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European Journal of Medicinal Chemistry

Volumn 45, Issue 9, 2010, Pages 4140-4148

Synthesis and biological evaluation of cyclic nitrogen mustards based on carnitine framework

(4) Leiris, Simon a Lucas, Marc a Dupuy D'Angeac, Arnaud a Morre, Alain a

a UNIVERSITÉ DE MONTPELLIER (France)

Author keywords

Cyclic nitrogen mustard; l Carnitine; Mitochondria

Indexed keywords

2 ACETYLOXY 3 [N,N BIS(2 CHLOROETHYL)AMINO]CYCLO HEXANECARBOXYLIC ACID; 2 CAPRYLOYLOXY 3 [N,N BIS(2 CHLOROETHYL)AMINO]CYCLO HEXANECARBOXYLIC ACID; 2 HYDROXY 3 [N,N BIS(2 CHLOROETHYL)AMINO]CYCLO HEXANECARBOXYLIC ACID; 2 PALMITOYLOXY 3 [N,N BIS(2 CHLOROETHYL)AMINO]CYCLO HEXANECARBOXYLIC ACID; CARNITINE; CHLORAMBUCIL; CHLORMETHINE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CYTOTOXICITY; HUMAN; HUMAN CELL; LIPOPHILICITY; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CARNITINE; HUMANS; INHIBITORY CONCENTRATION 50; MITOCHONDRIA; NITROGEN MUSTARD COMPOUNDS;

EID: 77955551799 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.06.003 Document Type: Article

Times cited : (10)

References (33)

1
- 0001676690
- S.R. Rajski, and R.M. Williams Chem. Rev. 98 1998 2723 2796
- (1998) Chem. Rev. , vol.98 , pp. 2723-2796
- Rajski, S.R.¹ Williams, R.M.²

2
- 0028802866
- S.M. Rink, and P.B. Hopkins Bioorg. Med. Chem. Lett. 5 1995 2845 2850
- (1995) Bioorg. Med. Chem. Lett. , vol.5 , pp. 2845-2850
- Rink, S.M.¹ Hopkins, P.B.²

3
- 0029145803
- C.J. Springer, and I. Niculescu-Duvaz Anti-Cancer Drug Des 10 1995 361 372
- (1995) Anti-Cancer Drug des , vol.10 , pp. 361-372
- Springer, C.J.¹ Niculescu-Duvaz, I.²

4
- 0033769918
- I. Higuchi, T. Niiyama, Y. Uchida, M. Inose, J. Hu, M. Nakagawa, K. Arimura, and M. Osame Acta Neuropathol. 100 2000 718 722
- (2000) Acta Neuropathol. , vol.100 , pp. 718-722
- Higuchi, I.¹ Niiyama, T.² Uchida, Y.³ Inose, M.⁴ Hu, J.⁵ Nakagawa, M.⁶ Arimura, K.⁷ Osame, M.⁸

5
- 0033937840
- P.D. Lewis, P.W. Baxter, A.P. Griffiths, J.M. Parry, and D.O.F. Skibinski J. Pathol. 191 2000 274 281
- (2000) J. Pathol. , vol.191 , pp. 274-281
- Lewis, P.D.¹ Baxter, P.W.² Griffiths, A.P.³ Parry, J.M.⁴ Skibinski, D.O.F.⁵

6
- 0032978456
- N. Tatsuta, N. Susuki, T. Mochizuki, K. Koya, M. Kawakami, T. Shishido, N. Motoji, H. Kuroiwa, A. Shigematsu, and L.B. Chen Cancer Chemoth. Pharm. 43 1999 295 301
- (1999) Cancer Chemoth. Pharm. , vol.43 , pp. 295-301
- Tatsuta, N.¹ Susuki, N.² Mochizuki, T.³ Koya, K.⁴ Kawakami, M.⁵ Shishido, T.⁶ Motoji, N.⁷ Kuroiwa, H.⁸ Shigematsu, A.⁹ Chen, L.B.¹⁰

7
- 0034608786
- P. Constantini, E. Jacotot, D. Decaudin, and G. Kroemer J. Natl. Cancer Inst. 92 2000 1042 1053
- (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1042-1053
- Constantini, P.¹ Jacotot, E.² Decaudin, D.³ Kroemer, G.⁴

