Differential behaviour of normal, transformed and Fanconi's anemia lymphoblastoid cells to modeled microgravity

Journal of Biomedical Science

Volumn 17, Issue 1, 2010, Pages

  Cuccarolo, Paola ^a,b   Barbieri, Francesca ^a,c   Sancandi, Monica ^a   Viaggi, Silvia ^a,b   Degan, Paolo ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; 8 HYDROXYDEOXYGUANOSINE; 8-HYDROXY-2'-DEOXYGUANOSINE; DEOXYGUANOSINE; DRUG DERIVATIVE; GLUCOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL TRANSFORMATION; DNA DAMAGE; ENERGY METABOLISM; FANCONI ANEMIA; GLUCOSE INTAKE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOBLASTOID CELL; MICROGRAVITY; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; ANALYSIS OF VARIANCE; CELL LINE; CELL PROLIFERATION; COMPARATIVE STUDY; LYMPHOCYTE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; WEIGHTLESSNESS;

ADENOSINE TRIPHOSPHATE; ANALYSIS OF VARIANCE; APOPTOSIS; CELL LINE, TRANSFORMED; CELL PROLIFERATION; DEOXYGUANOSINE; ENERGY METABOLISM; FANCONI ANEMIA; GLUCOSE; HUMANS; JURKAT CELLS; LYMPHOCYTES; MEMBRANE POTENTIAL, MITOCHONDRIAL; POLY(ADP-RIBOSE) POLYMERASES; THIOBARBITURIC ACID REACTIVE SUBSTANCES; WEIGHTLESSNESS;

EID: 77955502513     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-17-63     Document Type: Article

References (36)

