Synthesis and evaluation of a new series of Neuropeptide S receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 15, 2010, Pages 4700-4703

  Melamed, Jeffrey Y ^a,c   Zartman, Amy E ^a   Kett, Nathan R ^a   Gotter, Anthony L ^a   Uebele, Victor N ^a   Reiss, Duane R ^a   Condra, Cindra L ^a   Fandozzi, Christine ^a   Lubbers, Laura S ^a   Rowe, Blake A ^a   McGaughey, Georgia B ^a   Henault, Martin ^b   Stocco, Rino ^b   Renger, John J ^a   Hartman, George D ^a   Bilodeau, Mark T ^a   Trotter, B Wesley ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Merck Canada   (Canada)

^c Synthonix Inc Inc   (United States)

Author keywords

Neuropeptide S receptor

Indexed keywords

IODINE 125; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE S; RECEPTOR BLOCKING AGENT;

ARTICLE; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; NONHUMAN; RAT; SYNTHESIS;

ANIMALS; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; HUMANS; IODINE RADIOISOTOPES; PROTEIN BINDING; QUINOLONES; RATS; RECEPTORS, NEUROPEPTIDE; STRUCTURE-ACTIVITY RELATIONSHIP;

RATTUS;

EID: 77955430323     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.143     Document Type: Article

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