Development and application of a validated stability-indicating HPLC method for simultaneous determination of granisetron hydrochloride, benzyl alcohol and their main degradation products in parenteral dosage forms

Talanta

Volumn 82, Issue 1, 2010, Pages 184-195

  Hewala, Ismail ^a   El Fatatre, Hamed ^b   Emam, Ehab ^c   Mubrouk, Mokhtar ^b  

^a Alexandria University Faculty of Pharmacy   (Egypt)

^b Tanta University   (Egypt)

^c Alexandria Company for Pharmaceuticals   (Egypt)

Author keywords

Benzyl alcohol; Degradation; Granisetron hydrochloride; Purity assessment; Spectrogram

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOTODIODES; SPECTROGRAPHS;

BENZYL ALCOHOL; DEVELOPMENT AND APPLICATIONS; GRANISETRON HYDROCHLORIDE; PHOTODIODE ARRAY DETECTIONS; PURITY ASSESSMENT; REVERSED-PHASE HIGH PERFORMANCE; SIMULTANEOUS DETERMINATIONS; SPECTROGRAMS;

DEGRADATION;

EID: 77955425529     PISSN: 00399140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.talanta.2010.04.017     Document Type: Article

References (23)

1. V. Kirchner, M. Aapro, J.P. Terrey, and P. Alberto Eur. J. Cancer 33 1997 1605
2. D.R. Cupissol, B. Serrou, and M. Coubel Eur. J. Cancer 26 Suppl. 1 1990 S 23
3. Physicians Disk Reference 57th edn. 2003 Thomson Montvale, NJ 076451742
4. B.Y. Xia, Q. Wu, and G.W. He Yaowu Fenzi Zezhi 20 2000 257
5. H.L. Zhang, L. Ye, and J.T. Stewart J. Liq. Chromatogr. Relat. Technol. 21 1998 2375
6. C.T. Huang, K.C. Chen, C.F. Chen, and T.H. Isai J. Chromatogr. B 716 1998 251
7. I. Wada, M. Satoh, T. Takeda, T. Nakabayashi, T. Honma, H. Saitoh, M. Takada, and K. Hirano Biol. Pharm. Bull. 21 1998 535
8. J.S. McElvain, V.J. Vandiver, and L.S. Eichmeier J. Pharm. Biomed. Anal. 15 1997 513
9. F. Pinguet, F. Bressolle, P. Martel, D. Salabert, and C. Astre J. Chromatogr. B 675 1996 99
10. V.K. Boppana J. Chromatogr. A 692 1995 195
11. S. Kudoh, T. Sato, H. Okada, H. Kumakura, and H. Nakamura J. Chromatogr. B 660 1994 205
12. C.T. Huang, C.C. Chen, and T.H. Tsai J. Liq. Chromatogr. Relat. Technol. 22 1999 2815
13. B.R. Capacio, C.E. Byers, T.K. Jackson, and R.L. Matthews J. Anal. Toxicol. 17 1993 151
14. V.K. Boppana, C. Miller-Stein, and W.H. Schaefer J. Chromatogr. B 678 1996 227
15. Y. Jiang, M. Lin, G. Fan, Y. Chen, Z. Li, W. Zhao, Y. Wu, and J. Hu J. Pharm. Biomed. Anal. 42 2006 464
16. Y. Dotsikas, C. Kousoulos, G. Tsatsou, and Y. Loukas J. Chromatogr. B 836 2006 79
17. S. Xiang, W. Wang, B. Xiang, H. Deng, and S. Xie Int. J. Mass Spectrom. 262 2007 174
18. C. Wang, G. Fan, M. Lin, Y. Chen, W. Zhao, and Y. Wu J. Chromatogr. B 850 2007 101
19. P. Bruijin, I. Mohaddam Helmantel, M. Jonge, T. Meyer, M. Lam, J. Verweij, E. Wiemer, and W. Loos J. Pharm. Biomed. Anal. 50 2009 977
20. British Pharmacopoeia 2008 Her Majesty's Stationary Office London, UK
21. United States Pharmacopoeia 31st edn. 2008 The United States Pharmacopoeia Convention Rockville, USA
22. International Conference on Harmonization (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use, Topic Q 2 (R1): Validation of Analytical Procedures: Text and Methodology, Geneva, 2005.
23. I. Hewala, J. Chromatogr. A, unpublished data.