Clinical relevance and diversity of two homologous genes encoding glycosyltransferases in Helicobacter pylori

Journal of Clinical Microbiology

Volumn 48, Issue 8, 2010, Pages 2885-2891

  Oleastro, Mónica ^a,b   Santos, Andrea ^a   Cordeiro, Rita ^a   Nunes, Baltazar ^a   Mégraud, Francis ^b   Ménard, Armelle ^b  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA (1,3) GALACOTSYLTRANSFERASE; GLYCOSYLTRANSFERASE; LIPOPOLYSACCHARIDE; UNCLASSIFIED DRUG; BACTERIAL DNA; VIRULENCE FACTOR;

ALLELE; ARTICLE; BACTERIAL GENE; BACTERIAL VIRULENCE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENE SYNTHESIS; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HELICOBACTER PYLORI; HOMOLOGOUS RECOMBINATION; HUMAN; IN VITRO STUDY; JHP0562 GENE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OPEN READING FRAME; OUTCOME ASSESSMENT; PEPTIC ULCER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; ADOLESCENT; CHEMISTRY; CHILD; CLUSTER ANALYSIS; DNA SEQUENCE; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENETICS; HELICOBACTER INFECTION; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PATHOGENICITY; PATHOLOGY;

ADOLESCENT; CHILD; CLUSTER ANALYSIS; DNA, BACTERIAL; FEMALE; GENE EXPRESSION PROFILING; GENETIC VARIATION; GLYCOSYLTRANSFERASES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; VIRULENCE FACTORS;

EID: 77955441900     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00401-10     Document Type: Article

References (40)

