Retrocorneal membranes: A comparative immunohistochemical analysis of keratocytic, endothelial, and epithelial origins

American Journal of Ophthalmology

Volumn 150, Issue 2, 2010, Pages 230-242.e2

  Jakobiec, Frederick A ^a,b   Bhat, Pooja ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD34 ANTIBODY; CYTOKERATIN 7; EOSIN; HEMATOXYLIN; PARAFFIN; VIMENTIN; ACTIN; ALPHA SMA PROTEIN, HUMAN; ALPHA-SMA PROTEIN, HUMAN; CD34 ANTIGEN; KERATIN;

AGED; ARTICLE; COMPARATIVE STUDY; CORNEA CELL; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; DESCEMET MEMBRANE; ENDOTHELIAL KERATOPLASTY; ENDOTHELIUM CELL; ENUCLEATION; EPITHELIUM CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MEDICAL RECORD REVIEW; METAPLASIA; OBSERVATION; PENETRATING KERATOPLASTY; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCAR; STROMA; CELL MEMBRANE; CORNEA DISEASE; CORNEA STROMA; ENZYME IMMUNOASSAY; FEMALE; FIBROBLAST; METABOLISM; MIDDLE AGED; PATHOLOGY;

ACTINS; AGED; ANTIGENS, CD34; CELL MEMBRANE; CORNEAL DISEASES; CORNEAL STROMA; ENDOTHELIUM, CORNEAL; EPITHELIUM, CORNEAL; FEMALE; FIBROBLASTS; HUMANS; IMMUNOENZYME TECHNIQUES; KERATINS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; VIMENTIN;

EID: 77955494889     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2010.03.011     Document Type: Article

References (40)

