Assembly of the flagellum and its role in cell morphogenesis in Trypanosoma brucei

Current Opinion in Microbiology

Volumn 13, Issue 4, 2010, Pages 453-458

  Vaughan, Sue ^a  

^a OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GROWTH; CELL MOTILITY; CELL SHAPE; CYTOKINESIS; FLAGELLUM; LIFE CYCLE; MORPHOGENESIS; NONHUMAN; REVIEW; TRYPANOSOMA BRUCEI;

ANIMALS; CELL SHAPE; CYTOKINESIS; FLAGELLA; HOST-PARASITE INTERACTIONS; MORPHOGENESIS; TRYPANOSOMA BRUCEI BRUCEI; TSETSE FLIES;

EUKARYOTA; PROTOZOA; TRYPANOSOMA BRUCEI;

EID: 77955418160     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mib.2010.05.006     Document Type: Review

References (45)

1. Sherwin T., Gull K. The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations. Philos Trans R Soc Lond Ser B Biol Sci 1989, 323:573-588.
2. Woodward R., Gull K. Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci 1990, 95(Pt 1):49-57.
3. Gull K. The cytoskeleton of trypanosomatid parasites. Ann Rev Microbiol 1999, 53:629-655.
4. Moreira-Leite F.F., Sherwin T., Kohl L., Gull K. A trypanosome structure involved in transmitting cytoplasmic information during cell division. Science 2001, 294:610-612.
5. Sonneborn T.M. The determinants and evolution of life. The differentiation of cells. PNAS 1964, 51:915-929.
6. Beisson J., Sonneborn T.M. Cytoplasmic inheritance of the organisation of the cell cortex in Paramecium aurelia. PNAS 1965, 53:275-282.
7. Beisson J. Preformed cell structure and cell heredity. Prion 2008, 2:1-8.
8. Ralston K.S., Kabututu Z.P., Melehani J.H., Oberholzer M., Hill K.L. The Trypanosoma brucei flagellum: moving parasites in new directions. Ann Rev Microbiol 2009, 63:335-362.
9. Portman N., Gull K. The paraflagellar rod of kinetoplastid parasites: from structure to components and function. Int J Parasitol 2010, 40:135-148.
10. Bastin P., Gull K. Assembly and function of complex flagellar structures illustrated by the paraflagellar rod of trypanosomes. Protist 1999, 150:113-123.
11. Kohl L., Sherwin T., Gull K. Assembly of the paraflagellar rod and the flagellum attachment zone complex during the Trypanosoma brucei cell cycle. J Eukaryot Microbiol 1999, 46:105-109.
12. Lacomble S., Vaughan S., Gadelha C., Morphew M.K., Shaw M.K., McIntosh J.R., Gull K. Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography. J Cell Sci 2009, 122:1081-1090.
13. Davidge J.A., Chambers E., Dickinson H.A., Towers K., Ginger M.L., McKean P.G., Gull K. Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formation. J Cell Sci 2006, 119:3935-3943.
14. Absalon S., Blisnick T., Kohl L., Toutirais G., Dore G., Julkowska D., Tavenet A., Bastin P. Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes. Mol Biol Cell 2008, 19:929-944.
15. Vaughan S., Kohl L., Ngai I., Wheeler R.J., Gull K. A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei. Protist 2008, 159:127-136.
16. Bastin P., Pullen T.J., Sherwin T., Gull K. Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1. J Cell Sci 1999, 112(Pt 21):3769-3777.
17. Kohl L., Robinson D., Bastin P. Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes. EMBO J 2003, 22:5336-5346.
18. Branche C., Kohl L., Toutirais G., Buisson J., Cosson J., Bastin P. Conserved and specific functions of axoneme components in trypanosome motility. J Cell Sci 2006, 119:3443-3455.
19. Absalon S., Kohl L., Branche C., Blisnick T., Toutirais G., Rusconi F., Cosson J., Bonhivers M., Robinson D., Bastin P. Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. PLoS One 2007, 2:e437.
20. Stephan A., Vaughan S., Shaw M.K., Gull K., McKean P.G. An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport. Traffic 2007, 8:1323-1330.
21. Absalon S., Blisnick T., Bonhivers M., Kohl L., Cayet N., Toutirais G., Buisson J., Robinson D., Bastin P. Flagellum elongation is required for correct structure, orientation and function of the flagellar pocket in Trypanosoma brucei. J Cell Sci 2008, 121:3704-3716.
22. Bonhivers M., Nowacki S., Landrein N., Robinson D.R. Biogenesis of the trypanosome endo-exocytotic organelle is cytoskeleton mediated. PLoS Biol 2008, 6:e105.