8
- 0031974274
- D. Decaudin, I. Marzo, C. Brenner, and G. Kroemer Int. J. Oncol. 12 1998 141 152
- (1998) Int. J. Oncol. , vol.12 , pp. 141-152
- Decaudin, D.¹ Marzo, I.² Brenner, C.³ Kroemer, G.⁴

9
- 0030664094
- A. Dorward, S. Sweet, R. Moorehead, and G. Singh J. Bioenerg. Biomembr. 29 1997 385 392
- (1997) J. Bioenerg. Biomembr. , vol.29 , pp. 385-392
- Dorward, A.¹ Sweet, S.² Moorehead, R.³ Singh, G.⁴

10
- 0034937266
- J.M. Grad, E. Cepero, and L.H. Boise Drug Resist. Updat. 4 2001 85 91
- (2001) Drug Resist. Updat. , vol.4 , pp. 85-91
- Grad, J.M.¹ Cepero, E.² Boise, L.H.³

11
- 0037294469
- L. Faissat, K. Martin, C. Chavis, J.L. Montéro, and M. Lucas Bioorg. Med. Chem. 11 2003 325 334
- (2003) Bioorg. Med. Chem. , vol.11 , pp. 325-334
- Faissat, L.¹ Martin, K.² Chavis, C.³ Montéro, J.L.⁴ Lucas, M.⁵

12
- 0028147066
- W.J. Brouillette, A. Saeed, A. Abuelyaman, T.L. Hutchison, P.E. Wolkowicz, and J.B. McMillin J. Org. Chem. 59 1994 4297 4303
- (1994) J. Org. Chem. , vol.59 , pp. 4297-4303
- Brouillette, W.J.¹ Saeed, A.² Abuelyaman, A.³ Hutchison, T.L.⁴ Wolkowicz, P.E.⁵ McMillin, J.B.⁶

13
- 0032811374
- T.L. Hutchison, A. Saeed, P.E. Wolkowicz, J.B. McMillin, and W.J. Brouillette Bioorg. Med. Chem. 7 1999 1505 1511
- (1999) Bioorg. Med. Chem. , vol.7 , pp. 1505-1511
- Hutchison, T.L.¹ Saeed, A.² Wolkowicz, P.E.³ McMillin, J.B.⁴ Brouillette, W.J.⁵

14
- 37049092996
- S.G. Davies, and G.H. Whitham J. Chem. Soc. Perkin Trans. 1 1976 2279 2280
- (1976) J. Chem. Soc. Perkin Trans. , vol.1 , pp. 2279-2280
- Davies, S.G.¹ Whitham, G.H.²

15
- 37049095996
- S.G. Davies, and G.H. Whitham J. Chem. Soc. Perkin Trans. 1 1977 572 575
- (1977) J. Chem. Soc. Perkin Trans. , vol.1 , pp. 572-575
- Davies, S.G.¹ Whitham, G.H.²

16
- 0030597092
- J. Augé, and F. Leroy Tetrahedron Lett. 37 1996 7715 7716
- (1996) Tetrahedron Lett. , vol.37 , pp. 7715-7716
- Augé, J.¹ Leroy, F.²

17
- 0033518579
- D.H. Qin, H.S. Byun, and R. Bittman J. Am. Chem. Soc. 121 1999 662 668
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 662-668
- Qin, D.H.¹ Byun, H.S.² Bittman, R.³

18
- 0021364567
- K.M. Chen, and M.M. Joullié Tetrahedron Lett. 25 1984 393 394
- (1984) Tetrahedron Lett. , vol.25 , pp. 393-394
- Chen, K.M.¹ Joullié, M.M.²

19
- 0002653709
- C.K. Hwang, W.S. Li, and K.C. Nicolaou Tetrahedron Lett. 25 1984 2295 2296
- (1984) Tetrahedron Lett. , vol.25 , pp. 2295-2296
- Hwang, C.K.¹ Li, W.S.² Nicolaou, K.C.³

20
- 0033516520
- S. Delagrange, and F. Nepveu Tetrahedron Lett. 40 1999 4989 4992
- (1999) Tetrahedron Lett. , vol.40 , pp. 4989-4992
- Delagrange, S.¹ Nepveu, F.²

21
- 0027932977
- F. Matsuura, Y. Hamada, and T. Shioiri Tetrahedron 50 1994 9457 9470
- (1994) Tetrahedron , vol.50 , pp. 9457-9470
- Matsuura, F.¹ Hamada, Y.² Shioiri, T.³