1. Exposure of human lymphocytes and lymphoblastoid cells to simulated microgravity strongly affects energy metabolism and DNA repair. P Degan M Sancandi A Zunino L Ottaggio S Viaggi F Cesarone P Pippia G Galleri A Abbondandolo, J Cell Biochem 2005 94 460 9 10.1002/jcb.20302 15534877
2. Age-dependent atrophy and microgravity travel: what do they have in common? E Wang, FASEB J 1999 13 Suppl S 167 74
3. Exposure to modeled microgravity induces metabolic idleness in malignant human MCF-7 and normal murine VSMC cells. R Coinu A Chiaviello G Galleri F Franconi E Crescenzi G Palumbo, FEBS Lett 2006 580 2465 70 10.1016/j.febslet. 2006.03.078 16638572
4. Loss of signal transduction and inhibition of lymphocyte locomotion in a ground-based model of microgravity. A Sundaresan D Risin NR Pellis, In Vitro Cell Dev Biol Anim 2002 38 118 22 10.1290/1071-2690(2002)038<0118: LOSTAI>2.0.CO;2 11928994
5. Modeled microgravity-induced protein kinase C isoform expression in human lymphocytes. A Sundaresan D Risin NR Pellis, J Appl Physiol 2004 96 2028 33 10.1152/japplphysiol.01248.2003 14966022
6. Early immune response and regulation of IL-2 receptor subunits. M Hughes-Fulford E Sugano T Schopper CF Li JB Boonyaratanakornkit A Cogoli, Cell Signal 2005 17 1111 24 10.1016/j.cellsig.2004.12.016 15993752
7. Key gravity-sensitive signaling pathways drive T cell activation. JB Boonyaratanakornkit A Cogoli CF Li T Schopper P Pippia G Galleri MA Meloni M Hughes-Fulford, FASEB J 2005 19 2020 2022 16210397
8. Gene expression alterations in activated human T-cells induced by modeled microgravity. NE Ward NR Pellis SA Risin D Risin, J Cell Biochem 2006 99 1187 202 10.1002/jcb.20988 16795038
9. Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes. R Kumari KP Singh JW Dumond Jr, J Cell Biochem 2009 107 723 31 10.1002/jcb.22171 19415677
10. Prolonged weightlessness affects promyelocytic multidrug resistance. EH Piepmeier JE Kalns KM McIntyre ML Lewis, Exp Cell Res 1997 237 410 8 10.1006/excr.1997.3813 9434637
11. cDNA microarray reveals altered cytoskeletal gene expression in space-flown leukemic T lymphocytes (Jurkat). ML Lewis LA Cubano B Zhao HK Dinh JG Pabalan EH Piepmeier PD Bowman, FASEB J 2001 15 1783 5 11481229
12. Melanoma growth and tumorigenicity in models of microgravity. M Taga K Yamauchi J Odle L Furian A Sundaresan GT Ramesh NR Pellis RJ Andrassy AD Kulkarni, Aviat Space Environ Med 2006 77 1113 6 17086762
13. Fanconi anaemia genes and susceptibility to cancer. CG Mathew, Oncogene 2006 25 5875 84 10.1038/sj.onc.1209878 16998502
14. Oxidative stress in Fanconi anemia hematopoiesis and disease progression. W Du Z Adam R Rani X Zhang Q Pang, Antioxid Redox Signal 2008 10 1909 21 10.1089/ars.2008.2129 18627348
15. Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype. G Pagano P Degan M d'Ischia FJ Kelly B Nobili FV Pallardá H Youssoufian A Zatterale, Eur J Haematol 2005 75 93 100 10.1111/j.1600-0609.2005. 00507.x 16000125 (Pubitemid 41008278)
16. Molecular pathogenesis of Fanconi anemia. N Collins GM Kupfer, Int J Hematol 2005 82 176 83 10.1532/IJH97.05108 16207587
17. Molecular pathogenesis of Fanconi anemia: recent progress. T Taniguchi AD D'Andrea, Blood 2006 107 4223 33 10.1182/blood-2005-10-4240 16493006
18. Gender- and age-related distinctions for the in vivo prooxidant state in Fanconi anaemia patients. G Pagano P Degan M d'Ischia FJ Kelly FV Pallardá A Zatterale SS Anak EE Akisik G Beneduce R Calzone E De Nicola C Dunster A Lloret P Manini B Nobili A Saviano E Vuttariello M Warnau, Carcinogenesis 2004 25 1899 909 10.1093/carcin/bgh194 15192013
19. Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia. M Bogliolo S Borghini A Abbondandolo P Degan, Mutagenesis 2002 17 25 30 10.1093/mutage/17.1.25 11752230
20. Technology and developments for the Random Positioning Machine, RPM. AG Borst JJWA Van Loon, Microgravity Sci Technol 2009 21 287 292 10.1007/s12217-008-9043-2
21. Poly(ADP-ribose) polymerase is affected early by thyroid state during liver regeneration in rats. CF Cesarone L Scarabelli I Demori S Balocco E Fugassa, Am J Physiol Gastrointest Liver Physiol 2000 279 1219 25 11093944
22. Mitochondria are selective targets for the protective effects of heat shock against oxidative injury. BS Polla S Kantengwa D François S Salvioli C Franceschi C Marsac A Cossarizza, Proc Natl Acad Sci (USA) 1996 93 6458 63 10.1073/pnas.93.13.6458 (Pubitemid 26230328)
23. A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration. G De Luca MT Russo P Degan C Tiveron A Zijno E Meccia I Ventura E Mattei Y Nakabeppu M Crescenzi R Pepponi A Pèzzola P Popoli M Bignami, PLoS Genet 2008 4 1000266 10.1371/journal.pgen.1000266 19023407
24. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. A Ramanathan C Wang SL Schreiber, Proc Natl Acad Sci (USA) 2005 102 5992 7 10.1073/pnas.0502267102 (Pubitemid 40594243)
25. Spaceflight alters microtubules and increases apoptosis in human lymphocytes (Jurkat). ML Lewis JL Reynolds LA Cubano JP Hatton BD Lawless EH Piepmeier, FASEB J 1998 12 1007 18 9707173
26. In vivo accumulation of 8-hydroxy-2'-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families. P Degan S Bonassi M De Caterina LG Korkina L Pinto F Scopacasa A Zatterale R Calzone G Pagano, Carcinogenesis 1995 16 735 41 10.1093/carcin/16.4.735 7728950
27. Space flight and oxidative stress. TP Stein, Nutrition 2002 18 867 71 10.1016/S0899-9007(02)00938-3 12361781
28. Activation of nuclear transcription factor-kappaB in mouse brain induced by a simulated microgravity environment. KC Wise SK Manna K Yamauchi V Ramesh BL Wilson RL Thomas S Sarkar AD Kulkarni NR Pellis GT Ramesh, In Vitro Cell Dev Biol Anim 2005 41 118 23 10.1290/0501006.1 16029073
29. Transcriptional analysis of normal human fibroblast responses to microgravity stress. Y Liu E Wang, Genomics Proteomics Bioinformatics 2008 6 29 41 10.1016/S1672-0229(08)60018-2 18558383
30. TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro. C Dufour A Corcione J Svahn R Haupt V Poggi AN Béka'ssy R Scimè A Pistorio V Pistoia, Blood 2003 102 2053 9 10.1182/blood-2003-01-0114 12750172
31. TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. J Li DP Sejas X Zhang Y Qiu KJ Nattamai R Rani KR Rathbun H Geiger DA Williams GC Bagby Q Pang, J Clin Invest 2007 117 3283 95 10.1172/JCI31772 17960249
32. Differential expression of TP53 associated genes in Fanconi anemia cells after mitomycin C and hydroxyurea treatment. A Martinez JM Hinz L Gámez B Molina H Acũa IM Jones S Frias MA Coleman, Mutat Res 2008 656 1 7 18647660
33. Role of Fanconi DNA repair pathway in neural stem cell homeostasis. K Sii-Felice V Barroca O Etienne L Riou F Hoffschir P Fouchet FD Boussin MA Mouthon, Cell Cycle 2008 7 1911 5 18604174
34. Resistance to apoptosis in Fanconi's anaemia. An ex vivo study in peripheral blood mononuclear cells. D Monti S Macchioni M Guido G Pagano A Zatterale R Calzone A Cossarizza E Straface W Malorni C Franceschi, FEBS Lett 1997 409 365 9 10.1016/S0014-5793(97)00550-4 9224691
35. Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia. SS Mukhopadhyay KS Leung MJ Hicks PJ Hastings H Youssoufian SE Plon, J Cell Biol 2006 175 225 35 10.1083/jcb. 200607061 17060495
36. Hydrogen peroxide: effects on DNA, chromosomes, cell cycle and apoptosis induction in Fanconi's anemia cell lines. A Zunino P Degan T Vigo A Abbondandolo, Mutagenesis 2001 16 283 8 10.1093/mutage/16.3.283 11320156