HDL cholesterol is a strong determinant of endothelial progenitor cells in hypercholesterolemic subjects

Microvascular Research

Volumn 80, Issue 2, 2010, Pages 274-279

  Rossi, Fabio ^a   Bertone, Cora ^a   Montanile, Federica ^a   Miglietta, Federica ^a   Lubrano, Carla ^a   Gandini, Loredana ^a   Santiemma, Vittorio ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Cardiovascular risk factor; Endothelial Function; Endothelium dependent vasodilatation; EPC; Gender; HDL C; Hypercholesterolemia; LDL C; Plethysmography

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGE; ARTICLE; CELL COUNT; CELL MIGRATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; FEMALE; FOREARM BLOOD FLOW; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; STEM CELL; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 77955419461     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2010.05.003     Document Type: Article

References (44)

1. Adams V., Lenk K., Linke A., Lenz D., Erbs S., Sandri M., Tarnok A., Gielen S., Emmrich F., Schuler G., Hambrecht R. Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia. Arterioscler. Thromb. Vasc. Biol. 2004, 24:684-690.
2. Amarenco P., Labreuche J. Lipid management in the prevention of stroke, review and updated meta-analysis of statins for stroke prevention. Lancet Neurol. 2009, 8:453-463.
3. Asahara T., Murohara T., Sullivan A., Silver M., van der Zee R., Li T., Witzenbichler B., Schatteman G., Isner J.M. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997, 275:964-967.
4. Assmann G., Schulte H., von Eckardstein A., Huang Y. High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis 1996, 124:S11-S20.
5. Bahlmann F.H., De Groot K., Spandau J.M., Landry A.L., Hertel B., Duckert T., Boehm S.M., Menne J., Haller H., Fliser D. Erythropoietin regulates endothelial progenitor cells. Blood 2004, 103:921-926.
6. Baigent C., Keech A., Kearney P.M., Blackwell L., Buck G., Pollicino C., Kirby A., Sourjina T., Peto R., Collins R., Simes R. Efficacy and safety of cholesterol lowering treatment, prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins. Lancet 2005, 366:1267-1278.
7. Bisoendial R.J., Hovingh G.K., Levels J.H., Lerch P.G., Andresen I., Hayden M.R., Kastelein J.J., Stroes E.S. Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein. Circulation 2003, 107:2944-2948.
8. Chen J.Z., Zhang F.R., Tao Q.M., Wang X.X., Zhu J.H., Zhu J.H. Number and activity of endothelial progenitor cells from peripheral blood in patients with hypercholesterolaemia. Clin. Sci. 2004, 107:273-280.
9. Collins P., Rosano G.M., Sarrel P.M., Ulrich L., Adamopoulos S., Beale C.M., McNeill J.G., Poole-Wilson P.A. 17β-Estradiol attenuates acetyl-choline-induced coronary arterial constriction in women but not men with coronary artery disease. Circulation 1995, 92:24-30.
10. Dimmeler S., Aicher A., Vasa M., Mildner-Rihm C., Adler K., Tiemann M., Rutten H., Fichtlscherer S., Martin H., Zeiher A.M. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J. Clin. Investig. 2001, 108:391-397.
11. Fadini G.P., Agostini C., Sartore S., Avogaro A. Endothelial progenitor cells in the natural history of atherosclerosis. Atherosclerosis 2007, 194:46-54.
12. Fadini G.P., Baesso I., Albiero M., Sartore S., Agostini C., Avogaro A. Technical notes on endothelial progenitor cells: ways to escape from the knowledge plateau. Atherosclerosis 2008, 197:496-503.
13. Gilligan D.M., Quyyumi A.A., Cannon R.O. Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women. Circulation 1994, 89:2545-2551.
14. Gordon D.J., Rifkind B.M. High-density lipoprotein-the clinical implications of recent studies. N Engl J. Med. 1989, 321:1311-1316.
15. Gordon T., Castelli W.P., Hjortland M.C., Kannel W.B., Dawber T.R. High density lipoprotein as a protective factor against coronary heart disease. Am. J. Med. 1977, 62:707-714.
16. Grisar J., Aletaha D., Steiner C.W., Kapral T., Steiner S., Seidinger D., Weigel G., Schwarzinger I., Wolozcszuk W., Steiner G., Smolen J.S. Depletion of endothelial progenitor cells in the peripheral blood of patients with rheumatoid arthritis. Circulation 2005, 111:204-211.
17. Herbrig K., Haensel S., Oelschlaegel U., Pistrosch F., Foerster S., Passauer J. Endothelial dysfunction in patients with rheumatoid arthritis is associated with a reduced number and impaired function of endothelial progenitor cells. Ann. Rheum. Dis. 2006, 65:157-163.
18. Higashi Y., Maysuoka H., Umei H., Sugano R., Fujii Y., Soga J., Kihara Y., Chayama K., Imaizumi T. Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells. Am. J. Physiol. Endocrinol. Metab. 2009, 10.1152/ajpendo.00394.2009 [doi].
19. Higashi Y., Noma K., Yoshizumi M., Kihara Y. Endothelial function and oxidative stress in cardiovascular diseases. Circ. J. 2009, 73:411-418.
