol.7 , Issue.12 , pp. 1405-13
    • Kinsella, T.M.1    Nolan, G.P.2
  • 37
    • 0035490884 scopus 로고    scopus 로고
    • The endocytic pathway: A mosaic of domains
    • Gruenberg, J. The endocytic pathway: a mosaic of domains Nat. Rev. Mol. Cell Biol. 2001, 2 (10) 721-30
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , Issue.10 , pp. 721-30
    • Gruenberg, J.1
  • 38
    • 0028566272 scopus 로고
    • MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma
    • Yeudall, W. A.; Crawford, R. Y.; Ensley, J. F.; Robbins, K. C. MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma Carcinogenesis 1994, 15 (12) 2683-6
    • (1994) Carcinogenesis , vol.15 , Issue.12 , pp. 2683-6
    • Yeudall, W.A.1    Crawford, R.Y.2    Ensley, J.F.3    Robbins, K.C.4
  • 39
    • 35548969004 scopus 로고    scopus 로고
    • Synthesis and characterization of nanoscale dendritic RGD clusters for potential applications in tissue engineering and drug delivery
    • Yang, H.; Kao, J. W. Synthesis and characterization of nanoscale dendritic RGD clusters for potential applications in tissue engineering and drug delivery Int. J. Nanomed. 2007, 2 (1) 89-99
    • (2007) Int. J. Nanomed. , vol.2 , Issue.1 , pp. 89-99
    • Yang, H.1    Kao, J.W.2
  • 40
    • 0031829748 scopus 로고    scopus 로고
    • Slab-gel and capillary electrophoretic characterization of polyamidoamine dendrimers
    • Brothers, H. M., II; Piehler, L. T.; Tomalia, D. A. Slab-gel and capillary electrophoretic characterization of polyamidoamine dendrimers J. Chromatogr., A 1998, 814, 233-246
    • (1998) J. Chromatogr., A , vol.814 , pp. 233-246
    • Brothers, H.M.I.I.1    Piehler, L.T.2    Tomalia, D.A.3
  • 41
    • 15744388668 scopus 로고    scopus 로고
    • Generational, skeletal, and substitutional diversities in generation one poly(amidoamine) dendrimers
    • Shia, X.; Bányaib, I.; Islama, M. T.; Lesniaka, W.; Davisa, D. Z.; Baker, J. R.; Balogh, L. P. Generational, skeletal, and substitutional diversities in generation one poly(amidoamine) dendrimers Polymer 2005, 46 (9) 3022-3034
    • (2005) Polymer , vol.46 , Issue.9 , pp. 3022-3034
    • Shia, X.1    Bányaib, I.2    Islama, M.T.3    Lesniaka, W.4    Davisa, D.Z.5    Baker, J.R.6    Balogh, L.P.7


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