Apoptosis and immuno-suppression in sheep infected with bluetongue virus serotype-23

Veterinary Microbiology

Volumn 144, Issue 3-4, 2010, Pages 310-318

  Umeshappa, Channakeshava Sokke ^a   Singh, Karam Pal ^a   Nanjundappa, Roopa Hebbandi ^b   Pandey, Awadh Bihari ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b KUVEMPU UNIVERSITY   (India)

Author keywords

Apoptosis; BTV 23; Immuno suppression; Interferon and Caspase 3; Mononuclear leukocytes

Indexed keywords

ALPHA INTERFERON; ANNEXIN; CASPASE 3; DNA; PROPIDIUM IODIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLUETONGUE; BLUETONGUE ORBIVIRUS; CONTROLLED STUDY; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE DEPLETION; MONONUCLEAR CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PASTEURELLA; PNEUMONIA; SPLEEN CELL;

ANIMALS; APOPTOSIS; BLUETONGUE; BLUETONGUE VIRUS; CASPASE 3; GENE EXPRESSION REGULATION; IMMUNOSUPPRESSION; LEUKOCYTES, MONONUCLEAR; LUNG; LYMPHOID TISSUE; PROTO-ONCOGENE PROTEINS C-BCL-2; SEROTYPING; SHEEP; SPLEEN; TIME FACTORS; VIREMIA;

BLUETONGUE VIRUS; BLUETONGUE VIRUS 23; OVIS ARIES; PASTEURELLA;

EID: 77955575164     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2010.02.033     Document Type: Article

References (57)