1. Akopyants, N. S., S. W. Clifton, D. Kersulyte, J. E. Crabtree, B. E. Youree, C. A. Reece, N. O. Bukanov, E. S. Drazek, B. A. Roe, and D. E. Berg. 1998. Analyses of the cag pathogenicity island of Helicobacter pylori. Mol. Microbiol. 28:37-53.
2. Alm, R. A., L. S. L. Ling, D. T. Moir, B. L. King, E. D. Brown, P. C. Doig, D. R. Smith, B. Noonan, B. C. Guild, B. L. deJonge, G. Carmel, P. J. Tummino, A. Caruso, M. Uria-Nickelsen, D. M. Mills, C. Ives, R. Gibson, D. Merberg, S. D. Mills, Q. Jiang, D. E. Taylor, G. F. Vovis, and T. J. Trust. 1999. Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature 397:176-180.
3. Appelmelk, B. J., M. C. Martino, E. Veenhof, M. A. Monteiro, J. J. Maaskant, R. Negrini, F. Lindh, M. Perry, G. Del Giudice, and C. M. J. E. Vandenbroucke-Grauls. 2000. Phase variation in H type I and Lewis a epitopes of Helicobacter pylori lipopolysaccharide. Infect. Immun. 68:5928-5932.
4. Appelmelk, B. J., and C. M. J. E. Vandenbroucke-Grauls. 2000. H. pylori and Lewis antigens. Gut 47:10-11.
5. Atherton, J. C., P. Cao, R. M. Peek, M. K. R. Tummuru, M. J. Blaser, and T. L. Cover. 1995. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori - association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem. 270:17771-17777.
6. Cao, P., and T. L. Cover. 2002. Two different families of hopQ alleles in Helicobacter pylori. J. Clin. Microbiol. 40:4504-4511.
7. Cao, P., K. J. Lee, M. J. Blaser, and T. L. Cover. 2005. Analysis of hopQ alleles in East Asian and Western strains of Helicobacter pylori. FEMS Microbiol. Lett. 251:37-43.
8. Correa, P., J. Fox, E. Fontham, B. Ruiz, Y. Lin, D. Zavala, N. Taylor, D. Mackinley, E. De Lima, H. Portilla, and G. Zarama. 1990. Helicobacter pylori and gastric carcinoma. Cancer 66:2569-2574.
9. Doig, P., B. L. de Jonge, R. A. Alm, E. D. Brown, M. Uria-Nickelsen, B. Noonan, S. D. Mills, P. Tummino, G. Carmel, B. C. Guild, D. T. Moir, G. F. Vovis, and T. J. Trust. 1999. Helicobacter pylori physiology predicted from genomic comparison of two strains. Microbiol. Mol. Biol. Rev. 63:675-707.
10. Dossumbekova, A., C. Prinz, J. Mages, R. Lang, J. G. Kusters, A. H. Van Vliet, W. Reindl, S. Backert, D. Saur, R. M. Schmid, and R. Rad. 2006. Helicobacter pylori HopH (OipA) and bacterial pathogenicity: genetic and functional genomic analysis of hopH gene polymorphisms. J. Infect. Dis. 194:1346-1355. (Pubitemid 44706502)
11. Edwards, N. J., M. A. Monteiro, G. Faller, E. J. Walsh, A. P. Moran, I. S. Roberts, and N. J. High. 2000. Lewis X structures in the O antigen side-chain promote adhesion of Helicobacter pylori to the gastric epithelium. Mol. Microbiol. 35:1530-1539.
12. Gerhard, M., N. Lehn, N. Neumayer, T. Boren, R. Rad, W. Schepp, S. Miehlke, M. Classen, and C. Prinz. 1999. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc. Natl. Acad. Sci. U. S. A. 96:12778-12783.
13. González-Valencia, G., J. C. Atherton, O. Muñoz, M. Dehesa, A. Madrazo de la Garza, and J. Torres. 2000. Helicobacter pylori vacA and cagA genotypes in Mexican adults and children. J. Infect. Dis. 182:1450-1454.
14. Heneghan, M. A., C. F. McCarthy, and A. P. Moran. 2000. Relationship of blood group determinants on Helicobacter pylori lipopolysaccharide with host Lewis phenotype and inflammatory response. Infect. Immun. 68:937-941.
15. Huang, X., and M. Miller. 1991. A time-efficient, linear-space local similarity algorithm. Adv. Appl. Math. 12:337-357.
16. Kuipers, E. J., A. M. Uyterlinde, A. S. Pena, R. Roosendaal, G. Pals, G. F. Nelis, H. P. M. Festen, and S. G. M. Meuwissen. 1995. Long-term sequelae of Helicobacter pylori gastritis. Lancet 345:1525-1528.
17. Lehours, P., A. Ménard, S. Dupouy, B. Bergey, F. Richy, F. Zerbib, A. Ruskone-Fourmestraux, J. C. Delchier, and F. Mégraud. 2004. Evaluation of the association of nine Helicobacter pylori virulence factors with strains involved in low-grade gastric mucosa-associated lymphoid tissue lymphoma. Infect. Immun. 72:880-888.
18. Li, J., Z. Ou, F. Wang, Y. Guo, R. Zhang, J. Zhang, P. Li, W. Xu, and Y. He. 2009. Distinctiveness of the cagA genotype in children and adults with peptic symptoms in South China. Helicobacter 14:248-255.
19. Mégraud, F., and H. Lamouliatte. 1992. Helicobacter pylori and duodenal ulcer. Evidence suggesting causation. Dig. Dis. Sci. 37:769-772.
20. Mégraud, F., N. Lehn, T. Lind, E. Bayerdorffer, C. O'Morain, R. Spiller, P. Unge, S. V. Van Zanten, M. Wrangstadh, and C. F. Burman. 1999. Antimicrobial susceptibility testing of Helicobacter pylori in a large multicenter trial: the MACH 2 study. Antimicrob. Agents Chemother. 43:2747-2752.
21. Ménard, A., A. Santos, F. Mégraud, and M. Oleastro. 2002. PCR-restriction fragment length polymorphism can also detect point mutation A2142C in the 23S rRNA gene, associated with Helicobacter pylori resistance to clarithromycin. Antimicrob. Agents Chemother. 46:1156-1157.