22
- 0028122014
- C.J. Springer, I. Niculescu-Duvaz, and R.B. Pedley J. Med. Chem. 37 1994 2361 3370
- (1994) J. Med. Chem. , vol.37 , pp. 2361-3370
- Springer, C.J.¹ Niculescu-Duvaz, I.² Pedley, R.B.³

23
- 0028322136
- E.N. Chauvel, P. Coric, C. Llorens-Corts, S. Wilk, B.P. Roques, and M.C. Fournié-Zaluski J. Med. Chem. 37 1994 1339 1346
- (1994) J. Med. Chem. , vol.37 , pp. 1339-1346
- Chauvel, E.N.¹ Coric, P.² Llorens-Corts, C.³ Wilk, S.⁴ Roques, B.P.⁵ Fournié-Zaluski, M.C.⁶

24
- 0027385182
- C.H. Kuo, S.P. Plevyak, T. Biftu, W.H. Parsons, and G.D. Berger Tetrahedron Lett. 34 1993 6863 6866
- (1993) Tetrahedron Lett. , vol.34 , pp. 6863-6866
- Kuo, C.H.¹ Plevyak, S.P.² Biftu, T.³ Parsons, W.H.⁴ Berger, G.D.⁵

25
- 0031576823
- E.C. Taylor, and J.E. Dowling Bioorg. Med. Chem. Lett. 7 1997 453 456
- (1997) Bioorg. Med. Chem. Lett. , vol.7 , pp. 453-456
- Taylor, E.C.¹ Dowling, J.E.²

26
- 0014061273
- G. Swift, and D. Swern J. Org. Chem. 32 1967 511 517
- (1967) J. Org. Chem. , vol.32 , pp. 511-517
- Swift, G.¹ Swern, D.²

27
- 14844303676
- L.L. Parker, F.M. Anderson, C.C. O'Hare, S.M. Lacy, J.P. Bingham, D.J. Robins, and J.A. Hartley Bioorg. Med. Chem. 13 2005 2389 2395
- (2005) Bioorg. Med. Chem. , vol.13 , pp. 2389-2395
- Parker, L.L.¹ Anderson, F.M.² O'Hare, C.C.³ Lacy, S.M.⁴ Bingham, J.P.⁵ Robins, D.J.⁶ Hartley, J.A.⁷

28
- 0008376151
- G.V. Rao, and C.C. Price J. Org. Chem. 27 1962 205 210
- (1962) J. Org. Chem. , vol.27 , pp. 205-210
- Rao, G.V.¹ Price, C.C.²

29
- 18244393748
- C.M. Rink, M.C. Mauck, I. Asif, M.E. Pitzer, and E.E. Fenlon Org. Lett. 7 2005 1165 1168
- (2005) Org. Lett. , vol.7 , pp. 1165-1168
- Rink, C.M.¹ Mauck, M.C.² Asif, I.³ Pitzer, M.E.⁴ Fenlon, E.E.⁵

30
- 0029621825
- C.J. Springer, R. Dowell, P.J. Burke, E. Hadley, D.H. Davies, D.C. Blakey, R.G. Melton, and I. Niculescu-Duvaz J. Med. Chem. 38 1995 5051 5065
- (1995) J. Med. Chem. , vol.38 , pp. 5051-5065
- Springer, C.J.¹ Dowell, R.² Burke, P.J.³ Hadley, E.⁴ Davies, D.H.⁵ Blakey, D.C.⁶ Melton, R.G.⁷ Niculescu-Duvaz, I.⁸

31
- 24044553274
- M. Togrul, M. Askin, and H. Hosgoren Tetrahedron-Asymmetr 16 2005 2771 2777
- (2005) Tetrahedron-Asymmetr , vol.16 , pp. 2771-2777
- Togrul, M.¹ Askin, M.² Hosgoren, H.³

32
- 0029087804
- G.J. Xie, R. Gupta, and J.W. Lown Anti-Cancer Drug Des 10 1995 389 409
- (1995) Anti-Cancer Drug des , vol.10 , pp. 389-409
- Xie, G.J.¹ Gupta, R.² Lown, J.W.³

33
- 0027440220
- W.J. Brouillette, S.W. Puckett, R.N. Comber, and C.A. Hosmer Biochem. Pharmacol. 46 1993 1671 1673
- (1993) Biochem. Pharmacol. , vol.46 , pp. 1671-1673
- Brouillette, W.J.¹ Puckett, S.W.² Comber, R.N.³ Hosmer, C.A.⁴

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