1. Ayala A., Meldrum D.R., Perrin M.M., Chaudry I.H. The release of transforming growth factor-beta following haemorrhage: its role as a mediator of host immunosuppression. Immunology 1993, 79:479-484.
2. Bahl K., Kim S.K., Calcagno C., Ghersi D., Puzone R., Celada F., Selin L.K., Welsh R.M. IFN-induced attrition of CD8 T cells in the presence or absence of cognate antigen during the early stages of viral infections. J. Immunol. 2006, 176:4284-4295.
3. Barratt-Boyes S.M., MacLachlan N.J. Pathogenesis of bluetongue virus infection of cattle. J. Am. Vet. Med. Assoc. 1995, 206:1322-1329.
4. Barratt-Boyes S.M., Rossitto P.V., Stott J.L., MacLachlan N.J. Flow cytometric analysis of in vitro bluetongue virus infection of bovine blood mononuclear cells. J. Gen. Virol. 1992, 73(Pt 8):1953-1960.
5. Benjamin M.M. Outline of Veterinary Clinical Pathology 2001, Kalyani publishers, New Delhi. 3rd ed.
6. Brincks E.L., Kucaba T.A., Legge K.L., Griffith T.S. Influenza-induced expression of functional tumor necrosis factor-related apoptosis-inducing ligand on human peripheral blood mononuclear cells. Hum. Immunol. 2008, 69:634-646.
7. Brodie S.J., Wilson W.C., O'Hearn P.M., Muthui D., Diem K., Pearson L.D. The effects of pharmacological and lentivirus-induced immune suppression on orbivirus pathogenesis: assessment of virus burden in blood monocytes and tissues by reverse transcription-in situ PCR. J. Virol. 1998, 72:5599-5609.
8. Calvo-Pinilla E., Rodriguez-Calvo T., Anguita J., Sevilla N., Ortego J. Establishment of a bluetongue virus infection model in mice that are deficient in the alpha/beta interferon receptor. PLoS One 2009, 4:e5171.
9. Calvo-Pinilla E., Rodriguez-Calvo T., Sevilla N., Ortego J. Heterologous prime boost vaccination with DNA and recombinant modified vaccinia virus Ankara protects IFNAR(-/-) mice against lethal bluetongue infection. Vaccine 2009, 28:437-445.
10. Culling C.F.A. Handbook of Histopathological Technique 1957, Butterworth and Co., Ltd., London.
11. DeMaula C.D., Jutila M.A., Wilson D.W., MacLachlan N.J. Infection kinetics, prostacyclin release and cytokine-mediated modulation of the mechanism of cell death during bluetongue virus infection of cultured ovine and bovine pulmonary artery and lung microvascular endothelial cells. J. Gen. Virol. 2001, 82:787-794.
12. DeMaula C.D., Leutenegger C.M., Bonneau K.R., MacLachlan N.J. The role of endothelial cell-derived inflammatory and vasoactive mediators in the pathogenesis of bluetongue. Virology 2002, 296:330-337.
13. DeMaula C.D., Leutenegger C.M., Jutila M.A., MacLachlan N.J. Bluetongue virus-induced activation of primary bovine lung microvascular endothelial cells. Vet. Immunol. Immunopathol. 2002, 86:147-157.
14. Dzik W.H. Apoptosis, TGF beta and transfusion-related immunosuppression: biologic versus clinical effects. Transfus. Apher. Sci. 2003, 29:127-129.
15. Ellis J.A., Luedke A.J., Davis W.C., Wechsler S.J., Mecham J.O., Pratt D.L., Elliott J.D. T lymphocyte subset alterations following bluetongue virus infection in sheep and cattle. Vet. Immunol. Immunopathol. 1990, 24:49-67.
16. Fanger N.A., Maliszewski C.R., Schooley K., Griffith T.S. Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). J. Exp. Med. 1999, 190:1155-1164.
17. Foster N.M., Luedke A.J., Parsonson I.M., Walton T.E. Temporal relationships of viremia, interferon activity, and antibody responses of sheep infected with several bluetongue virus strains. Am. J. Vet. Res. 1991, 52:192-196.
18. Ghalib H.W., Schore C.E., Osburn B.I. Immune response of sheep to bluetongue virus: in vitro induced lymphocyte blastogenesis. Vet. Immunol. Immunopathol. 1985, 10:177-188.
19. Han K.J., Su X., Xu L.G., Bin L.H., Zhang J., Shu H.B. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. J. Biol. Chem. 2004, 279:15652-15661.
20. Hemati B., Contreras V., Urien C., Bonneau M., Takamatsu H.H., Mertens P.P., Breard E., Sailleau C., Zientara S., Schwartz-Cornil I. Bluetongue virus targets conventional dendritic cells in skin lymph. J. Virol. 2009, 83:8789-8799.
21. Hengartner M.O. The biochemistry of apoptosis. Nature 2000, 407:770-776.
22. Huot A.E., Moore A.L., Roberts J.D., Hacker M.P. Nitric oxide modulates lymphocyte proliferation but not secretion of IL-2. Immunol. Invest. 1993, 22:319-327.
23. Jameson P., Schoenherr C.K., Grossberg S.E. Bluetongue virus, an exceptionally potent interferon inducer in mice. Infect. Immun. 1978, 20:321-323.
24. Jamin A., Gorin S., Cariolet R., Le Potier M.F., Kuntz-Simon G. Classical swine fever virus induces activation of plasmacytoid and conventional dendritic cells in tonsil, blood, and spleen of infected pigs. Vet. Res. 2008, 39:7.
25. Jeggo M.H., Wardley R.C., Brownlie J. The Importance of Ovine Cytotoxic T cells in Protection Against Bluetongue Virus Infection 1985, Alan R. Liss, New York, NY, pp. 477-488.
26. Jiang J., Lau L.L., Shen H. Selective depletion of nonspecific T cells during the early stage of immune responses to infection. J. Immunol. 2003, 171:4352-4358.
27. Lacetera N., Ronchi B. Evaluation of antibody response and nonspecific lymphocyte blastogenesis following inoculation of a live attenuated bluetongue virus vaccine in goats. Am. J. Vet. Res. 2004, 65:1331-1334.
28. Luedke A.J., Bowne J.G., Jochim M.M., Doyle C. Clinical and pathologic features of bluetongue in sheep. Am. J. Vet. Res. 1964, 25:963-970.
29. Maclachlan N.J., Drew C.P., Darpel K.E., Worwa G. The pathology and pathogenesis of bluetongue. J. Comp. Pathol. 2009, 141:1-16.
