Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers

European Journal of Clinical Pharmacology

Volumn 66, Issue 7, 2010, Pages 721-725

  Kim, Kyoung Ah ^a   Park, Ji Young ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

Drug interaction; Fexofenadine; Metronidazole; P glycoprotein

Indexed keywords

FEXOFENADINE; GLYCOPROTEIN P; METRONIDAZOLE; PLACEBO; MULTIDRUG RESISTANCE PROTEIN; TERFENADINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG EFFICACY; DRUG HALF LIFE; DRUG POTENTIATION; EVENING DOSAGE; HUMAN; HUMAN EXPERIMENT; MALE; MORNING DOSAGE; NORMAL HUMAN; OPEN STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; VOLUNTEER; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; DRUG INTERACTION;

ADULT; DRUG INTERACTIONS; HUMANS; MALE; METRONIDAZOLE; P-GLYCOPROTEIN; TERFENADINE;

EID: 77955565855     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-010-0797-2     Document Type: Article

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