A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells

Experimental Hematology

Volumn 38, Issue 9, 2010, Pages 819-822.e3

  Kiem, Hans Peter ^a,b,c   Ironside, Christina ^a   Beard, Brian C ^a   Trobridge, Grant D ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUPAXIN; LIM PROTEIN; RETROVIRUS VECTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 19;

ANIMAL CELL; ARTICLE; BABOON; BASE PAIRING; CELL POPULATION; CONTROLLED STUDY; CPG ISLAND; GENE AMPLIFICATION; HEMATOPOIETIC CELL; HUMAN GENOME; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROVIRUS; RETROVIRUS; VIRUS DNA CELL DNA INTERACTION;

ANIMALIA; PAPIO;

EID: 77955517122     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2010.04.014     Document Type: Article

References (15)

1. Akagi K., Suzuki T., Stephens R.M., Jenkins N.A., Copeland N.G. RTCGD: retroviral tagged cancer gene database. Nucleic Acids Res 2004, 32:D523-D527.
2. Dick J.E., Magli M.C., Huszar D., Phillips R.A., Bernstein A. Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice. Cell 1985, 42:71-79.
3. Suzuki T., Shen H., Akagi K., et al. New genes involved in cancer identified by retroviral tagging. Nat Genet 2002, 32:166-174.
4. Hematti P., Hong B.K., Ferguson C., et al. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells. PLoS Biol 2004, 2:e423.
5. Beard B.C., Dickerson D., Beebe K., et al. Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells. Mol Ther 2007, 15:1356-1365.
6. Beard B.C., Mezquita P., Morris J.C., Kiem H.P. Efficient transduction and engraftment of G-CSF-mobilized peripheral blood CD34+ cells in nonhuman primates using GALV-pseudotyped gammaretroviral vectors. Mol Ther 2006, 14:212-217.
7. Kent W.J., Sugnet C.W., Furey T.S., et al. The human genome browser at UCSC. Genome Res 2002, 12:996-1006.
8. Trobridge G.D., Beard B.C., Gooch C., et al. Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors. Blood 2008, 111:5537-5543.
9. Schaller M.D. Paxillin: a focal adhesion-associated adaptor protein. Oncogene 2001, 20:6459-6472.
10. Turner C.E. Paxillin interactions. J Cell Sci 2000, 113(Pt 23):4139-4140.
11. Lipsky B.P., Beals C.R., Staunton D.E. Leupaxin is a novel LIM domain protein that forms a complex with PYK2. J Biol Chem 1998, 273:11709-11713.
12. Liu S., Thomas S.M., Woodside D.G., et al. Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses. Nature 1999, 402:676-681.
13. Dai H., Xue Y., Pan J., et al. Two novel translocations disrupt the RUNX1 gene in acute myeloid leukemia. Cancer Genet Cytogenet 2007, 177:120-124.
14. Dai H.P., Xue Y.Q., Zhou J.W., et al. LPXN, a member of the paxillin superfamily, is fused to RUNX1 in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation. Genes Chromosomes Cancer 2009, 48:1027-1036.
15. Unoki M., Okutsu J., Nakamura Y. Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia. Int J Oncol 2003, 22:1217-1223.