30. MacLachlan N.J., Thompson J. Bluetongue virus-induced interferon in cattle. Am. J. Vet. Res. 1985, 46:1238-1241.
31. Mattner J., Schindler H., Diefenbach A., Rollinghoff M., Gresser I., Bogdan C. Regulation of type 2 nitric oxide synthase by type 1 interferons in macrophages infected with Leishmania major. Eur. J. Immunol. 2000, 30:2257-2267.
32. McNally J.M., Zarozinski C.C., Lin M.Y., Brehm M.A., Chen H.D., Welsh R.M. Attrition of bystander CD8 T cells during virus-induced T-cell and interferon responses. J. Virol. 2001, 75:5965-5976.
33. Merchant I.A., Packer R.A. Veterinary Bacteriology and Virology 1983, CBS Publishers & Distributors, Delhi, India, pp. 211-222. 7th ed.
34. Mortola E., Larsen A. Bluetongue virus infection: signaling pathway activated during apoptosis. Rev. Argent. Microbiol. 2009, 41:134-140.
35. Mortola E., Noad R., Roy P. Bluetongue virus outer capsid proteins are sufficient to trigger apoptosis in mammalian cells. J. Virol. 2004, 78:2875-2883.
36. Nagaleekar V.K., Tiwari A.K., Kataria R.S., Bais M.V., Ravindra P.V., Kumar S. Bluetongue virus induces apoptosis in cultured mammalian cells by both caspase-dependent extrinsic and intrinsic apoptotic pathways. Arch. Virol. 2007, 152:1751-1756.
37. Odeon A.C., Schore C.E., Osburn B.I. The role of cell-mediated immunity in the pathogenesis of bluetongue virus serotype 11 in the experimental infection of vaccine/sensitized calves. Comp. Immunol. Microbiol. Infect. Dis. 1997, 20:219-231.
38. Owens R.J., Limn C., Roy P. Role of an arbovirus nonstructural protein in cellular pathogenesis and virus release. J. Virol. 2004, 78:6649-6656.
39. Pernthaner A., Cole S.A., Morrison L., Hein W.R. Increased expression of interleukin-5 (IL-5) IL-13, and tumor necrosis factor alpha genes in intestinal lymph cells of sheep selected for enhanced resistance to nematodes during infection with Trichostrongylus colubriformis. Infect. Immun. 2005, 73:2175-2183.
40. Quist C.F., Howerth E.W., Bounous D.I., Stallknecht D.E. Cell-mediated immune response and IL-2 production in white-tailed deer experimentally infected with hemorrhagic disease viruses. Vet. Immunol. Immunopathol. 1997, 56:283-297.
41. Quist C.F., Howerth E.W., Stallknecht D.E., Brown J., Pisell T., Nettles V.F. Host defense responses associated with experimental hemorrhagic disease in white-tailed deer. J. Wildl. Dis. 1997, 33:584-599.
42. Rasschaert J., Ladriere L., Urbain M., Dogusan Z., Katabua B., Sato S., Akira S., Gysemans C., Mathieu C., Eizirik D.L. Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells. J. Biol. Chem. 2005, 280:33984-33991.
43. Reed L.J., Muench H. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 1938, 27:493-497.
44. Rinaldo C.R., Overall J.C., Glasgow L.A. Viral replication and interferon production in fetal and adult ovine leukocytes and spleen cells. Infect. Immun. 1975, 12:1070-1077.
45. Roy P. Orbiviruses and their replication 2001, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 1835-1869. 4th ed.
46. Russell H., O'Toole D.T., Bardsley K., Davis W.C., Ellis J.A. Comparative effects of bluetongue virus infection of ovine and bovine endothelial cells. Vet. Pathol. 1996, 33:319-331.
47. Saeki K., Yuo A., Kato M., Miyazono K., Yazaki Y., Takaku F. Cell density-dependent apoptosis in HL-60 cells, which is mediated by an unknown soluble factor, is inhibited by transforming growth factor beta1 and overexpression of Bcl-2. J. Biol. Chem. 1997, 272:20003-20010.
48. Sato A., Iizuka M., Nakagomi O., Suzuki M., Horie Y., Konno S., Hirasawa F., Sasaki K., Shindo K., Watanabe S. Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells. J. Gastroenterol. Hepatol. 2006, 21:521-530.
49. Schwartz-Cornil I., Mertens P.P., Contreras V., Hemati B., Pascale F., Breard E., Mellor P.S., MacLachlan N.J., Zientara S. Bluetongue virus: virology, pathogenesis and immunity. Vet. Res. 2008, 39:46.
50. Stott J.L., Anderson G.A., Jochim M.M., Osburn B.I. Clinical expression of bluetongue disease in cattle. Proc. Annu. Meet. U.S. 1982, 126-131.
51. Stott J.L., Barber T.L., Osburn B.I. Immunologic response of sheep to inactivated and virulent bluetongue virus. Am. J. Vet. Res. 1985, 46:1043-1049.
52. Summerfield A., Alves M., Ruggli N., de Bruin M.G., McCullough K.C. High IFN-alpha responses associated with depletion of lymphocytes and natural IFN-producing cells during classical swine fever. J. Interferon. Cytokine Res. 2006, 26:248-255.
53. Takaoka A., Hayakawa S., Yanai H., Stoiber D., Negishi H., Kikuchi H., Sasaki S., Imai K., Shibue T., Honda K., Taniguchi T. Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 2003, 424:516-523.
54. Theofilopoulos A.N., Baccala R., Beutler B., Kono D.H. Type I interferons (alpha/beta) in immunity and autoimmunity. Annu. Rev. Immunol. 2005, 23:307-336.
55. Umeshappa C.S., Singh K.P., Pandey A.B., Singh R.P., Nanjundappa R.H. Cell-mediated immune response and cross-protective efficacy of binary ethylenimine-inactivated bluetongue virus serotype-1 vaccine in sheep. Vaccine. 2010, 28:2522-2531.
56. Veronesi E., Hamblin C., Mellor P.S. Live attenuated bluetongue vaccine viruses in Dorset Poll sheep, before and after passage in vector midges (Diptera: Ceratopogonidae). Vaccine 2005, 23:5509-5516.
57. Whetter L.E., Maclachlan N.J., Gebhard D.H., Heidner H.W., Moore P.F. Bluetongue virus infection of bovine monocytes. J. Gen. Virol. 1989, 70(Pt 7):1663-1676.