-
1
-
-
0037237481
-
Breast cancer endocrine resistance: How growth factor signaling and estrogen receptor coregulators modulate response
-
Schiff R, Massarweh S, Shou J, Osborne CK. Breast cancer endocrine resistance: how growth factor signaling and estrogen receptor coregulators modulate response. Clin Cancer Res 2003;9:447-54S.
-
(2003)
Clin Cancer Res
, vol.9
-
-
Schiff, R.1
Massarweh, S.2
Shou, J.3
Osborne, C.K.4
-
2
-
-
12144255062
-
Combinations of endocrine and biological agents: Present status of therapeutic and presurgical investigations
-
Johnston SR. Combinations of endocrine and biological agents: present status of therapeutic and presurgical investigations. Clin Cancer Res 2005;11:889-99s.
-
(2005)
Clin Cancer Res
, vol.11
-
-
Johnston, S.R.1
-
3
-
-
42049121934
-
Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: Molecular mechanism and clinical implications for endocrine therapy
-
Arpino G, Wiechmann L, Osborne K, et al. Crosstalk between the estrogen receptor and the HER tyrosine kinase receptor family: molecular mechanism and clinical implications for endocrine therapy. Endocrine Rev 2008;29:217-33.
-
(2008)
Endocrine Rev
, vol.29
, pp. 217-233
-
-
Arpino, G.1
Wiechmann, L.2
Osborne, K.3
-
4
-
-
17844398046
-
Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase
-
Gutierrez MC, Detre S, Johnston S, et al. Molecular changes in tamoxifen-resistant breast cancer: relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase. J Clin Oncol 2005;23:2469-76.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2469-2476
-
-
Gutierrez, M.C.1
Detre, S.2
Johnston, S.3
-
5
-
-
46749144174
-
Mechanisms of resistance to ErbB-targeted cancer therapeutics
-
Wang Q, Greene MI. Mechanisms of resistance to ErbB-targeted cancer therapeutics. J Clin Invest 2008;118:2389-92.
-
(2008)
J Clin Invest
, vol.118
, pp. 2389-2392
-
-
Wang, Q.1
Greene, M.I.2
-
6
-
-
23444457449
-
Morphing into cancer: The role of developmental signaling pathways in brain tumor formation
-
Fogarty MP, Kessler JD, Wechsler-Reya RJ. Morphing into cancer: the role of developmental signaling pathways in brain tumor formation. J Neurobiol 2005;64:458-75.
-
(2005)
J Neurobiol
, vol.64
, pp. 458-475
-
-
Fogarty, M.P.1
Kessler, J.D.2
Wechsler-Reya, R.J.3
-
7
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn AJ, Gupta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518-24.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
-
8
-
-
55249092391
-
The genomic profile of HER2-amplified breast cancers: The influence of ER status
-
Marchio C, Natrajan R, Shiu KK, et al. The genomic profile of HER2-amplified breast cancers: the influence of ER status. J Pathol 2008; 216:399-407.
-
(2008)
J Pathol
, vol.216
, pp. 399-407
-
-
Marchio, C.1
Natrajan, R.2
Shiu, K.K.3
-
9
-
-
13544270852
-
Global gene expression analysis of estrogen receptor transcription factor cross talk in breast cancer: Identification of estrogen-induced/activator protein-1-dependent genes
-
DeNardo DG, Kim HT, Hilsenbeck S, et al. Global gene expression analysis of estrogen receptor transcription factor cross talk in breast cancer: Identification of estrogen-induced/activator protein-1-dependent genes. Mol Endocrinol 2005;19:362-78.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 362-378
-
-
DeNardo, D.G.1
Kim, H.T.2
Hilsenbeck, S.3
-
10
-
-
57749178899
-
Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways
-
Safe S, Kim K. Non-classical genomic estrogen receptor (ER)/specificity protein and ER/activating protein-1 signaling pathways. J Mol Endocrinol 2008;41:263-75.
-
(2008)
J Mol Endocrinol
, vol.41
, pp. 263-275
-
-
Safe, S.1
Kim, K.2
-
11
-
-
0035661317
-
Estrogen receptor: Current understanding of its activation and modulation
-
Osborne CK, Schiff R, Fuqua SA, et al. Estrogen receptor: current understanding of its activation and modulation. Clin Cancer Res 2001;7:4338-42s.