1. S.E. Bloomfield, F.A. Jakobiec, and T. Iwamoto Fibrous ingrowth with retrocorneal membrane Ophthalmology 88 1981 459 465
2. T. Lifshitz, T. Oshry, and G. Rosenthal Retrocorneal membrane after penetrating keratoplasty Ophthalmic Surg Lasers 32 2001 159 161
3. R. Banik, L.H. Novick, R.E. Smith, and R.S. Chuck Retrocorneal membrane with Descemet's detachment Cornea 20 2001 763 764
4. S.E. Bloomfield, F.A. Jakobiec, T. Iwamoto, and W.G. Harrison Retrocorneal pigmentation secondary to iris stromal melanocytic proliferation Ophthalmology 88 1981 1274 1280
5. T. Kohnen, D.D. Koch, and R.L. Font Lensification of the posterior corneal surface An unusual proliferation of lens epithelial cells Ophthalmology 104 1997 1343 1347
6. N.S. Jaffe, M.S. Jaffe, and G.F. Jaffe Cataract surgery and its complications 1997 St Louis Mosby 427 480
7. E.S. Sherrard, and P.V. Rycroft Retrocorneal membranes. I Their origin and structure Br J Ophthalmol 51 1967 379 386
8. S.H. Chen, and R. Pineda 2nd Epithelial and fibrous downgrowth: mechanisms of disease Ophthalmol Clin North Am 15 2002 41 48
9. H. Obata, and T. Tsuru Corneal wound healing from the perspective of keratoplasty specimens with special reference to the function of the Bowman layer and Descemet membrane Cornea 26 2007 S82 S89
10. D.M. Albert, and J.W. Miller Principles and Practice of Ophthalmology 2008 Saunders/Elsevier Philadelphia
11. M. Yanoff, and J.S. Duker Ophthalmology 2009 Mosby/Elsevier St Louis
12. T.R. Kramer, H.E. Grossniklaus, N. Vigneswaran, G.O. Waring, and A. Kozarsky Cytokeratin expression in corneal endothelium in the iridocorneal endothelial syndrome Invest Ophthalmol Vis Sci 33 1992 3581 3585
13. G.C. Cockerham, and A.A. Hidayat Retrocorneal membrane with myofibroblasts after perforating injury: an immunohistochemical and ultrastructural study of 11 cases Cornea 18 1999 700 706
14. G.C. Cockerham, N.V. Laver, A.A. Hidayat, and D.L. McCoy An immunohistochemical analysis and comparison of posterior polymorphous dystrophy with congenital hereditary endothelial dystrophy Cornea 21 2002 787 791
15. E.M. Espana, T. Kawakita, C.Y. Liu, and S.C. Tseng CD-34 expression by cultured human keratocytes is downregulated during myofibroblast differentiation induced by TGF-beta1 Invest Ophthalmol Vis Sci 45 2004 2985 2991
16. A.A. Hidayat, and G.C. Cockerham Epithelial metaplasia of the corneal endothelium in Fuchs endothelial dystrophy Cornea 25 2006 956 959
17. K. Jirsova, S. Merjava, and R. Martincova Immunohistochemical characterization of cytokeratins in the abnormal corneal endothelium of posterior polymorphous corneal dystrophy patients Exp Eye Res 84 2007 680 686
18. S. Merjava, A. Neuwirth, V. Mandys, and K. Jirsova Cytokeratins 8 and 18 in adult human corneal endothelium Exp Eye Res 89 2009 426 431
19. D.G. Said, M. Nubile, and T. Alomar Histologic features of transplanted amniotic membrane: implications for corneal wound healing Ophthalmology 116 2009 1287 1295
20. T. Saito, K. Nishida, and H. Sugiyama Abnormal keratocytes and stromal inflammation in chronic phase of severe ocular surface diseases with stem cell deficiency Br J Ophthalmol 92 2008 404 410
21. R. Pineda, V. Jain, P. Gupta, and F.A. Jakobiec Descemet's stripping endothelial keratoplasty: an effective treatment for toxic anterior segment syndrome with histopathologic findings Cornea 29 2009 694 697
22. F.A. Jakobiec, P. Bhat, and K. Colby Immunohistochemical studies of conjunctival nevi and melanomas Arch Ophthalmol 128 2010 174 183
23. I. Moll, C. Kuhn, and R. Moll Cytokeratin 20 is a general marker of cutaneous Merkel cells while certain neuronal proteins are absent J Invest Dermatol 104 1995 910 915
24. J.H. Yeo, F.A. Jakobiec, K. Pokorny, T. Iwamoto, and A. Pisacano The ultrastructure of an IOL "cocoon membrane." Ophthalmology 90 1983 410 419
25. I.M. Neuhann, G. Kleinmann, D.J. Apple, S.K. Pandey, and T.F. Neuhann Cocooning of an iris-fixated intraocular lens in a 3-year-old child after perforating injury: clinicopathologic correlation J Cataract Refract Surg 31 2005 1826 1828
26. K.C. Swan Fibroblastic ingrowth following cataract extraction Arch Ophthalmol 89 1973 445 449
27. V.L. Weimar The sources of fibroblasts in corneal wound repair; a quantitative analysis AMA Arch Ophthalmol 60 1958 93 109
28. C.S. Brissette-Storkus, S.M. Reynolds, A.J. Lepisto, and R.L. Hendricks Identification of a novel macrophage population in the normal mouse corneal stroma Invest Ophthalmol Vis Sci 43 2002 2264 2271
29. P. Hamrah, Y. Liu, Q. Zhang, and M.R. Dana The corneal stroma is endowed with a significant number of resident dendritic cells Invest Ophthalmol Vis Sci 44 2003 581 589
30. R. Abe, S.C. Donnelly, T. Peng, R. Bucala, and C.N. Metz Peripheral blood fibrocytes: differentiation pathway and migration to wound sites J Immunol 166 2001 7556 7562
31. E.W. Leung, L. Rife, R.E. Smith, and E.P. Kay Extracellular matrix components in retrocorneal fibrous membrane in comparison to corneal endothelium and Descemet's membrane Mol Vis 6 2000 15 23
32. G. Martone, C. Tommasi, and C. Traversi Unilateral corneal endothelial dystrophy and anterior keratoconus Eur J Ophthalmol 17 2007 430 432
33. S. Merjava, P. Liskova, Y. Sado, P.F. Davis, N.S. Greenhill, and K. Jirsova Changes in the localization of collagens IV and VIII in corneas obtained from patients with posterior polymorphous corneal dystrophy Exp Eye Res 88 2009 945 952
34. N.J. Anderson, D.Y. Badawi, H.E. Grossniklaus, and R.D. Stulting Posterior polymorphous membranous dystrophy with overlapping features of iridocorneal endothelial syndrome Arch Ophthalmol 119 2001 624 625
35. S. Kawasaki, H. Tanioka, K. Yamasaki, N. Yokoi, A. Komuro, and S. Kinoshita Clusters of corneal epithelial cells reside ectopically in human conjunctival epithelium Invest Ophthalmol Vis Sci 47 2006 1359 1367
36. S. Yoshida, S. Shimmura, and T. Kawakita Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces Invest Ophthalmol Vis Sci 47 2006 4780 4786
37. S. Saika TGFbeta pathobiology in the eye Lab Invest 86 2006 106 115
38. S. Saika, O. Yamanaka, and Y. Okada TGF beta in fibroproliferative diseases in the eye Front Biosci (Schol Ed) 1 2009 376 390
39. U.V. Jurkunas, M. Bitar, and I. Rawe Colocalization of increased transforming growth factor-beta-induced protein (TGFBIp) and Clusterin in Fuchs endothelial corneal dystrophy Invest Ophthalmol Vis Sci 50 2009 1129 1136
40. K. Wunderlich, B.C. Senn, P. Reiser, M. Pech, J. Flammer, and P. Meyer Connective tissue growth factor in retrocorneal membranes and corneal scars Ophthalmologica 214 2000 341 346