Docking and SAR studies of salacinol derivatives as α-glucosidase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 15, 2010, Pages 4420-4423

  Nakamura, Shinya ^a   Takahira, Kazunori ^a   Tanabe, Genzoh ^a   Morikawa, Toshio ^a   Sakano, Mika ^a   Ninomiya, Kiyofumi ^a   Yoshikawa, Masayuki ^b   Muraoka, Osamu ^a   Nakanishi, Isao ^a  

^a KINKI UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Glucosidase; Antidiabetic drug; Docking study; Structure activity relationship

Indexed keywords

ACARBOSE; ALPHA GLUCOSIDASE INHIBITOR; CASUARINE; KOTALANOL; NEOSALACINOL; SALACINOL; SALAPRINOL; UNCLASSIFIED DRUG; VOGLIBOSE;

ACCURACY; ARTICLE; COMPLEX FORMATION; DRUG BINDING SITE; DRUG DESIGN; NONHUMAN; PREDICTION; SIMULATION; STRUCTURE ACTIVITY RELATION;

ALPHA-GLUCOSIDASES; BINDING SITES; COMPUTER SIMULATION; DRUG DESIGN; ENZYME INHIBITORS; HYDROGEN BONDING; SALACIA; STRUCTURE-ACTIVITY RELATIONSHIP; SUGAR ALCOHOLS; SULFATES; THERMODYNAMICS;

SALACIA RETICULATA;

EID: 77955423546     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.06.059     Document Type: Article

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