23. LaCount D.J., Barrett B., Donelson J.E. Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis. J Biol Chem 2002, 277:17580-17588.
24. Sherwin T., Gull K. Visualization of detyrosination along single microtubules reveals novel mechanisms of assembly during cytoskeletal duplication in trypanosomes. Cell 1989, 57:211-221.
25. Baines A., Gull K. WCB is a C2 domain protein defining the plasma membrane-sub-pellicular microtubule corset of kinetoplastid parasites. Protist 2008, 159:115-125.
26. Casanova M., Crobu L., Blaineau C., Bourgeois N., Bastien P., Pages M. Microtubule-severing proteins are involved in flagellar length control and mitosis in Trypanosomatids. Mol Microbiol 2009, 71:1353-1370.
27. Ploubidou A., Robinson D.R., Docherty R.C., Ogbadoyi E.O., Gull K. Evidence for novel cell cycle checkpoints in trypanosomes: kinetoplast segregation and cytokinesis in the absence of mitosis. J Cell Sci 1999, 112(Pt 24):4641-4650.
28. Hammarton T.C., Clark J., Douglas F., Boshart M., Mottram J.C. Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin. J Biol Chem 2003, 278:22877-22886.
29. Tu X., Wang C.C. The involvement of two cdc2-related kinases (CRKs) in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J Biol Chem 2004, 279:20519-20528.
30. Glotzer M. The 3Ms of central spindle assembly: microtubules, motors and MAPs. Nat Rev Mol Cell Biol 2009, 10:9-20.
31. Robinson D.R., Sherwin T., Ploubidou A., Byard E.H., Gull K. Microtubule polarity and dynamics in the control of organelle positioning, segregation, and cytokinesis in the trypanosome cell cycle. J Cell Biol 1995, 128:1163-1172.
32. Li Z., Umeyama T., Wang C.C. The chromosomal passenger complex and a mitotic kinesin interact with the Tousled-like kinase in trypanosomes to regulate mitosis and cytokinesis. PLoS One 2008, 3:e3814.
33. Li Z., Lee J.H., Chu F., Burlingame A.L., Gunzl A., Wang C.C. Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei. PLoS One 2008, 3:e2354.
34. Robinson D.R., Gull K. Basal body movements as a mechanism for mitochondrial genome segregation in the trypanosome cell cycle. Nature 1991, 352:731-733.
35. Gluenz E., Sharma R., Carrington M., Gull K. Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages. Mol Microbiol 2008, 69:666-680.
36. Vickerman K. Developmental cycles and biology of pathogenic trypanosomes. Br Med Bull 1985, 41:105-114.
37. Matthews K.R., Sherwin T., Gull K. Mitochondrial genome repositioning during the differentiation of the African trypanosome between life cycle forms is microtubule mediated. J Cell Sci 1995, 108(Pt 6):2231-2239.
38. Matthews K.R., Gull K. Commitment to differentiation and cell cycle re-entry are coincident but separable events in the transformation of African trypanosomes from their bloodstream to their insect form. J Cell Sci 1997, 110(Pt 20):2609-2618.
39. Sharma R., Gluenz E., Peacock L., Gibson W., Gull K., Carrington M. The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly. Trends Parasitol 2009, 25:517-524.
40. Sharma R., Peacock L., Gluenz E., Gull K., Gibson W., Carrington M. Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes. Protist 2008, 159:137-151.
41. Farr H., Gull K. Functional studies of an evolutionarily conserved. Cytochrome b5 domain protein reveals a specific role in axonemal organisation and the general phenomenon of post-division axonemal growth in trypanosomes. Cell Motil Cytoskel 2009, 66:24-35.
42. LaCount D.J., Bruse S., Hill K.L., Donelson J.E. Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters. Mol Biochem Parasitol 2000, 111:67-76.
43. Kozminski K.G., et al. A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc Natl Acad Sci USA 1993, 90:5519-5523.
44. Pedersen L.B., Rosenbaum J.L. Intraflagellar Transport (IFT) role in ciliary assembly, resorption and signalling. Curr Top Dev Biol 2008, 85:23-61.
45. Pigino G., Geimer S., Lanzavecchia S., Paccagnini E., Cantele F., Diener D.R., Rosenbaum J.L., Lupetti P. Electron-tomographic analysis of intraflagellar transport particle trains in situ. J Cell Biol 2009, 187:135-148.