Using a pharmacokinetic model to relate an individual's susceptibility to alcohol dependence to genotypes

Human Heredity

Volumn 70, Issue 3, 2010, Pages 177-193

  Mustavich, Laura F ^a   Miller, Perry ^a   Kidd, Kenneth K ^a   Zhao, Hongyu ^a,b  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol dependence; Gene gene interactions; Genetic association; Mechanistic model; Pharmacokinetic models

Indexed keywords

ACETALDEHYDE; ALCOHOL;

ADH1B GENE; ADH1C GENE; ADH7 GENE; ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; ALDH2 GENE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; EXCRETION; GENE; GENE FREQUENCY; GENE INTERACTION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; LOGISTIC REGRESSION ANALYSIS; LUNG EXCRETION; MATHEMATICAL MODEL; SAMPLE SIZE; TAS2R38; TAS2R38 GENE; URINARY EXCRETION;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ALCOHOL DRINKING; ALCOHOLISM; ALCOHOLS; ALDEHYDE DEHYDROGENASE; ALLELES; EPISTASIS, GENETIC; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; REGRESSION ANALYSIS;

EID: 77955522828     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000317056     Document Type: Article

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