On the domain pairing in chimeric antibodies

Molecular Immunology

Volumn 47, Issue 14, 2010, Pages 2422-2426

  Teplyakov, Alexey ^a   Obmolova, Galina ^a   Carton, Jill M ^a   Gao, Wei ^a   Zhao, Yonghong ^a   Gilliland, Gary L ^a  

^a CENTOCOR INC   (United States)

Author keywords

Antibody; Chimera; Crystal structure; Domain interface

Indexed keywords

CHIMERIC ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT;

ANTIGEN BINDING; ANTIGEN STRUCTURE; ARTICLE; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; X RAY ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; BASE SEQUENCE; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

MAMMALIA;

EID: 77955422553     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.05.002     Document Type: Article

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