22. Monteiro, M. A., B. J. Appelmelk, D. A. Rasko, A. P. Moran, S. O. Hynes, L. L. MacLean, K. H. Chan, F. St. Michael, S. M. Logan, J. O'Rourke, A. Lee, D. E. Taylor, and M. B. Perry. 2000. Lipopolysaccharide structures of Helicobacter pylori genomic strains 26695 and J99, mouse model H. pylori Sydney strain, H. pylori P466 carrying sialyl Lewis X, and H. pylori UA915 expressing Lewis B-classification of H. pylori lipopolysaccharides into glycotype families. Eur. J. Biochem. 267:305-320.
23. Monteiro, M. A., K. H. N. Chan, D. A. Rasko, D. E. Taylor, P. Y. Zheng, B. J. Appelmelk, H. P. Wirth, M. Q. Yang, M. J. Blaser, S. O. Hynes, A. P. Moran, and M. B. Perry. 1998. Simultaneous expression of type 1 and type 2 Lewis blood group antigens by Helicobacter pylori lipopolysaccharides. J. Biol. Chem. 273:11533-11543.
24. Oh, J. D., H. Kling-Backhed, M. Giannakis, J. Xu, R. S. Fulton, L. A. Fulton, H. S. Cordum, C. Wang, G. Elliott, J. Edwards, E. R. Mardis, L. G. Engstrand, and J. I. Gordon. 2006. The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression. Proc. Natl. Acad. Sci. U. S. A. 103:9999-10004.
25. Oleastro, M., R. Cordeiro, J. Ferrand, B. Nunes, P. Lehours, I. Carvalho- Oliveira, A. I. Mendes, D. Penque, L. Monteiro, F. Mégraud, and A. Ménard. 2008. Evaluation of the clinical significance of homB, a novel candidate marker of Helicobacter pylori strains associated with peptic ulcer disease. J. Infect. Dis. 198:1379-1387.
26. Oleastro, M., R. Cordeiro, Y. Yamaoka, D. Queiroz, F. Mégraud, L. Monteiro, and A. Ménard. 2009. Disease association with two Helicobacter pylori duplicate outer membrane protein genes, homB and homA. Gut Pathog. 1:12.
27. Oleastro, M., L. Monteiro, P. Lehours, F. Mégraud, and A. Ménard. 2006. Identification of markers for Helicobacter pylori strains isolated from children with peptic ulcer disease by suppressive subtractive hybridization. Infect. Immun. 74:4064-4074.
28. Parsonnet, J., S. Hansen, L. Rodriguez, A. B. Gelb, R. A. Warnke, E. Jellum, N. Orentreich, J. H. Vogelman, and G. D. Friedman. 1994. Helicobacter pylori infection and gastric lymphoma. N. Engl. J. Med. 330:1267-1271.
29. Peck, B., M. Ortkamp, K. D. Diehl, E. Hundt, and B. Knapp. 1999. Conservation, localization and expression of HopZ, a protein involved in adhesion of Helicobacter pylori. Nucleic Acids Res. 27:3325-3333. (Pubitemid 29381326)
30. Pohl, M., and M. J. Blaser. 2009. A role for the beta-(1,3)galT upstream homolog, jhp0562, in Helicobacter pylori Lewis antigen synthesis, abstr. P-113, p. 111. 15th Int. Workshop Campylobacter Helicobacter Related Organisms. International Workshop on Campylobacter, Helicobacter, and Related Organisms, Niigata, Japan.
31. Pohl, M., J. Romero-Gallo, J. Guruge, D. Tse, J. Gordon, and M. Blaser. 2009. Host-dependent Lewis (Le) antigen expression in Helicobacter pylori cells recovered from Leb-transgenic mice. J. Exp. Med. 206:3061-3072.
32. Salaün, L., S. Ayraud, and N. J. Saunders. 2005. Phase variation mediated niche adaptation during prolonged experimental murine infection with Helicobacter pylori. Microbiology 151:917-923. (Pubitemid 40425025)
33. Salaün, L., B. Linz, S. Suerbaum, and N. J. Saunders. 2004. The diversity within an expanded and redefined repertoire of phase-variable genes in Helicobacter pylori. Microbiology 150(Pt. 4):817-830. (Pubitemid 38519303)
34. Talarico, S., B. Gold, J. Fero, D. Thompson, J. Guarner, S. Czinn, and N. Salama. 2009. Pediatric Helicobacter pylori isolates display distinct gene coding capacities and virulence gene marker profiles. J. Clin. Microbiol. 47:1680-1688.
35. Tomb, J. F., O. White, A. R. Kerlavage, R. A. Clayton, G. G. Sutton, R. D. Fleischmann, K. A. Ketchum, H. P. Klenk, S. Gill, B. A. Dougherty, K. Nelson, J. Quackenbush, L. Zhou, E. F. Kirkness, S. Peterson, B. Loftus, D. Richardson, R. Dodson, H. G. Khalak, A. Glodek, K. McKenney, L. M. Fitzegerald, N. Lee, M. D. Adams, E. K. Hickey, D. E. Berg, J. D. Gocayne, T. R. Utterback, J. D. Peterson, J. M. Kelley, M. D. Cotton, J. M. Weidman, C. Fujii, C. Bowman, L. Watthey, E. Wallin, W. S. Hayes, M. Borodovsky, P. D. Karp, H. O. Smith, C. M. Fraser, and J. C. Venter. 1997. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388: 539-547.
36. Tummuru, M. K. R., T. L. Cover, and M. J. Blaser. 1993. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect. Immun. 61:1799-1809.
37. van Doorn, L., C. Figueiredo, R. Sanna, A. Plaisier, P. Schneeberger, W. De Boer, and W. Quint. 1998. Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology 115:58-66.
38. Wirth, H., M. Yang, E. Sanabria-Valentín, D. Berg, A. Dubois, and M. Blaser. 2006. Host Lewis phenotype-dependent Helicobacter pylori Lewis antigen expression in rhesus monkeys. FASEB J. 20:1534-1536.
39. Wirth, H. P., M. Q. Yang, R. M. Peek, K. T. Tham, and M. J. Blaser. 1997. Helicobacter pylori Lewis expression is related to the host Lewis phenotype. Gastroenterology 113:1091-1098.
40. Yamaoka, Y., S. Kikuchi, H. M. T. El-Zimaity, O. Gutierrez, M. S. Osato, and D. Y. Graham. 2002. Importance of Helicobacter pylori oipA in clinical presentation, gastric inflammation, and mucosal interleukin 8 production. Gastroenterology 123:414-424.