The immune response of foals to natural infection with equid herpesvirus-2 and its association with febrile illness

Veterinary Immunology and Immunopathology

Volumn 137, Issue 1-2, 2010, Pages 136-141

  Brault, Stephanie A ^a   Blanchard, Myra T ^a   Gardner, Ian A ^b   Stott, Jeffrey L ^a   Pusterla, Nicola ^b   Mapes, Samantha M ^b   Vernau, William ^a   DeJong, Keith D ^a   MacLachlan, N James ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Equid herpesvirus 2; Flow cytometry; PCR

Indexed keywords

CYTOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CELL COUNT; BLOOD SMEAR; CELLULAR IMMUNITY; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; EQUINE HERPES VIRUS; FEMALE; FEVER; FOAL; GENE EXPRESSION; HERPES SIMPLEX; IMMUNE RESPONSE; LYMPHOCYTE STRUCTURE; LYMPHOCYTOSIS; MALE; NONHUMAN; NOSE SMEAR; ONTOGENY; PERIPHERAL BLOOD MONONUCLEAR CELL; VIRUS LOAD;

EQUID HERPESVIRUS 2; EQUIDAE; HUMAN HERPESVIRUS 4;

EID: 77955560547     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2010.05.010     Document Type: Article

References (20)

1. Allen G.P., Murray M.J. Equid herpesvirus 2 and equid herpesvirus 5 infections. Infectious Diseases of Livestock 2004, 860-867. Oxford University Press, Oxford. J.A.W. Coetzer, R.C. Tustin (Eds.).
2. Balfour H.H., Holman C.J., Hokanson K.M., Lelonek M.M., Giesbrecht J.E., White D.R., Schmeling D.O., Webb C.H., Cavert W., Wang D.H., Brundage R.C. A prospective clinical study of Epstein-Barr virus and host interactions during acute infectious mononucleosis. J. Infect. Dis. 2005, 192:1505-1512.
3. Breathnach C.C., Sturgill-Wright T., Stiltner J.L., Adams A.A., Lunn D.P., Horohov D.W. Foals are interferon gamma-deficient at birth. Vet. Immunol. Immunopathol. 2006, 112:199-209.
4. Browning G.F., Studdert M.J. Equine herpesvirus 2 (equine cytomegalovirus). Vet. Bull. 1988, 58:775-790.
5. Collinson P.N., O'Rielly J.L., Ficorilli N., Studdert M.J. Isolation of equine herpesvirus type 2 (equine gammaherpesvirus 2) from foals with keratoconjunctivitis. J. Am. Vet. Med. Assoc. 1994, 205:329-331.
6. Corsi M.M., Ruscica M., Passoni D., Scarmozzino M.G., Gulletta E. High Th1-type cytokine serum levels in patients with infectious mononucleosis. Acta Virol. 2004, 48:263-266.
7. Dunowska M., Wilks C.R., Studdert M., Meers J. Viruses associated with outbreaks of equine respiratory disease in New Zealand. New Zeal. Vet. J. 2002, 50:132-139.
8. Evans A.S. Infectious mononucleosis and related syndromes. Am. J. Med. Sci. 1978, 276:325-339.
9. Kemeny L., Pearson J.E. Isolation of herpesvirus from equine leukocytes: comparison with equine rhinopneumonitis virus. Can. J. Comp. Med. 1970, 34:59-65.
10. Kershaw O., von Oppen T., Glitz F., Deegen E., Ludwig H., Borchers K. Detection of equine herpesvirus type 2 (EHV-2) in horses with keratoconjunctivitis. Virus Res. 2001, 80:93-99.
11. Martina B.E., Verjans G.M., Kuiken T., van Amerongen G., Osterhaus A.D. In vitro and in vivo replication of seal gammaherpesviruses in cells of multiple species. Microbes Infect. 2007, 9:40-46.
12. Pusterla N., Magdesian K.G., Mapes S., Leutenegger C.M. Expression of molecular markers in blood of neonatal foals with sepsis. Am. J. Vet. Res. 2006, 67:1045-1049.
13. Pusterla N., Wilson W.D., Conrad P.A., Barr B.C., Ferraro G.L., Daft B.M., Leutenegger C.M. Cytokine gene signatures in neural tissue of horses with equine protozoal myeloencephalitis or equine herpes type 1 myeloencephalopathy. Vet. Rec. 2006, 159:341-346.
14. Pusterla N., Wilson W.D., Conrad P.A., Mapes S., Leutenegger C.M. Comparative analysis of cytokine gene expression in cerebrospinal fluid of horses without neurologic signs or with selected neurologic disorders. Am. J. Vet. Res. 2006, 67:1433-1437.
15. Reed L.J., Muench H. A simple method of estimating 50 percent end points. Am. J. Hyg. 1938, 27:493-497.
16. Roeder P.L., Scott G.R. The prevalence of equid herpes virus 2 infections. Vet. Rec. 1975, 96:404-405.
17. Silins S.L., Sherritt M.A., Silleri J.M., Cross S.M., Elliott S.L., Bharadwaj M., Le T.T., Morrison L.E., Khanna R., Moss D.J., Suhrbier A., Misko I.S. Asymptomatic primary Epstein-Barr virus infection occurs in the absence of blood T-cell repertoire perturbations despite high levels of systemic viral load. Blood 2001, 98:3739-3744.
18. Simon M.W. The atypical lymphocyte. Int. Pediatr. 2003, 18:20-22.
19. Sitki-Green D.L., Edwards R.H., Covington M.M., Raab-Traub N. Biology of Epstein-Barr virus during infectious mononucleosis. J. Infect. Dis. 2004, 189:483-492.
20. Takasugi M. An improved flurochromatic cytotoxic test. Transplant 1971, 12:148-151.