-
(2001)
Clin Cancer Res
, vol.7
-
-
Osborne, C.K.1
Schiff, R.2
Fuqua, S.A.3
-
12
-
-
15544379599
-
Estrogen-receptor biology: Continuing progress and therapeutic implications
-
Osborne CK, Schiff R. Estrogen-receptor biology: continuing progress and therapeutic implications. J Clin Oncol 2005;23:1616-22.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1616-1622
-
-
Osborne, C.K.1
Schiff, R.2
-
13
-
-
55549088531
-
Ets-1 upregulates HER2-induced MMP-1 expression in breast cancer cells
-
Park YH, Jung HH, Ahn JS, et al. Ets-1 upregulates HER2-induced MMP-1 expression in breast cancer cells. Biochem Biophys Res Commun 2008;377:389-94.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 389-394
-
-
Park, Y.H.1
Jung, H.H.2
Ahn, J.S.3
-
14
-
-
0036681322
-
Acceleration of invasive activity via matrix metalloproteinases by transfection of the estrogen receptor-α gene in endometrial carcinoma cells
-
Mizumoto H, Saito T, Ashihara K, et al. Acceleration of invasive activity via matrix metalloproteinases by transfection of the estrogen receptor-α gene in endometrial carcinoma cells. Int J Cancer 2002; 100:401-6.
-
(2002)
Int J Cancer
, vol.100
, pp. 401-406
-
-
Mizumoto, H.1
Saito, T.2
Ashihara, K.3
-
15
-
-
33748779541
-
Estrogen receptor α regulates matrix metalloproteinase-13 promoter activity primarily through the AP-1 transcriptional regulatory site
-
Lu T, Yamini A, Sciore P, et al. Estrogen receptor α regulates matrix metalloproteinase-13 promoter activity primarily through the AP-1 transcriptional regulatory site. Biochim Biophys Acta 2006;1762: 719-31.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 719-731
-
-
Lu, T.1
Yamini, A.2
Sciore, P.3
-
16
-
-
34247242607
-
Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
-
Zhou Y, Yau C, Gray JW, et al. Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer. BMC Cancer 2007;7:59.
-
(2007)
BMC Cancer
, vol.7
, pp. 59
-
-
Zhou, Y.1
Yau, C.2
Gray, J.W.3
-
17
-
-
0025346113
-
The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites
-
Gutman A, Wasylyk B. The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites. EMBO J 1990;9:2241-6.
-
(1990)
EMBO J
, vol.9
, pp. 2241-2246
-
-
Gutman, A.1
Wasylyk, B.2
-
18
-
-
33750521806
-
Low expression of HER2 protein in breast cancer is biologically significant
-
Tovey SM, Reeves JR, Stanton P, et al. Low expression of HER2 protein in breast cancer is biologically significant. J Pathol 2006; 210:358-62.
-
(2006)
J Pathol
, vol.210
, pp. 358-362
-
-
Tovey, S.M.1
Reeves, J.R.2
Stanton, P.3
-
19
-
-
33748087796
-
Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells
-
Zhu Y, Sullivan LL, Nair SS, et al. Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells. Cancer Res 2006;66:7991-8.
-
(2006)
Cancer Res
, vol.66
, pp. 7991-7998
-
-
Zhu, Y.1
Sullivan, L.L.2
Nair, S.S.3
-
20
-
-
57149137029
-
Crosstalk between IGF 1R and estrogen receptor signaling in breast cancer
-
Fagan DH, Yee D. Crosstalk between IGF 1R and estrogen receptor signaling in breast cancer. J Mammary Gland Biol Neoplasia 2008; 13:423-9.
-
(2008)
J Mammary Gland Biol Neoplasia
, vol.13
, pp. 423-429
-
-
Fagan, D.H.1
Yee, D.2
-
21
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (Protein Kinase B)
-
Zimmermann S, Moelling K. Phosphorylation and regulation of Raf by Akt (Protein Kinase B). Science 1999;286:1741-4.
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
-
23
-
-
33847147996
-
The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers
-
Marcom PK, Isaacs C, Harris L, et al. The combination of letrozole and trastuzumab as first or second-line biological therapy produces durable responses in a subset of HER2 positive and ER positive advanced breast cancers. Breast Cancer Res Treat 2007;102:43-9.
-
(2007)
Breast Cancer Res Treat
, vol.102
, pp. 43-49
-
-
Marcom, P.K.1
Isaacs, C.2
Harris, L.3
-
24
-
-
2142652244
-
Therapeutic targeting in the estrogen receptor hormonal pathway
-
Katzenellenbogen BS, Frasor J. Therapeutic targeting in the estrogen receptor hormonal pathway. Semin Oncol 2004;31:28-38.
