Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population

Annals of the Rheumatic Diseases

Volumn 69, Issue 8, 2010, Pages 1572-1573

  Eyre, Stephen ^a   Hinks, Anne ^a   Flynn, Edward ^a   Martin, Paul ^a   Wilson, Anthony G ^b   Maxwell, James R ^b   Morgan, Ann W ^c   Emery, Paul ^c   Steer, Sophia ^d   Hocking, Lynne J ^e   Reid, David M ^e   Harrison, Pille ^f   Wordsworth, Paul ^f   Thomson, Wendy ^a   Worthington, Jane ^a   Barton, Anne ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^e UNIVERSITY OF ABERDEEN   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR REL;

DISEASE PREDISPOSITION; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; HUMAN; LETTER; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, PAIR 2; GENES, REL; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GREAT BRITAIN; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 77955460465     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2009.122887     Document Type: Letter

References (7)

1. Barton A, Worthington J. Genetic susceptibility to rheumatoid arthritis: an emerging picture. Arthritis Rheum 2009;61:1441-6.
2. Plenge RM, Seielstad M, Padyukov L, et al. TRAF1-C5 as a risk locus for rheumatoid arthritis - a genomewide study. N Engl J Med 2007;357:1199-209. (Pubitemid 47443179)
3. Gregersen PK, Amos CI, Lee AT, et al. REL, encoding a member of the NF-kappa B family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet 2009;41:820-3.
4. Thomson W, Barton A, Ke X, et al. Rheumatoid arthritis association at 6q23. Nat Genet 2007;39:1431-3.
5. Barton A, Thomson W, Ke X, et al. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet 2008;40:1156-9.
6. Purcell S, Neale B, Todd-Brown K, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007;81:559-75. (Pubitemid 47330214)
7. Campbell IK, Gerondakis S, O'Donnell K, et al. Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis. J Clin Invest 2000;105:1799-806. (Pubitemid 30421761)