20. Hill J.M., Zalos G., Halcox J.P., Schenke W.H., Waclawiw M.A., Quyyumi A.A., Finkel T. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J. Med. 2003, 348:593-600.
21. Hirsch E.Z., Chisolm G.M., With H.M. Reendothelialization and maintenance of endothelial integrity in longitudinal denuded tracks in the thoracic aorta of rats. Atherosclerosis 1983, 46:287-307.
22. Kong D., Melo L.G., Gnecchi M., Zhang L., Mostoslavsky G., Liew C.C., Pratt R.E., Dzau V.J. Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries. Circulation 2004, 110:2039-2046.
23. Lefèvre J., Michaud S.E., Haddad P., Dussault S., Ménard C., Groleau J., Turgeon J., Rivard A. Moderate consumption of red wine (cabernet sauvignon) improves ischemia-induced neovascularization in ApoE-deficient mice, effect on endothelial progenitor cells and nitric oxide. FASEB J. 2007, 21:3845-3852.
24. Lerman A., Zeiher A.M. Endothelial function, cardiac events. Circulation 2005, 111:363-368.
25. Mijatovic V., Pines A., Stehouwer C.D.A., van der Mooren M.J., Kenemans P. The effects of oestrogen on vessel wall and cardiac function, haemostasis and homocysteine metabolism. Eur Menopause J. 1996, 3:209-218.
26. Mineo C., Yuhanna I.S., Quon M.J., Shaul P.W. High density lipoprotein induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases. J. Biol. Chem. 2003, 278:9142-9149.
27. Noor R., Shuaib U., Wang C.X., Todd K., Ghani U., Schwindt B., Shuaib A. High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis. Atherosclerosis 2007, 192:92-99.
28. Pasimeni G., Ribaudo M.C., Capoccia D., Rossi F., Bertone C., Leonetti F., Santiemma V. Non-invasive evaluation of endothelial dysfunction in uncomplicated obesity, relationship with insulin resistance. Microvasc. Res. 2006, 71:115-120.
29. Peichev M., Naiyer A.J., Pereira D., Zhu Z., Lane W.J., Williams M., Oz M.C., Hicklin D.J., Witte L., Moore M.A., Rafii S. Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors. Blood 2000, 95:952-958.
30. Pines A., Fisman E.Z., Shapira I., Drory Y., Weiss A., Eckstein N., Levo Y., Averbuch M., Motro M., Rotmensch H.H., Ayalon D. Exercise echocardiography in postmenopausal hormone users with mild hypertension. Am. J. Cardiol. 1996, 78:1385-1389.
31. Pirro M., Schillaci G., Paltriccia R., Bagaglia F., Menecali C., Mannarino M.R., Capanni M., Velardi A., Mannarino E. Increased ratio of CD31/CD42- microparticles to endothelial progenitors as a novel marker of atherosclerosis in hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol. 2006, 26:2530-2535.
32. Romagni P., Rossi F., Guerrini L., Quirini C., Santiemma V. Aldosterone induces contraction of the resistance arteries in man. Atherosclerosis 2003, 166:345-349.
33. Rossi F., Bertone C., Petricca S., Santiemma V. Ghrelin inhibits angiotensin II-induced migration of human aortic endothelial cells. Atherosclerosis 2007, 192:291-297.
34. Skafar D.F., Xu R., Morales J., Ram J., Sowers J.R. Clinical review 91, Female sex hormones and cardiovascular disease in women. J. Clin. Endocrinol. Metab. 1997, 82:3913-3918.
35. Tepper O.M., Galiano R.D., Capla J.M., Kalka C., Gagne P.J., Jacobowitz G.R., Levine J.P., Gurtner G.C. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002, 106:2781-2786.
36. Urbich C., Dimmeler S. Endothelial progenitor cells, characterization and role in vascular biology. Circ. Res. 2004, 95:343-353.
37. Vasa M., Fichtlscherer S., Aicher A., Adler K., Urbich C., Martin H., Zeiher A.M., Dimmeler S. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ. Res. 2001, 89:e1-e7.
38. Walldius G., Jungner I. Apolipoprotein B and apolipoprotein A-I, risk indicators of coronary heart disease and targets for lipid-modifying therapy. J. Intern. Med. 2004, 255:188-205.
39. Werner N., Priller J., Laufs U., Endres M., Böhm M., Dirnagl U., Nickenig G. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation, effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler. Thromb. Vasc. Biol. 2002, 22:567-572.
40. White M.M., Zamudio S., Stevens T., Tyler R., Lindenfeld J., Leslie K., Moore L.G. Estrogen, progesterone, and vascular reactivity, potential cellular mechanisms. Endocr. Rev. 1995, 6:739-751.
41. Wilensky R.L., Macphee C.H. Lipoprotein-associated phospholipase A(2) and atherosclerosis. Curr. Opin. Lipidol. 2009, 20:415-420.
42. Wu Y., Wang Q., Cheng L., Wang J., Lu G. Effect of oxidized low-density lipoprotein on survival and function of endothelial progenitor cell mediated by p38 signal pathway. J. Cardiovasc. Pharmacol. 2009, 53:151-156.
43. Yu X., Song M., Chen J., Zhu G., Zhao G., Wang H., Hunag L. Hepatocyte growth factor protects endothelial progenitor cell from damage of low-density lipoprotein cholesterol via the PI3K/Akt signaling pathway. Mol. Biol. Rep. 2009, 10.1007/s11033-009-9753-6.
44. Zhou B., Ma F.X., Liu P.X., Fang Z.H., Wang S.L., Han Z.B., Poon M.C., Han Z.C. Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase. J. Lipid Res. 2006, 47:1227-1237.