-
(2004)
Semin Oncol
, vol.31
, pp. 28-38
-
-
Katzenellenbogen, B.S.1
Frasor, J.2
-
25
-
-
34548248572
-
Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
-
Green KA, Carroll JS. Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state. Nat Rev Cancer 2007;7:713-22.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 713-722
-
-
Green, K.A.1
Carroll, J.S.2
-
26
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tributions
-
Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tributions. Science 2002;295: 2387-92.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
27
-
-
0036716282
-
Strategies for MMP inhibition in cancer: Innovations for the post-trial era
-
Overall CM, Lopez-Otin C. Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat Rev Cancer 2002;2:657-72.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 657-672
-
-
Overall, C.M.1
Lopez-Otin, C.2
-
28
-
-
0038364286
-
Matrix metalloproteinase inhibitors (MMPIs): The beginning of phase I or the termination of phase III clinical trials
-
DOI 10.1023/A:1023047431869
-
Pavlaki M, Zucker S. Matrix metalloproteinase inhibitors (MMPIs): the beginning of phase I or the termination of phase III clinical trials. Cancer Metastasis Rev 2003;22:177-203. (Pubitemid 36561057)
-
(2003)
Cancer and Metastasis Reviews
, vol.22
, Issue.2-3
, pp. 177-203
-
-
Pavlaki, M.1
Zucker, S.2
-
29
-
-
0030932125
-
The AP-1 site and MMP gene regulation: What is all the fuss about?
-
Benhow U, Brinckerhoff CE. The AP-1 site and MMP gene regulation: What is all the fuss about? Matrix Biol 1997;15:519-26.
-
(1997)
Matrix Biol
, vol.15
, pp. 519-526
-
-
Benhow, U.1
Brinckerhoff, C.E.2
-
30
-
-
33846048058
-
Transcription factors control invasion: AP-1 the first among equals
-
Ozanne BW, Spence HJ, McGarry LC, et al. Transcription factors control invasion: AP-1 the first among equals. Oncogene 2007;26:1-10.
-
(2007)
Oncogene
, vol.26
, pp. 1-10
-
-
Ozanne, B.W.1
Spence, H.J.2
McGarry, L.C.3
-
31
-
-
41149110156
-
Overcoming endocrine resistance in breast cancer-are signal transduction inhibitors the answer?
-
Bedard PL, Freedman OC, Howell A, et al. Overcoming endocrine resistance in breast cancer-are signal transduction inhibitors the answer? Breast Cancer Res Treat 2008;108:307-17.
-
(2008)
Breast Cancer Res Treat
, vol.108
, pp. 307-317
-
-
Bedard, P.L.1
Freedman, O.C.2
Howell, A.3
-
32
-
-
2542620761
-
Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor α in breast cancer cells
-
Yang Z, Barnes CJ, Kumar R. Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor α in breast cancer cells. Clin Cancer Res 2004;10: 3621-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3621-3628
-
-
Yang, Z.1
Barnes, C.J.2
Kumar, R.3
-
33
-
-
0037303695
-
Bone markers in the management of patients with skeletal metastases
-
Demers LM. Bone markers in the management of patients with skeletal metastases. Cancer 2003;97:874-9.
-
(2003)
Cancer
, vol.97
, pp. 874-879
-
-
Demers, L.M.1
-
34
-
-
56649088162
-
MMP-1 (collagenase-1) and MMP-13 (collagenase-3) differentially regulate markers of osteoblastic differentiation in osteogenic cells
-
Hayami T, Kapila YL, Kapila S. MMP-1 (collagenase-1) and MMP-13 (collagenase-3) differentially regulate markers of osteoblastic differentiation in osteogenic cells. Matrix Biol 2008;27:682-92.
-
(2008)
Matrix Biol
, vol.27
, pp. 682-692
-
-
Hayami, T.1
Kapila, Y.L.2
Kapila, S.3
-
35
-
-
50849134800
-
Matrix metalloproteinase expression and outcome in patients with breast cancer: Analysis of a published database
-
McGowan PM, Duffy MJ. Matrix metalloproteinase expression and outcome in patients with breast cancer: analysis of a published database. Ann Oncol 2008;19:1566-72.
-
(2008)
Ann Oncol
, vol.19
, pp. 1566-1572
-
-
McGowan, P.M.1
Duffy, M.J.2
-
36
-
-
67649421573
-
Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model
-
Eck SM, Hoopes PJ, Petrella BL, et al. Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model. Breast Cancer Res Treat 2009;116:79-90.
-
(2009)
Breast Cancer Res Treat
, vol.116
, pp. 79-90
-
-
Eck, S.M.1
Hoopes, P.J.2
Petrella, B.L.3
-
37
-
-
0035049886
-
Chemotherapy of metastatic breast cancer: What to expect in 2001 and beyond
-
Esteva FJ, Valero V, Pusztai L, et al. Chemotherapy of metastatic breast cancer: what to expect in 2001 and beyond. Oncologist 2001;6:133-46.
-
(2001)
Oncologist
, vol.6
, pp. 133-146
-
-
Esteva, F.J.1
Valero, V.2
Pusztai, L.3
-
38
-
-
0037317393
-
Does local surgery have a role in the management of stage IV breast cancer?
-
Carmichael AR, Anderson ED, Chetty U, et al. Does local surgery have a role in the management of stage IV breast cancer? Eur J Surg Oncol 2003;29:17-9.
-
(2003)
Eur J Surg Oncol
, vol.29
, pp. 17-19
-
-
Carmichael, A.R.1
Anderson, E.D.2
Chetty, U.3
|