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Arthritis Research and Therapy

Volumn 12, Issue 1, 2010, Pages

'Rac'-ing upstream to treat rheumatoid arthritis

(1) Firestein, Gary S a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RAC PROTEIN; RHO FACTOR; ANTIRHEUMATIC AGENT; RAC1 PROTEIN;

CYTOKINE PRODUCTION; EDITORIAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; HUMAN; METABOLISM; NOTE; PHYSIOLOGY;

ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; HUMANS; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 77955495466 PISSN: 14786354 EISSN: 14786362 Source Type: Journal
DOI: 10.1186/ar2924 Document Type: Editorial

Times cited : (4)

References (8)

1
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- Abreu JRF, de Launay D, van Hennik PB, van Stalborgh AM, ten Klooster JP, Sanders MW, Reedquist KA, Vervoordeldonk MJ, Hordijk PL, Tak PP. A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res Ther 2010, 12:R2. 10.1186/ar2900, 20053277.
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- Abreu, J.R.F.¹ de Launay, D.² van Hennik, P.B.³ van Stalborgh, A.M.⁴ ten Klooster, J.P.⁵ Sanders, M.W.⁶ Reedquist, K.A.⁷ Vervoordeldonk, M.J.⁸ Hordijk, P.L.⁹ Tak, P.P.¹⁰

2
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- 'Go upstream, young man': lessons learned from the p38 saga
- 10.1136/ard.2009.119479, 19995751
- Hammaker D, Firestein GS. 'Go upstream, young man': lessons learned from the p38 saga. Ann Rheum Dis 2010, 69(Suppl 1):i77-i82. 10.1136/ard.2009.119479, 19995751.
- (2010) Ann Rheum Dis , vol.69 , Issue.SUPPL. 1
- Hammaker, D.¹ Firestein, G.S.²

3
- 66049086274
- Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies
- 10.1002/art.24485, 19404957
- Damjanov N, Kauffman RS, Spencer-Green GT. Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: results of two randomized, double-blind, placebo-controlled clinical studies. Arthritis Rheum 2009, 60:1232-1241. 10.1002/art.24485, 19404957.
- (2009) Arthritis Rheum , vol.60 , pp. 1232-1241
- Damjanov, N.¹ Kauffman, R.S.² Spencer-Green, G.T.³

4
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- Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial
- 10.1002/art.23992, 18975322
- Weinblatt ME, Kavanaugh A, Burgos-Vargas R, Dikranian AH, Medrano-Ramirez G, Morales-Torres JL, Murphy FT, Musser TK, Straniero N, Vicente-Gonzales AV, Grossbard E. Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial. Arthritis Rheum 2008, 58:3309-3318. 10.1002/art.23992, 18975322.
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- Weinblatt, M.E.¹ Kavanaugh, A.² Burgos-Vargas, R.³ Dikranian, A.H.⁴ Medrano-Ramirez, G.⁵ Morales-Torres, J.L.⁶ Murphy, F.T.⁷ Musser, T.K.⁸ Straniero, N.⁹ Vicente-Gonzales, A.V.¹⁰ Grossbard, E.¹¹

5
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- The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo
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- Kremer JM, Bloom BJ, Breedveld FC, Coombs JH, Fletcher MP, Gruben D, Krishnaswami S, Burgos-Vargas R, Wilkinson B, Zerbini CA, Zwillich SH. The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum 2009, 60:1895-1905. 10.1002/art.24567, 19565475.
- (2009) Arthritis Rheum , vol.60 , pp. 1895-1905
- Kremer, J.M.¹ Bloom, B.J.² Breedveld, F.C.³ Coombs, J.H.⁴ Fletcher, M.P.⁵ Gruben, D.⁶ Krishnaswami, S.⁷ Burgos-Vargas, R.⁸ Wilkinson, B.⁹ Zerbini, C.A.¹⁰ Zwillich, S.H.¹¹

6
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- Mammalian Rho GTPases: new insights into their functions from in vivo studies
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- Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 2008, 9:690-701. 10.1038/nrm2476, 18719708.
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7
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- Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis
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- Yamanishi Y, Boyle DL, Pinkoski MJ, Mahboubi A, Lin T, Han Z, Zvaifler NJ, Green DR, Firestein GS. Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis. Am J Pathol 2002, 160:123-130. 1867134, 11786406.
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- Yamanishi, Y.¹ Boyle, D.L.² Pinkoski, M.J.³ Mahboubi, A.⁴ Lin, T.⁵ Han, Z.⁶ Zvaifler, N.J.⁷ Green, D.R.⁸ Firestein, G.S.⁹

8
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- Kinetic analysis of synovial signaling and gene expression in animal models of arthritis
- Fukushima A, Boyle DL, Corr M, Firestein GS. Kinetic analysis of synovial signaling and gene expression in animal models of arthritis. Ann Rheum Dis 2009,
- (2009) Ann Rheum Dis
- Fukushima, A.¹ Boyle, D.L.² Corr, M.³ Firestein, G.S.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.